Amended and Restated Research Agreement Sample Contracts

Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions. AMENDED AND RESTATED RESEARCH AGREEMENT

Amended and Restated Research Agreement • September 12th, 2014 • Kolltan Pharmaceuticals Inc • Pharmaceutical preparations • Connecticut

• Contract Type
  Amended and Restated Research Agreement
• Filed
  September 12th, 2014
• Company
  Kolltan Pharmaceuticals Inc
• Industry
  Pharmaceutical preparations
• Jurisdiction
  Connecticut

This AMENDED AND RESTATED RESEARCH AGREEMENT (this “Agreement”) is entered into as of December 23, 2011 (the “Effective Date”), by and between Yale University, a non-profit corporation organized and existing under and by virtue of a special charter granted by the General Assembly of the Colony and State of Connecticut (the “University”), and KolltanPharmaceuticals, Inc., a Delaware corporation, having its principal offices at 300 George Street, Suite 530, New Haven, Connecticut 06511 (the “Sponsor”).

AMENDED AND RESTATED RESEARCH AGREEMENT

Amended and Restated Research Agreement • March 15th, 2007 • Combinatorx, Inc • Pharmaceutical preparations • Delaware

• Contract Type
  Amended and Restated Research Agreement
• Filed
  March 15th, 2007
• Company
  Combinatorx, Inc
• Industry
  Pharmaceutical preparations
• Jurisdiction
  Delaware

AMENDED AND RESTATED RESEARCH AGREEMENT (this “Agreement”), dated as of February 22, 2007, by and between CombinatoRx, Incorporated, a Delaware corporation (the “Company”), and CHDI, Inc., a New Jersey corporation (the “Foundation”). The Company and the Foundation shall hereinafter be referred to individually as a “Party” and collectively as the “Parties”.