0001628280-23-016425 Sample Contracts

EXECUTIVE EMPLOYMENT AGREEMENT
Executive Employment Agreement • May 8th, 2023 • Neoleukin Therapeutics, Inc. • Pharmaceutical preparations • Washington

This Executive Employment Agreement (the “Agreement”), made between Neoleukin Therapeutics, Inc., a Delaware corporation (the “Company”), and Sean Smith (the “Executive” and, collectively with the Company, the “Parties”), is entered into as of August 3, 2022 (the “Effective Date”).

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AMENDMENT NO. 1 TO EMPLOYMENT AGREEMENT
Employment Agreement • May 8th, 2023 • Neoleukin Therapeutics, Inc. • Pharmaceutical preparations

This Amendment No. 1 (this “Amendment”), dated as of April 3, 2023, amends that certain Employment Agreement (the “Agreement”), dated as of August 3, 2022, by and between Neoleukin Therapeutics, Inc., a Delaware corporation (the “Company”), and Sean Smith (the “Executive”). All capitalized terms not defined herein shall have the meanings assigned to them in the Agreement.

SEPARATION AGREEMENT AND RELEASE
Separation Agreement and Release • May 8th, 2023 • Neoleukin Therapeutics, Inc. • Pharmaceutical preparations • Washington

This Separation Agreement and Release (this “Agreement”) is made and entered into by and between Jonathan G. Drachman, MD (“Employee”) and Neoleukin Therapeutics, Inc. (the “Company”). The parties agree as follows:

SEPARATION AGREEMENT AND RELEASE
Separation Agreement and Release • May 8th, 2023 • Neoleukin Therapeutics, Inc. • Pharmaceutical preparations • California

This Separation Agreement and Release (this “Agreement”) is made and entered into by and between Priti Patel, M.D. (“Employee”) and Neoleukin Therapeutics, Inc. (the “Company”). The parties agree as follows:

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