0001437749-18-010953 Sample Contracts

AMENDMENT I TO EXCLUSIVE LICENSE AND DISTRIBUTION AGREEMENT
Exclusive License and Distribution Agreement • May 30th, 2018 • Nuo Therapeutics, Inc. • Surgical & medical instruments & apparatus

This AMENDMENT I (“Amendment”) is made and entered into as of May 28, 2018 (“Amendment Effective Date”), between Nuo Therapeutics, Inc., a Delaware corporation, with its principal office at 207A Perry Parkway, Suite 1, Gaithersburg, MD 20877 (“Nuo”), and Rohto Pharmaceutical Co., Ltd., a Japanese company, with its principal office at 1-8-1 Tatsumi-nishi, Ikuno-ku, Osaka 544-8666, Japan (“Rohto”). Each of Nuo and Rohto is hereinafter referred to as a “Party” and collectively the “Parties.”

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SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • May 30th, 2018 • Nuo Therapeutics, Inc. • Surgical & medical instruments & apparatus • Delaware

This Securities Purchase Agreement, dated on and as of May 28, 2018 (this “Agreement”), is made by and among Nuo Therapeutics, Inc., a Delaware corporation (the “Company”), and Rohto Pharmaceutical Co., Ltd., a Japanese corporation with its principal office at 1-8-1 Tatsumi-nishi, Ikuno-ku, Osaka Japan 544-8666, the undersigned purchaser (“Rohto”).

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