0001255294-11-000547 Sample Contracts

SECURITIES PURCHASE AGREEMENT By and Between OPTIMIZERx CORPORATION and VICIS CAPITAL MASTER FUND DATED SEPTEMBER 16, 2011 SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • September 21st, 2011 • OptimizeRx Corp • Services-business services, nec • Florida

This SECURITIES PURCHASE AGREEMENT (the “Agreement”), dated this 16th day of September 2011, is made by and between OPTIMIZERx CORPORATION, a Nevada corporation (the “Company”), and VICIS CAPITAL MASTER FUND (the “Purchaser”), a sub-trust of Vicis Capital Series Master Trust, a unit trust organized and existing under the laws of the Cayman Islands.

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Second AMENDED AND RESTATED REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • September 21st, 2011 • OptimizeRx Corp • Services-business services, nec • New York

This Second Amended and Restated Registration Rights Agreement (this “Agreement”) is made and entered into as of September 16, 2011, by and between OptimizeRx Corporation, a Nevada corporation (the “Company”), and Vicis Capital Master Fund, a sub-trust of Vicis Capital Series Master Trust, a unit trust organized and existing under the laws of the Cayman Islands (“Vicis”). Physicians Interactive Inc., a Delaware corporation (“PI”), which was a party to the Prior Agreement (as defined below), is not a party to this Agreement pursuant to that certain Termination Agreement and Release by and among the Company, OptimizeRx Corporation , a Michigan corporation, Vicis, Physicians Interactive Holdings, LLC, a Delaware limited liability corporation, and PI dated of even date herewith (the “Termination and Release”). This Agreement amends and restates the Prior Agreement.

THIRD AMENDED AND RESTATED SECURITY AGREEMENT
Security Agreement • September 21st, 2011 • OptimizeRx Corp • Services-business services, nec • New York

THIS THIRD AMENDED AND RESTATED SECURITY AGREEMENT (this “Security Agreement”) is made as of September 16, 2011 by and among OptimizeRx Corporation, a Nevada corporation (“Debtor”), and Vicis Capital Master Fund (“Vicis”), a sub-trust of Vicis Capital Series Master Trust, a unit trust organized and existing under the laws of the Cayman Islands, and amends and restates the 2010 Security Agreement (as defined below).

Amended and Restated GUARANTY AGREEMENT
Guaranty Agreement • September 21st, 2011 • OptimizeRx Corp • Services-business services, nec • Florida

THIS AMENDED AND RESTATED GUARANTY AGREEMENT (this “Guaranty”) is made as of September 16, 2011 by and between OptimizeRx Corporation, a Michigan corporation (“Guarantor”), and Vicis Capital Master Fund (“Vicis”), a sub-trust of Vicis Capital Series Master Trust, a unit trust organized and existing under the laws of the Cayman Islands.

Termination Agreement and Release
Termination Agreement and Release • September 21st, 2011 • OptimizeRx Corp • Services-business services, nec • New York

This Termination Agreement and Release (this “Agreement”) is made this 16th day of September, 2011, by and among OPTIMIZERx CORPORATION, a Nevada corporation (the “Company ”), OPTIMIZERx CORPORATION, a Michigan corporation (the “Guarantor”), VICIS CAPITAL MASTER FUND, a sub-trust of Vicis Capital Series Master Trust, a unit trust formed under the laws of the Cayman Islands (“Vicis”), Physicians Interactive Holdings, LLC, a limited liability company formed under the laws of the State of Delaware (“PIH”) and Physicians Interactive Inc., a Delaware corporation (“PI”).

Third Amended and Restated GUARANTOR SECURITY AGREEMENT
Guarantor Security Agreement • September 21st, 2011 • OptimizeRx Corp • Services-business services, nec • New York

THIS THIRD AMENDED and Restated GUARANTOR SECURITY AGREEMENT (this “Security Agreement”) is dated as of September 16, 2011, by and among OptimizeRx Corporation, a Michigan corporation (“Debtor”) and Vicis Capital Master Fund (“Vicis”), a sub-trust of Vicis Capital Series Master Trust, a unit trust organized and existing under the laws of the Cayman Islands, and amends and restates the 2010 Security Agreement (as defined below).

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