0001193125-26-387267 Sample Contracts

SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • September 10th, 2026 • Cerenome, Inc. • Surgical & medical instruments & apparatus • New York

This SECURITIES PURCHASE AGREEMENT (this “Agreement”), dated as of September 4, 2026, is by and among Cerenome, Inc., a Delaware corporation with offices located at 6420 Levit Green Boulevard, Suite 310, Houston, Texas 77021 (the “Company”), and each of the investors listed on the Schedule of Buyers attached hereto (individually, a “Buyer” and collectively, the “Buyers”).

REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • September 10th, 2026 • Cerenome, Inc. • Surgical & medical instruments & apparatus

This REGISTRATION RIGHTS AGREEMENT (this “Agreement”), dated as of September 10, 2026, is by and among Cerenome, Inc., a Delaware corporation with offices located at 6420 Levit Green Boulevard, Suite 310, Houston, Texas 77021 (the “Company”), and the undersigned buyers (each, a “Buyer,” and collectively, the “Buyers”).

SECURITY AND PLEDGE AGREEMENT
Security and Pledge Agreement • September 10th, 2026 • Cerenome, Inc. • Surgical & medical instruments & apparatus • New York

WHEREAS, the Company is party to that certain Securities Purchase Agreement, dated as of September 4, 2026, (as amended, modified, supplemented, extended, renewed, restated or replaced from time to time in accordance with the terms thereof, the “Securities Purchase Agreement”) by and among the Company and each party listed as a “Buyer” on the Schedule of Buyers attached thereto (each a “Buyer” and collectively, the “Buyers”), pursuant to which the Company shall be required to sell, and the Buyers shall purchase or have the right to purchase, the “Notes” issued pursuant thereto (as such Notes may be amended, modified, supplemented, extended, renewed, restated or replaced from time to time in accordance with the terms thereof, collectively, the “Notes”);

ROYALTY AGREEMENT dated as of September 10, 2026 by and among CERENOME, INC., CNSIDE DIAGNOSTICS, LLC, as the Payor Parties and 3i, LP, as the Payee
Royalty Agreement • September 10th, 2026 • Cerenome, Inc. • Surgical & medical instruments & apparatus • New York

This ROYALTY AGREEMENT (this “Agreement”), dated as of September 10, 2026, is by and among CNSide Diagnostics, LLC, a Delaware limited liability company (“CNSide”), Cerenome, Inc., a Delaware corporation (the “Parent,” and together with CNSide, the “Payor Parties”), and 3i, LP, a Delaware limited partnership (the “Payee”).