0001193125-18-251837 Sample Contracts

AMENDED AND RESTATED INVESTORS’ RIGHTS AGREEMENT
Investors’ Rights Agreement • August 17th, 2018 • Principia Biopharma Inc. • Pharmaceutical preparations • California

This Amended and Restated Investors’ Rights Agreement (this “Agreement”) is made as of August 16, 2018, by and among Principia Biopharma Inc., a Delaware corporation (the “Company”), and the persons and entities (each, an “Investor” and collectively, the “Investors”) listed on Exhibit A hereto.

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LEASE BRITANNIA POINTE GRAND BUSINESS PARK BRITANNIA POINTE GRAND LIMITED PARTNERSHIP a Delaware limited partnership, as Landlord, and PRINCIPIA BIOPHARMA, INC., a Delaware corporation, as Tenant.
Lease • August 17th, 2018 • Principia Biopharma Inc. • Pharmaceutical preparations • California

This Lease (the “Lease”), dated as of the date set forth in Section 1 of the Summary of Basic Lease Information (the “Summary”), below, is made by and between BRITANNIA POINTE GRAND LIMITED PARTNERSHIP, a Delaware limited partnership (“Landlord”), and PRINCIPIA BIOPHARMA, INC., a Delaware corporation (“Tenant”).

DEVELOPMENT AND LICENSE AGREEMENT between PRINCIPIA BIOPHARMA INC. and ABBVIE BIOTECHNOLOGY LIMITED Dated as of June 9, 2017
Development and License Agreement • August 17th, 2018 • Principia Biopharma Inc. • Pharmaceutical preparations • Delaware

This Development and License Agreement (the “Agreement”) is made and entered into effective as of June 9, 2017 (the “Effective Date”) by and between Principia Biopharma, Inc., a Delaware corporation (“Licensor”), and AbbVie Biotechnology Limited, a corporation organized under the laws of Bermuda having its place of business at Clarendon House, 2 Church Street, Hamilton HM11, Bermuda (“AbbVie”). Licensor and AbbVie are sometimes referred to herein individually as a “Party” and collectively as the “Parties.”

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