0001193125-16-422567 Sample Contracts

OMEROS CORPORATION Common Stock (par value $0.01 per share) At Market Issuance Sales Agreement
Omeros Corp • January 6th, 2016 • Pharmaceutical preparations • New York

Omeros Corporation, a Washington corporation (the “Company”), confirms its agreement (this “Agreement”), with JonesTrading Institutional Services LLC (the “Agent”), as follows:

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LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • January 6th, 2016 • Omeros Corp • Pharmaceutical preparations

THIS LOAN AND SECURITY AGREEMENT (as the same may from time to time be amended, modified, supplemented or restated, this “Agreement”) dated as of December 30, 2015 (the “Closing Date”) among OXFORD FINANCE LLC, a Delaware limited liability company (“Oxford”), as collateral agent (in such capacity, “Collateral Agent”), the Lenders listed on Schedule 2.1.1 hereof or otherwise a party hereto from time to time including Oxford in its capacity as a Lender and EAST WEST BANK, a California state-chartered bank (“EWB”) (each a “Lender” and collectively, the “Lenders”), and OMEROS CORPORATION, a Washington corporation (“Borrower”), provides the terms on which Lenders shall lend to Borrower and Borrower shall repay the Lenders. The parties agree as follows:

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