0001193125-13-272512 Sample Contracts

FIFTH AMENDMENT TO LEASE
Lease • June 26th, 2013 • Regulus Therapeutics Inc. • Pharmaceutical preparations

THIS FIFTH AMENDMENT TO LEASE (this “Amendment”) is entered into as of this 21st day of February, 2013 (“Effective Date”), by and between BMR-3545-3575 JOHN HOPKINS LP, a Delaware limited partnership (“Landlord,” formerly known as BMR-John Hopkins Court LLC), and REGULUS THERAPEUTICS INC., a Delaware corporation (“Tenant”).

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