0001193125-06-042873 Sample Contracts

VENTURE LOAN AND SECURITY AGREEMENT
Venture Loan and Security Agreement • March 1st, 2006 • Northstar Neuroscience, Inc. • Connecticut

This Venture Loan and Security Agreement (this “Agreement”) is made by and among Northstar Neuroscience, Inc., a Washington corporation (“Borrower”); Horizon Technology Funding Company LLC, a Delaware limited liability company (“Horizon”) and Oxford Finance Corporation (“Oxford” and collectively with Horizon, “Lenders”). Lenders and Borrower hereby agree as follows:

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NORTHSTAR NEUROSCIENCE, INC. INDEMNIFICATION AGREEMENT
Indemnification Agreement • March 1st, 2006 • Northstar Neuroscience, Inc. • Washington

This Indemnification Agreement (the “Agreement”) is entered into on , 2006, between Northstar Neuroscience, Inc., a Washington corporation (the “Company”), and , a director, officer, or both, of the Company and/or one or more of its subsidiaries (“Indemnitee”), for good and valuable consideration as set forth below.

FIRST AMENDMENT TO FOURTH AMENDED AND RESTATED INVESTORS’ RIGHTS AGREEMENT
Investors’ Rights Agreement • March 1st, 2006 • Northstar Neuroscience, Inc.

This First Amendment to Fourth Amended and Restated Investors’ Rights Agreement, dated effective as of December 30, 2005 (this “First Amendment”), amends that certain Fourth Amended and Restated Investors’ Rights Agreement, dated April 9, 2004 (the “Original Agreement”), by and among Northstar Neuroscience, Inc., a Washington corporation (the “Company”), and the shareholders listed on Exhibit A thereto (the “Shareholders”), and is entered into by and among the Company and those Shareholders whose consent is required to amend the Original Agreement pursuant to Sections 1.13 and 5.2 of the Original Agreement.

MANUFACTURING AGREEMENT
Manufacturing Agreement • March 1st, 2006 • Northstar Neuroscience, Inc. • Washington

THIS MANUFACTURING AGREEMENT (the “Agreement”) is entered this 8th day of April 2004 (the “Effective Date”) by and between NORTHSTAR NEUROSCIENCE, INC., a Washington corporation (“Northstar”) and Oscor, a Florida corporation (“Oscor”).

MANUFACTURING AGREEMENT
Manufacturing Agreement • March 1st, 2006 • Northstar Neuroscience, Inc. • Washington

THIS MANUFACTURING AGREEMENT (the “Agreement”) is entered this 30th day of August 2004 (the “Effective Date”) by and between NORTHSTAR NEUROSCIENCE, INC., a Washington corporation (“Northstar”) and AVAIL, a Delaware corporation (“AVAIL”).

NORTHSTAR NEUROSCIENCE, INC. FOURTH AMENDED AND RESTATED INVESTORS’ RIGHTS AGREEMENT
Investors’ Rights Agreement • March 1st, 2006 • Northstar Neuroscience, Inc. • Washington

This Fourth Amended and Restated Investors’ Rights Agreement (the “Agreement”) is made as of the 9th day of April 2004, by and among Northstar Neuroscience, Inc., a Washington corporation (the “Company”), Boston Scientific Corporation, a Delaware corporation (“BSX”), and the investors listed on Exhibit A hereto (BSX, together with the parties listed on Exhibit A, the “Investors,” and each individually, an “Investor”).

MANUFACTURING AGREEMENT
Manufacturing Agreement • March 1st, 2006 • Northstar Neuroscience, Inc. • Washington

THIS MANUFACTURING AGREEMENT (the “Agreement”) is entered this 9th day of April 2004 (the “Effective Date”) by and between NORTHSTAR NEUROSCIENCE, INC. a Washington corporation (“Northstar”) and Texcel, a Massachusetts corporation (“Texcel”).

FOURTH AND BATTERY OFFICE LEASE
Fourth and Battery Office Lease • March 1st, 2006 • Northstar Neuroscience, Inc. • Washington

THIS LEASE, made the 5th day of July 2000, by and between SELIG REAL ESTATE HOLDINGS EIGHT, a Washington general partnership, whose address is 1000 Second Avenue, Suite 1800, Seattle, Washington, 98104-1046, hereinafter referred to as “Lessor” and VERTIS NEUROSCIENCE INC., a Washington corporation, hereinafter referred to as “Lessee”.

MANUFACTURING AGREEMENT
Manufacturing Agreement • March 1st, 2006 • Northstar Neuroscience, Inc. • Washington

THIS MANUFACTURING AGREEMENT (the “Agreement”) is entered this 9th day of April 2004 (the “Effective Date”) by and between NORTHSTAR NEUROSCIENCE, INC. a Washington Corporation (“Northstar”) and SMTEK International, a Delaware company. (“SMTEK”).

FIRST AMENDMENT TO LEASE
Lease • March 1st, 2006 • Northstar Neuroscience, Inc.

THIS FIRST AMENDMENT TO LEASE (this “Amendment”) is entered into as of July 2, 2002, by and between SELIG REAL ESTATE HOLDINGS EIGHT, a Washington general partnership (“Lessor”) and VERTIS NEUROSCIENCE, INC., a Washington corporation (“Lessee”).

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