0001144204-16-129029 Sample Contracts

EXCLUSIVE LICENSE AND DISTRIBUTION AGREEMENT
Exclusive License and Distribution Agreement • October 24th, 2016 • Nuo Therapeutics, Inc. • Surgical & medical instruments & apparatus • Delaware

This EXCLUSIVE LICENSE AND DISTRIBUTION AGREEMENT (“Agreement”) is made and entered into as of May 5, 2016 (“Effective Date”), between NUO THERAPEUTICS, INC., a Delaware corporation, with principal office at 207A Perry Parkway, Suite 1, Gaithersburg, MD 20877 (“Nuo”), and BOYALIFE HONG KONG LTD., a China corporation, with its principal office at 800 Jiefang Road East, 14th Floor, Wuxi, China 214002 (“Boyalife”). Each of Nuo and Boyalife is hereinafter referred to as a “Party” and collectively the “Parties.”

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EXCLUSIVE LICENSE AND DISTRIBUTION AGREEMENT
Exclusive License and Distribution Agreement • October 24th, 2016 • Nuo Therapeutics, Inc. • Surgical & medical instruments & apparatus • New York

This Exclusive License And Distribution Agreement (“Agreement”) is made and entered into as of December 31, 2014 (“Effective Date”), between Nuo therapeutics, Inc., (formerly Cytomedix Inc.) a Delaware corporation, with principal office at 207 Perry Parkway, Suite 1, Gaithersburg, MD 20877 (“Nuo”), and ROHTO Pharmaceutical Co., Ltd., a Japanese company, with its principal office at 1-8-1 Tatsumi-nishi, Ikuno-ku, Osaka 544-8666, Japan (“Rohto”). Each of Nuo and Rohto is hereinafter referred to as a “Party” and collectively the “Parties.”

AMENDMENT No. 5 TO LICENSING AND DISTRIBUTION AGREEMENT
Licensing and Distribution Agreement • October 24th, 2016 • Nuo Therapeutics, Inc. • Surgical & medical instruments & apparatus

This Amendment No. 5 to LICENSING AND DISTRIBUTION AGREEMENT (this “Amendment No. 5”) is dated as of December 31, 2014 by and between Nuo Therapeutics, Inc. (formerly Cytomedix Inc.), a Delaware corporation, with principal office at 207 Perry Parkway, Suite 1, Gaithersburg, MD 20877 (“Nuo” or “Cytomedix”) and Millennia Holdings, Inc., a California cooperation, with principal office at 3731 Wilshire Blvd., Suite 900, Los Angeles, CA 90010 (“Millennia”). Capitalized terms used in this Amendment No. 5 shall have the meanings ascribed to them in the Agreement (as defined below).

COLLABORATION AGREEMENT
Collaboration Agreement • October 24th, 2016 • Nuo Therapeutics, Inc. • Surgical & medical instruments & apparatus • Maryland

THIS COLLABORATION AGREEMENT (the “Agreement”), is entered into as of March 22, 2016 (the “Signing Date”) by and between Restorix Health, Inc. (“Restorix” ), a Nevada corporation, with its principal offices at 455 Hamilton Avenue, White Plains, NY 10601, and Nuo Therapeutics, Inc. (“Nuo”), a Delaware corporation, with its principal offices at 207A Perry Parkway, Suite 1, Gaithersburg, Maryland 20877. Restorix and Nuo may at times be referred to herein individually as a “Party” or collectively as the “Parties.”

October 20, 2016
Letter Agreement • October 24th, 2016 • Nuo Therapeutics, Inc. • Surgical & medical instruments & apparatus • Delaware

This letter agreement (“Agreement”) sets forth the agreement between Arthrex, Inc. (“Arthrex”), Deerfield SS, LLC (“Deerfield”) and Nuo Therapeutics, Inc. (“Nuo”), collectively the (“parties”), with respect to the sale of certain Nuo assets to Arthrex and the resolution of outstanding issues between the parties. The parties have agreed to the terms and conditions set forth in this Agreement. Accordingly, Arthrex, Nuo and Deerfield hereby agree as follows:

BACKSTOP COMMITMENT AGREEMENT
Backstop Commitment Agreement • October 24th, 2016 • Nuo Therapeutics, Inc. • Surgical & medical instruments & apparatus • Delaware

This Backstop Commitment Agreement, dated on and as of April 22, 2016 (this “Agreement”), is made by and among NUO THERAPEUTICS, INC., a Delaware corporation and debtor and debtor-in-possession under Chapter 11 of the United States Bankruptcy Code (the “Company”), and _______________________, an individual (the “Backstop Purchaser”).

April 15, 2016
Nuo Therapeutics, Inc. • October 24th, 2016 • Surgical & medical instruments & apparatus • Maryland

As we have discussed, your last day of work with Nuo Therapeutics, Inc. (“Nuo Therapeutics” or the “Company”) was January 8, 2016. This letter agreement (“Agreement”) sets forth the terms of your separation from the Company. As this is a legal document, you are advised to consult with an attorney before signing it.

SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • October 24th, 2016 • Nuo Therapeutics, Inc. • Surgical & medical instruments & apparatus • Delaware

This Securities Purchase Agreement, dated on and as of April __, 2016 (this “Agreement”), is made by and among NUO THERAPEUTICS, INC., a Delaware corporation and debtor and debtor-in-possession under Chapter 11 of the United States Bankruptcy Code (the “Company”), the undersigned purchasers (each a “Purchaser” and collectively, the “Purchasers”) and each assignee of a Purchaser who becomes a party hereto.

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