0001104659-26-080949 Sample Contracts

ROYALTY NOTE PURCHASE AGREEMENT dated as of June 30, 2026 among MeiraGTx, LLC as Issuer, MEIRAGTX HOLDINGS PLC as Parent, THE OTHER OBLIGORS PARTY HERETO, THE PURCHASERS PARTY HERETO, and MAVERICK SA LLC as Purchaser Agent
Royalty Note Purchase Agreement • July 7th, 2026 • MeiraGTx Holdings PLC • Biological products, (no disgnostic substances) • New York

This Royalty Note Purchase Agreement (as the same may from time to time be amended, modified, supplemented or restated, this “Agreement”) is made and dated as of June 30, 2026 (the “Effective Date”) among the Purchasers listed on Schedule 1.1 hereof or otherwise a party hereto from time to time (each a “Purchaser” and collectively, the “Purchasers”), Maverick SA LLC, a Delaware limited liability company, as agent for the Purchasers (in such capacity, “Purchaser Agent”), MeiraGTx, LLC, a Delaware limited liability company (“Issuer”), MeiraGTx Holdings plc, an exempted company with limited liability incorporated under the laws of the Cayman Islands with registration number 336306 (“Parent”), and the other Obligors from time to time party hereto. The parties agree as follows:

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SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • July 7th, 2026 • MeiraGTx Holdings PLC • Biological products, (no disgnostic substances) • New York

This SECURITIES PURCHASE AGREEMENT (this “Agreement”) is made and entered into as of June 30, 2026 by and between (i) MeiraGTx Holdings plc, a Cayman Islands exempted company, with offices at 655 Third Avenue, Suite 1115, New York, NY 10017 (the “Company”), and (ii) TPC Investments Solutions II LP, a Delaware limited partnership, and TPC Investments Solutions Co-Invest II LP, a Delaware limited partnership (each, an “Investor” and collectively, the “Investors”).

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REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • July 7th, 2026 • MeiraGTx Holdings PLC • Biological products, (no disgnostic substances) • New York

This REGISTRATION RIGHTS AGREEMENT (this “Agreement”) is made and entered into as of June 30, 2026 by and between (i) MeiraGTx Holdings plc, a Cayman Islands exempted company, with offices at 655 Third Avenue, Suite 1115, New York, NY 10017 (the “Company”), and (ii) TPC Investments Solutions II LP, a Delaware limited partnership, and TPC Investments Solutions Co-Invest II LP, a Delaware limited partnership (each, an “Investor” and collectively, the “Investors”) in connection with that certain Securities Purchase Agreement, by and between the Company and the Investors, dated as of even date herewith (the “Investment Agreement”). Capitalized terms used herein have the respective meanings ascribed thereto in the Investment Agreement unless otherwise defined herein.

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