0001104659-07-072019 Sample Contracts

SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • September 28th, 2007 • Senesco Technologies Inc • Services-commercial physical & biological research • New Jersey

THIS SECURITIES PURCHASE AGREEMENT (this “Agreement”), dated as of August 1, 2007, by and among SENESCO TECHNOLOGIES, INC., a Delaware corporation (the “Company”), and the Buyers listed on Schedule I attached hereto (individually, a “Buyer” or collectively “Buyers”).

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SENESCO TECHNOLOGIES, INC. INDEMNIFICATION AGREEMENT
Indemnification Agreement • September 28th, 2007 • Senesco Technologies Inc • Services-commercial physical & biological research • New Jersey

This Indemnification Agreement (“Agreement”) is made as of January 16, 2007 by and between Senesco Technologies, Inc., a Delaware corporation (the “Company”), and Jack Van Hulst (“Indemnitee”).

REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • September 28th, 2007 • Senesco Technologies Inc • Services-commercial physical & biological research • New Jersey
SECURITY AGREEMENT
Security Agreement • September 28th, 2007 • Senesco Technologies Inc • Services-commercial physical & biological research • New Jersey

THIS SECURITY AGREEMENT (the “Agreement”), is entered into and made effective as of September 21, 2007, by and between SENESCO TECHNOLOGIES, INC., a Delaware corporation with its principal place of business located at 303 George Street, Suite 420, New Brunswick, NJ 08901 (the “Parent”), and the each subsidiary of the Parent listed on Schedule I attached hereto (each a “Subsidiary,” and collectively and together with the Parent, the “Company”), in favor of the BUYER(S) (the “Secured Party”) listed on Schedule I attached to the Securities Purchase Agreement (the “Securities Purchase Agreement”) dated the date hereof between the Company and the Secured Party.

SENESCO TECHNOLOGIES, INC. SECURED CONVERTIBLE DEBENTURE
Senesco Technologies Inc • September 28th, 2007 • Services-commercial physical & biological research

FOR VALUE RECEIVED, SENESCO TECHNOLOGIES, INC., a Delaware corporation (the “Company”), hereby promises to pay to the order of YA GLOBAL INVESTMENTS, L.P. or its registered assigns (the “Holder”) the amount set out above as the Original Principal Amount (as reduced pursuant to the terms hereof pursuant to redemption, conversion or otherwise, the “Principal”) when due, whether upon the Maturity Date (as defined below), acceleration, redemption or otherwise (in each case in accordance with the terms hereof) and to pay interest (“Interest”) on any outstanding Principal at the applicable Interest Rate from the date set out above as the Issuance Date (the “Issuance Date”) until the same becomes due and payable, whether upon an Interest Date (as defined below), the Maturity Date, or acceleration, conversion, redemption or otherwise (in each case in accordance with the terms hereof). This Secured Convertible Debenture (including all Secured Convertible Debentures issued in exchange, transfer

April 2, 2007
Senesco Technologies Inc • September 28th, 2007 • Services-commercial physical & biological research
INSERT H.C. WAINWRIGHT LETTERHEAD]
Senesco Technologies Inc • September 28th, 2007 • Services-commercial physical & biological research

Mr. Bruce C. Galton President and Chief Executive Officer Senesco Technologies, Inc. 303 George Street Suite 420 New Brunswick, NJ 08901

Re: Amendment #5 to Consulting Agreement of July 12, 1999
Senesco Technologies Inc • September 28th, 2007 • Services-commercial physical & biological research

This will modify paragraph 11 of your Consulting Agreement with Senesco dated July 12, 1999, as modified. Effective immediately, the term of the Consulting Agreement will be extended for an additional 2 year term through June 30, 2009. All other terms of the Agreement remain unchanged.

August 1, 2007
Senesco Technologies Inc • September 28th, 2007 • Services-commercial physical & biological research

Ms. Judy Brown, Contracts Manager Office of Research University of Waterloo 200 University Avenue West Waterloo, Ontario, Canada N2L 3G1

REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • September 28th, 2007 • Senesco Technologies Inc • Services-commercial physical & biological research • New Jersey
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