0001104659-03-013010 Sample Contracts

SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • June 25th, 2003 • Supergen Inc • Pharmaceutical preparations • New York

SECURITIES PURCHASE AGREEMENT (the “Agreement”), dated as of June 24, 2003 by and among SuperGen, Inc., a Delaware corporation, with headquarters located at 4140 Dublin Boulevard, Suite 200, Dublin, California 94568 (the “Company”), and the investors listed on the Schedule of Buyers attached hereto (individually, a “Buyer” and collectively, the “Buyers”).

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AMENDED AND RESTATED SECURITIES ACCOUNT CONTROL AGREEMENT
Securities Account Control Agreement • June 25th, 2003 • Supergen Inc • Pharmaceutical preparations • New York

AMENDED AND RESTATED SECURITIES ACCOUNT CONTROL AGREEMENT (the “Agreement”), dated as of June 24, 2003, among SuperGen, Inc., a Delaware company (the “Company”), the secured parties set forth on the signature pages hereof (each, a “Secured Party”, and collectively, the “Secured Parties”), and Mellon Investor Services LLC, a New Jersey limited liability company, as Custodian.

CONVERSION AND AMENDMENT AGREEMENT
Conversion and Amendment Agreement • June 25th, 2003 • Supergen Inc • Pharmaceutical preparations • New York

CONVERSION AND AMENDMENT AGREEMENT (the “Agreement”), dated as of June 24, 2003, by and between SuperGen, Inc., a Delaware corporation, with headquarters located at 4140 Dublin Boulevard, Suite 200, Dublin, California 94568 (the “Company”), and (the “Investor”).

TRANSFER AGENT INSTRUCTIONS SUPERGEN, INC.
Transfer Agent Instructions • June 25th, 2003 • Supergen Inc • Pharmaceutical preparations

Reference is made to that certain Securities Purchase Agreement, dated as of date hereof (the “Agreement”), by and among SuperGen, Inc., a Delaware corporation (the “Company”), and the investors named on the Schedule of Buyers attached thereto (collectively, the “Holders”), pursuant to which the Company is issuing to the Holders senior convertible notes (the “Notes”), which are convertible into shares of common stock of the Company, par value $.001 per share (the “Common Stock”).

AMENDED AND RESTATED PLEDGE AGREEMENT
Pledge Agreement • June 25th, 2003 • Supergen Inc • Pharmaceutical preparations • New York

AMENDED AND RESTATED PLEDGE AGREEMENT (this “Agreement”), dated as of June 24, 2003, made by SuperGen, Inc., a Delaware corporation (the “Pledgor”), in favor of the investors set forth on the Collateral Schedule attached hereto, each with respect to the collateral pledged to it hereunder (each, a “Pledgee”, and collectively, the “Pledgees”).

REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • June 25th, 2003 • Supergen Inc • Pharmaceutical preparations • New York

REGISTRATION RIGHTS AGREEMENT (this “Agreement”), dated as of June 24, 2003, by and among SuperGen, Inc., a Delaware corporation, with headquarters located at 4140 Dublin Boulevard. Suite 200, Dublin, California 94568 (the “Company”), and the investors listed on the Schedule of Buyers attached hereto (each, a “Buyer” and collectively, the “Buyers”).

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