0001070081-19-000057 Sample Contracts

AMENDMENT NO.2 TO CREDIT AND SECURITY AGREEMENT
Credit and Security Agreement • October 30th, 2019 • PTC Therapeutics, Inc. • Pharmaceutical preparations • New York

This AMENDMENT NO. 2 TO CREDIT AND SECURITY AGREEMENT (this “Agreement”) is made as of this 7th day of August, 2019, by and among PTC Therapeutics, INC., a Delaware corporation (“Borrower”), MIDCAP FINANCIAL TRUST, as Agent (in such capacity, together with its successors and assigns, “Agent”) and the financial institutions or other entities from time to time parties to the Credit Agreement referenced below, each as a Lender.

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LEASE AGREEMENT BRISTOL-MYERS SQUIBB COMPANY (LANDLORD) TO PTC THERAPEUTICS, INC. (TENANT) Effective Date: August 3, 2019
Lease Agreement • October 30th, 2019 • PTC Therapeutics, Inc. • Pharmaceutical preparations • New Jersey
OMNIBUS AMENDMENT NO. 5 AND JOINDER TO CREDIT AND SECURITY AGREEMENT AND AMENDMENT AND JOINDER TO PLEDGE AGREEMENT
Credit and Security Agreement • October 30th, 2019 • PTC Therapeutics, Inc. • Pharmaceutical preparations • New York

This OMNIBUS AMENDMENT NO. 5 AND JOINDER TO CREDIT AND SECURITY AGREEMENT AND AMENDMENT AND JOINDER TO PLEDGE AGREEMENT, dated as of October 1, 2019 (this “Agreement”), is entered into by and among PTC THERAPEUTICS HOLDINGS, INC., a Delaware corporation (“PTC Holdings”), PTC THERAPEUTICS GT INC., a Delaware corporation, (“PTC GT”), PTC RLN LLC, a Delaware limited liability company (“PTC RLN”), PTC FRDA LLC, a Delaware limited liability company (“PTC FRDA”), PTC AS LLC, a Delaware limited liability company (“PTC AS”, and together with PTC Holdings, PTC GT, PTC RLN and PTC FRDA, individually, each a “New Borrower” and collectively, the “New Borrowers”), PTC THERAPEUTICS, INC., a Delaware corporation (the “Original Borrower”, and the Original Borrower together with the New Borrowers, collectively, the “Borrowers”), MIDCAP FINANCIAL TRUST, as Agent (in such capacity, together with its successors and assigns, “Agent”), and the financial institutions or other entities from time to time parti

AMENDMENT NO. 4 TO CREDIT AND SECURITY AGREEMENT
Credit and Security Agreement • October 30th, 2019 • PTC Therapeutics, Inc. • Pharmaceutical preparations • New York

This AMENDMENT NO. 4 TO CREDIT AND SECURITY AGREEMENT, dated as of September 17, 2019 (this “Agreement”), is entered into by and among PTC THERAPEUTICS, INC., a Delaware corporation (the “Borrower”), MIDCAP FINANCIAL TRUST, as Agent (in such capacity, together with its successors and assigns, “Agent”), and the financial institutions or other entities from time to time parties to the Credit Agreement referenced below, each as a Lender.

AMENDMENT NO. 3 TO CREDIT AND SECURITY AGREEMENT
Credit and Security Agreement • October 30th, 2019 • PTC Therapeutics, Inc. • Pharmaceutical preparations • New York

This AMENDMENT NO. 3 TO CREDIT AND SECURITY AGREEMENT, dated as of August 29, 2019 (this “Agreement”), is entered into by and among PTC THERAPEUTICS, INC., a Delaware corporation ( “Borrower”), MIDCAP FINANCIAL TRUST, as Agent (in such capacity, together with its successors and assigns, “Agent”), and the financial institutions or other entities from time to time parties to the Credit Agreement referenced below, each as a Lender.

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