0001047469-15-002551 Sample Contracts

JAGUAR ANIMAL HEALTH, INC. FORM OF COMMON STOCK WARRANT
Jaguar Animal Health, Inc. • March 20th, 2015 • Pharmaceutical preparations • Delaware

Holder is an “Accredited Investor” as that term is defined in Regulation D promulgated by the Securities and Exchange Commission. The term “Accredited Investor” under Regulation D refers to:

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Contract
Jaguar Animal Health, Inc. • March 20th, 2015 • Pharmaceutical preparations • New York

THIS WARRANT AND ANY COMMON STOCK ISSUED UPON THE EXERCISE OF THIS WARRANT HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR APPLICABLE STATE SECURITIES LAWS, AND MAY NOT BE OFFERED, SOLD, OR OTHERWISE TRANSFERRED, PLEDGED OR HYPOTHECATED IN THE ABSENCE OF SUCH REGISTRATION OR AN APPLICABLE EXEMPTION THEREFROM, AS EVIDENCED BY A LEGAL OPINION OF COUNSEL REASONABLY SATISFACTORY TO THE COMPANY TO SUCH EFFECT. NOTWITHSTANDING THE FOREGOING, THIS WARRANT AND THE COMMON STOCK ISSUABLE UPON EXERCISE OF THIS WARRANT MAY BE PLEDGED IN CONNECTION WITH A BONA FIDE MARGIN ACCOUNT OR OTHER LOAN OR FINANCING ARRANGEMENT SECURED BY SUCH SECURITIES.

FORM OF CONVERTIBLE NOTE AND WARRANT PURCHASE AGREEMENT
Convertible Note and Warrant Purchase Agreement • March 20th, 2015 • Jaguar Animal Health, Inc. • Pharmaceutical preparations • Delaware

THIS CONVERTIBLE NOTE AND WARRANT PURCHASE AGREEMENT (the “Agreement”) is dated for references purposes as of December 23, 2014 (the “Effective Date”), by and between Jaguar Animal Health, Inc., a Delaware corporation (the “Company”) and the investor whose name and signature are set forth on the signature page to this Agreement (the “Investor”).

AMENDMENT NO. 1 TO AMENDED AND RESTATED LICENSE AGREEMENT
License Agreement • March 20th, 2015 • Jaguar Animal Health, Inc. • Pharmaceutical preparations • Napo

THIS AMENDMENT NO. 1 TO AMENDED AND RESTATED LICENSE AGREEMENT (this “Amendment”), dated as of January 27, 2015 (the “Amendment Effective Date”) is entered into by and between NAPO PHARMACEUTICALS, INC., a Delaware corporation, with offices at 185 Berry Street, Suite 1300, San Francisco, California 94107 (“Napo”), and Jaguar Animal Health, Inc., a Delaware corporation, with offices at 185 Berry Street, Suite 1300, San Francisco, California 94107 (“JAH”). Napo and JAH are sometimes referred to herein individual as a “Party” and collectively as the “Parties.”

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