0001021408-03-005105 Sample Contracts

FOURTH AMENDMENT TO LEASE
Lease • March 27th, 2003 • Napro Biotherapeutics Inc • Medicinal chemicals & botanical products

THIS FOURTH AMENDMENT TO LEASE (“Fourth Amendment”), dated as of this ____ day of ___________, 2003, by and between NAPRO BIOTHERAPEUTICS, INC., a Colorado corporation (“Tenant”) and (i) GUNBARREL FACILITY L.L.C., a Colorado limited liability company (“Gunbarrel”), and (ii) MEYERS LAND & CATTLE COMPANY, a Colorado corporation (“Meyers”)(Gunbarrel and Meyers are collectively referred to herein as “Landlord”).

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ASSET PURCHASE AGREEMENT BETWEEN NAPRO BIOTHERAPEUTICS, INC. AND PANGENE CORPORATION DECEMBER 31, 2002
Asset Purchase Agreement • March 27th, 2003 • Napro Biotherapeutics Inc • Medicinal chemicals & botanical products • New York

This Asset Purchase Agreement (this “Agreement”) is entered into as of December 31, 2002, by and between NaPro BioTherapeutics, Inc., a Delaware corporation (“Buyer”), and Pangene Corporation, a California corporation (“Seller”). Each of Buyer and Seller are sometimes referred to herein individually as a “Party” and collectively as the “Parties.”

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