0000950136-07-004544 Sample Contracts

SECOND AMENDMENT TO LEASE
Lease • June 28th, 2007 • Vion Pharmaceuticals Inc • Biological products, (no disgnostic substances) • Connecticut

THIS SECOND AMENDMENT TO LEASE is made and entered into as of June 27, 2007 by and between SCIENCE PARK DEVELOPMENT CORPORATION, a Connecticut corporation having its office at 25 Science Park, Suite 103, New Haven, Connecticut 06511 (the “Landlord”), and VION PHARMACEUTICALS, INC., a Delaware corporation having its office at 4 Science Park, New Haven, Connecticut 06511, (the “Tenant”) in modification of that certain lease between the Landlord and the Tenant dated as of November 1, 2001 (the “Original Lease”) as amended by a First Amendment to Lease dated as of January 26, 2005 (the “Original Lease” as so amended, the “Lease”).

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