0000912057-14-000451 Sample Contracts

AGREEMENT FOR THE JOINT OWNERSHIP AND LICENSING OF EXPLOITATION RIGHTS
Agreement for the Joint Ownership and Licensing of Exploitation Rights • November 19th, 2014 • TiGenix NV • Pharmaceutical preparations

Of the one part, the Consejo Superior de Investigaciones Científicas (hereinafter, “CSIC”), with VAT no. Q-2818002-D, and in the name and on behalf of the same, Mr. Rafael Rodrigo Montero, President of such Body, with its headquarters at calle Serrano no. 117, 28006 - Madrid, who has sufficient powers to enter into this agreement by virtue of the provisions contained in the Bylaws of the mentioned body, approved by Royal Decree 1730/2007, of December 21st (Spanish State Gazette of January 14th, 2008), which powers have not been revoked or varied;

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AMENDMENT TO THE AGREEMENT FOR THE ASSIGNMENT OF RIGHTS TO EXPLOIT IP BETWEEN THE UNIVERSIDAD AUTONOMA DE MADRID AND CELLERIX, S.L., OF NOVEMBER 3rd, 2004
The Agreement • November 19th, 2014 • TiGenix NV • Pharmaceutical preparations

Of the one part, the Excellent Mr. Ángel Gabilondo Pujol, Magnificent Rector of the Universidad Autónoma de Madrid, located at the Ciudad Universitaria de Cantoblanco, C/ Einstein, 3, 28049 Madrid, in the name and on behalf of said University, and pursuant to the powers conferred to him by virtue of his office;

Agreement for the Manufacturing of ChondroCelect® Between TIGENIX B.V. and TIGENIX NV and PHARMACELL B.V.
Agreement • November 19th, 2014 • TiGenix NV • Pharmaceutical preparations

[***] Certain information has been omitted and filed separately with the Commission. Confidential treatment has been requested with respect to omitted portions.

AGREEMENT FOR THE JOINT OWNERSHIP AND LICENSING OF EXPLOITATION RIGHTS BETWEEN
Agreement • November 19th, 2014 • TiGenix NV • Pharmaceutical preparations

Of the one part the Consejo Superior de Investigaciones Cientificas (hereinafter, “CSIC”), with VAT no. Q-2818002-D, and in the name and on behalf of the same, Mr. Rafael Rodrigo Montero, President of such Body, with its headquarters at calle Serrano no. 117, 28006 — Madrid and constituted according to Royal Decree 1730/2007, of December 21st (Spanish State Gazette of January 14th, 2008), who has sufficient powers to enter into this agreement by virtue of article 11.2e) and i) of the Bylaws of the CSIC, approved by Royal Decree 1730/2007, and according to Royal Decree 663/2008 by which he is appointed President of the CSIC

ASSIGNMENT OF EXPLOITATION RIGHTS
Assignment of Exploitation Rights • November 19th, 2014 • TiGenix NV • Pharmaceutical preparations • Madrid

Ms María Jesús Matilla Quiza, Vice Rector of Research, Universidad Autónoma de Madrid (“UAM”), acting for and on behalf of UAM, with address at calle Einstein 13 2ª pta Pabellón C 28049 Madrid, by virtue of the powers in which she is vested by delegation of the powers of the Rector under the decision dated 4 June 2002 (published in BOCM, the Madrid regional government gazette, No 164, 12 July 2002);

LEASE AGREEMENT FOR OFFICES AND PARKING SPACES IN CALLE MARCONI 1, TRES CANTOS (MADRID)
Lease Agreement • November 19th, 2014 • TiGenix NV • Pharmaceutical preparations

AS ONE PARTY, MR JOSÉ LUIS GÓMEZ RUIZ, of legal age, with national ID no. ##.###.###-#and MR ÁLVARO GARCÍA DE LA RASILLA GORTÁZAR, of legal age with national ID no. ##.###.###-# both domiciled for professional purposes in Boadilla del Monte, Avenida de Cantabria (unnumbered), Edificio Arrecife, planta baja (Arrefice Building, ground floor) (Ciudad Grupo Santander);

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