November 13, 2003 Ron Wooten c/o Quintiles Transnational Corp. 4709 Creekstone Drive Riverbirch Building, Suite 300 Durham, NC 27703 Re: Amendment to Executive Employment Agreement Dear Ron:

(Quintiles Transnational Corp. Logo)		Quintiles Transnational Corp, Post Office Box 13979 Research Triangle Park, NC 27709-3979 ▇▇▇ ▇▇▇ ▇▇▇▇ / Fax ▇▇▇ ▇▇▇ ▇▇▇▇		EXHIBIT 10.19
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November 13, 2003

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c/o Quintiles Transnational Corp.
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Re: Amendment to Executive Employment Agreement

Dear ▇▇▇:

Reference is made to the amendment to your Executive Employment Agreement dated as of November 12, 2003 (the “Amendment”). This will confirm our agreement that in lieu of the calculation of the 36 monthly severance payments in the manner specified in paragraph 4 of the Amendment, each such monthly payment will instead equal your monthly rate of base salary in effect at the time of your termination of employment, multiplied by 1.55.

All other terms of the Executive Employment Agreement, as amended by the Amendment, are unaffected by this letter, including the conditions that must be met to receive or retain severance benefits.

Please confirm that this conforms to your understanding of our agreement by signing below.

Sincerely yours,

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Executive Vice President, Global Human Resources

Agreed to and Accepted by:

		11/14/03
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