CASI Pharmaceuticals, Inc. Sample Contracts

OPEN MARKET SALE AGREEMENTSM
Open Market Sale Agreement • December 20th, 2024 • CASI Pharmaceuticals, Inc. • Pharmaceutical preparations • New York
INDEMNIFICATION AGREEMENT
Indemnification Agreement • January 31st, 2023 • CASI Pharmaceuticals Holdings, Inc.

This INDEMNIFICATION AGREEMENT (this “Agreement”) is made as of by and between CASI Pharmaceuticals, Inc., an exempted company incorporated and existing under the laws of the Cayman Islands (the “Company”), and , an individual (Passport/ID Card No. ) (the “Indemnitee”).

Guarantee Contract
Guarantee Contract • March 28th, 2024 • CASI Pharmaceuticals, Inc. • Pharmaceutical preparations • Macau

This Guarantee Contract (this “Contract”) is entered into this 14th day of December 2023 in Huishan District, Wuxi City, Jiangsu Province, China, by and among the following parties:

SUBSCRIPTION AGREEMENT
Subscription Agreement • August 16th, 2024 • CASI Pharmaceuticals, Inc. • Pharmaceutical preparations • New York

The Company, on the one hand, and the Purchaser, on the other hand, are hereinafter each referred to as a “Party” and collectively as the “Parties”.

Contract
Exclusive Distribution Agreement • April 26th, 2023 • CASI Pharmaceuticals, Inc. • Pharmaceutical preparations

Certain confidential information contained in this document, marked by brackets and *** asterisk, has been omitted pursuant to Item 601(b)(10)(iv) of Regulation S-K, because it (i) is not material and (ii) would be competitively harmful if publicly disclosed.

CASI PHARMACEUTICALS, INC. CONVERTIBLE PROMISSORY NOTE PURCHASE AGREEMENT
Convertible Promissory Note Purchase Agreement • May 15th, 2026 • CASI Pharmaceuticals, Inc. • Pharmaceutical preparations • New York

THIS CONVERTIBLE PROMISSORY NOTE PURCHASE AGREEMENT (this “Purchase Agreement”) is dated as of December 9, 2025 (the “Effective Date”), by and between CASI Pharmaceuticals, Inc., an exempted company with limited liability incorporated under the laws of the Cayman Islands (the “Company”), and ETP Global III Fund LP, a Delaware limited partnership (the “Purchaser”).

Contract
Exclusive Distribution Agreement • March 28th, 2024 • CASI Pharmaceuticals, Inc. • Pharmaceutical preparations

Information in this exhibit identified by brackets and *** has been redacted because it is not material and is the type that the Company treats as private or confidential

Equity and Asset Transfer Agreement By and Among CASI Pharmaceuticals, Inc. Kaixin Pharmaceuticals Inc. CASI Pharmaceuticals (China) Co., Ltd. AND CASI Pharmaceuticals (Wuxi) Co., Ltd. May 9, 2025
Equity and Asset Transfer Agreement • May 15th, 2026 • CASI Pharmaceuticals, Inc. • Pharmaceutical preparations

This Equity and Asset Transfer Agreement (this “Agreement”) is entered into on May 9, 2025 (the “Execution Date”) in the People’s Republic of China (the “PRC”) by and among:

Capital Reduction Agreement CASI Pharmaceuticals (Wuxi) Co., Ltd. Wuxi, China December 14, 2023
Capital Reduction Agreement • March 28th, 2024 • CASI Pharmaceuticals, Inc. • Pharmaceutical preparations

This Capital Reduction Agreement of CASI Pharmaceuticals (Wuxi) Co., Ltd. (this “Agreement”) is entered into this 14th day of December 2023 (“Signing Date”) in Huishan District, Wuxi City, Jiangsu Province, China, by and among the following parties:

AMENDMENT NO. 1 TO Assignment AGREEMENT IN RESPECT OF THE TERRITORY OF CHINA
Assignment Agreement • March 28th, 2024 • CASI Pharmaceuticals, Inc. • Pharmaceutical preparations

This Amendment No. 1 (“Amendment 1”) is hereby entered into as of July 31, 2023 (“Amendment 1 Effective Date”) by and between Acrotech Biopharma Inc. (“Acrotech”), having a principal place of business at 279 Princeton Hightstown Road, Suite 103, East Windsor, New Jersey 08520, and CASI Pharmaceuticals, Inc. (“CASI”), having a principal place of business at 1701-1702, China Central Office, Tower 1, No. 81 Jianguo Road, Chaoyang District, Beijing 100025 People’s Republic of China (collectively, the “Parties”).

SUBSCRIPTION AND PURCHASE AGREEMENT
Subscription and Purchase Agreement • August 16th, 2024 • CASI Pharmaceuticals, Inc. • Pharmaceutical preparations • New York

The Company, on the one hand, and the Purchaser, on the other hand, are hereinafter each referred to as a “Party” and collectively as the “Parties”.

SUBSCRIPTION AND PURCHASE AGREEMENT
Subscription and Purchase Agreement • August 16th, 2024 • CASI Pharmaceuticals, Inc. • Pharmaceutical preparations • New York

The Company, on the one hand, and each Purchaser, on the other hand, are hereinafter each referred to as a “Party” and collectively as the “Parties”.

1Information in this exhibit identified by brackets and *** has been redacted because it is not material and is the type that the Company treats as private or confidential
Assignment Agreement • March 28th, 2024 • CASI Pharmaceuticals, Inc. • Pharmaceutical preparations • Delaware
FOLOTYN SUPPLY AGREEMENT
Supply Agreement • March 28th, 2024 • CASI Pharmaceuticals, Inc. • Pharmaceutical preparations • New York

This FOLOTYN SUPPLY AGREEMENT (this “Agreement”), dated as of July 31, 2023 (the “Effective Date”), is made between Acrotech Biopharma Inc., a State of Delaware corporation (“Acrotech” or “Supplier”), with offices at 279 Princeton-Hightstown Road, Suite 103, East Windsor, NJ 08520, and CASI Pharmaceuticals, Inc., a Cayman corporation (“CASI” or “Buyer”), with offices at 1701-1702, China Central Office, Tower 1, No. 81 Jianguo Road, Chaoyang District, Beijing 100025 People’s Republic of China. Supplier and Buyer are referred to as the “Parties.”

SUPPLEMENTARY AGREEMENT TO THE EXCLUSIVE DISTRIBUTION AGREEMENT
Supplementary Agreement to the Exclusive Distribution Agreement • March 28th, 2024 • CASI Pharmaceuticals, Inc. • Pharmaceutical preparations

This Supplementary Agreement to the Exclusive Distribution Agreement (this “Supplementary Agreement”), is entered into as of 【28】February, 2024(“Effective Date”), by and between:

Equity Transfer Agreement
Equity Transfer Agreement • May 15th, 2026 • CASI Pharmaceuticals, Inc. • Pharmaceutical preparations

Party A: Wuxi Zhihe Daokang II Venture Capital Partnership (Limited Partnership) (hereinafter referred to as “Zhihe Daokang” or the “Transferor”), a limited partnership legally established and validly existing under the laws of the People’s Republic of China, with Unified Social Credit Code 91320205MA27GJLN83.

EXECUTION VERSION
Assignment of Rights Agreement • March 28th, 2024 • CASI Pharmaceuticals, Inc. • Pharmaceutical preparations

Information in this exhibit identified by brackets and *** has been redacted because it is not material and is the type that the Company treats as private or confidential

Form EMPLOYMENT AGREEMENT
Employment Agreement • January 31st, 2023 • CASI Pharmaceuticals Holdings, Inc.

This EMPLOYMENT AGREEMENT (“Agreement”) is made effective as of [*], by and between CASI PHARMACEUTICALS, INC., an exempted company incorporated and existing under the laws of the Cayman Islands (the “Company”), and [*] (the “Executive”).

Contract
Assignment Agreement • March 28th, 2024 • CASI Pharmaceuticals, Inc. • Pharmaceutical preparations • New York

Information in this exhibit identified by brackets and *** has been redacted because it is not material and is the type that the Company treats as private or confidential

Convertible Loan Agreement in respect of CASI Pharmaceuticals (Wuxi) Co., Ltd. by and among Wuxi Huicheng Yuanda Investment Partnership (Limited Partnership) on the one hand - and - CASI Pharmaceuticals (Wuxi) Co., Ltd. CASI Pharmaceuticals, Inc. CASI...
Convertible Loan Agreement • March 28th, 2024 • CASI Pharmaceuticals, Inc. • Pharmaceutical preparations

This Convertible Loan Agreement in respect of CASI Pharmaceuticals (Wuxi) Co., Ltd. (this “Agreement” or “Convertible Loan Agreement”) is entered into this 14th day of December 2023 (“Signing Date”) in Huishan District, Wuxi City, Jiangsu Province, China, by and among the following parties: