EXHIBIT 4.10 FORM OF INDENTURE TO BE ENTERED INTO BETWEEN THE COMPANY AND U.S. BANK NATIONAL ASSOCIATION SANTARUS, INC.Santarus Inc • May 12th, 2005 • Pharmaceutical preparations • New York
WARRANT TO PURCHASE SHARES OF COMMON STOCK OF SANTARUS, INC.Santarus Inc • February 4th, 2004 • Pharmaceutical preparations • California
COMMON STOCKUnderwriting Agreement • June 24th, 2004 • Santarus Inc • Pharmaceutical preparations • New York
RECITALSIndemnification Agreement • February 4th, 2004 • Santarus Inc • Pharmaceutical preparations • Delaware
COMMON STOCKStock Purchase Agreement • March 9th, 2004 • Santarus Inc • Pharmaceutical preparations • New York
Santarus, Inc. UNDERWRITING AGREEMENTUnderwriting Agreement • May 10th, 2013 • Santarus Inc • Pharmaceutical preparations • New York
EXHIBIT 10.16 EMPLOYMENT AGREEMENT THIS EMPLOYMENT AGREEMENT (this "Agreement") is entered into by and between Santarus, Inc., a Delaware corporation (the "Company"), and William C. Denby, III ("Executive"), and shall be effective as of the date on...Employment Agreement • March 9th, 2004 • Santarus Inc • Pharmaceutical preparations • California
CONFIDENTIALLicense Agreement • December 23rd, 2003 • Santarus Inc • New York
CONFIDENTIALLicense Agreement • March 9th, 2004 • Santarus Inc • Pharmaceutical preparations • New York
EXHIBIT 10.3 EMPLOYMENT AGREEMENT THIS EMPLOYMENT AGREEMENT (this "Agreement") is entered into by and between Santarus, Inc., a Delaware corporation (the "Company"), and C. Christine Simmons ("Executive"), and shall be effective as of July 27, 2004...Employment Agreement • August 13th, 2004 • Santarus Inc • Pharmaceutical preparations • California
andRights Agreement • November 17th, 2004 • Santarus Inc • Pharmaceutical preparations • Delaware
AMENDMENT NO. 1 TO AMENDED AND RESTATED INVESTORS' RIGHTS AGREEMENT' Rights Agreement • December 23rd, 2003 • Santarus Inc
SANTARUS, INC.Investors' Rights Agreement • December 23rd, 2003 • Santarus Inc • California
EXCLUSIVE LICENSE AGREEMENT BETWEEN THE UNIVERSITY OF MISSOURI AND SANTARUS, INC.Exclusive License Agreement • February 4th, 2004 • Santarus Inc • Pharmaceutical preparations • California
Exhibit 10.1 7,350,000 SHARES SANTARUS, INC. SHARES OF COMMON STOCK ($0.0001 PAR VALUE) PLACEMENT AGENT AGREEMENTAgent Agreement • August 17th, 2005 • Santarus Inc • Pharmaceutical preparations • New York
AMENDED AND RESTATED EMPLOYMENT AGREEMENTEmployment Agreement • May 6th, 2013 • Santarus Inc • Pharmaceutical preparations • California
THIS AMENDED AND RESTATED EMPLOYMENT AGREEMENT (this “Agreement”) is entered into by and between Santarus, Inc., a Delaware corporation (the “Company”), and Julie A. DeMeules (“Executive”), and shall be effective as of March 22, 2013.
EXHIBIT 4.9 FORM OF INDENTURE TO BE ENTERED INTO BETWEEN THE COMPANY AND U.S. BANK NATIONAL ASSOCIATION SANTARUS, INC.Santarus Inc • May 12th, 2005 • Pharmaceutical preparations • New York
EXHIBIT 10.8 OFFICE BUILDING LEASE Torrey View Associates LP, a California limited partnershipOffice Building Lease • December 23rd, 2003 • Santarus Inc • California
ORIGINALLY ISSUED ______________ AND REISSUED DECEMBER 11, 2003 THIS WARRANT AND THE SHARES OF CAPITAL STOCK ISSUED UPON ANY EXERCISE HEREOF HAVE NOT BEEN QUALIFIED WITH THE COMMISSIONER OF CORPORATIONS OF THE STATE OF CALIFORNIA AND THE ISSUANCE OF...Santarus Inc • February 4th, 2004 • Pharmaceutical preparations • California
WITNESSETH:Stock Purchase Agreement • December 23rd, 2003 • Santarus Inc • California
REGISTRATION RIGHTS AGREEMENTRegistration Rights Agreement • February 3rd, 2006 • Santarus Inc • Pharmaceutical preparations • New York
This REGISTRATION RIGHTS AGREEMENT (this “Agreement”), dated as of February 3, 2006, is by and between SANTARUS, INC. (the “Company”) and KINGSBRIDGE CAPITAL LIMITED (the “Investor”).
COMMON STOCK PURCHASE AGREEMENT by and between KINGSBRIDGE CAPITAL LIMITED and SANTARUS, INC. dated as of February 3, 2006Common Stock Purchase Agreement • February 3rd, 2006 • Santarus Inc • Pharmaceutical preparations • New York
This COMMON STOCK PURCHASE AGREEMENT (this “Agreement”) is entered into as of the 3rd day of February, 2006, by and between KINGSBRIDGE CAPITAL LIMITED, an entity organized and existing under the laws of the British Virgin Islands (the “Investor”) and SANTARUS, INC., a corporation organized and existing under the laws of the State of Delaware (the “Company”).
LOAN AND SECURITY AGREEMENTLoan and Security Agreement • August 1st, 2006 • Santarus Inc • Pharmaceutical preparations • California
This LOAN AND SECURITY AGREEMENT (this “Agreement”) is entered into as of July 28, 2006, by and between COMERICA BANK (“Bank”) and SANTARUS, INC. (“Borrower”).
RECITALSManufacturing and Supply Agreement • February 4th, 2004 • Santarus Inc • Pharmaceutical preparations
RECITALSManufacturing and Supply Agreement • December 23rd, 2003 • Santarus Inc
CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS DOCUMENT (INDICATED BY ASTERISKS) HAS BEEN OMITTED AND FILED SEPARATELY WITH THE SECURITIES AND EXCHANGE COMMISSION PURSUANT TO A REQUEST FOR CONFIDENTIAL TREATMENT UNDER 17 C.F.R. SECTIONS...Restriction and Registration Rights Agreement • December 23rd, 2003 • Santarus Inc • California
AMENDMENT TO THE AMENDED AND RESTATED EMPLOYMENT AGREEMENTEmployment Agreement • March 4th, 2011 • Santarus Inc • Pharmaceutical preparations
This AMENDMENT TO THE AMENDED AND RESTATED EMPLOYMENT AGREEMENT (the “Amendment”) is entered into by and between Santarus, Inc., a Delaware corporation (the “Company”), and Maria Bedoya-Toro (“Executive”), and shall be effective as of February 14, 2011.
Second Amended and Restated LIBOR Addendum to Amended and Restated Loan and Security AgreementLoan and Security Agreement • February 14th, 2012 • Santarus Inc • Pharmaceutical preparations
This Second Amended and Restated LIBOR Addendum to Amended and Restated Loan and Security Agreement (this “Addendum”) is entered into as of February 13, 2012 by and between COMERICA BANK (“Bank”) and SANTARUS, INC. (“Borrower”). This Addendum supplements the terms of the Amended and Restated Loan and Security Agreement (as amended from time to time, the “Loan Agreement”) dated as of July 11, 2008.
KILROY CENTRE DEL MAR OFFICE LEASEOffice Lease • October 10th, 2012 • Santarus Inc • Pharmaceutical preparations • California
This Office Lease (the “Lease”), dated as of the date set forth in Section 1 of the Summary of Basic Lease Information (the “Summary”), below, is made by and between KILROY REALTY, L.P., a Delaware limited partnership (“Landlord”), and SANTARUS, INC., a Delaware corporation (“Tenant”).
License Agreement Pharming Group N.V. and Pharming Intellectual Property b.v. and Santarus, Inc. September 10, 2010License Agreement • March 8th, 2011 • Santarus Inc • Pharmaceutical preparations • New York
This License Agreement (the “Agreement”) is made effective as of the 10th day of September, 2010 (the “Effective Date”) by and between Pharming Group N.V., a Dutch corporation having its principal place of business at Darwinweg 24, 2333 CR Leiden, The Netherlands, on behalf of itself and each of its Affiliates, including Pharming Intellectual Property B.V. and Pharming Technologies B.V. (“Pharming”) and Santarus, Inc., a Delaware corporation with its principal place of business at 3721 Valley Centre Drive, Suite 400, San Diego, California 92130 (“Santarus”). Pharming and Santarus are sometimes referred to herein individually as a “Party” and collectively as the “Parties.”
SETTLEMENT AND LICENSE AGREEMENTSettlement and License Agreement • May 8th, 2012 • Santarus Inc • Pharmaceutical preparations • California
This action for alleged patent infringement (the “Litigation”) has been brought by Plaintiff Depomed, Inc. (“Depomed”) against Defendants Lupin Pharmaceuticals, Inc. and Lupin Limited (collectively, “Lupin”) for alleged infringement of United States Patent Nos. 6,635,280, 6,340,475, and 6,488,962 (collectively the “Depomed Patents”). Depomed’s commencement of the Litigation was based on its receipt of notice from Lupin Limited that Lupin Limited had filed Abbreviated New Drug Application (“ANDA”) No. 91-664 with the United States Food and Drug Administration containing a certification pursuant to 21 U.S.C. § 355(j)(2)(A)(vii)(IV) directed to the Depomed Patents and seeking approval to market 500 mg and 1000 mg metformin tablets as a generic version of Glumetza®.
COMMERCIALIZATION AGREEMENTCommercialization Agreement • November 7th, 2011 • Santarus Inc • Pharmaceutical preparations • California
This COMMERCIALIZATION AGREEMENT (this “Agreement”) is made as of August 22, 2011 (the “Effective Date”), by and between Depomed, Inc., a California corporation (“Depomed”), and Santarus, Inc., a Delaware corporation (“Santarus”). Each of Depomed and Santarus is referred to herein individually as a “party” and collectively as the “parties.”
AMENDMENT TO LICENSE AGREEMENTLicense Agreement • March 8th, 2011 • Santarus Inc • Pharmaceutical preparations • California
THIS AMENDMENT TO LICENSE AGREEMENT, dated as of September 10, 2010 (the “Amendment”), is entered into among Biogen Idec MA Inc. (“Biogen Idec”), Covella Pharmaceuticals, Inc. (“Covella”) and Santarus, Inc. (“Santarus”) (hereinafter collectively, the “Parties”).
EXHIBIT 10.5 *** CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS DOCUMENT (INDICATED BY ASTERISKS) HAS BEEN OMITTED AND FILED SEPARATELY WITH THE SECURITIES AND EXCHANGE COMMISSION PURSUANT TO A REQUEST FOR CONFIDENTIAL TREATMENT UNDER 17 C.F.R....Omeprazole Supply Agreement • February 4th, 2004 • Santarus Inc • Pharmaceutical preparations
LICENSE AGREEMENT BY AND AMONG COWEN HEALTHCARE ROYALTY PARTNERS, L.P. AND SHORE THERAPEUTICS, INC. AND SANTARUS, INC. DATED DECEMBER 21, 2011License Agreement • March 5th, 2012 • Santarus Inc • Pharmaceutical preparations • New York
THIS LICENSE AGREEMENT (the “Agreement”) is made and entered into as of December 21, 2011 (the “Effective Date”), by and among COWEN HEALTHCARE ROYALTY PARTNERS, L.P., a Delaware limited partnership, having its principal place of business at 177 Broad Street, Suite 1101, Stamford, CT 06901 (“CHRP”), SHORE THERAPEUTICS, INC., a Delaware corporation, having its principal place of business at 177 Broad Street, Suite 1101, Stamford, CT 06901 (“Shore”) and SANTARUS, INC., a Delaware corporation, having its principal place of business at 3721 Valley Centre Drive, Suite 400, San Diego, California 92130 (“Santarus”). CHRP and Shore, on the one hand, and Santarus, on the other hand, are referred to individually as a “Party” and collectively as the “Parties.”
