Common use of Trade Date Clause in Contracts

Trade Date. June 1, 2022 Effective Date: The second Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 per share (Exchange symbol “CNMD”) Number of Warrants: 963,340. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.5275. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.79, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 Premium Payment Date: June 6, 2022 Exchange: New York Stock Exchange Related Exchange(s): All Exchanges

Trade Date. June 12, 2022 Effective Date: The second Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 per share (Exchange symbol “CNMD”) Number of Warrants: 963,340137,620. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.5275. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.79, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 1,800,000 Premium Payment Date: June 6, 2022 Exchange: New York Stock Exchange Related Exchange(s): All Exchanges

Trade Date. June 1February 5, 2022 2020 Effective Date: The second Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 per share (Exchange symbol “CNMDIART”) Number of Warrants: 963,340203,609. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.5275113.3400. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7957.83, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 1,162,500 Premium Payment Date: June 6February 7, 2022 2020 Exchange: New York Stock Exchange The NASDAQ Global Select Market Related Exchange(s): All Exchanges

Trade Date. June 1December 12, 2022 2016 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The Class A common stock of Company, par value USD 0.01 per share (Exchange symbol “CNMDWWE”) Number of Warrants: 963,3403,612,645. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.527531.8880. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7919.93, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 8,757,000 Premium Payment Date: June 6December 16, 2022 2016 Exchange: The New York Stock Exchange Related Exchange(s): All Exchanges

Trade Date. June 1January 25, 2022 2019 Effective Date: The second Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 per share (Exchange symbol “CNMD”) Number of Warrants: 963,34076,010. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.5275114.9225. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7969.6500, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 598,050.00 Premium Payment Date: June 6January 29, 2022 2019 Exchange: New York Stock Exchange NASDAQ Global Select Market Related Exchange(s): All Exchanges

Trade Date. June 1January 24, 2022 2019 Effective Date: The second Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 per share (Exchange symbol “CNMD”) Number of Warrants: 963,340506,736. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.5275114.9225. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7969.6500, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 3,987,000.00 Premium Payment Date: June 6January 29, 2022 2019 Exchange: New York Stock Exchange NASDAQ Global Select Market Related Exchange(s): All Exchanges

Trade Date. June 12, 2022 Effective Date: The second Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 per share (Exchange symbol “CNMD”) Number of Warrants: 963,34068,810. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.5275. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.79, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 900,000 Premium Payment Date: June 6, 2022 Exchange: New York Stock Exchange Related Exchange(s): All Exchanges

Trade Date. June 1December 12, 2022 2016 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The Class A common stock of Company, par value USD 0.01 per share (Exchange symbol “CNMDWWE”) Number of Warrants: 963,340802,810. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.527531.8880. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7919.93, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 1,946,000 Premium Payment Date: June 6December 16, 2022 2016 Exchange: The New York Stock Exchange Related Exchange(s): All Exchanges

Trade Date. June 119, 2022 2017 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 0.001 per share Share (Exchange symbol “CNMDNOW”) Number of Warrants: 963,340[ ]. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.5275203.40. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.79103.60, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 [ ] Premium Payment Date: June 622, 2022 2017 Exchange: The New York Stock Exchange Related Exchange(s): All Exchanges

Trade Date. June 1February 10, 2022 2015 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 per share Share (Exchange symbol “CNMDWMGI”) ). Number of Warrants: 963,340801,749. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.527540.0000. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7925.19, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to CompanyIssuer’s capitalization. Premium: USD 12,600,000 3,380,850.00 Premium Payment Date: June 6February 13, 2022 2015 Exchange: New York Stock Exchange The NASDAQ Global Select Market Related Exchange(s): All Exchanges

Trade Date. June 1May 18, 2022 2017 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 per share Share (Exchange symbol “CNMDAAWW”) Number of Warrants: 963,340142,430. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.5275. 92.20 Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7959.85, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 1,148,400.00 Premium Payment Date: June 6May 23, 2022 2017 Exchange: New York Stock Exchange The NASDAQ Global Select Market Related Exchange(s): All Exchanges

Trade Date. June 1May 11, 2022 2016 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 per share (Exchange symbol “CNMDKN”) Number of Warrants: 963,340610,584. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.527521.1050. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7913.06, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 2,548,125 Premium Payment Date: June 6May 13, 2022 2016 Exchange: The New York Stock Exchange Related Exchange(s): All Exchanges

Trade Date. June 1May 28, 2022 2015 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 per share Share (Exchange symbol “CNMDAAWW”) Number of Warrants: 963,340945,252. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.5275. 95.0130 Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7957.86, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 11,315,500 Premium Payment Date: June 63, 2022 2015 Exchange: New York Stock Exchange The NASDAQ Global Select Market Related Exchange(s): All Exchanges

Trade Date. June 1, 2022 Effective Date: The second Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 per share (Exchange symbol “CNMD”) Number of Warrants: 963,340481,670. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.5275. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.79, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 6,300,000 Premium Payment Date: June 6, 2022 Exchange: New York Stock Exchange Related Exchange(s): All Exchanges

Trade Date. June 1May 28, 2022 2015 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 per share Share (Exchange symbol “CNMDAAWW”) Number of Warrants: 963,3401,755,468. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.5275. 95.0130 Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7957.86, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 21,014,500 Premium Payment Date: June 63, 2022 2015 Exchange: New York Stock Exchange The NASDAQ Global Select Market Related Exchange(s): All Exchanges

Trade Date. June 18, 2022 2016 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 0.001 per share (Exchange symbol “CNMDNVRO”) Number of Warrants: 963,34070,045. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.5275127.2775. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7972.73, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 1,296,000 Premium Payment Date: June 613, 2022 2016 Exchange: The New York Stock Exchange Related Exchange(s): All Exchanges

Trade Date. June 1May 17, 2022 2017 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 0.001 per share (Exchange symbol “CNMDRP”) Number of Warrants: 963,3403,575,895. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.527557.5750. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7932.90, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 13,695,000.00 Premium Payment Date: June 6May 23, 2022 2017 Exchange: New York Stock Exchange The NASDAQ Global Select Market Related Exchange(s): All Exchanges

Trade Date. June 1February 17, 2022 2016 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Date, subject to Section 9(w). Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock shares of Company, without par value USD 0.01 per share (Exchange symbol “CNMDIVC”) Number of Warrants: 963,3406,245,117. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.527522.4175. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7914.22, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 8,580,000 Premium Payment Date: June 6February 23, 2022 2016 Exchange: The New York Stock Exchange Related Exchange(s): All Exchanges

Trade Date. June 1January 26, 2022 2017 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 per share (Exchange symbol “CNMDHZN”) Number of Warrants: 963,3401,761,760. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.527529.6000. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7918.76, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 7,554,800 Premium Payment Date: June 6February 1, 2022 2017 Exchange: The New York Stock Exchange Related Exchange(s): All Exchanges

Trade Date. June 1February 17, 2022 2016 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Date, subject to Section 9(w). Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock shares of Company, without par value USD 0.01 per share (Exchange symbol “CNMDIVC”) Number of Warrants: 963,3401,561,279. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.527522.4175. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7914.22, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 2,145,000 Premium Payment Date: June 6February 23, 2022 2016 Exchange: The New York Stock Exchange Related Exchange(s): All Exchanges

Trade Date. June 1May 11, 2022 2016 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 per share (Exchange symbol “CNMDKN”) Number of Warrants: 963,340366,350. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.527521.1050. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7913.06, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 1,528,875 Premium Payment Date: June 6May 13, 2022 2016 Exchange: The New York Stock Exchange Related Exchange(s): All Exchanges

Trade Date. June 1May 18, 2022 2017 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 per share Share (Exchange symbol “CNMDAAWW”) Number of Warrants: 963,340237,384. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.5275. 92.20 Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7959.85, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 1,914,000.00 Premium Payment Date: June 6May 23, 2022 2017 Exchange: New York Stock Exchange The NASDAQ Global Select Market Related Exchange(s): All Exchanges

Trade Date. June 1March 4, 2022 2016 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Date, subject to Section 9(w). Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock shares of Company, without par value USD 0.01 per share (Exchange symbol “CNMDIVC”) Number of Warrants: 963,340960,787. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.527522.4175. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7914.22, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 1,320,000 Premium Payment Date: June 6Xxxxx 0, 2022 Exchange0000 Xxxxxxxx: The New York Stock Exchange Related Exchange(s): All Exchanges

Trade Date. June 12, 2022 2015 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 per share (Exchange symbol “CNMDON”) Number of Warrants: 963,340[ ]. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.527525.9600. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7912.98, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 [ ] Premium Payment Date: June 68, 2022 2015 Exchange: New York Stock Exchange The NASDAQ Global Select Market Related Exchange(s): All Exchanges

Trade Date. June 1January 27, 2022 2017 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 per share (Exchange symbol “CNMDHZN”) Number of Warrants: 963,340180,180. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.527529.6000. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7919.44, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 772,650 Premium Payment Date: June 6February 1, 2022 2017 Exchange: The New York Stock Exchange Related Exchange(s): All Exchanges

Trade Date. June 17, 2022 2016 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 0.001 per share (Exchange symbol “CNMDNVRO”) Number of Warrants: 963,340466,965. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.5275127.2775. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7972.73, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 8,640,000 Premium Payment Date: June 613, 2022 2016 Exchange: The New York Stock Exchange Related Exchange(s): All Exchanges

Trade Date. June 1January 11, 2022 2017 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The Class A common stock of Company, par value USD 0.01 per share (Exchange symbol “CNMDWWE”) Number of Warrants: 963,34060,211. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.527531.8880. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7918.99, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 145,950 Premium Payment Date: June 6January 17, 2022 2017 Exchange: The New York Stock Exchange Related Exchange(s): All Exchanges

Trade Date. June 1May 18, 2022 2017 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 per share Share (Exchange symbol “CNMDAAWW”) Number of Warrants: 963,34094,954. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.5275. 92.20 Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7959.85, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 765,600.00 Premium Payment Date: June 6May 23, 2022 2017 Exchange: New York Stock Exchange The NASDAQ Global Select Market Related Exchange(s): All Exchanges

Trade Date. June 1January 11, 2022 2017 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The Class A common stock of Company, par value USD 0.01 per share (Exchange symbol “CNMDWWE”) Number of Warrants: 963,340270,948. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.527531.8880. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7918.99, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 656,775 Premium Payment Date: June 6January 17, 2022 2017 Exchange: The New York Stock Exchange Related Exchange(s): All Exchanges

Trade Date. June 1February 9, 2022 2015 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 per share Share (Exchange symbol “CNMDWMGI”) ). Number of Warrants: 963,3405,344,994. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.527540.0000. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7925.19, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to CompanyIssuer’s capitalization. Premium: USD 12,600,000 22,539,000.00 Premium Payment Date: June 6February 13, 2022 2015 Exchange: New York Stock Exchange The NASDAQ Global Select Market Related Exchange(s): All Exchanges

Trade Date. June 1December 4, 2022 2014 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Nomura Shares: The common stock of Company, par value USD 0.01 0.0001 per share (Exchange symbol “CNMDANIP”) Number of Warrants: 963,3401,798,950. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.527596.21. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7953.45, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 17,955,965.00 Premium Payment Date: June 6December 10, 2022 2014 Exchange: New York Stock Exchange The NASDAQ Global Market Related Exchange(s): All Exchanges

Trade Date. June 1April 28, 2022 2016 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 per share (Exchange symbol “CNMDKN”) Number of Warrants: 963,3402,442,335. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.527521.1050. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7913.40, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 10,192,500 Premium Payment Date: June 6May 4, 2022 2016 Exchange: The New York Stock Exchange Related Exchange(s): All Exchanges

Trade Date. June 1January 27, 2022 2017 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 per share (Exchange symbol “CNMDHZN”) Number of Warrants: 963,340240,240. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.527529.6000. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7919.44, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 1,030,200 Premium Payment Date: June 6February 1, 2022 2017 Exchange: The New York Stock Exchange Related Exchange(s): All Exchanges

Trade Date. June 1January 26, 2022 2017 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 per share (Exchange symbol “CNMDHZN”) Number of Warrants: 963,3401,321,320. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.527529.6000. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7918.76, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 5,666,100 Premium Payment Date: June 6February 1, 2022 2017 Exchange: The New York Stock Exchange Related Exchange(s): All Exchanges

Trade Date. June 1May 17, 2022 2017 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 per share Share (Exchange symbol “CNMDAAWW”) Number of Warrants: 963,340851,308. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.5275. 92.20 Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7959.85, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 6,864,000.00 Premium Payment Date: June 6May 23, 2022 2017 Exchange: New York Stock Exchange The NASDAQ Global Select Market Related Exchange(s): All Exchanges

Trade Date. June 1July 11, 2022 2013 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “"Settlement Terms” " below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 0.001 per share Share (Exchange symbol “CNMD”"HWAY") Number of Warrants: 963,340642,211. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.527525.9520. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7916.22, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s 's capitalization. Premium: USD 12,600,000 1,262,500 Premium Payment Date: June 6July 16, 2022 2013 Exchange: New York Stock Exchange The NASDAQ Global Select Market Related Exchange(s): All Exchanges

Trade Date. June 114, 2022 2013 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 per share Share (Exchange symbol “CNMDMDRX”) Number of Warrants: 963,340654,603. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.527523.1350. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.79, except for any adjustment pursuant to 13.22 (the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization“Strike Price Floor”). Premium: USD 12,600,000 1,670,625.00 Premium Payment Date: June 618, 2022 2013 Exchange: New York Stock Exchange The NASDAQ Global Select Market Related Exchange(s): All Exchanges

Trade Date. June 1, 2022 Effective Date: The second Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 per share (Exchange symbol “CNMD”) Number of Warrants: 963,340. 481,670 For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.5275. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.79, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 6,300,000 Premium Payment Date: June 6, 2022 Exchange: New York Stock Exchange Related Exchange(s): All Exchanges

Trade Date. June 18, 2022 2016 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 0.001 per share (Exchange symbol “CNMDNVRO”) Number of Warrants: 963,340116,741. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.5275127.2775. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7972.73, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 2,160,000 Premium Payment Date: June 613, 2022 2016 Exchange: The New York Stock Exchange Related Exchange(s): All Exchanges

Trade Date. June 1January 24, 2022 2019 Effective Date: The second Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 per share (Exchange symbol “CNMD”) Number of Warrants: 963,340675,648. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.5275114.9225. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7969.6500, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 5,316,000.00 Premium Payment Date: June 6January 29, 2022 2019 Exchange: New York Stock Exchange NASDAQ Global Select Market Related Exchange(s): All Exchanges

Trade Date. June 1May 11, 2022 2016 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 per share (Exchange symbol “CNMDKN”) Number of Warrants: 963,340244,233. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.527521.1050. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7913.06, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 1,019,250 Premium Payment Date: June 6May 13, 2022 2016 Exchange: The New York Stock Exchange Related Exchange(s): All Exchanges

Trade Date. June 1August 23, 2022 2012 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 per share Share (Exchange symbol “CNMDWMGI”) ). Number of Warrants: 963,3403,066,492. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.527529.9250. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7919.95, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s 's capitalization. Premium: USD 12,600,000 8,994,750 Premium Payment Date: June 6August 31, 2022 2012 Exchange: New York Stock Exchange The NASDAQ Global Select Market Related Exchange(s): All Exchanges

Trade Date. June 1February 4, 2022 2020 Effective Date: The second Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 per share (Exchange symbol “CNMDIART”) Number of Warrants: 963,3401,357,390. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.5275113.3400. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7956.67, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 7,750,000 Premium Payment Date: June 6February 7, 2022 2020 Exchange: New York Stock Exchange The NASDAQ Global Select Market Related Exchange(s): All Exchanges

Trade Date. June July 1, 2022 2013 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “"Settlement Terms” " below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 0.001 per share Share (Exchange symbol “CNMD”"HWAY") Number of Warrants: 963,3403,211,056. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.527525.9520. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7916.22, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s 's capitalization. Premium: USD 12,600,000 6,312,500 Premium Payment Date: June 6July 8, 2022 2013 Exchange: New York Stock Exchange The NASDAQ Global Select Market Related Exchange(s): All Exchanges

Trade Date. June 1December 5, 2022 2014 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Nomura Shares: The common stock of Company, par value USD 0.01 0.0001 per share (Exchange symbol “CNMDANIP”) Number of Warrants: 963,340269,843. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.527596.21. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7953.28, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 2,693,399.74 Premium Payment Date: June 6December 10, 2022 2014 Exchange: New York Stock Exchange The NASDAQ Global Market Related Exchange(s): All Exchanges

Trade Date. June 112, 2022 2013 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 per share Share (Exchange symbol “CNMDMDRX”) Number of Warrants: 963,3404,364,018. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.527523.1350. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.79, except for any adjustment pursuant to 13.22 (the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization“Strike Price Floor”). Premium: USD 12,600,000 11,137,500.00 Premium Payment Date: June 618, 2022 2013 Exchange: New York Stock Exchange The NASDAQ Global Select Market Related Exchange(s): All Exchanges

Trade Date. June 114, 2022 2013 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 per share Share (Exchange symbol “CNMDMDRX”) Number of Warrants: 963,340654,603. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.527523.1350. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.79, except for any adjustment pursuant to 13.22 (the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization“Strike Price Floor”). Premium: USD 12,600,000 1,670,625 Premium Payment Date: June 618, 2022 2013 Exchange: New York Stock Exchange The NASDAQ Global Select Market Related Exchange(s): All Exchanges

Trade Date. June 17, 2022 2016 Effective Date: The second third Exchange Business Day immediately prior to the Premium Payment Date Warrants: Equity call warrants, each giving the holder the right to purchase a number of Shares equal to the Warrant Entitlement at a price per Share equal to the Strike Price, subject to the terms set forth under the caption “Settlement Terms” below. For the purposes of the Equity Definitions, each reference to a Warrant herein shall be deemed to be a reference to a Call Option. Warrant Style: European Seller: Company Buyer: Dealer Shares: The common stock of Company, par value USD 0.01 0.001 per share (Exchange symbol “CNMDNVRO”) Number of Warrants: 963,340778,275. For the avoidance of doubt, the Number of Warrants shall be reduced by any Warrants exercised or deemed exercised hereunder. In no event will the Number of Warrants be less than zero. Warrant Entitlement: One Share per Warrant Strike Price: USD 251.5275127.2775. Notwithstanding anything to the contrary in the Agreement, this Confirmation or the Equity Definitions, in no event shall the Strike Price be subject to adjustment to the extent that, after giving effect to such adjustment, the Strike Price would be less than USD 111.7972.73, except for any adjustment pursuant to the terms of this Confirmation and the Equity Definitions in connection with stock splits or similar changes to Company’s capitalization. Premium: USD 12,600,000 14,400,000 Premium Payment Date: June 613, 2022 2016 Exchange: The New York Stock Exchange Related Exchange(s): All Exchanges