Common use of Regulatory Permits Clause in Contracts

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”), except where the failure to possess such permits does not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse Effect, and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all the certificates, authorizations authorizations, and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses its business as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does would not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse Effect, and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Effect (“Material PermitPermits”).

Regulatory Permits. The Company and the its Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local state or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Documents and are operating their respective businesses in compliance with the terms thereof, except where the failure to possess such permits does or operate their business could not, individually or in the aggregate, have or reasonably be expected to have or result in a Material Adverse EffectEffect ("Material Permits"), and neither the Company nor any such Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Significant Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect (“Material Permits”), and neither the Company nor any Significant Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Except as disclosed in the SEC Reports, the Company and the Subsidiaries possess all material certificates, authorizations and permits issued by the appropriate federalfederal (U.S. or Canadian), state, provincial, territorial, local or foreign regulatory authorities (including Environmental Permits) necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”), except where the failure to possess such permits does not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse Effect, and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or or, other than in connection with the Company’s ongoing discussions with regulatory and reimbursement counsel, modification of any Material Permit.

Regulatory Permits. The Company and the Significant Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does could not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect (“Material Permits”), and neither the Company nor any Significant Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the each of its Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their its respective businesses as presently currently conducted and as described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does notpermits, individually or in the aggregate, has not and would not have or reasonably be expected to result in a Material Adverse EffectEffect (“Material Permits”), and neither the Company nor any Subsidiary of its Subsidiaries has received any written notice of proceedings Proceedings relating to the revocation or modification of any such Material PermitPermits.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does notwould not reasonably be expected to, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect ("Material Permits"), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the each of its Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”), except where the failure to possess such permits does not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse Effect, and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The To the best of its knowledge as of the date of this document, the Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently currently conducted and contemplated to be conducted as described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does not, individually or in the aggregate, have or could not reasonably be expected to result in a Material Adverse EffectEffect (“Material Permits”), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the each of its Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local state or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted businesses, including, without limitation, from the U.S. Food and described in Drug Administration (the SEC Reports (“Material PermitsFDA”), except where the failure to possess such permits does not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse Effect, and neither the Company nor any Subsidiary of its Subsidiaries has received any written notice of proceedings relating to the revocation or modification of any such certificate, authorization or permit which, singly or in the aggregate, if the subject of an unfavorable decision, ruling or finding, would have a Material PermitAdverse Effect on the Company and its Subsidiaries, except as described in the SEC Documents.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, if any, and in Pink Sheets, LLC, except where the failure to possess such permits does not, individually or in the aggregate, would not have or reasonably be expected to result in a Material Adverse EffectEffect (“Material Permits”), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, approvals, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Documents, except where the failure to possess such permits does not, and could not have, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect (the "Material Permits"), and neither the Company nor any Subsidiary has not received any written notice of proceedings relating to the revocation or modification of any Material PermitPermits except as described in the SEC Documents.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)) as described in the SEC Reports, except as disclosed in the SEC Reports or where the failure to possess such permits does not, individually or in the aggregate, have or could not reasonably be expected to result in a Material Adverse Effect, and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)and the Memorandum, except where the failure to possess such permits does could not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect (the “Material Permits”), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The To the Company’s knowledge, the Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports Documents (“Material Permits”), except where the failure to possess such permits does not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse Effect, and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, provincial, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”), except where the failure to possess such permits does not, individually or in the aggregate, have or would reasonably be expected to result in a Material Adverse Effect, and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The To the Company’s knowledge, and except as otherwise noted in the SEC Reports, the Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does not, individually or in the aggregate, have or could not reasonably be expected to result in a Material Adverse EffectEffect (“Material Permits”), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The To the knowledge of the Company, the Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does could not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect (“Material Permits”), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”"MATERIAL PERMITS"), except where the failure to possess such permits does not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse Effect, and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”), except where the failure to possess such permits Material Permits does notnot have or could not reasonably be expected to result in, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse Effect, and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)and which are fully operational as of the date of this Agreement, except where the failure to possess such permits does not, individually or in the aggregate, have or could not reasonably be expected to result in a Material Adverse EffectEffect (“Material Permits”), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Registration Statement, the Time of Sale Disclosure Package and the Prospectus, except where the failure to possess such permits does not, individually or in the aggregate, have or would not reasonably be expected to result in a Material Adverse EffectEffect ("Material Permits"), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate Dutch, U.S. federal, state, local or other foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does would not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect (“Material Permits”), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the its Subsidiaries ------------------ possess all certificates, authorizations and permits issued by the appropriate federalFederal, state, local state or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Documents, except where the failure to possess such permits does notwould not reasonably be expected to, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect ("Material Permits"), and neither the Company nor any such Subsidiary has ----------------- received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Registration Statement, the General Disclosure Package, and the Prospectus, except where the failure to possess such permits does not, individually or in the aggregate, have or would not reasonably be expected to result in a Material Adverse EffectEffect (each, a “Material Permit”), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, approvals, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Documents, except where the failure to possess such permits does not, and could not have, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect (the "MATERIAL PERMITS"), and neither the Company nor any Subsidiary has not received any written notice of proceedings relating to the revocation or modification of any Material PermitPermits except as described in the SEC Documents.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)and which are fully operational as of the date of this Agreement, except where the failure to possess such permits does not, individually or in the aggregate, have or would not reasonably be expected to result in a Material Adverse EffectEffect (“Material Permits”), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”), except where the failure to possess such permits does not, individually or in the aggregate, have or would reasonably be expected to result in a Material Adverse Effect, and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate U.S. federal, state, European Union or French provincial, or local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does notpermits, individually or in the aggregate, have or has not and could not reasonably be expected to result in a Material Adverse Effect, and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permitsuch permits.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such certificates, authorizations or permits does could not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse Effect, and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permitsuch certificates, authorizations or permits.

Regulatory Permits. The Company and the each of its Subsidiaries possess possesses all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses its business as presently conducted and described currently conducted, except as set forth in the SEC Reports (“Material Permits”)Reports, except or such that where the failure to possess such permits does notpermits, individually or in the aggregate, has not and would not have or reasonably be expected to result in a Material Adverse EffectEffect (“Material Permits”), and neither the Company nor any Subsidiary of its Subsidiaries has received any written notice of proceedings Proceedings relating to the revocation or modification of any such Material PermitPermits.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations approvals, consents, registrations, licenses, qualifications, certifications, and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does not, individually or in the aggregate, have or would not reasonably be expected to result in a Material Adverse EffectEffect (“Material Permits”), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company Corporation and the each of its Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their its respective businesses business as presently currently conducted and as described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does notpermits, individually or in the aggregate, has not and would not have or reasonably be expected to result in a Material Adverse EffectEffect (“Material Permits”), and neither the Company Corporation nor any Subsidiary of its Subsidiaries has received any written notice of proceedings relating to the revocation or modification of any such Material PermitPermits.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities authorities, including any required permits, licenses and authorizations from the U.S. Food and Drug Administration, necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”), except where the failure to possess such permits does not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse Effect, and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The To the knowledge of the Company, (i) the Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does not, individually or in the aggregate, could not have or reasonably be expected to result in a Material Adverse EffectEffect (“Material Permits”), and (ii) neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports and the Private Placement Memorandum (“Material Permits”), except where the failure to possess such permits does would not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse Effect, and neither the Company nor any Subsidiary has received any written notice of proceedings Proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does notwould not reasonably be expected to, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect ("MATERIAL PERMITS"), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued or issuable by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”), except where the failure to possess such permits does not, individually or in the aggregate, have or and would not reasonably be expected to result in a Material Adverse Effect, and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does would not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect (“Material Permits” ), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess and such certificates, authorizations or permits does not, individually or in the aggregate, have or could not reasonably be expected to result in a Material Adverse EffectEffect (“Material Permits”), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.. 4856-0725-9043, v.7

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does would not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect (each, a “Material Permit”), and except as described in the SEC Reports, neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the each of its Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their its respective businesses business as presently currently conducted and as described in the Company’s SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does permits, individually or in the aggregate, would not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse Effect, and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Effect (“Material PermitPermits”).

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Documents, except where the failure to possess such permits does would not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect (each a “MaterialPermit”), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Documents, except where the failure to possess such permits does would not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect (each a "Material Permit"), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.. 8 (k)

Regulatory Permits. The Company and the Subsidiaries ------------------ possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does would not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect ("Material -------- Permits"), and neither the Company nor any Subsidiary has received ------- any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the each of its Subsidiaries possess possesses all material certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently currently conducted and as described in the SEC Reports (“Material Permits”), except where the failure to possess such permits does not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse Effect, and neither the Company nor any Subsidiary of its Subsidiaries has received any written notice of proceedings Actions relating to the revocation or modification of any such Material PermitPermits.

Regulatory Permits. The To the Company’s knowledge, the Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does could not, individually or in the aggregate, have or reasonably be expected to have or result in a Material Adverse EffectEffect (“Material Permits”), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (collectively, the “Material Permits”), except where the failure to possess such permits does could not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse Effect, and neither . Neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The To the Company's knowledge, the Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does would not, individually or in the aggregate, have or reasonably be expected to have or result in a Material Adverse EffectEffect ("MATERIAL PERMITS"), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective current businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such certificates, authorizations and permits does could not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect (“Material Permits”), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such certificates, authorizations or permits does could not, individually or in the aggregate, have or reasonably be expected to have or result in a Material Adverse EffectEffect (such certificates, authorizations and permits, the "Material Permits"), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Significant Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does could not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect ("Material Permits"), and neither the Company nor any Significant Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”), except where the failure to possess such permits does would not, individually or in the aggregate, have or reasonably be expected to result in have a Material Adverse Effect, and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Except as disclosed in Schedule 2.1(w), the Company and the Subsidiaries possess all franchises, certificates, licenses, authorizations and permits or similar authority issued by the appropriate federal, state, local state or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”), Documents except where the failure to possess such permits does would not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect ("Material Permits"), and neither the Company nor any such Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities or self-regulatory organizations necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”), except where the failure to possess have such permits does could not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse Effect, and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permitsuch permits.

Regulatory Permits. The Company and the each of its Subsidiaries possess possesses all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses its business as presently conducted and described currently conducted, except as set forth in the SEC Reports (“Material Permits”)Reports, except or where the failure to possess such permits does notpermits, individually or in the aggregate, have or has not and would not reasonably be expected to result in a Material Adverse EffectEffect (“Material Permits”), and neither the Company nor any Subsidiary of its Subsidiaries has received any written notice of proceedings Proceedings relating to the revocation or modification of any such Material PermitPermits.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, provincial, territorial, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Documents, except where the failure to possess such permits does not, individually or in the aggregate, have or could not reasonably be expected to result in a Material Adverse EffectEffect (“Material Permits”), including, but not limited to, all Material Permits to purchase gold, and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all ------------------ certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does would not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect ("Material -------- Permits"), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the its Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local state or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse Effect, and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.except

Regulatory Permits. The Company and the its Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local state or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Documents and are operating their respective businesses in compliance with the terms thereof, except where the failure to possess such permits does or operate their business could not, individually or in the aggregate, have or reasonably be expected to have or result in a Material Adverse Effect, and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.Adverse

Regulatory Permits. The Company and the Subsidiaries possess all certificates, approvals, authorizations and permits issued by the appropriate federal, state, local or foreign from all regulatory authorities and agencies necessary to own, lease or operate their respective properties and assets and conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)conducted, except where the failure to possess such permits does not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse Effect, and neither the Company nor any Subsidiary has received any written notice of proceedings Proceedings relating to the revocation or modification of any Material Permitsuch certificate, approval, authorization or permit.

Regulatory Permits. The Company and the Subsidiaries its subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, provincial, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports Time of Sale Information (“Material Permits”), except where the failure to possess such permits does not, individually or in the aggregate, have have, or would not reasonably be expected to result in in, a Material Adverse Effect, and neither the Company nor any Subsidiary subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The To the Company’s knowledge, the Company and the Material Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”), except where the failure to possess such permits does not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse Effect, and neither the Company nor any Material Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does could not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect (the “Material Permits”), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does would not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect ("MATERIAL PERMITS"), and neither the Company nor any Subsidiary has received any written notice of proceedings any Action relating to the revocation or modification of any Material Permit.

Regulatory Permits. The To the knowledge of the Company, the Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does could not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect ("Material Permits"), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Material Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect (“Material Permits”), and neither the Company nor any Material Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective current businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such certificates, authorizations and permits does could not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect ("Material Permits"), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The To the Company’s knowledge, the Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports Documents (“Material Permits” and, such business, the “Business”), except where the failure to possess such permits does not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse Effectmaterially affect the Business, and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does would not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect ("Material Permits"), and neither the Company nor any Subsidiary has received any written notice of proceedings any Action relating to the revocation or modification of any Material Permit.

Regulatory Permits. The To the Company’s knowledge, the Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”), except where the failure to possess such permits does not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse Effect, and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such any such certificates, authorizations or permits does could not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse Effect, and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permitsuch certificates, authorizations or permits.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”), except where the failure to possess such permits does is not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse Effect, and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries ------------------ possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does could not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect ("Material Permits"), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the its Subsidiaries possess all certificates, authorizations authorizations, approvals, licenses and permits issued by the appropriate federal, state, local state or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in at the SEC Reports time this representation is made (“Material Permits”), except where the failure to possess such permits does notPermits would not have, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse Effect, and neither the Company nor any Subsidiary of its Subsidiaries has received any written notice of proceedings relating to the revocation or modification of any Material such Permit.

Regulatory Permits. The Company and the each of its Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently currently conducted and as described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does notpermits, individually or in the aggregate, has not and would not have or reasonably be expected to result in a Material Adverse EffectEffect (“Material Permits”), and neither the Company nor any Subsidiary of its Subsidiaries has received any written notice of proceedings Proceedings relating to the revocation or modification of any such Material PermitPermits.

Regulatory Permits. The Company and the Subsidiaries possess all ------------------- certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does would not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect ("MATERIAL PERMITS"), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. To Company’s Knowledge: The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does could not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect (“Material Permits”), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries ------------------ possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does would not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect ("Material -------- Permits"), and neither the Company nor any Subsidiary has received any written notice of ------- proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)its most recently filed Annual Report on Form 10-K, except where the failure to possess such permits does could not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect (“Material Permits”), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does not, individually or in the aggregate, could not have or reasonably be expected to result in a Material Adverse EffectEffect (“Material Permits”), and Oculus Innovative Sciences, Inc. Page 8 neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Offering Statement, the General Disclosure Package and the Offering Circular, except where the failure to possess such permits does not, individually or in the aggregate, have or would not reasonably be expected to result in a Material Adverse EffectEffect ("Material Permits"), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and each of the Subsidiaries possess all certificates, authorizations authorizations, licenses, registrations and permits issued by the appropriate federal, state, local or foreign regulatory authorities any Governmental Authority which are necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does would not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect ("MATERIAL PERMITS"), and neither the Company nor any Subsidiary of the Subsidiaries has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the each of its Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their its respective businesses business as presently currently conducted and as described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does notpermits, individually or in the aggregate, has not and would not have or reasonably be expected to result in a Material Adverse EffectEffect (“Material Permits”), and neither the Company nor any Subsidiary of its Subsidiaries has received any written notice of proceedings relating to the revocation or modification of any such Material PermitPermits.

Regulatory Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)filed prior to the date hereof, except where the failure to possess such permits does not, individually or in the aggregate, have or could not reasonably be expected to result in be material to the Company and its Subsidiaries, taken as a whole (“Material Adverse EffectPermits”), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.

Regulatory Permits. The Company and the Subsidiaries possess all ------------------ certificates, authorizations and permits issued by the appropriate federal, state, local or foreign regulatory authorities necessary to conduct their respective businesses as presently conducted and described in the SEC Reports (“Material Permits”)Reports, except where the failure to possess such permits does would not, individually or in the aggregate, have or reasonably be expected to result in a Material Adverse EffectEffect ("Material Permits"), and neither the Company nor any Subsidiary has received any written notice of proceedings relating to the revocation or modification of any Material Permit.