Common use of Prohibited Uses Clause in Contracts

Prohibited Uses. a) The Licensee shall use reasonable efforts to ensure that the Authorised Users are aware of the prohibitions on the use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. (a) The Licensee shall use reasonable efforts to ensure that the Authorised Users are aware of the prohibitions on Tenant will not use, occupy or permit the use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users or occupancy of any of the provisions Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of this Licenceany (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the provisions set out belowoffice of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Authorised Users may not: i) Remove Tenant shall not keep or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or permit to be kept any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyonesubstance in, or transmit conduct or permit to be conducted any part of the Licensed Material (other than Metadata) by any means to anyoneoperation from, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) This clause 5Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall continue not commit or permit to apply after termination be committed any action or circumstance in or about any of this Licence for the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any reasoninsurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.

Prohibited Uses. Tenant shall not use, permit the use of, permit anything to be done in or on or anything to be brought into or onto or kept in or on the Premises, the Building, the Property or any part of thereof (i) which would violate any covenant, agreement, term, provision or condition of this Lease, (ii) for any unlawful purpose or in any unlawful manner, or (iii) which, in the reasonable judgment of Landlord shall in any way (a) The Licensee shall use reasonable efforts impair or tend to ensure that impair the Authorised Users are aware appearance or reputation of the prohibitions on Building or the Property, (b) impair or interfere with or tend to impair or interfere with any of the Building or Property services or the proper and economic heating, cleaning, air conditioning or other servicing of the Building or the Property or any portion thereof or with the use of the Licensed Materials set out in this Licence and Building or the Licensee shall use reasonable endeavours Property or any portion thereof, or (c) occasion discomfort, inconvenience or annoyance to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use any other tenant, licensee or other occupant of the Licensed MaterialsBuilding or the Property or any neighboring property, whether through the transmission of noise or odors or vibrations or otherwise. The Licensee shall be liable for any breach by Authorised Users of any Without limiting the generality of the provisions of this Licenceforegoing, including but Tenant shall not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or permit any and all disclaimers as they appear vending machines in the Licensed Materials; ii) Systematically make print Premises or electronic copies use or occupy or permit the use or occupation of multiple extracts the Premises or make multiple copies of any part of the Licensed Materials Premises as or for a restaurant business or for the sale or furnishing free of charge of food, liquors, frozen desserts, ice cream, beverages, or other edible products, for public stenography, or for the conducting of any purpose aspect of banking business; no food shall be prepared or served for consumption on or about the Premises; no intoxicating liquors or alcoholic beverages shall be sold or otherwise permitted in or about the Premises, the Building or elsewhere on the Property; no lottery tickets (even where the sale of such tickets is not illegal) shall be sold and no gambling, betting or wagering shall otherwise be permitted in or about the Premises, the Building or elsewhere on the Property; no loitering shall be permitted in or about the Premises, the Building or elsewhere on the Property; and no loading or unloading of supplies or other than that material to or from the Premises shall be permitted in the Building or elsewhere on the Property except at times and in locations to be designated by this Licence; iii) Prepare derivative works Landlord. Tenant shall not bring or downloadpermit to be brought into or keep in or on the Premises, mount the Building or distribute elsewhere on the Property any part of the Licensed Material on oil or any electronic system toxic, hazardous, inflammable, combustible or networkexplosive fluids, materials, chemicals or substances, (including without limitation any hazardous substances within the Internet meaning of Chapter 2 IE of the Massachusetts General Laws and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials any medical waste or any part of them for any purpose whatsoever fluid, material, chemical or incorporate any part of any Licensed Materials substance considered to be biologically hazardous) (whether except in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access Premises where’ such are related to and/or permit Tenant’s use of the Licensed Content by anyonePremises, provided that the same are stored and handled in a proper fashion consistent with applicable legal standards), or transmit cause or permit any part odors to emanate from or permeate the Premises. The Premises shall be maintained in a sanitary condition, and kept free of rodents and vermin. Tenant shall suitably store all trash and rubbish in the Premises, the Building or elsewhere on the Property in locations designated by Landlord from time to time. The language of this Section prohibiting the preparation or serving of food for consumption on or about the Premises notwithstanding, but subject to the other terms and conditions of the Licensed Material Lease and subject to the other terms and conditions of this Section entitled “Prohibited Uses.”, (other than Metadataincluding, without limitation, the prohibition against intoxicating liquors and alcoholic beverages), (i) Tenant’s employees and invitees may prepare, serve and consume food and beverages (a) which are brought into the Premises by any means to anyonesuch persons for their own consumption, other than an Authorised User(b) are in the nature of snacks, except as otherwise may be permitted under Appendix B coffee or soda and provided by the Tenant or (including by way of inter-library lending). c) The Licensee must seek are typically prepared, served and obtain The Company consumed in typical first class office space in Newton and Boston, Massachusetts, provided however that such preparation, serving and consumption shall be done in a manner typical to first class office space in Newton and Boston, Massachusetts, and (ii), Tenant may, with Landlord’s prior written consent, install at Tenant’s sole expense, one bottled water dispenser (utilizing water bottles with a capacity of Biologists’ permission prior not more than five gallons each and dispensing not more than one bottle at a time without manually removing and replacing the one bottle from which water is dispensed), coffee maker, microwave and refrigerator for use by Tenant. Landlord consents to carrying out or attempting to carry out any the installation by Tenant at Tenant’s sole expense, of one bottled water dispenser (as described in the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇immediately preceding sentence), a coffee maker, a microwave and a refrigerator for use by Tenant.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. (a) The Licensee Throughout the Term, Landlord shall use reasonable efforts to ensure that not further develop the Authorised Users are aware Property, other than consistent with the provisions of this Lease, and, without limiting the prohibitions on the use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee generality thereof, no such further development shall be liable for any breach by Authorised Users of any permitted if (1) the same would cause a violation of the provisions of this LicenceSection 4.8(b) hereof or Section 14.20 hereof, including but not limited or (2) the same would otherwise result in (i) an increase in the amount of any Additional Rent payable by Tenant hereunder, (ii) any other cost or expense being imposed upon Tenant or any Tenant Party, (iii) any reduction in the value of the Leased Premises to Tenant or any Tenant Party, (iv) parking or traffic flow on the provisions set out belowProperty being adversely affected from the perspective of Tenant or any Tenant Party, (v) any reduction in the function or utility of the Common Areas (or any portion thereof) from the perspective of Tenant or any Tenant Party. (b) Authorised Users may not: i) Remove Throughout the Term, Landlord shall not use, or alter permit the author’s name(s) or use of, the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials Property (or any part of them thereof) for any purpose whatsoever Prohibited Uses. The term “Prohibited Uses” shall mean (i) any use that emits an obnoxious odor, noise or incorporate sound that can be heard or smelled outside of the premises; (ii) any part use in violation of any Licensed Materials (whether in amended zoning regulations or unamended form) into any other work governmental restrictions applicable to the Property; (iii) any use that, by its nature, (even if such use is legally permissible) would result in parking or traffic flow on the Property being materially adversely affected from the perspective of Tenant or any Tenant Party; (iv) any operation primarily used as a warehouse or storage facility, assembling or manufacturing, distilling, refining, rendering, processing, smelting, agricultural or mining operations; (v) any mobile home park or sales, trailer court, labor camp, junk yard or stockyard; (vi) make any Commercial Use central laundry, dry cleaning plant or laundromat; provided, however, this prohibition shall not be applicable to on-site services oriented only to pickup and delivery by consumers; (vii) any automobile, truck, trailer or recreational vehicle sales, leasing, display, repair or body shop; (viii) any living quarters, sleeping apartments, hotel or lodging rooms; (xi) veterinary hospitals, animal raising or breeding facilities, animal boarding facilities or pet shops; (x) mortuaries or funeral homes; (xi) any establishment that sells, rents or exhibits pornographic materials; (xii) massage parlors or any form of sexually oriented business (including novelty merchandise sales); (xiii) bars, taverns or brew pubs; (xiv) flea markets, amusement or video arcades, computer game rooms, pool or billiard halls, bingo halls, dance halls, discos or night clubs; (xv) sales of paraphernalia for use with illicit drugs; (xvi) carnivals, amusement parks or circuses; (xvii) pawn shops, auction houses, second hand stores, consignment shops, army/navy surplus stores or gun shops; (xviii) gambling facilities or sports betting parlor; (xix) churches, synagogues or other places of worship; (xx) assembly halls or meeting facilities; (xxi) technical or vocational schools or any other operation primarily engaged in education or training activities; (xxii) medical clinics, abortion clinics, medical laboratories or screening facilities; (xxiii) any agency (public or private) providing health, welfare, social or human services, or (xxiv) tattoo parlors, fortune telling or spiritual readings; (xxv) facilities that collect donated goods and products; (xxvi) bowling alleys, skating rinks, archery or gun ranges, (xxvii) postal facilities, tax collectors, tag agencies, jails or detention centers, courthouses or any other form of agency dealing with civil authority. Notwithstanding the foregoing, the term “Prohibited Uses” shall not include any use which is permitted under a third party tenant lease of space in the Building which is in effect as of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing usesCommencement Date. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.________________________________________________________________________________________________________________________

Prohibited Uses. aTenant shall not use the Premises: (i) The Licensee shall use reasonable efforts to ensure that the Authorised Users are aware In violation of the prohibitions on the use restrictive covenants described in Section 9.10 of the Licensed Materials set out that certain Declaration of Protective Covenants and Owners Association for Cool Springs East Side dated October 4, 1994, of record in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable Book 1235, page 725, Register’s Office for any breach by Authorised Users of any of the provisions of this Licence, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇▇ County, Tennessee (the “Protective Covenants”), a copy of which has been provided by Landlord to Tenant, or in violation of the rules and regulations described in Section 12b hereof; (ii) In any manner that constitutes a nuisance or trespass, or will in any way violate any law, statute, ordinance or governmental rule or regulation now in force or which may hereafter be enacted or promulgated, (iii) In any manner that will adversely affect or interfere with any services required to be furnished by Landlord to Tenant, or to any other tenants or occupants of the Building or with the proper and economical rendition of any such service. d(iv) This clause 5) shall continue In any manner that will in any way obstruct or interfere with the rights of other tenants of the Building or injure them, or use or allow the Premises to apply after termination of this Licence be used for any reasonunlawful purpose, or commit or suffer to be committed any waste in, on or about the Premises; (v) In any manner which increases any insurance premiums, or makes such insurance unavailable to Landlord on the Building; provided that, in the event of an increase in Landlord’s insurance premiums which results from Tenant’s use of the Premises, Landlord may elect to permit the use and charge Tenant for the increase in premiums, and Tenant’s failure to pay Landlord, on demand, the amount of such increase shall be an event of default (in any action or proceeding wherein Landlord and Tenant are parties, a schedule or “make up” of rates applicable to the Building issued by the Tennessee Insurance Bureau, or other similar body fixing such fire insurance rates, shall be conclusive evidence of the facts therein stated and the several items and charges in the fire insurance rates therein); (vi) In any manner that creates unusual demands for electricity, heating or air conditioning (except as permitted by Section 4(c) below); or (vii) For any purpose except the Permitted Use, unless consented to by Landlord in writing. (viii) That shall cause or permit the use, generation, storage or disposal in or about the Premises or the Building of any substances, materials or wastes subject to regulation under Federal, State or local laws from time to time in effect concerning hazardous, toxic or radioactive materials (excluding the storage and use of normal cleaning supplies and office supplies customarily used for the Permitted Use, all of which shall be permitted without Landlord’s consent so long as such items are stored and used in compliance with applicable environmental laws), unless Tenant shall have received Landlord’s prior written consent, which Landlord may withhold or at any time revoke in its sole discretion.

Prohibited Uses. a) The Licensee Tenant shall not use reasonable efforts the Premises or permit anything to ensure be done in or about the Premises nor keep or bring anything in the Premises that the Authorised Users are aware will in any way conflict with any of the prohibitions requirements of the Board of Fire Underwriters or similar body now or hereafter constituted or in any way increase the existing rate of or affect any policy of fire or other insurance upon the Buildings or any of their contents, or cause a cancellation of any insurance policy (unless Tenant pays such rate increase). No auctions may be held or otherwise conducted in, on or about the Premises or anywhere else in the Property without Landlord’s prior written consent, which Landlord may withhold in its sole discretion. Tenant shall not do, and shall not permit any other Tenant Party to do, anything in the Property that will in any way obstruct or interfere with the rights of Landlord, other tenants or occupants of the Property, or other persons or businesses in the area, or injure or unreasonably annoy other tenants or use or allow the Premises to be used for any unlawful purpose, as determined by Landlord, in its reasonable discretion, for the benefit, quiet enjoyment and use by Landlord and all other tenants or occupants of the Buildings; nor shall Tenant cause, maintain or permit any private or public nuisance in, on or about the Premises or any other part of the Property, including, but not limited to, any offensive odors, noises, fumes or vibrations. Tenant shall not damage or deface or otherwise commit or suffer to be committed any waste in, upon or about the Premises. Tenant shall not place or store, nor permit any other person or entity to place or store, any property, equipment, materials, supplies, personal property or any other items or goods outside of the Premises other than in compliance with all applicable Laws. Tenant shall place no loads upon the floors, walls, or ceilings in excess of the maximum designed load permitted by the applicable Uniform Building Code or that may damage the Premises or outside areas; nor place any harmful liquids in the drainage systems; nor dump or store waste materials, refuse or other such materials, or allow such to remain outside the Premises, except in refuse dumpsters, storage tanks or in any enclosed trash areas provided. Tenant shall comply with all applicable Laws, Recorded Matters, and the Rules and Regulations applicable to its use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use Premises, any other areas of the Licensed MaterialsProperty Landlord reserves for Tenant’s exclusive use, and/or the Common Area. The Licensee shall be liable for any breach by Authorised Users of any of If Tenant fails to so comply with such Laws, Recorded Matters, Rules and Regulations, or the provisions of this LicenceLease, including Landlord shall have rights and remedies of Landlord under this Lease including, but not limited to, the payment by Tenant to the provisions set out below. b) Authorised Users may not: i) Remove or alter the authorLandlord of all Enforcement Expenses and Landlord’s name(s) or the publisher’s copyright notices or other means of identification or any costs and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or downloadexpenses, mount or distribute any part of the Licensed Material on any electronic system or networkif any, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out cure any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇such failures of Tenant, if Landlord, at its sole option, elects to undertake such cure.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. Tenant shall not use, or suffer or permit the use of, or suffer or permit anything to be done in or anything to be brought into or kept in, the Demised Premises or any part thereof (i) which would violate any of the covenants, agreements, terms, provisions and conditions of this Lease, (ii) for any unlawful purposes or in any unlawful manner, or (iii) which, in the reasonable judgment of Landlord shall in any way (a) The Licensee shall use reasonable efforts impair or tend to ensure that impair the Authorised Users are aware appearance or reputation of the prohibitions on Building, (b) impair or interfere with or tend to impair or interfere with any of the Building services or the proper and economic heating, cleaning, air conditioning or other servicing of the Building or with the use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part areas of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyoneBuilding, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior occasion discomfort, inconvenience or annoyance to carrying out or attempting to carry out any of the foregoing usesother tenants or occupants of the Building, whether through the transmission of noise or odors or otherwise. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5Without limiting the generality of the foregoing, no food shall be prepared or served for consumption by the general public on or about the Demised Premises; no intoxicating liquors or alcoholic beverages shall be sold or otherwise served for consumption by the general public on or about the Demised Premises; no lottery tickets (even where the sale of such tickets is not illegal) shall continue be sold and no gambling, betting or wagering shall otherwise be permitted on or about the Demised Premises; no machinery shall be operated in the Demised Premises if such operation involves vibratory motion of any kind perceptible outside the Demised Premises; no loitering shall be permitted on or about the Demised Premises; and no loading or unloading of supplies or other material to apply after termination or from the Demised Premises shall be permitted on the Land except at times and in locations to be designated by Landlord. The Demised Premises shall be maintained in a sanitary condition, and kept free of this Licence for any reasonrodents and vermin. All trash and rubbish shall be suitably stored in the Demised Premises or other locations designated by Landlord from time to time.

Prohibited Uses. Owner shall not use, or permit the use of, the Complex Site for any other, different or additional purpose that is not a Permitted Use without first obtaining the Approval of the City Representative. Owner agrees that the Permitted Uses are subject to Owner’s compliance with all Applicable Law at any time applicable to the use, occupancy or operation of the Complex Site. Notwithstanding the Permitted Uses hereunder, Owner agrees that it shall not (collectively, the “Prohibited Uses”): (a) The Licensee Create, cause, maintain or permit any public or private nuisance in, on or about the Complex Site; provided, however, in no event shall use reasonable efforts a City Party be entitled to ensure assert that a Permitted Use held in compliance with Applicable Law constitutes a public or private nuisance; (b) Use or allow the Authorised Users are aware Complex Site to be used for the sale or display of any pornographic material or material which is obscene under standards set forth in any Applicable Law, or operate or allow any Person to operate in, on or about the Complex Site any “Adult Business” as defined in Sec. 138-418 of the prohibitions City Codes; (c) Use or allow the Complex Site to be used in violation of the special warranty deed from the MEDC to Owner or Applicable Law; (d) Except in connection with conventions, trade shows and other similar events and subject to rules, regulations and policies promulgated by the City, use or allow the Complex Site to be used for the public display or public or private sale of guns and other weapons, ammunition or explosives, including fireworks; (e) Use or allow the Complex Site to be used for the sale or commercial display of any lewd, offensive or immoral sign or advertisement, including any sign or advertisement that promotes lewd, offensive or immoral activities, including sexually immoral activities; (f) Use or allow the Complex Site to be used for the sale of paraphernalia or other equipment or apparatus which is used primarily in connection with the taking or use of illegal drugs; (g) Use or allow the Project Improvements or the Complex Site to be used as a place of permanent residence by any Person; (h) Use or permit the Complex Site to be used for a shooting gallery, target range, vehicle repair facility, car wash facility, warehouse (but any area for the storage of goods intended to be sold or used in connection with Owners’ operations permitted hereunder shall not be deemed to be a warehouse), convalescent care facility or mortuary, or use or permit the Complex Site to be used for any assembly, manufacture, distillation, refining, smelting or other industrial or commercial operation or use (excluding, for the avoidance of doubt, a restaurant or other eatery in the concept of a restaurant-brewery, or “brewpub”); except to the extent permitted by the Project Specifications or otherwise permitted in this Agreement with respect to naming rights, installing any advertisements, signs, decorations or displays of any kind on the exterior of the Complex; or (i) Use or permit the use of the Licensed Materials set out in this Licence and Complex Site for illegal gambling; or (j) Use or permit the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed MaterialsComplex Site as a massage parlor or a tanning parlor. The Licensee shall be liable for any breach by Authorised Users of any of the provisions of this LicenceSection 12.2 shall inure to the benefit of and be enforceable by City Parties and their successors and assigns. No other Person, including but not limited any guest or patron of the Complex Site, shall have any right to enforce the prohibitions as to the provisions set out belowProhibited Uses. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee Tenant further covenants and agrees that Tenant shall not use, or knowingly suffer or permit any person or persons to use, the Premises or any part thereof for any use reasonable efforts or purpose in violation of Applicable Laws including, without limitation, any such Applicable Laws relating to ensure that Hazardous Materials, or any Underlying Documents. Landlord shall have the Authorised Users are aware of the prohibitions on right to impose reasonable, nondiscriminatory and customary rule and regulations regarding the use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure Project that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and unreasonably interfere with Tenant’s use of the Licensed MaterialsPremises, as reasonably deemed necessary by Landlord with respect to the orderly operation of the Project (“Rules and Regulations”), and Tenant shall comply with such reasonable rules and regulations; provided that (i) Landlord shall not enforce, change or modify such rules and regulations in a discriminatory manner, (ii) such rules and regulations shall do not unreasonably interfere with the normal and customary conduct of Tenant’s business, (iii) any such rules and regulations shall not materially increase Tenant’s obligations hereunder, materially decrease Tenant’s rights hereunder, or materially decrease Landlord’s obligations hereunder, and (iv) Landlord shall provide Tenant with at least thirty (30) days’ prior written notice of any such rules and regulations. The Licensee Tenant shall not do or permit anything to be liable done in or about the Premises which will in any way obstruct or interfere with the rights of other tenants or occupants of the Building, or injure or annoy them or use or allow the Premises to be used for any breach by Authorised Users of improper, unlawful or objectionable purpose, nor shall Tenant cause, maintain or permit any of nuisance in, on or about the provisions of this LicencePremises. Tenant shall comply with, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@’s rights and obligations under the Lease and ▇▇▇▇▇▇’s use of the Premises shall be subject and subordinate to, all recorded easements, covenants, conditions, and restrictions now or hereafter affecting the Project, so long as the same do not unreasonably interfere with ▇▇▇▇.▇▇▇’s use of the Premises or parking rights or materially increase Tenant’s obligations or decrease Tenant’s rights under this Lease. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee Premises shall not be used for any use reasonable efforts which conflicts with any existing declaration of restrictions or covenants or other agreement recorded against or binding upon the Premises or any existing mortgage or deed of trust In addition, the Premises, shall not be used for any use other than the use permitted by Section 9 including,- without limitation, any use- which conflicts with or otherwise violates any exclusive uses granted by Landlord to ensure that other tenants, as set forth on Exhibit "D". Tenant shall not do or permit anything to be done in or about the Authorised Users are aware Premises which will obstruct or interfere with the rights of other tenants or occupants of the prohibitions Shopping Center, or injure or annoy them or use or allow the Premises to be used for any improper, immoral, unlawful or objectionable purpose, nor shall Tenant cause, maintain or permit any nuisance in, on or about the Premises. Tenant shall not install, maintain or use an underground storage tank. Tenant shall not do or permit anything to be done which will invalidate or increase the cost of any fire, extended coverage or any other insurance policy covering the Licensed Materials set out Premises, the Shopping Center and/or property located therein. Tenant shall promptly pay or reimburse Landlord, as additional rent, the full amount of any additional premium charged Landlord for any insurance policy by reason of Tenant's failure to comply with this Section and/or the Section entitled "Compliance with Law"; provided, mat except in the case of a use by Tenant that is expressly permitted by the terms of this Lease, such reimbursement shall not be Landlord's exclusive remedy, nor shall it limit or compromise any other rights granted Landlord by this Lease or by law or equity. Nothing contained in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee Section 10 shall be liable for construed or deemed in any breach by Authorised Users way to increase the scope of any of the provisions Tenant's use set forth in Section 9 of this Licence, including but not limited to the provisions set out belowLease. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee In no event shall Tenant use reasonable efforts to ensure that the Authorised Users are aware of the prohibitions on the use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials Premises for any retail sales activity or for any of the following noxious uses: (i) a second hand or surplus store; (ii) a mobile home park or trailer court; (iii) a fire, bankruptcy or auction sale; (iv) a laundry or dry cleaning operation; (v) automobile, truck, R.V. sales, leasing, display or repair; (vi) mortuary; (vii) any center for medical procedures, counseling or activities related to abortion, birth control or euthanasia; (viii) any establishment selling or exhibiting pornographic materials; (ix) an auto parts store or gas station; (x) any church, synagogue, mosque, temple or other place of worship; (xi) a “head” shop or any establishment displaying or selling drug paraphernalia; (xii) a massage parlor, topless bar or club or restaurant which provides striptease entertainment; (xiii) a landfill, garbage dump or for the dumping, disposal, incineration or storage of garbage or any business storing or handling hazardous materials except in the course of a Permitted Use; (xiv) any carnival or amusement park; (xv) a temporary placement service; (xvi) a drug or alcohol recovery or treatment facility; (xvii) a school or trade school; or (xviii) an off track betting facility or betting club or any other type of gambling establishment. Tenant shall not do or permit anything to be done in or about the Premises that will in any way cause a nuisance, obstruct or interfere with the rights of neighbors or injure or annoy them. Tenant shall not use the Premises, nor allow the Premises to be used, for any purpose other than or in any manner that permitted by this Licence; iii) Prepare derivative works would invalidate any policy of insurance now or downloadhereafter carried on the Building or the Premises. Landlord may promulgate and modify from time to time rules and regulations for the safety, mount care or distribute any part cleanliness of the Licensed Material on any electronic system or networkPremises which shall be complied with by Tenant and its employees, including without limitation the Internet agents, visitors and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)invitees. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee Tenant shall not use reasonable efforts the Premises or allow the Premises to ensure be used for any illegal or immoral purpose, or so as to create waste, or constitute a private or public nuisance. Tenant shall not place any loads upon the floors, wails, or ceiling that endanger the Authorised Users are aware of the prohibitions on the structure, or overload existing electrical or other mechanical systems. Tenant shall not use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materialsany machinery or equipment which causes any substantial noise or vibration. The Licensee No waste materials or refuse shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited dumped upon or permitted to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of remain upon any part of the Licensed Materials Premises or outside of the Premises except in trash containers placed inside exterior enclosures designated by Landlord for that purpose or inside of the Premises where approved by Landlord, No materials, supplies, equipment, finished products or semi-finished products, raw materials or articles of any nature shall be stored upon or permitted to remain outside the Premises or on any portion of the Common Area unless otherwise approved by Landlord in its sole discretion. No loudspeaker or other device, system or apparatus which can be heard outside the Premises shall be used in or at the Premises without the prior written consent of Landlord. No explosives or firearms shall be brought into the Premises. Landlord shall have the right to enter and conduct an inspection of the Premises, at any reasonable time and upon reasonable advance notice (of not less than 24 hours, except in the case of an emergency in which event no prior notice shall be required, but Landlord shall give Tenant prompt notice following such emergency entry), to determine whether Tenant is complying with the terms of this Section 6.2. In the event such inspection identifies any deficiencies in Tenant’s compliance with the terms of this Section 6.2, Tenant shall promptly correct such deficiency and shall reimburse Landlord within thirty (30) days after written demand as Additional Rent for any purpose other than that permitted costs incurred by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved Landlord in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)connection with such inspection. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee Tenant and Tenant's agents shall use reasonable efforts not commit or suffer to ensure that be committed any waste upon the Authorised Users are aware Premises. Tenant and Tenant's agents shall not do or permit anything to be done in or about the Premises or Common Area which will in any way obstruct or interfere with the rights of any authorized users of the prohibitions Common Area, or injure or annoy them. Tenant shall not conduct or permit any auction or sale open to the public to be held or conducted on or about the Premises or Common Area. Tenant and Tenant's agents shall not use or allow the Premises to be used for any unlawful or hazardous purpose or any purpose not permitted by this Lease, nor shall Tenant or Tenant's agents cause, maintain, or permit any nuisance in, on or about the Premises. Tenant and Tenant's agents shall not do or permit anything to be done in or about the Premises or Common Area nor bring or keep anything in the Premises or Common Area which will in any way increase the rate of any insurance upon the Premises or Common Area or any part thereof or any of its contents, or cause a cancellation of any insurance policy covering the Premises or Common Area or any part thereof or any of its contents, nor shall Tenant or Tenant's agents keep, use or sell or permit to be kept, used or sold in or about the Premises any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance upon the Premises or Common Area or any part thereof or any of its contents is increased because of the acts or omissions of Tenant or Tenant's agents, Tenant shall pay, as Additional Rent, the full cost of such increase to the extent attributable solely to Tenant's or its agents' acts or omissions; provided however this provision shall in no event be deemed to constitute a waiver of Landlord's rights or remedies in connection with such increase. Tenant and Tenant's agents shall not place any loads upon the floor, walls or ceiling of the Premises which would endanger the Premises or the structural elements thereof, nor place any harmful liquids in the drainage system of the Premises. No waste materials or refuse shall be dumped upon or permitted to remain upon any part of the Premises or Common Area except in enclosed trash containers. No materials, supplies, equipment, finished products (or semi-finished products), raw materials, or other articles of any nature shall be stored upon, or be permitted to remain on, any portion of the Common Area. Tenant shall not allow any activity which in the reasonable opinion of Landlord is detrimental to the operation of the Common Area or to tenants of Landlord in other buildings located on the use of Common Area or upon real property owned by Landlord adjacent to the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users of any of the provisions of this LicenceCommon Area, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices any picketing, work stoppage, or other means concerted activity. Landlord shall have the right to require Tenant, at Tenant's own expense and within a reasonable period of identification time, to use Tenant's commercially reasonable efforts to terminate or control any and all disclaimers as they appear in such picketing, work stoppage or other concerted activity to the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of extent necessary to eliminate any part interference with the operation of the Licensed Materials for any purpose other than that permitted Common Area or such tenants. Failure by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User Tenant to use its commercially reasonable efforts to do so; v) Alter, edit, abridge so shall be a Default by Tenant. Nothing contained in this paragraph shall be construed as placing Landlord in an employer-employee relationship with any of Tenant's employees or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into with any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise employees who may be permitted under Appendix B (including by way of inter-library lending)involved in such activity. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee uses prohibited under this Lease shall use reasonable efforts to ensure that the Authorised Users are aware of the prohibitions on the include, without limitation, use of the Licensed Materials set out in this Licence and Premises or a portion thereof for (i) offices of any agency or bureau of the Licensee United States or any state or political subdivision thereof; (ii) offices or agencies of any foreign governmental or political subdivision thereof; (iii) offices of any health care professionals or service organization; (iv) schools or other training facilities which are not ancillary to corporate, executive or professional office use; (v) retail or restaurant uses; or (vi) communications firms such as radio and/or television stations. Tenant shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect allow occupancy density of their access to and use of the Licensed MaterialsPremises which is greater than eight (8) persons per 1,000 rentable square feet of space located in the Premises. The Licensee Notwithstanding the foregoing, subject to the following terms, Tenant shall be liable permitted to allow occupancy density of use of the Premises which is greater than such foregoing ratio, provided that (i) Tenant shall provide Landlord with reasonable advance notice of such anticipated increased occupancy density, (ii) in no event shall Tenant allow occupancy density of use of the Premises which is greater than the density permitted by Applicable Laws for general office use tenants in the Building and Comparable Buildings, and (iii) Tenant shall be solely responsible (including all costs and expenses relating thereto) for any breach by Authorised Users required modifications, upgrades or other equipment or devices to appropriately support such increased occupancy density in accordance with Section 6.2, below, and any such modifications or other work or installations shall otherwise be subject to the terms of Article 8 of this Lease. Tenant further covenants and agrees that Tenant shall not use, or suffer or permit any of person or persons to use, the Premises or any part thereof for any use or purpose contrary to the provisions of this Licencethe Rules and Regulations set forth in Exhibit D, including but not limited to attached hereto, or in violation of the provisions set out below. b) Authorised Users may not: i) Remove or alter laws of the author’s name(s) United States of America, the State of California, or the publisher’s copyright notices ordinances, regulations or requirements of the local municipal or county governing body or other means lawful authorities having jurisdiction over the Project) including, without limitation, any such laws, ordinances, regulations or requirements relating to hazardous materials or substances, as those terms are defined by applicable laws now or hereafter in effect; provided, however, Landlord shall not enforce, change or modify the Rules and Regulations in a discriminatory manner and Landlord agrees that the Rules and Regulations shall not be unreasonably modified or enforced in a manner which will unreasonably interfere with the normal and customary conduct of identification Tenant’s business. Tenant shall not do or permit anything to be done in or about the Premises which will in any and all disclaimers as they appear in way damage the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part reputation of the Licensed Materials Project or obstruct or interfere with the rights of other tenants or occupants of the Building, or injure or annoy them or use or allow the Premises to be used for any purpose other than that permitted by this Licence; iii) Prepare derivative works improper, unlawful or downloadobjectionable purpose, mount nor shall Tenant cause, maintain or distribute permit any part nuisance in, on or about the Premises. As of the Licensed Material on any electronic system date of this Lease, Landlord hereby represents that there are no existing recorded easements, covenants, conditions, or networkrestrictions affecting the Project with which Tenant is required to comply. Notwithstanding the foregoing, including without limitation Tenant shall comply with, and Tenant’s rights and obligations under the Internet Lease and the World Wide Web, other than by the LicenseeTenant’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyonePremises shall be subject and subordinate to, all recorded easements, covenants, conditions, and restrictions (collectively, the “CC&Rs”) hereafter affecting the Project, provided that Landlord shall not enter into any recorded easements, covenants, conditions, or transmit any part of restrictions affecting the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of Project after the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination date of this Licence Lease which prevents Tenant from using, or unreasonably interferes with Tenant’s use of or access to, the Premises for any reasonthe Permitted Use, or otherwise materially adversely affects Tenant’s rights under this Lease.

Prohibited Uses. (a) The Licensee Notwithstanding any other provision of this Lease, Tenant shall not use reasonable efforts to ensure that the Authorised Users are aware Premises or the Building, or any part thereof, or suffer or permit the use or occupancy of the prohibitions on Premises or the Building or any part thereof by any of the Tenant Parties (i) in a manner which violates any of the covenants, agreements, terms, provisions and conditions of this Lease; (ii) for any unlawful purposes or in any unlawful manner; (iii) which, in the reasonable good faith judgment of Landlord (taking into account the use of the Licensed Materials set out in this Licence Building as a combination laboratory, research and development and office building and the Licensee Permitted Uses) shall use reasonable endeavours to ensure that its Authorised Users do not breach (a) impair the prohibitions set out in this Licence in respect of their access to and use appearance or reputation of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users Building; (b) impair, interfere with or otherwise diminish the quality of any of the Building services, or the use of any of the Common Areas; (c) occasion discomfort, inconvenience or annoyance in any material respect, or cause any injury or damage to any other tenants or occupants of the Building or their property; or (d) cause harmful air emissions, laboratory odors or noises or any unusual or other objectionable odors, noises or emissions to emanate from the Premises taking into account the use of the Building as a combination laboratory, research and development and office building and the Permitted Uses); (iv) in a manner which is materially inconsistent with the operation and/or maintenance of the Building as a first-class combination office, research, development and laboratory facility; (v) [intentionally omitted]; or (vi) in a manner which shall increase such insurance rates on the Building or on property located therein over that applicable when Tenant first took occupancy of the Premises hereunder unless Tenant pays such increase within thirty (30) days after demand therefor from time to time. From and after the Execution Date, Landlord shall include substantially similar provisions of this Licence, including but in any other leases at the Building and shall not limited enforce such provisions in a discriminatory manner. (b) With respect to the provisions set out below. b) Authorised Users may use and occupancy of the Premises and the Common Areas, Tenant will not: : (i) Remove place or alter the author’s name(s) or the publisher’s copyright notices maintain any signage (except as set forth in Section 12.2 below), trash, refuse or other means articles in any vestibule or entry of identification the Premises, on the footwalks or corridors adjacent thereto or elsewhere on the exterior of the Premises, nor obstruct any driveway, corridor, footwalk, parking area, mall or any and all disclaimers as they appear in the Licensed Materials; other Common Areas; (ii) Systematically make print permit undue accumulations of or electronic copies burn garbage, trash, rubbish or other refuse within or without the Premises; (iii) permit the parking of multiple extracts vehicles so as to interfere with the use of any driveway, corridor, footwalk, parking area, or make multiple copies other Common Areas; (iv) receive or ship articles of any kind outside of those areas reasonably designated by Landlord; (v) conduct or permit to be conducted any auction, going out of business sale, bankruptcy sale (unless directed by court order), or other similar type sale in or connected with the Premises; (vi) use the name of Landlord, or any of Landlord’s affiliates in any publicity, promotion, trailer, press release, advertising, printed, or display materials without Landlord’s prior written consent, which shall not be unreasonably withheld, conditioned or delayed; or (vii) except in connection with Alterations (hereinafter defined) approved by Landlord or otherwise not requiring Landlord’s approval, cause or permit any hole to be drilled or made in any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)Building. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee Tenant shall not use the Premises or allow the Premises to be used for any illegal purpose, or so as to create waste, or constitute a private or public nuisance. Tenant shall use reasonable efforts to ensure that maintain cooperative relations with Landlord and the Authorised Users are aware occupants of neighboring buildings in the vicinity of the prohibitions on Property. Such cooperation shall include, as reasonably requested by Landlord (a) responding to complaints regarding operational issues (i.e., lighting, parking, noise, etc.), (b) designating a representative to handle any issues that may arise, and (c) advising Tenant’s employees regarding issues of concern to Tenant’s neighbors. Tenant shall not place any loads upon the floors, walls, or ceiling that endanger the structure, or overload existing electrical or other mechanical systems. Tenant shall not use of any machinery or equipment which causes any substantial noise or vibration. Tenant shall not engage in any action or inaction that (i) jeopardizes the Licensed Materials set out Building’s LEED or Energy Star ratings, or (ii) compromises Landlord’s sustainability goals for the Building as communicated in this Licence and the Licensee shall use reasonable endeavours writing to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed MaterialsTenant. The Licensee No waste materials or refuse shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited dumped upon or permitted to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of remain upon any part of the Licensed Materials Premises or outside of the Premises except in trash containers placed inside exterior enclosures designated by Landlord for that purpose or inside of the Premises where approved by Landlord. No materials, supplies, equipment, finished products or semi-finished products, raw materials or articles of any nature shall be stored upon or permitted to remain outside the Premises or on any portion of the Common Area unless otherwise approved by Landlord in its reasonable discretion. No loudspeaker or other device, system or apparatus which can be heard outside the Premises shall be used in or at the Premises without the prior written consent of Landlord. No explosives or firearms shall be brought into the Premises. Landlord shall have the right to enter and conduct an inspection of the Premises, at any reasonable time and upon reasonable advance notice, to determine whether Tenant is complying with the terms of this Section 7.2. In the event such inspection identifies any deficiencies in Tenant’s compliance with the terms of this Section 7.2, Tenant shall promptly correct such deficiency and shall reimburse Landlord within ten (10) days after written demand as Additional Rent for any purpose other than that permitted reasonable third-party costs incurred by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved Landlord in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)connection with such inspection. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. (a) The Licensee Notwithstanding any other provision of this Lease, Tenant shall not use reasonable efforts to ensure that the Authorised Users are aware Premises or the Building, or any part thereof, or suffer or permit the use or occupancy of the prohibitions on Premises or the Building or any part thereof by Tenant, its Portfolio Companies, and/or their agents, servants, employees, consultants, contractors, subcontractors, licensees and/or subtenants (collectively with Tenant, the “Tenant Parties”) (i) in a manner which would violate any of the covenants, agreements, terms, provisions and conditions of this Lease or otherwise applicable to or binding upon the Premises; (ii) for any unlawful purposes or in any unlawful manner; (iii) which, in the reasonable judgment of Landlord (taking into account the use of the Licensed Materials set out in this Licence Building as a combination office and retail building and the Licensee Permitted Uses) shall use reasonable endeavours to ensure that its Authorised Users do not breach (a) impair the prohibitions set out in this Licence in respect of their access to and use appearance or reputation of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users Building; (b) impair, interfere with or otherwise diminish the quality of any of the provisions Building services or the proper and economic heating, cleaning, ventilating, air conditioning or other servicing of this Licencethe Building or Premises, including but not limited or the use or occupancy of any of the Common Areas; (c) occasion discomfort, inconvenience or annoyance in any material respect, or cause any injury or damage to any occupants of the Premises or other tenants or occupants of the Building or their property; or (d) cause harmful air emissions or any unusual or other objectionable odors, noises or emissions to emanate from the Premises; (iv) in a manner which is inconsistent with the operation and/or maintenance of the Building as a first-class combination office and retail facility; (v) for any fermentation processes whatsoever; or (vi) in a manner which shall increase such insurance rates on the Building or on property located therein over that applicable when Tenant first took occupancy of the Premises hereunder. (b) With respect to the provisions set out below. b) Authorised Users may use and occupancy of the Premises and the Common Areas, Tenant will not: : (i) Remove place or alter the author’s name(s) or the publisher’s copyright notices maintain any signage (except as permitted by Section 12 below), trash, refuse or other means articles in any vestibule or entry of identification the Premises, on the footwalks or corridors adjacent thereto or elsewhere on the exterior of the Premises, nor obstruct any driveway, corridor, footwalk, parking area, mall or any and all disclaimers as they appear in the Licensed Materials; other Common Areas; (ii) Systematically make print permit undue accumulations of or electronic copies burn garbage, trash, rubbish or other refuse within or without the Premises; (iii) permit the parking of multiple extracts vehicles so as to interfere with the use of any driveway, corridor, footwalk, parking area, or make multiple copies other Common Areas; (iv) receive or ship articles of any kind outside of those areas reasonably designated by Landlord; (v) conduct or permit to be conducted any auction, going out of business sale, bankruptcy sale (unless directed by court order), or other similar type sale in or connected with the Premises; (vi) use the name of the Building, the Property, Landlord, or any of Landlord’s affiliates or subsidiaries or any photograph, film, drawing, or other depiction or representation of the Building and/or the Property or any part thereof, which contains signage or distinctive architectural characteristics that cause the scene photographed, filmed, drawn, depicted, or represented to be identifiable as being the Building and/or the Property, in any publicity, promotion, trailer, press release, advertising, printed, or display materials without Landlord’s prior written consent; or (vii) except in connection with Tenant’s Work and/or Alterations (hereinafter defined) approved by Landlord, cause or permit any hole to be drilled or made in any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)Building. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. Tenant shall not use, or suffer or permit the use of, or suffer or permit anything to be done in or anything to be brought into or kept in, the Demised Premises or any part thereof (i) which would violate any of the covenants, agreements, terms, provisions and conditions of this Lease, (ii) for any unlawful purposes or in any unlawful manner, or (iii) which, in the reasonable judgment of Landlord shall in any way (a) The Licensee shall use reasonable efforts impair or tend to ensure that impair the Authorised Users are aware appearance or reputation of the prohibitions on Building, (b) impair or interfere with or tend to impair or interfere with any of the Building services or the proper and economic heating, cleaning, air conditioning or other servicing of the Building or Demised Premises, or with the use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part areas of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyoneBuilding, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior occasion discomfort, inconvenience or annoyance to carrying out or attempting to carry out any of the foregoing usesother tenants or occupants of the Building, whether through the transmission of noise or odors or otherwise. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5Without limiting the generality of the foregoing, no food shall be prepared, excepting occasional catered activities in the normal course of business, for consumption on or about the Demised Premises; no intoxicating liquors or alcoholic beverages shall be sold on or about the Demised Premises; no lottery tickets (even where the sale of such tickets is not illegal) shall continue be sold and no gambling, betting or wagering shall otherwise be permitted on or about the Demised Premises; no loitering shall be permitted in or about the Demised Premises; and no loading or unloading of supplies or other material to apply after termination or from the Demised Premises shall be permitted on the Land except at times and in locations to be designated by Landlord. The Demised Premises shall be maintained in a sanitary condition, and all kept free of this Licence for any reasonrodents and vermin. All trash and rubbish shall be suitably stored in the Demised Premises or other locations designated by Landlord from time to time.

Prohibited Uses. aTenant further covenants and agrees that it shall not use, or suffer or permit any person or persons to use, the Premises or any part thereof for any use or purpose contrary to the provisions of Exhibit D, attached hereto, or in violation of the laws of the United States of America, the State of California, or the ordinances, regulations or requirements of the local municipal or county governing body or other lawful authorities having jurisdiction over the Building; provided however that Landlord agrees that the Rules and Regulations shall not be (i) The Licensee modified or enforced in any way by Landlord so as to interfere with the Permitted Use, or (ii) discriminatorily modified or enforced against Tenant. Landlord agrees that nothing in the Rules and Regulations of the Building shall be used to prohibit or unreasonably interfere with the conduct of any business from the Premises which Tenant is permitted to conduct. In the event any other tenant or occupant of the Building fails to comply with the Rules and Regulations, and 804296.08/LAH4321-047/10-7-08/nng/law -▇▇- ▇▇▇▇▇ ▇▇▇▇ ▇▇▇▇▇[▇▇▇▇▇ ▇▇▇▇ Lease] such non-compliance unreasonably and materially interferes with Tenant's use of the Premises, Landlord shall use reasonable efforts to ensure that cause such other tenants and/or occupants to comply with the Authorised Users are aware of the prohibitions on the use of the Licensed Materials set out in this Licence Rules and the Licensee Regulations. Tenant shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to comply with all recorded covenants, conditions, and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users of any of restrictions, and the provisions of this Licenceall ground or underlying leases, including but now or hereafter affecting the Real Property which have been provided by Landlord to Tenant in writing, and shall not limited at any time use or occupy or allow any person to use or occupy the Premises or the Building or do or permit anything to be done or kept in the Premises or the Building in any manner which: (i) violates any certificate of occupancy in force for the Premises or the Building; (ii) causes or is likely to cause damage to the provisions set out below. b) Authorised Users may not: i) Remove Real Property, the Building, the Premises or alter the author’s name(s) or the publisher’s copyright notices any equipment, facilities or other means systems therein; (iii) other than conducting normal banking operations from its Premises, results in repeated demonstrations, bomb threats or other events which require evacuation of identification the Building or any otherwise disrupt the use, occupancy or quiet enjoyment of the Building by other tenants and all disclaimers as they appear occupants; or (iv) materially interferes with the transmission or reception of microwave, television, radio or other communications signals by antennae located on the roof of the Building or elsewhere in the Licensed Materials; ii) Systematically make print Building. Tenant, at Tenant's expense, shall comply with all laws, rules, orders, ordinances, directions, regulations, and requirements of federal, state, county and municipal authorities, now in force or electronic copies of multiple extracts which may hereafter be in force, which shall impose any duty or make multiple copies of any part requirement relating to the use, occupation or alteration of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)Premises. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee uses prohibited under this Lease shall use reasonable efforts to ensure that the Authorised Users are aware of the prohibitions on the include, without limitation, use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect Premises or a portion thereof for (i) offices of their access to and use any agency or bureau of the Licensed Materials. The Licensee shall be liable for United States or any breach by Authorised Users state or political subdivision thereof, unless Landlord has agreed to permit such uses within other portions of the office component of the Project; (ii) offices or agencies of any foreign governmental or political subdivision thereof, unless Landlord has agreed to permit such uses within other portions of the provisions office component of this Licence, including but not limited to the provisions set out below. bProject; (iii) Authorised Users may not: ioffices of any health care professionals or service organization; (iv) Remove or alter the author’s name(s) or the publisher’s copyright notices schools or other means of identification training facilities which are not ancillary to corporate, executive or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; professional office use; (v) Alter, edit, abridge retail or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials restaurant uses; and (whether in amended or unamended form) into any other work vi) make any Commercial Use of uses prohibited under the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone788287.02/WLA 375755-00007/7-26-18/mjh/ejw -19- C▇▇▇▇▇▇ HIGHLINE 1173, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email 1167 & 1▇▇▇ ▇▇▇▇▇▇▇ ▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) ▇ Roku, Inc. Underlying Documents. Tenant's use shall continue not result in an occupancy density for the Premises which is greater than the density permitted by Applicable Laws and zoning requirements, and further provided that Landlord shall not be obligated to apply after termination make any changes to the Base Building or Common Areas to accommodate Tenant's occupancy density. Tenant further covenants and agrees that it shall not use, or suffer or permit any person or persons to use, the Premises or any part thereof for any use or purpose contrary to the rules and regulations attached to this Lease as Exhibit D ("Rules and Regulations"), provided, however, Landlord shall not enforce, change or modify the Rules and Regulations in a discriminatory manner and Landlord agrees that the Rules and Regulations shall not be unreasonably modified or enforced in a manner which will unreasonably interfere with the normal and customary conduct of Tenant's business. In the event of any conflict between the Rules and Regulations and the other provisions of this Licence Lease, the other provisions of this Lease shall control. Tenant shall not do or permit anything to be done in or about the Premises which will in any material way obstruct or interfere with the rights of other tenants or occupants of the Project, or allow the Premises to be used for any reasonunlawful purpose, nor shall Tenant cause, maintain or permit any nuisance in, on or about the Premises.

Prohibited Uses. Tenant shall not use the Premises for any use other than the Permitted Use. Tenant shall not use or allow the Premises to be used for any unlawful purpose. Tenant shall not commit or allow to be committed (provided any acts or omissions of Landlord shall not be deemed to have been “allowed” by Tenant) nuisance or waste at or outside the Premises and shall take all reasonable action to prevent odors, emissions, fumes, liquids or other substances or excessive noise or vibrations from escaping or extending beyond the Premises. Tenant shall not do anything at or outside the Premises, nor bring or keep anything Minnetonka, Minnesota therein, which will cancel, affect or unreasonably increase the existing rate of any insurance (provided the foregoing shall not apply so long as Tenant is using the Premises for the Permitted Use). Tenant shall not: (a) The Licensee shall keep any live animals except service animals or fish in aquariums at the Premises; or (b) use reasonable efforts to ensure that the Authorised Users are aware Premises as living quarters, sleeping quarters or for lodging purposes; (c) paint or decorate the exterior of the prohibitions on Premises; and (d) alter or modify the use exterior walls or structural portions of the Licensed Materials set out in this Licence and Building without the Licensee prior written approval of Landlord (which approval shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users of any of the provisions of this Licenceunreasonably withheld, including conditioned or delayed), including, but not limited to, the roof, roof membrane, concrete slab, foundation and bearing walls. Tenant shall not, without the express written permission of Landlord, conduct, or permit to the provisions set be conducted, any auction, fire, bankruptcy, “going out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices of business” or other means of identification distress sale at or outside the Premises, whether said auction be voluntary, involuntary, pursuant to any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission assignment for the Authorised User payment of creditors or pursuant to do so; v) Alter, edit, abridge any bankruptcy or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)insolvency proceeding. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. (a) The Licensee Tenant shall not cause, suffer or permit the Premises or any part thereof to be used at any time during the Term for any of the following sales, businesses or activities: (i) any retail or wholesale sales activities; (ii) any auction; (iii) any vending machines or other coin operated machines, entertainment or games machines or any other mechanical or electrical serving or dispensing machines or devices whatsoever or the sale or supply of food or beverages to the general public (which for clarity excludes the sale or supply of food or beverages such as are routinely served in office premises) unless expressly permitted in writing by Landlord, acting reasonably. Notwithstanding the foregoing, Tenant shall be permitted to have up to two (2) food and beverage vending machines for use reasonable efforts by Tenant’s employees; (iv) any sale of tickets for theatre or other entertainment events or lottery tickets; (v) any use which would result in people waiting in Common Facilities to ensure enter the Premises or any other type of business or business practice which would, in the sole opinion of Landlord, acting reasonably, tend to lower the character or image of the Project or any portion thereof; (vi) a call centre; (vii) a use which will be incompatible with the uses of other tenants of the Project, in the sole discretion of Landlord, acting reasonably (provided that the Authorised Users are aware foregoing shall not prohibit the Tenant from carrying out the permitted use expressly set out under subsection 1(i) of the prohibitions this Lease), or will be more burdensome on the Project, in terms of parking requirements or any other factor, than the permitted use of the Licensed Materials set out Premises by Tenant; (viii) any use which will result in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not a breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users of any of the other provisions of this Licence, including but not limited Lease; (ix) a school or training centre of any kind; or (x) any use which will: (I) result in an actual or threatened cancellation of any policy of insurance of Landlord or others on or related to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification Project or any and all disclaimers as they appear part or contents thereof; or (II) be prohibited by any policy of insurance of Landlord or any others in force from time to time in respect of the Licensed Materials; ii) Systematically make print Project or electronic copies any part or contents thereof. The inclusion of multiple extracts the foregoing provisions of this Section 8.5 shall not be deemed to be a covenant, representation or make multiple copies warranty of Landlord that any of the foregoing activities will not be authorized by Landlord to be conducted on any part of the Licensed Materials for any purpose other than that permitted by this Licence;Project. iii(b) Prepare derivative works or downloadNotwithstanding anything contained in the foregoing to the contrary, mount or distribute any part so long as the Tenant in actual physical occupancy of substantially the whole of the Licensed Material on any electronic system or network, including without limitation Premises for the Internet active and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The diligent conduct of business therefrom is Primerica Life Insurance Company of BiologistsCanada and/or a Permitted Transferee, except where expressly permitted under this Licence; iv) Sell the use of portions of the Premises for handling telephone inquiries and communications between, among and regarding employees, clients, agents or resell the Licensed Materials unless The Company of Biologists has given prior written permission prospective clients or agents and/or for the Authorised User to do so; v) Alterinternal training of employees, editclients, abridge agents or otherwise modify the Licensed Materials prospective clients or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use agents, shall not constitute a breach of the Licensed Material provisions of subsections 8.5(a)(vi) and 8.5(a)(ix) above provided that: (in whole or in part); or viii) provide access to and/or permit use the live load for the floor of the Licensed Content by anyonePremises upon which such activities are being conducted does not exceed 100 lbs. (75 live, or transmit any part of the Licensed Material (other than Metadata▇▇ ▇▇▇▇) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇ ▇▇▇▇▇▇ ▇▇▇▇; (▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇) in Landlord’s determination, acting reasonably, such activities do not overburden the Common Facilities (including the Parking Facilities ) or base Building systems serving the Premises; and (iii) Tenant shall be responsible for any Excess Costs which result from such activities in accordance with the applicable provisions of this Lease. (c) For greater certainty, Landlord acknowledges that Tenant’s use of portions of the Premises for handling telephone inquiries and communications between, among and regarding employees, clients, agents or prospective clients or agents and/or for the internal training of employees, clients, agents or prospective clients or agents as conducted within the Premises as at the date hereof, i.e. for minor call centre and training purposes, is in accordance with the provisions of this Section 8.5 and does not breach the provisions hereof. (d) This clause 5Landlord hereby acknowledges to the best of its information, knowledge and belief, without due inquiry, that the use of the Premises by Primerica Life Insurance Company of Canada for general business corporate, administrative, sales/marketing, training and support offices will not violate the provisions of subsection 8.5(a)(x) shall continue to apply after termination of this Licence for any reasonabove.

Prohibited Uses. a) The Licensee TENANT shall not use reasonable efforts to ensure that the Authorised Users are aware of the prohibitions on the use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable said Premises for any breach by Authorised Users of any of the provisions of this Licence, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose use other than that permitted by this Licence; iii) Prepare derivative works or downloadwhich is specified in the Lease, mount or distribute and shall not permit them to be used, for any part other purpose, without first obtaining the written consent of LANDLORD. TENANT shall promptly and continuously comply with all laws, orders, and regulations of the Licensed Material on any electronic system or networkState, including without limitation County and City, affecting the Internet use, occupation, safety and cleanliness of the Premises and the World Wide Webequipment of TENANT . TENANT may not display or sell items or allow carts, other than by the Licensee’s Secure Network approved in advance by The Company of Biologistsportable signs, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials devices or any other objects to be stored or to remain outside the exterior walls and permanent doorways of the Premises. TENANT further agrees not to install any exterior lighting, amplifiers or similar devices or use in or about the Premises any advertising medium which may be heard or seen outside the Premises, such as flashing lights, searchlights, loudspeakers, phonographs or radio broadcasts. TENANT shall not do or permit anything to be done in or about the Premises nor bring or keep anything therein which will in any way increase the existing rate or affect any fire or other insurance upon the Premises or the Building or any of its contents, nor shall TENANT sell or permit any articles to be kept, used or sold in or about the Premises, which may be prohibited by a standard form policy of fire insurance. If LANDLORD’S insurance premium is increased as a result of TENANT ’S business operation, TENANT agrees to pay said increase. In the event Premises represent a section of a larger Building, TENANT shall not do or permit anything to be done in or about the Premises which will in any way obstruct or interfere with the rights of other tenants or occupants of the Building of which the Premises may be a part of them or injure or annoy them, or use or allow the Premises to be used for any purpose whatsoever unlawful or incorporate objectionable purpose, nor shall TENANT cause, maintain or permit any part nuisance in, on, or about the Premises. TENANT shall not commit or allow to be committed any waste in or upon Premises. TENANT shall keep the Premises in a clean and wholesome condition, free of any Licensed Materials (whether in amended objectionable noises, odors or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)nuisances. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. Lessee agrees at all times to comply with the following: (a) The Licensee Lessee shall at no time use, or permit the use reasonable efforts of, the Leased Premises in a manner that is contrary to ensure that the Authorised Users are aware of the prohibitions on applicable federal, state, or local laws, ordinances, rules, or regulations, which shall include, but not be limited to, applicable Federal Aviation Administration (“FAA”) rules and regulations and applicable regulations for the use of the Licensed Materials set out Airport as may from time to time be promulgated by MDC or City; (b) Lessee shall not permit any permanent, unshielded light or illumination source to cause glare as viewed from any street, adjacent properties or operating aircraft; (c) Lessee shall not cause or permit the burial or storage above ground on the Leased Premises of any hazardous waste or materials, as defined by federal or state law, except in this Licence accordance with applicable federal, state, or local laws, ordinances, regulations and rules, as may be adopted or amended from time to time; (d) Lessee shall not cause or permit any use or activity on the Licensee Leased Premises that may create a hazardous condition for aircraft operating at the Airport; (e) Lessee shall use reasonable endeavours not allow the Leased Premises to ensure that be used for parking of motor vehicles, motorcycles, or motor driven equipment by anyone other than customers, employees, or contractors of Lessee except as may be authorized by the Director of Airports, with all such parking being limited to areas designated by the Department of Airports for such parking. Lessee shall not be in default for the improper parking of vehicles over which neither Lessee nor any of its Authorised Users do sublessees, customers, employees, or contractors have any control; and (f) Lessee shall not breach operate, nor permit the prohibitions set out in this Licence in respect operation of, a car rental business from the Leased Premises, unless the Lessee or the operator of their access said car rental business has executed a car rental concession or permit agreement with MDC or City; and (g) Lessee shall not allow airline passenger operations to and use of be conducted on the Licensed MaterialsLeased Premises. The Licensee Leased Premises shall not be liable used for any breach by Authorised Users use that is disreputable or creates extraordinary fire hazards or results in an increased rate of insurance on the Leased Premises or its contents or the storage of any hazardous materials or substances. If, because of an act on the party of Lessee, the rate of insurance on the Leased Premises, its facilities or its contents increases, Lessee shall pay to Landlord the amount of such increase on demand, and acceptance of such payment shall not constitute a waiver of any of Landlord’s other rights. Lessee shall conduct its business and control each other Lessee party or agent, so as not to create any nuisance or interfere with other Lessees or Landlord in its management of the provisions of this LicenceLeased Premises, including but not limited its facilities or contents. Subject to Landlord’s reasonable security measures and the Rules and Regulations described in Article 17.06, Lessee and its agents and employees will have access to the provisions set out belowLeased Premises 24 hours per day, 7 days per week. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. Tenant shall not use, or suffer or permit the use of, or suffer or permit anything to be done in or anything to be brought into or kept in, the Demised Premises or any part thereof (i) which would violate any of the covenants, agreements, terms, provisions and conditions of this Lease, (ii) for any unlawful purposes or in any unlawful manner, or (iii) which, in the reasonable judgment of Landlord shall in any way (a) The Licensee shall use reasonable efforts impair or tend to ensure that impair the Authorised Users are aware appearance or reputation of the prohibitions on Building, (b) impair or interfere with or tend to impair or interfere with any of the Building services or the proper and economic heating, cleaning, air conditioning or other servicing of the Building or with the use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part areas of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyoneBuilding, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior occasion discomfort, inconvenience or annoyance to carrying out or attempting to carry out any of the foregoing usesother tenants or occupants of the Building, whether through the transmission of noise or odors or otherwise. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5Without limiting the generality of the foregoing, no food shall be prepared or served for consumption by the general public on or about the Demised Premises; no intoxicating liquors or alcoholic beverages shall be sold or otherwise permitted on or about the Demised Premises; no lottery tickets (even where the sale of such tickets is not illegal) shall continue be sold and no gambling, betting or wagering shall otherwise be permitted on or about the Demised Premises; no machinery shall be operated in the Demised Premises if such operation involves vibratory motion of any kind; no loitering shall be permitted on or about the Demised Premises; and no loading or unloading of supplies or other material to apply after termination or from the Demised Premises shall be permitted on the Land except at times and in locations to be designated by Landlord. The Demised Premises shall be maintained in a sanitary condition, and kept free of this Licence for any reasonrodents and vermin. All trash and rubbish shall be suitably stored in the Demised Premises or other locations designated by Landlord from time to time.

Prohibited Uses. a) The Licensee Tenant and Tenant’s agents shall use reasonable efforts not commit or suffer to ensure that be committed any waste upon the Authorised Users are aware Premises. Tenant and Tenant’s agents shall not do or permit anything to be done in or about the Premises, Building, Project or Common Area which will in any way obstruct or interfere with the rights of any other tenants of the prohibitions on the use Building or Project, other authorized users of the Licensed Materials set out in Common Area, or occupants of neighboring property, or injure them. Tenant shall not conduct or permit any auction or sale open to the public to be held or conducted on or about the Premises, Building, Project or Common Area. Tenant and Tenant’s agents shall not use or allow the Premises to be used for any unlawful, or hazardous purpose or any purpose not permitted by this Licence and Lease, nor shall Tenant or Tenant’s agents cause, maintain, or permit any nuisance in, on or about the Licensee Premises, Building, Project or Common Area. Tenant shall use reasonable endeavours to ensure that its Authorised Users do not breach overload existing electrical systems or other mechanical equipment servicing the prohibitions set out in this Licence in respect of their access to and use Building, impair the efficient operation of the Licensed Materialssprinkler system or the heating, ventilation or air conditioning equipment within or servicing the Building or damage, overload or corrode the sanitary sewer system. The Licensee Tenant and Tenant’s agents shall not do or permit anything to be done in or about the Premises nor bring or keep anything in the Premises which will in any way increase the rate of any insurance upon any portion of the Project or any of its contents, or cause a cancellation of any insurance policy covering any portion of the Project or any of its contents, nor shall Tenant or Tenant’s agents keep, use or sell or permit to be kept, used or sold in or about the Premises any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance upon any portion of the Project or any of its contents is increased because of Tenant’s particular use (as distinct from normal office use or normal ancillary use) of the Premises or that of Tenant’s agents, Tenant shall pay, as Additional Rent, the full cost of such increase; provided, however this provision shall in no event be deemed to constitute a waiver of Landlord’s right to declare a default hereunder by reason of the act or conduct of Tenant or Tenant’s agents causing such increase or of any other rights or remedies of Landlord in connection therewith. Tenant and Tenant’s agents shall not place any loads upon the floor, walls or ceiling of the Premises which would endanger the Building or the structural elements thereof or of the Premises, nor place any harmful liquids in the drainage system of the Building or Common Area. No waste materials or refuse shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited dumped upon or permitted to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of remain upon any part of the Licensed Materials Project except in enclosed trash containers designated for that purpose by Landlord. No materials, supplies, equipment, finished products (or semi-finished products), raw materials, or other articles of any purpose other than that nature shall be stored upon, or be permitted by this Licence; iii) Prepare derivative works or downloadto remain on, mount or distribute any part portion of the Licensed Material on any electronic system or network, including without limitation Project outside the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)Premises. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee Tenant further covenants and agrees that Tenant shall not use, or suffer or permit any person or persons to use, the Premises or any part thereof for any use reasonable efforts or purpose contrary to ensure that the Authorised Users are aware provisions of the prohibitions on "Rules and Regulations" set forth in EXHIBIT D, attached hereto, or in violation of the laws of the United States of America, the State of Arizona, or the ordinances, regulations or requirements of the local municipal or county governing body or other lawful authorities having jurisdiction over the Project, including, without limitation, any such laws, ordinances, regulations or requirements relating to hazardous materials or substances, as those terms are defined by applicable laws now or hereafter in effect. Landlord shall not modify the Rules and Regulations without Tenant's consent, which shall not be unreasonably * Portions redacted pursuant to a request for confidential treatment filed with the Securities and Exchange Commission. withheld or delayed, and which consent shall be deemed to be granted by Tenant so long as such change shall not require Tenant to pay Additional Rent and shall not unreasonably interfere with Tenant's use of the Licensed Materials set out in this Licence Premises. Such amendment is not binding on Tenant until the tenth (10th) business day after Tenant receives written notice of the change, and the Licensee no rule shall use reasonable endeavours to ensure that its Authorised Users apply retroactively. The Rules and Regulations do not breach take precedence over the prohibitions set out specific terms and conditions of the lease. Tenant shall not do or permit anything to be done in this Licence or about the Premises which will in respect any way obstruct or interfere with the rights of their access other tenants or occupants of the Building, or injure or annoy them or use or allow the Premises to be used for any unlawful purpose, nor shall Tenant cause, maintain or permit any nuisance in, on or about the Premises. Tenant shall comply with, and Tenant's rights and obligations under the Lease and Tenant's use of the Licensed Materials. The Licensee Premises shall be liable for subject and subordinate to, all recorded easements, covenants, conditions, and restrictions now or hereafter affecting the Project, provided that any breach by Authorised Users of any of such easements, covenants, conditions, and restrictions hereafter affecting the provisions of this Licence, including but Project do not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any materially and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit unreasonably interfere with Tenant's use of the Licensed Content by anyone, or transmit Premises and do not result in any additional monetary obligation on the part of the Licensed Material (Tenant other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)minor administrative compliance costs. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee shall use reasonable efforts Notwithstanding anything to ensure that the Authorised Users are aware contrary set forth herein, so long as Tenant is open and operating Original Lease the Permitted Use set forth in Section 1.6 of the prohibitions Abstract of Lease in the Premises, and has not committed an event of default which remains uncured after issuance of required notice and expiration of applicable cure periods, Landlord shall not, directly or indirectly, lease any portion of the shopping center within two hundred (200) feet of the demising walls of the Premises to other tenants or occupants for the following purposes: a liquor store, pet shop an amusement arcade, a funeral home, a shooting gallery or gun and ammunition store, a massage parlor (excluding any nationally recognized massage tenant by way of example but not limitation, Massage Envy), or an adult book store. Tenant Restrictions No Lease Provision Original Lease Abatement No Rent shall be due commencing on the use RCD and continuing for a period of three (3) months ("Abatement Months"). (Lease, Exhibit B, Pg. B-1) Original Lease Access LL reserves the Licensed Materials set right to, at all reasonable times, by itself or its duly authorized agents, employees and contractors to go upon Original Lease and inspect the Premises and every part thereof, to enforce or carry out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users of any of the provisions of this Licencethe Lease, including but not limited at its option to make repairs, alterations and additions to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) Premises or the publisher’s copyright notices bldg of which the Premises are a part, to perform any defaulted obligation of T or for any other means proper purposes. LL also reserves the right to install or place upon, or affix to the roof and exterior walls of identification the Premises, equipment, signs, displays, antenna, cables and any other object or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies structure of any part kind, provided the same shall not materially impair the structural integrity of the Licensed Materials for any purpose other than that permitted by this Licence; iiibldg or interfere w/ T's occupancy. (Lease, Sec. 7.4(B), Pg. 15) Prepare derivative works or downloadAssignment/Sublease Consent: T may not and shall not assign the Lease, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, nor sublet all or transmit any part of the Licensed Material Premises, nor license Original Lease concessions or lease departments therein, nor pledge or encumber by mortgage or other instruments any interest in the Lease (other than Metadata"Transfer") by any means w/out first obtaining the consent of LL, which consent LL shall not unreasonably withhold condition or delay. Profit Sharing: No Lease Provision. Assignment Fee: $2,000.00 Permitted Assignment: T may assign its entire interest under the Lease or sublet the Premises to anyonea wholly owned corporation, other than an Authorised Useraffiliate, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out subsidiary or attempting to carry out any parent of the foregoing usesT or to any successor to T by purchase, merger, consolidation or reorganization ("Corporate Transfer") w/out the consent of LL. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.Recapture Rights: No Lease Provision. (Lease, Sec. 10.1, Pg. 21; Rider, Sec. R-14, Pg. Rider-4)

Prohibited Uses. (a) The Licensee Tenant shall not do or permit anything to be done in or about the Premises, nor bring or keep anything therein which will cause a cancellation of any insurance policy covering the Premises, nor shall Tenant sell or permit to be kept, used or sold in or about the Premises any articles, materials, or substances which may be prohibited by a standard form policy of fire insurance. (b) Tenant shall not use reasonable efforts the Premises or permit anything to ensure that be done in or about the Authorised Users are aware Premises which will in any way conflict with any law, statute, ordinance or governmental rule or regulation or requirement of duly constituted public authorities now in force or which may hereafter be enacted, promulgated or created. Tenant shall, at Tenant’s sole cost and expense, promptly comply with all laws, statutes, ordinances and governmental rules, regulations or requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of the prohibitions on Premises, including structural changes that relate to or affect the use. (c) Tenant shall not use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable Premises for any breach by Authorised Users sexually-oriented business activities, including, without limitation, as an adult store, strip club, or similar uses. (d) Tenant shall comply with all requirements of any recorded restrictive covenants or bylaws of any owners association affecting the provisions Premises. (e) Tenant shall not permit smoking on or within the Premises at any time. (f) Tenant shall not operate an incinerator or burn trash or garbage within the Premises, the Building, or surrounding areas. (g) Tenant shall not use the Premises or conduct any activities therein which include or cause excessive noise or which otherwise interfere with the business activities or uses of other tenants occupying other spaces within the Building in which the Premises are located. (h) Tenant shall not permit any objectionable noises or odors to emanate from the Premises; nor take any other action or engage in any activities which would constitute a nuisance or would disturb or endanger other tenants of in the Building; nor permit any unlawful or immoral practice to be carried on or committed within the Premises. (i) Tenant shall not make any structural alterations, additions or improvements to the Premises without the prior written consent of Landlord, which consent may be withheld in Landlord’s sole and absolute discretion. (j) No pets of any kind are allowed. Because this is a commercial project, with various industrial and commercial activities, dogs and other pets are not allowed under any circumstances. Tenant shall pay Landlord a $500 fine for each violation of this Licence, including but not limited to the provisions set out belowprovision. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. (a) The Licensee Tenant shall not do or permit anything to be done in or about the Premises, nor bring or keep anything therein which will cause a cancellation of any inatrarice policy covering the Premises, nor shall Tenant sell or permit to be kept, used or sold in or about the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with these articles. (b) Tenant shall not use reasonable efforts the Premises or permit anything to ensure be done in or about the Premises which will in any way conflict with any law, statute, ordinance or governmental rule or regulation or requirement of duly constituted public authorities now in force or which may hereafter be enacted, promulgated or created. Tenant shall, at Tenant's sole cost and expense, promptly comply with all laws, statutes, ordinances and governmental rules, regulations or requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of die Premises, including structural changes that relate to or affect the Authorised Users are aware use (c) Tenant shall comply with all requirements of any recorded restrictive covenants or bylaws of any association affecting the Premises. Tenant acknowledges receipt of a copy of the prohibitions Declaration of Covenants, Conditions and Restrictions and a copy of the Bylaws of the Condominium Owners' Association affecting the Premises. (d) Tenant shall not permit smoking on the use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for Premises at any breach by Authorised Users of any of the provisions of this Licence, including but not limited to the provisions set out belowtime. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee Tenant further covenants and agrees that Tenant shall not use, or suffer or permit any person or persons to use, the Premises or any part thereof for any use reasonable efforts or purpose contrary to ensure that the Authorised Users are aware provisions of the prohibitions Rules and Regulations set forth in Exhibit E, attached hereto and incorporated herein by this reference, as the same may be amended from time to time (the “Rules and Regulations”), or in violation of any Underlying Documents or Applicable Laws, including, without limitation, any such laws, ordinances, regulations or requirements relating to hazardous materials or substances, as those terms are defined by Applicable Laws now or hereafter in effect. Tenant shall not do or permit anything to be done in or about the Premises which will damage the reputation of the Project or obstruct or interfere with the rights of other tenants or occupants of the Project, or injure or annoy them or use or allow the Premises to be used for any improper, unlawful or objectionable purpose, nor shall Tenant cause, maintain or permit any nuisance in, on or about the Premises. Tenant shall not suffer or allow any offensive or obnoxious vibration, noise, odor or other undesirable effect to emanate from the Premises, or any machine or other installation therein, or otherwise suffer or allow the same to constitute a disturbance to other tenants or occupants of the Building (acknowledging that Tenant may be using the Premises in a manner that is different from other tenants or occupants of the Building and that Tenant’s use of the Licensed Materials set out Premises for the Permitted Use will not be deemed to constitute a disturbance to such other tenants or occupants so long as Tenant is using the Premises in a manner reasonably similar to other similarly situated life science or biotech companies involved in light manufacturing in similarly situated buildings or developments, in accordance with the terms of this Licence and Lease, takes appropriate measures in its design of the Licensee shall use reasonable endeavours Premises to ensure that its Authorised Users do operations will not breach the prohibitions set out in this Licence in respect of their access unreasonably disturb other tenants or occupants, and otherwise uses commercially reasonable efforts not to and use disturb such other tenants or occupants of the Licensed MaterialsBuilding). The Licensee Tenant shall be liable for any breach by Authorised Users of any of the provisions of this Licencecomply with, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email T▇▇▇▇▇’s rights and obligations under this Lease and T▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) ’s use of the Premises shall continue to apply after termination be subject and subordinate to, all recorded easements, covenants, conditions, and restrictions now or hereafter affecting the Project. Additionally, Tenant shall cooperate fully with Landlord at all times and abide by all regulations and requirements that Landlord may reasonably prescribe for the proper functioning and protection of the HVAC, electrical, mechanical and plumbing systems. Notwithstanding the foregoing, in the event of any conflict between any Rules and Regulations and the express terms of this Licence Lease, the terms of this Lease shall control. Landlord shall provide reasonable advance written notice of any changes to the Rules and Regulations, and Landlord shall not institute any changes to the Rules and Regulations that (a) unreasonably and materially prohibit Tenant from using the Premises for any reasonthe Permitted Use, (b) directly by its terms requires payment of an additional material sum of money, and (c) are not uniformly applicable to the tenants in the Building using the Premises in a manner consistent with the Permitted Use (provided that such changes may affect Tenant or other tenants in different ways based on their use of the premises or rights granted to Tenant or such other tenant(s), and further provided that Landlord shall have the right to waive a rule or regulation for the benefit of a particular tenant or tenants).

Prohibited Uses. Tenant further covenants and agrees that Tenant shall not use, or suffer or permit any person or persons to use, the Premises or any part thereof for any use or purpose contrary to the provisions of the Rules and Regulations set forth in Exhibit D, attached hereto (provided that Tenant shall only be required to abide by and observe any changes to the Rules and Regulations made after the date of this Lease to the extent such changes (a) The Licensee shall use reasonable efforts to ensure that are applied in a non-discriminatory manner; (ii) do not create an unreasonable interference with or unreasonably prevent Tenant from using the Authorised Users are aware Premises for the Permitted Use, and (b) do not materially diminish the rights or materially increase the obligations of Tenant under this Lease), or in violation of the prohibitions laws of the United States of America, the State of California, or the ordinances, regulations or requirements of the local municipal or county governing body or other lawful authorities having jurisdiction over the Project, including, without limitation, any such laws, ordinances, regulations or requirements relating to hazardous materials or substances, as those terms are defined by Applicable Laws now or hereafter in effect. Tenant shall not do or permit anything to be done in or about the Premises which will in any way materially obstruct or interfere with the rights of other tenants or occupants of the Building, or injure or unreasonably annoy them or use or allow the Premises to be used for any unlawful purpose, nor shall Tenant cause, maintain or permit any nuisance in, on or about the Premises. Tenant shall comply with, and Tenant’s rights and obligations under the Lease and Tenant’s use of the Licensed Materials set out in Premises shall be subject and subordinate to, all easements, covenants, conditions, and restrictions affecting the Project which are first recorded after the date of this Licence Lease; provided, however, any such instrument shall not (and the Licensee shall could not by its terms) materially and adversely affect Tenant’s use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use or occupancy of the Licensed Materials. The Licensee Premises, increase any obligations or decrease any rights of Tenant hereunder, nor shall be liable for any breach by Authorised Users such instrument increase the rights or decrease the obligations of any of the provisions of this Licence, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.Landlord

Prohibited Uses. a) The Licensee Tenant and Tenant's agents shall use reasonable efforts not commit or suffer to ensure that be committed any waste upon the Authorised Users are aware Premises. Tenant and Tenant's agents shall not do or permit anything to be done in or about the Premises or Common Area which will in any way obstruct or interfere with the rights of any authorized users of the prohibitions Common Area or occupants of neighboring property, or injure or annoy them. Tenant shall not conduct or permit any auction or sale open to the public to be held or conducted on or about the Premises or Common Area. Tenant and Tenant's agents shall not use or allow the Premises to be used for any unlawful, immoral or hazardous purpose or any purpose not permitted by this Lease, nor shall Tenant or Tenant's agents cause, maintain, or permit any nuisance in, on or about the Premises. Tenant and Tenant's agents shall not do or permit anything to be done in or about the Premises or Common Area nor bring or keep anything in the Premises or Common Area which will in any way increase the rate of any insurance upon the Premises or Common Area or any part thereof or any of its contents, or cause a cancellation of any insurance policy covering the Premises or Common Area or any part thereof or any of its contents, nor shall Tenant or Tenant's agents keep, use or sell or permit to be kept, used or sold in or about the Premises any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance upon the Premises or Common Area or any part thereof or any of its contents is increased because of Tenant's particular use of the Licensed Materials set out Premises or that of Tenant's agents, Tenant shall pay, as Additional Rent, the full cost of such increase; provided however this provision shall in this Licence and the Licensee shall use reasonable endeavours no event be deemed to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect constitute a waiver of their access Landlord's right to and use declare a default hereunder by reason of the Licensed Materialsact or conduct of Tenant or Tenant's agents causing such increase or of any other rights or remedies of Landlord in connection therewith. The Licensee Tenant and Tenant's agents shall not place any loads upon the floor, walls or ceiling of the Premises which would endanger the Premises or the structural elements thereof, nor place any harmful liquids in the drainage system of the Premises. No waste materials or refuse shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited dumped upon or permitted to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of remain upon any part of the Licensed Materials Premises or Common Area except in enclosed trash containers designated for any that purpose other than that permitted by this Licence; iii) Prepare derivative works Landlord. No materials, supplies, equipment, finished products (or downloadsemi-finished products), mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.raw

Prohibited Uses. a) The Licensee Tenant further covenants and agrees that Tenant shall not use, or suffer or permit any person or persons to use, the Premises or any part thereof for any use reasonable efforts or purpose contrary to ensure that the Authorised Users are aware provisions of the prohibitions Rules and Regulations set forth in Exhibit D, attached hereto, or in violation of the laws of the United States of America, the State of California, or the ordinances, regulations or requirements of the local municipal or county governing body or other lawful authorities having jurisdiction over the Project, including, without limitation, any such laws, ordinances, regulations or requirements relating to hazardous materials or substances, as those terms are defined by applicable laws now or hereafter in effect. Tenant shall not do or permit anything to be done in or about the Premises which will in any way damage the reputation of the Project or obstruct or interfere with the rights of other tenants or occupants of the Building, or injure or annoy them or use or allow the Premises to be used for any improper, unlawful or objectionable purpose, nor shall Tenant cause, maintain or permit any nuisance in, on or about the Premises. Tenant shall comply with, and Tenant's rights and obligations under the Lease and Tenant's use of the Premises shall be subject and subordinate to, all recorded easements, covenants, conditions, and restrictions now or hereafter affecting the Project. Tenant shall not cause or permit any "Hazardous Substance," as that term is defined below, to be kept, maintained, used, stored, produced, generated or disposed of (into the sewage or waste disposal system or otherwise) on or in the Premises by Tenant or Tenant's agents, employees, contractors, invitees, assignees or sublessees, without first obtaining Landlord's written consent. Tenant shall immediately notify, and shall direct Tenant's agents, employees contractors, invitees, assignees and sublessees to immediately notify, Landlord of any incident in, on or about the Premises, the Building or the Project that would require the filing of a notice under any federal, state, local or quasi-governmental law (whether under common law, statute or otherwise), ordinance, decree, code, ruling, award, rule, regulation or guidance document now or hereafter enacted or promulgated, as amended from time to time, in any way relating to or regulating any Hazardous Substance. As used herein, "Hazardous Substance" means any substance which is toxic, ignitable, reactive, or corrosive and which is regulated by any local government, the State of California, or the United States government. "Hazardous Substance" includes any and all material or substances which are defined as "hazardous waste," "extremely hazardous waste" or a "hazardous substance" pursuant to state, federal or local governmental law. "Hazardous Substance" also includes asbestos, polychlorobiphenyls (i.e., PCB's) and petroleum. Landlord acknowledges, however, that Tenant will maintain products in the Premises which are incidental to the operation of its offices, such as photocopy supplies, secretarial supplies and limited janitorial supplies, which products contain chemicals which are categorized as Hazardous Substances. Landlord agrees that the use of such products in the Licensed Materials set out Premises in this Licence compliance with all applicable laws and in the Licensee manner in which such products are designed to be used shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for any breach a violation by Authorised Users of any of the provisions Tenant of this Licence, including but not limited to the provisions set out belowSection 5.2. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. Tenant shall not use, or permit the use of, the Leased Premises for any other, different or additional purpose that is not a Permitted Use without first obtaining the Approval of the Landlord Representative. Notwithstanding the Permitted Uses hereunder (but subject to Section 12.1(j)), Tenant agrees that it shall not (collectively, the “Prohibited Uses”): (a) The Licensee shall use reasonable efforts Create, cause, maintain or permit any public or private nuisance in, on or about the Leased Premises; provided, however, in no event will Landlord be entitled to ensure assert that a Permitted Use held in compliance with Applicable Laws constitutes a public or private nuisance; (b) Use or allow the Authorised Users are aware Leased Premises to be used for the sale or display of any pornographic material or material which is obscene under standards set forth in any Applicable Laws, or operate or allow any Person to operate in, on or about the Leased Premises any store or other facility, a principal or significant portion of the prohibitions on business of which is an “Adult Oriented Business,” as such term is defined in Section 25-2-801 of the City of Austin Municipal Code, as same may be amended from time to time during the Term, or any similar business; (c) Use or allow the Leased Premises to be used for the sale of paraphernalia or other equipment or apparatus that is used primarily in connection with the taking or use of illegal drugs; (d) Use or allow the Project Improvements or the Leased Premises to be used as a place of permanent residence by any Person, except for affordable housing required or permitted by Section 3.4(b) or as otherwise may be part of the Ancillary Development; (e) Use or permit the Leased Premises to be used for a shooting gallery, target range, vehicle repair facility, car wash facility, warehouse (but any area for the storage of goods intended to be sold or used in connection with Tenants’ operations permitted hereunder shall not be deemed to be a warehouse), convalescent care facility or mortuary, or use or permit the Leased Premises to be used for any assembly, manufacture, refining, smelting or other industrial or commercial operation or use (excluding, for the avoidance of doubt, a restaurant or other eatery in the concept of a restaurant-brewery, or “brewpub”); or (f) Use or permit the use of the Licensed Materials set out Leased Premises as a casino (or other establishment in this Licence and the Licensee shall use reasonable endeavours to ensure which gambling is permitted or games of chance are operated), a gentlemen’s club (or other establishment that its Authorised Users do not breach the prohibitions set out in this Licence in respect allows full or partial nudity), a massage parlor (provided that massage services may be offered by a licensed massage therapist as a part of their access to and use of the Licensed Materialsa health, beauty or fitness operation) or a tanning parlor. The Licensee shall be liable for any breach by Authorised Users of any of the provisions of this LicenceSection 12.2 shall inure to the benefit of, and be enforceable by Landlord and its successors and assigns. No other Person, including but not limited any guest or patron of the Leased Premises, shall have any right to enforce the prohibitions as to the provisions set out belowProhibited Uses. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee uses prohibited under this Lease shall use reasonable efforts to ensure that the Authorised Users are aware of the prohibitions on the include, without limitation, use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect Premises or a portion thereof for (i) offices of their access to and use any agency or bureau of the Licensed MaterialsUnited States or any state or political subdivision thereof; (ii) offices or agencies of any foreign governmental or political subdivision thereof; (iii) offices of any health care professionals or service organization; (iv) schools or other training facilities which are not ancillary to corporate, executive or professional office use; (v) retail use or the operation of any restaurant offering services to the public; (vi) a data or call center; or (vii) communications firms such as radio and/or television stations. The Licensee Tenant further covenants and agrees that Tenant shall be liable not use, or suffer or permit any person or persons to use, the Premises or any part thereof for any breach by Authorised Users of any of use or purpose contrary to the provisions of this Licencethe Rules and Regulations set forth in Exhibit D, including but not limited to attached hereto, or in violation of the provisions set out below. b) Authorised Users may not: i) Remove or alter laws of the author’s name(s) United States of America, the State of California, or the publisher’s copyright notices ordinances, regulations or requirements of the local municipal or county governing body or other means lawful authorities having jurisdiction over the Project) including, without limitation, any such laws, ordinances, regulations or requirements relating to Hazardous Substances. Tenant shall not do or permit anything to be done in or about the Premises which will in any way damage the reputation of identification the Project or obstruct or interfere with the rights of other tenants or occupants of the Building, or injure or annoy them or use or allow the Premises to be used for any unlawful purpose, nor shall Tenant cause, maintain or permit any nuisance in, on or about the Premises. Tenant shall comply with all recorded covenants, conditions, and all disclaimers as they appear restrictions now or hereafter affecting the Project. Except for small quantities customarily used in business offices, Tenant shall not cause or permit any Hazardous Substance to be kept, maintained, used, stored, produced, generated or disposed of (into the sewage or waste disposal system or otherwise) on or in the Licensed Materials; ii) Systematically make print Premises by Tenant or electronic copies of multiple extracts Tenant’s agents, employees, contractors, invitees, assignees or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or downloadsublessees, mount or distribute any part of the Licensed Material on any electronic system or networkwithout first obtaining Landlord’s written consent. Tenant shall immediately notify, including without limitation the Internet and the World Wide Web, other than by the Licenseeshall direct Tenant’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.agents,

Prohibited Uses. aTenant shall not use the Premises: (i) The Licensee shall use reasonable efforts to ensure that the Authorised Users are aware In violation of the prohibitions restrictive covenants described in Section 9.10 of that certain Declaration of Protective Covenants and Owners Association for Cool Springs East Side dated October 4, 1994, of record in Book 1235, page 725, Register's Office for Williamson County, Tennessee (the "Protective Covenants"), a copy of which has been provided by Landlord to Tenant, or in violation of the rules and regulations described in Section 12b hereof; (ii) In any manner that constitutes a nuisance or trespass, or will in any way violate any law, statute, ordinance or governmental rule or regulation now in force or which may hereafter be enacted or promulgated, (iii) In any manner that will adversely affect or interfere with any services required to be furnished by Landlord to Tenant, or to any other tenants or occupants of the Building or with the proper and economical rendition of any such service. (iv) In any manner that will in any way obstruct or interfere with the rights of other tenants of the Building or injure them, or use or allow the Premises to be used for any unlawful purpose, or commit or suffer to be committed any waste in, on or about the Premises; (v) In any manner which increases any insurance premiums, or makes such insurance unavailable to Landlord on the Building; provided that, in the event of an increase in Landlord's insurance premiums which results from Tenant's use of the Licensed Materials set out Premises, Landlord may elect to permit the use and charge Tenant for the increase in this Licence premiums, and Tenant's failure to pay Landlord, on demand, the amount of such increase shall be an event of default (in any action or proceeding wherein Landlord and Tenant are parties, a schedule or "make up" of rates applicable to the Building issued by the Tennessee Insurance Bureau, or other similar body fixing such fire insurance rates, shall be conclusive evidence of the facts therein stated and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to several items and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear charges in the Licensed Materialsfire insurance rates therein); ii(vi) Systematically make print In any manner that creates unusual demands for electricity, heating or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that air conditioning (except as permitted by this Licence; iiiSection 4(c) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in partbelow); or (vii) provide access For any purpose except the Permitted Use, unless consented to and/or by Landlord in writing. (viii) That shall cause or permit the use, generation, storage or disposal in or about the Premises or the Building of any substances, materials or wastes subject to regulation under Federal, State or local laws from time to time in effect concerning hazardous, toxic or radioactive materials (excluding the storage and use of normal cleaning supplies and office supplies customarily used for the Licensed Content by anyonePermitted Use, or transmit any part all of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may which shall be permitted under Appendix B (including by way of inter-library lendingwithout Landlord's consent so long as such items are stored and used in compliance with applicable environmental laws), unless Tenant shall have received Landlord's prior written consent, which Landlord may withhold or at any time revoke in its sole discretion. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. Tenant shall not use, or suffer or permit the use --------------- of. or suffer or permit anything to be done in or anything to be brought into or kept in, the Demised Premises or any part thereof (i) which would violate any of the covenants, agreements, terms, provisions and conditions of this Lease, (ii) for any unlawful purposes or in any unlawful manner. or (iii) which, in the reasonable judgment of Landlord shall in any way (a) The Licensee shall use reasonable efforts impair or tend to ensure that impair the Authorised Users are aware appearance or reputation of the prohibitions on Building, (b) impair or interfere with or tend to impair or interfere with any of the Building services or the proper and economic heating, cleaning, air conditioning or other servicing of the Building or Demised Premises, or with the use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part areas of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyoneBuilding, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior occasion discomfort, inconvenience or annoyance to carrying out or attempting to carry out any of the foregoing usesother tenants or occupants of the Building, whether through the transmission of noise or odors or otherwise. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5Without limiting the generality of the foregoing, no food shall be prepared or served for consumption on or about the Demised Premises; no intoxicating liquors or alcoholic beverages shall be sold on or about the Demised Premises; no lottery tickets (even where the sale of such tickets is not illegal) shall continue be sold and no gambling, betting or wagering shall otherwise be permitted oil or about the Demised Premises; no loitering shall be permitted in or about the Demised Premises; and no loading or unloading of supplies or other material to apply after termination or from the Demised Premises shall be permitted on the Land except at times and in locations to be designated by Landlord. The Demised Premises shall be maintained in a sanitary condition, and all kept free of this Licence for any reasonrodents and vermin. All trash and rubbish shall be suitably stored in the Demised Premises or other locations designated by Landlord from time to time.

Prohibited Uses. Lessee shall not use, or suffer or permit the use of, or suffer or permit anything to be done in or anything to be brought into or kept in the Premises or any part of the Premises (i) which would violate any covenant, agreement, term, provision or condition of this Lease, (ii) which would violate any law, ordinance, by-law, code, rule, regulation or order applicable to the Premises, (iii) for any unlawful purpose or in any unlawful manner, or (iv) which, in the reasonable judgment of Lessor shall in any way (a) The Licensee shall use reasonable efforts impair or tend to ensure that impair the Authorised Users are aware appearance or reputation of the prohibitions on Building or the use of Property, or (b) disturb the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users quiet enjoyment of any of the provisions other tenants or occupants of nearby properties, whether through the transmission of noise or odors or vibrations or otherwise; provided, however, that the Lessor agrees that the Lessee's use of the Demised Premises for the Use of the Demised Premises shall not be restricted as a result of this Licencesubsection (iv). No supplies or materials shall be stored outside of the Building. Lessee shall not bring or permit to be brought into or keep in or on the Premises or elsewhere in the Building or on the Land, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification any oil or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print toxic, hazardous, inflammable, combustible or electronic copies of multiple extracts explosive fluids, materials, chemicals or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or downloadsubstances, mount or distribute any part of the Licensed Material on any electronic system or network, (including without limitation any hazardous substances within the Internet meaning of Chapter 21E of the Massachusetts General Laws) (except such as are related to Lessee's use of the Demised Premises, provided that the same are stored and handled in a proper fashion consistent with applicable legal standards), or cause or permit any offensive odors to emanate from or permeate the World Wide WebPremises. The Demised Premises shall be maintained in a sanitary condition, other than by the Licensee’s Secure Network approved in advance by The Company and kept free of Biologists, rodents and vermin (except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User as such are related to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Lessee's Use of the Licensed Material (Demised Premises so long as such are contained, controlled and kept in whole accordance with industry practices and with applicable laws and regulations). Lessee shall suitably store all trash and rubbish in the Demised Premises or in part); or vii) provide access other locations reasonably designated by Lessor from time to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)time. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee uses prohibited under this Lease shall use reasonable efforts to ensure that the Authorised Users are aware of the prohibitions on the include, without limitation, use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect Premises or a portion thereof for (i) offices of their access to and use any agency or bureau of the Licensed MaterialsUnited States or any state or political subdivision thereof; (ii) offices or agencies of any foreign governmental or political subdivision thereof; (iii) offices of any health care professionals or service organization; (iv) schools or other training facilities which are not ancillary to corporate, executive or professional office use; (v) retail or restaurant uses; or (vi) communications firms such as radio and/or television stations. The Licensee Tenant shall not, without the prior written consent of Landlord (which consent shall not be unreasonably withheld, conditioned or delayed), allow the average occupancy density of the Premises to be in excess of reasonable occupancy densities of similar spaces, as reasonably determined by Landlord; it being agreed and acknowledged by Tenant that (i) in no event shall Tenant permit average occupancy density of the Premises to violate any governmental permit or zoning requirements or any requirements of any insurance policy affecting the Premises or the Building, and (ii) it shall be liable reasonable for Landlord to withhold its consent to any increase in average occupancy density of the Premises if such density will have a materially, adverse impact on the parking facilities of the Project. Tenant further covenants and agrees that Tenant shall not use, or suffer or permit any person or persons to use, the Premises or any part thereof for any breach by Authorised Users of any of use or purpose contrary to the provisions of this Licencethe rules and regulations set forth in Exhibit D (“Rules and Regulations”), including but attached hereto, or in violation of Applicable Laws; provided, however, Landlord shall not limited enforce, change or modify the Rules and Regulations in a discriminatory manner and Landlord agrees that the Rules and Regulations shall not be unreasonably modified or enforced in a manner which will unreasonably interfere with the normal and customary conduct of Tenant’s business. Tenant shall not do or permit anything to be done in or about the provisions set out below. b) Authorised Users may not: i) Remove or alter Premises which will in any way damage the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part reputation of the Licensed Materials Project or unreasonably obstruct or interfere with the rights of other tenants or occupants of the Building, or injure or annoy them or use or allow the Premises to be used for any purpose other than that permitted by this Licence; iii) Prepare derivative works improper, unlawful or downloadobjectionable purpose, mount nor shall Tenant cause, maintain or distribute permit any part of nuisance in, on or about the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)Premises. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. Notwithstanding any other provision of this Lease, Tenant shall not use, or suffer or permit the use or occupancy of, or suffer or permit anything to be done in or anything to be brought into or kept in or about the Premises or the Building or any part thereof (including, without limitation, any materials appliances or equipment used in the construction or other preparation of the Premises and furniture and carpeting): (i) which would violate any of the covenants, agreements, terms, provisions and conditions of this Lease or otherwise applicable to or binding upon the Premises; (ii) for any unlawful purposes or in any unlawful manner, (iii) which, in the reasonable judgment of Landlord shall in any way (a) The Licensee shall use reasonable efforts to ensure impair the appearance or reputation of the Building; (it being agreed that the Authorised Users are aware "Use of Premises" stated in the prohibitions on Lease Summary Sheet, if conducted reasonably, shall not be deemed to be any impairment) or (b) impair, interfere with or otherwise diminish the use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users quality of any of the provisions of this Licence, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) Building services or the publisher’s copyright notices proper and economic heating, cleaning, ventilating, air conditioning or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part servicing of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works Building; or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyonePremises, or transmit any part with the use or occupancy of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing usesother areas of the Building, or occasion discomfort, inconvenience or annoyance, or injury or damage to any occupants of the Premises or other tenants or occupants of the Building; or (iv) which is inconsistent with the maintenance of the Building as an office building of the first class in the quality of its maintenance, use, or occupancy.( it being agreed that the "Use of Premises" stated in the Lease Summary Sheet, if conducted reasonably, shall not be deemed to be so inconsistent). Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. dTenant shall not: (a) This clause 5) shall continue to apply after termination of this Licence use the Premises for lodging, or for any reasonimmoral or illegal purposes; (b) use the Premises to engage in the manufacture or sale of, or permit the use of spirituous, fermented, intoxicating or alcoholic beverages on the Premises; (c) use the Premises to engage in the manufacture or sale of or permit the use of, any illegal drugs on the Premises. Tenant shall not install or use any electrical or other equipment of any kind which, in the reasonable judgment of Landlord, might cause any such impairment, interference, discomfort, inconvenience, annoyance or injury.

Prohibited Uses. a) The Licensee Tenant and Tenant's agents shall not commit or suffer to be committed any waste upon the Premises. Tenant and Tenant's agents shall not do or permit anything to be done in or about the Premises which will unreasonably obstruct or interfere with the rights of any occupants of neighboring property, or injure or annoy them. Tenant shall not conduct or permit any auction or sale open to the public to be held or conducted on or about the Premises. Tenant and Tenant's agents shall not use reasonable efforts or allow the Premises to ensure that be used for any unlawful purpose or any purpose not permitted by this Lease, nor shall Tenant or Tenant's agents cause, maintain, or permit any nuisance in, on or about the Authorised Users are aware Premises. Tenant and Tenant's agents shall not do or permit anything to be done in or about the Premises nor bring or keep anything in the Premises which will cause a cancellation of any insurance policy covering the Premises or any part thereof or any of its contents, nor shall Tenant or Tenant's agents keep, use or sell or permit to be kept, used or sold in or about the Premises any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance upon the Premises or any part thereof or any of its contents is increased because of the prohibitions on acts or omissions of Tenant or Tenant's agents, Tenant shall pay, as Additional Rent, the use full cost of such increase; provided however this provision shall in no event be deemed to constitute a waiver of Landlord's right to any other rights or remedies of Landlord in connection with such increase. Tenant and Tenant's agents shall not place any loads upon the floor, walls or ceiling of the Licensed Materials set out Premises which would endanger the Premises or the structural elements thereof, nor place any harmful liquids in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use drainage system of the Licensed MaterialsPremises. The Licensee No waste materials or refuse shall be liable for dumped upon or permitted to remain upon any breach by Authorised Users part of the Premises except in enclosed trash containers. No materials, supplies, equipment, finished products (or semi-finished products), raw materials, or other articles of any nature shall be stored upon, or be permitted to remain on, any portion of the provisions Premises. Tenant shall not allow any activity which in the reasonable opinion of this LicenceLandlord is detrimental to the operation of other buildings located upon real property owned by Landlord adjacent to the Premises, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices any picketing, work stoppage, or other means concerted activity. Landlord shall have the right to require Tenant, at Tenant's own expense and within a reasonable period of identification time, to use Tenant's best efforts to terminate or control any and all disclaimers as they appear in such picketing, work stoppage or other concerted activity to the Licensed Materials; ii) Systematically make print extent necessary to eliminate any interference with the operation or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted such tenants. Failure by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User Tenant to use its best efforts to do so; v) Alter, edit, abridge so shall be a Default by Tenant. Nothing contained in this paragraph shall be construed as placing Landlord in an employer-employee relationship with any of Tenant's employees or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into with any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise employees who may be permitted under Appendix B (including by way of inter-library lending)involved in such activity. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee Sublessee shall use reasonable efforts to ensure that the Authorised Users are aware of the prohibitions on not use, or suffer or permit the use of of, or suffer or permit anything to be done in the Licensed Materials set out in this Licence and Sublease Premises or the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users of Building (i) which would violate any of the covenants, agreements, terms, provisions and conditions of this Sublease, (ii) for any unlawful purposes or in any unlawful manner, or (iii) which, in the reasonable judgment of Sublessor or Landlord shall in any material respect (a) impair or tend to impair the appearance or reputation of the Building in such a manner so as to detract from the quality of conditions at the Building as compared with other comparable buildings in the Boston University Medical Campus, (b) impair or interfere with any of the Building services or the proper and economic heating, cleaning, air conditioning or other servicing of the Building, or (c) occasion discomfort, inconvenience or annoyance to any of the other tenants or occupants of the Building, whether through the transmission of noise or noxious or offensive odors or otherwise. Without limiting the generality of the foregoing, no food (except in connection with customary office vending machines, coffee service facilities and lunch room facilities set forth on the Complete Plans or other plans approved by Sublessor, provided such machines and facilities are used for and by occupants of the Sublease Premises only and their guests and further provided Sublessee pays any resulting increased costs pursuant to Section 13.8 and the other applicable provisions of this LicenceSublease) shall be prepared or served for public or commercial consumption on or about the Sublease Premises; no intoxicating liquors or alcoholic beverages shall be sold or otherwise served to the general public on or about the Sublease Premises; no lottery tickets (even where the sale of such tickets is not illegal) shall be sold and no gambling, betting or wagering shall otherwise be permitted on or about the Sublease Premises; no loitering shall be permitted on or about the Sublease Premises; and no loading or unloading of supplies or other material to or from the Sublease Premises shall be permitted on the Lot except during such hours as the Building is customarily open for business. The Sublease Premises shall be maintained by Sublessee in a sanitary condition, kept free from noxious or offensive odors (including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices rodent or other means of identification or any laboratory animal odors) and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised Userkept free from vermin and, except as otherwise provided herein below, rodents. Notwithstanding anything contained herein to the contrary, Sublessee may be permitted under Appendix B maintain not more than a maximum number of five thousand (including by way of inter-library lending). c5,000) The Licensee must seek and obtain The Company of Biologists’ permission prior rodents in the Sublease Premises at any one time during the Term provided (i) Sublessee delivers to carrying out or attempting to carry out any Sublessor within thirty (30) days after the Term Commencement Date a complete report of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination number of this Licence for any reason.rodents

Prohibited Uses. Tenant shall not use, or suffer or permit the use of, or suffer or permit anything to be done in or anything to be brought into or kept in, the Demised Premises or any part thereof (i) which would violate any of the covenants, agreements, terms, provisions and conditions of this Lease, (ii) for any unlawful purposes or in any unlawful manner, or (iii) which, in the reasonable judgment of Landlord shall in any way (a) The Licensee shall use reasonable efforts impair or tend to ensure that impair the Authorised Users are aware appearance or reputation of the prohibitions on Building, (b) impair or interfere with or tend to impair or interfere with any of the Building services or the proper and economic heating, cleaning, air conditioning or other servicing of the Building or with the use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part areas of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyoneBuilding, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior occasion discomfort, inconvenience or annoyance to carrying out or attempting to carry out any of the foregoing usesother tenants or occupants of the Building, whether through the transmission of noise or odors or vibrations or dust or otherwise. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5Without limiting the generality of the foregoing, no food shall be prepared or served for consumption by the general public on or about the Demised Premises; no intoxicating liquors or alcoholic beverages shall be sold or otherwise served for consumption by the general public on or about the Demised Premises; no lottery tickets (even where the sale of such tickets is not illegal) shall continue be sold and no gambling, betting or wagering shall otherwise be permitted on or about the Demised Premises; no loitering shall be permitted on or about the Demised Premises; and no loading or unloading of supplies or other material to apply after termination or from the Demised Premises shall be permitted on the Land except at times (excluding Business Days from 7:00 to 9:30 a.m. and from 4:00 to 6:00 p.m.) and in locations to be reasonably designated by Landlord, except for the freight elevator described in Section 7.4, which Tenant may use at any time. The Demised Premises shall be maintained in a sanitary condition. Tenant shall suitably store all trash and rubbish in the Demised Premises or other locations designated by Landlord from time to time. All laboratory waste, Hazardous Materials and medical waste must be disposed of this Licence for in compliance with Section 5.3. Tenant specifically agrees that its indemnification obligations pursuant to Section 13.2 shall extend to any reasonclaim arising from the consumption of intoxicating liquors or alcoholic beverages on or about the Demised Premises.

Prohibited Uses. a) The Licensee Tenant shall not use reasonable efforts to ensure that the Authorised Users are aware of the prohibitions on or permit the use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for Demised Premises or any breach by Authorised Users of part thereof which would violate any of the provisions of this LicenceLease, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works which is in violation of Applicable Laws, or downloadin any unlawful manner, mount or distribute any part in violation of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company Certificate of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission Occupancy for the Authorised User to do so; v) AlterDemised Premises or the Building, edit, abridge and Tenant shall not suffer or otherwise modify permit the Licensed Materials Demised Premises or any part thereof to be used in any manner, or anything to be done therein or anything to be brought into or kept therein which, in the reasonable judgement of them for Landlord, shall in any purpose whatsoever way impair the character, reputation or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use appearance of the Licensed Material (in whole Building as a first rate office building, impair or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out interfere with any of the foregoing usesBuilding services or the proper and economic heating, cleaning, air-conditioning or other servicing of the Building or the Demised Premises, or impair or interfere with the use of any of the other areas of the Building by, or occasion unreasonable discomfort, inconvenience or annoyance to, any of the other tenants or occupants of the Building. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇Tenant shall not install any electrical or other equipment of any kind which, in the reasonable judgement of Landlord, might cause any such impairment, interference, discomfort, inconvenience or annoyance to Landlord or any other tenant in the Building, Tenant shall not make void or voidable any fire or liability insurance policy then in force with respect to the Building nor shall Tenant make unobtainable from reputable insurance companies authorized to do business in New York State any fire or casualty insurance with extended coverage or liability, elevator, boiler or other insurance at standard rates. Tenant shall not suffer or permit the Demised Premises to be used in a manner which would constitute a public or private nuisance or unreasonably impair, in the sole reasonable opinion of Landlord, the appearance, character or reputation of the Building.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee Tenant shall use reasonable efforts not commit or permit any Tenant Related Parties to ensure that commit any waste upon the Authorised Users are aware Premises or Common Area (or any area where Tenant places its Generators or Bloom Boxes to the extent permitted under this Lease). Tenant and Tenant Related Parties shall not do or permit anything to be done in the Premises or do or permit anything to be done by any of them in other parts of the prohibitions Building, Project or Common Area which will unreasonably obstruct or interfere with the rights of any other tenants of the Building or Project, other authorized users of the Common Area, or occupants of neighboring property, or injure or unreasonably annoy them. Tenant shall not conduct or permit any auction or sale open to the public to be held or conducted on or about the Premises, Building, Project or Common Area. Tenant and all Tenant Related Parties shall not use or allow the Premises to be used for any unlawful or hazardous purpose, nor shall Tenant or any Tenant Related Parties cause, maintain, or permit any nuisance in, on or about the Premises, Building, Project or Common Area. Tenant shall not overload existing electrical systems or other mechanical equipment servicing the Building, impair the efficient operation of the sprinkler system or the heating, ventilation or air conditioning equipment within or servicing the Building or Premises or damage, overload or corrode the sanitary sewer system. Tenant and Tenant Related Parties shall not do or permit anything to be done in or about the Premises nor bring or keep anything in the Premises which will in any way increase the rate of any insurance upon any portion of the Project or any of its contents, or cause a cancellation of any insurance policy covering any portion of the Project or any of its contents, nor shall Tenant or any Tenant Related Parties keep, use or sell or permit to be kept, used or sold in or about the Premises any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance upon any portion of the Project or any of its contents is increased because of Tenant’s particular use of the Licensed Materials set out Premises or that of any Tenant Related Parties, Tenant shall pay, as Additional Rent, the full cost of such increase; provided, however this provision shall in this Licence and the Licensee shall use reasonable endeavours no event be deemed to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect constitute a waiver of their access Landlord’s right to and use declare a default hereunder by reason of the Licensed Materialsact or conduct of Tenant or any Tenant Related Parties causing such increase or of any other rights or remedies of Landlord in connection therewith. The Licensee Tenant and Tenant Related Parties shall not place any loads upon the floor, walls or ceiling of the Premises which would endanger the Building or the structural elements thereof or of the Premises, nor place any harmful liquids in the drainage system of the Building or Common Area. No waste materials or refuse shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited dumped upon or permitted to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of remain upon any part of the Licensed Materials Project except in enclosed trash containers designated for any that purpose other than that by Landlord. Except as expressly permitted by this Licence; iii) Prepare derivative works Lease with respect to Bloom Boxes and Generators (and then subject to the provisions of Paragraphs 48 and 49 below), no materials, supplies, equipment, finished products (or downloadsemi-finished products), mount raw materials, or distribute other articles of any part nature shall be stored upon, or be permitted to remain on, any portion of the Licensed Material on any electronic system or network, including without limitation Project outside the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)Premises. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. (a) The Licensee Tenant shall use reasonable efforts not do or permit anything to ensure that be done in or about the Authorised Users are aware of Premises nor bring or keep anything therein which will in any way increase the prohibitions existing rate or affect any fire or other insurance on the use Building or any of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users contents, or cause a cancellation of any of insurance policy covering the provisions of this Licence, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials Building or any part thereof or any of its contents, nor shall Tenant sell or permit to be kept, used or sold, in or about the Premises, any articles or substances, inflammable or otherwise, which may be prohibited by a standard form policy of the insurance. (b) Tenant shall not do or permit anything to be done in or about the Premises which will in any way obstruct space or interfere with the rights of other tenants or occupants of the Building or injury or annoy them or use or allow the Premises to be used for any purpose whatsoever unlawful or incorporate objectionable purpose, nor shall Tenant cause, maintain or permit any part nuisance in or about the Premises. Tenant shall not commit or suffer to be committed any waste in or upon the Premises. (c) Tenant shall not use the Premises or permit anything to be done in or about the Premises which will in any way conflict with any law, statute, ordinance or governmental rule or regulation or requirement of duly constituted public authorities now in force or which may hereafter be enacted or promulgated. Tenant shall at its sole cost and expense promptly comply with all laws, statutes, ordinances and governmental rules, regulations or requirements now in force or which may hereafter be in force and with the requirements of any Licensed Materials (whether in amended board of fire underwriters or unamended form) into any other work vi) make any Commercial Use similar body now or hereafter constituted relating to or affecting the condition, use or occupancy of the Licensed Material (in whole Premises, excluding structural changes not relating to or in part); or vii) provide access to and/or permit affecting the condition, use or occupancy of the Licensed Content Premises not related or afforded by anyoneTenant's improvements or acts. The judgment of any court of competent jurisdiction or the admission of Tenant in any action against Tenant, whether Landlord be a party thereto or transmit not, that Tenant has violated any part law, statute, ordinance or governmental rule, regulation or requirement shall be conclusive of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except fact as otherwise may be permitted under Appendix B (including by way of inter-library lending)between Landlord and Tenant. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. In addition to the use restrictions set forth elsewhere in this Lease, Tenant will not: (a) The Licensee shall permit in or from the Premises any objectionable odor or noise or any nuisance, except for such odor and/or noise that is reasonable and customary for the operation of a brewery; (b) commit waste; (c) permit the Premises to be used for an auction, fire, bankruptcy or going out of business sale; (d) cease active conduct of Tenant’s business in the Premises for more than thirty (30) days without the prior written consent of Landlord, not to be unreasonably withheld; (e) use reasonable efforts to ensure that the Authorised Users are aware any portion of the prohibitions Premises as residential rental property; (f) engage in any trade or business consisting of the operation of, or otherwise permit the use of any portion of the Premises for, any private or commercial golf course, country club, massage parlor, hot tub facility, suntan facility, racetrack or other facility used for gambling, or any store the principal business of which is the retail carry-out sale of alcoholic beverages for consumption off premises, excluding the sale of bulk beverages brewed or otherwise produced on the Premises; (g) permit the development or holding of intangibles for sale or license; or (h) use, store, manufacture, dispose of or discharge any hazardous materials in, at or from the Premises. As used in this section, “hazardous materials” means any substances or materials the use, transportation, storage, manufacture or disposal of which is governed by laws treating the quality of the environment, and will include asbestos and petroleum products. Use of hazardous materials in accordance with law in amounts appropriate to and necessary for the use of the Licensed Materials set out in Premises permitted by this Licence Lease will be permitted. Accordingly, Tenant agrees to indemnify Landlord and hold it harmless for any costs and/or liabilities including without limitation reasonable attorneys’ fees, arising from Tenant’s release of any hazardous materials or failure to comply with applicable environmental laws. Tenant first shall obtain the Licensee shall use reasonable endeavours written consent of Landlord prior to ensure that its Authorised Users do not breach (i) expanding the prohibitions set out in this Licence in respect of their access to and use area of the Licensed Materials. The Licensee shall be liable Premises associated with the sale of alcoholic beverages for any breach by Authorised Users of any off-premises consumption beyond 5% of the provisions total square footage of this Licencethe Premises, including but (ii) expanding Tenant’s sales of alcoholic beverages for off-premises consumption beyond 10% of total sales from the Premises during any calendar year, or (iii) selling lottery tickets on the Premises. Consent is subject to Landlord’s sole and absolute discretion. Tenant shall not limited to the provisions set out below. b) Authorised Users may not: (i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or carry on any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of activity that could cause any part of the Licensed Materials Premises or the Building to be “tax-exempt use property” (as that term is used in Section 168(h) of the Internal Revenue Code) or “residential rental property” (as defined in Section 168 of the Internal Revenue Code) or (ii) use the Premises or the Building to engage in the operation of any private or commercial golf course, country club, massage parlor, hot tub facility, suntan facility, racetrack, off-track betting facility or other facility used for gambling; or any purpose other than store the principal business of which is the retail carry-out sale of alcoholic beverages for consumption off premises, excluding the sale of bulk beverages brewed or otherwise produced on the Premises, or fireworks; farming (within the meaning of Section 2032A(e)(5)(A) or (B) of the Code and the related Treasury Regulations), or any one or more of the following activities: shooting gallery, adult bookstore or facility selling or displaying obscene or pornographic books, literature or videotapes or movies (materials shall be considered “adult”, “obscene” and “pornographic” for such purposes if the same are not generally available for sale, rental or display to human persons under 18 years old because they explicitly deal with or depict human sexuality or are otherwise intended to appeal to prurient interests); any establishment that permitted provides striptease or topless entertainment; bingo or similar games of chance (excluding such games conducted by this Licence; iii) Prepare derivative works or download, mount or distribute any a charitable organization as part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in parta fundraising activity); or vii) provide access to and/or permit use of the Licensed Content by anyone, video game or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised Useramusement arcade, except as otherwise may be permitted under Appendix B (including by way an incidental part of interanother primary business; pawn shops or establishments, a primary business or service of which is cashing checks; any marijuana dispensary, so-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out called “head shop” or attempting to carry out any of the foregoing uses. Email store that sells bongs, coke spoons, r▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d▇ clips or other drug paraphernalia; a flea market; any political campaign or party office; or any illegal use (collectively, (i) This clause 5and (ii) shall continue to apply after termination in this paragraph, and all other prohibited uses set forth in the preceding paragraph of this Licence for Section 22, are referred to as the “Use Restrictions”). Any violation of the Use Restrictions shall constitute an event of default of this Lease and shall permit Landlord to immediately terminate this Lease to the extent permitted by applicable law, including any reasonminimum notice requirements thereof.

Prohibited Uses. a) The Licensee Tenant shall use reasonable efforts not cause, suffer or permit the Premises or any part thereof to ensure that be used at any time during the Authorised Users are aware Term for any of the prohibitions on following businesses or activities: any type of business or business practice which would, in the use reasonable opinion of Landlord, tend to lower the character or image of the Licensed Materials set out Project or any portion thereof; any use which in any way contravenes any restrictive covenants in leases granted by Landlord after the date hereof; Tenant covenants and agrees that it will not carry on in the Premises any business which will in any way place Landlord in breach of any such restrictive covenants and Tenant will indemnify and save Landlord harmless from and against all actions, claims, demands and costs with respect thereto; this Licence and subsection (ii) shall not be interpreted to prevent Tenant from carrying on in the Licensee shall use reasonable endeavours Premises any business to ensure that its Authorised Users do the extent expressly permitted pursuant to section 8.1 hereof; or any business or activity not breach the prohibitions set out in this Licence in respect of their access to and use compliance with all Laws. The inclusion of the Licensed Materialsforegoing provisions of this section 8.10 shall not be deemed to be a representation or warranty of Landlord that any of the foregoing activities will not be authorized by Landlord to be conducted on any part of the Project. The Licensee shall be liable for any If, in the opinion of Landlord, Tenant is in breach by Authorised Users of any of the provisions of this Licencesection 8.10, including but Tenant shall immediately discontinue such use upon Landlord's written request. Any restrictive covenants granted by the Landlord shall not limited restrict the Tenant from carrying on its business as contemplated herein and shall not result in any increase in charges to the provisions set out belowTenant pursuant to this Lease. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee shall use reasonable efforts to ensure It is agreed that the Authorised Users are aware of the prohibitions on the use of the Licensed Materials set out in this Licence and the Licensee Premises shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable used for any breach by Authorised Users of any of the provisions of this Licencefollowing uses, including but and LESSOR'S consent to such uses will not limited be provided a bar, night club, lounge, dance hall, discotheque, teenager gathering place, massage parlor, adult book store, or similar business catering to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear pornographic interests, establishments engaged in the Licensed Materials; ii) Systematically make print or electronic copies business of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or downloadselling, mount or distribute any part of the Licensed Material on any electronic system or networkdistributing, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyonedisplaying, or transmit any part of the Licensed Material (other than Metadata) by any means to anyoneoffering for sale, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇▇ clips, water pipes, bongs, coke spoons, hypodermic syringes or other paraphernalia commonly used in the use of or ingestion of illicit drugs (including, without limitations, a so-called “head shop”), bowling alley, kiosk business, firearms shooting range, bingo hall, theatre, funeral parlor, flea market, amusement or video arcade, pool or billiard hall, pawn shop, gun shop, tattoo parlor, car wash, automobile repair shop, or any business servicing motor vehicles in any respect, including, without limitation, any quick lube oil change service, tire center or gasoline or service station or facility, any carnival, amusement park or circus, hotel/motel, area for commuter parking, any use which involves the sale or display of merchandise generally offensive to the public, or any use which will in any way increase the existing rate of or affect any fire or extended coverage insurance policy upon the building of which the Premises are a part, or cause a cancellation of any insurance policy covering the building of which the Premises are a part. The foregoing list shall not be interpreted as a limitation or restriction of LESSOR'S discretion in its decision on consent to uses of the Premises by LESSEE. Notwithstanding the foregoing or anything else to the contrary contained in this lease, LESSEE is prohibited from using the Premises or any portion thereof for the sale or distribution of alcoholic beverages without the prior written consent of LESSOR. Adequate liquor liability insurance with LESSOR as an additional insured shall be a prerequisite, although not the only precondition, to LESSOR'S consent. LESSEE shall not conduct sidewalk sales, tent sales, auction sales, warehouse sales or fire sales at the Premises, or in the Common Facilities.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee Tenant shall use reasonable efforts keep the Premises free from waste and nuisance at all times. Tenant shall keep the Premises clean throughout, (including, but without limitation, floors, light fixtures and all glass). Tenant shall not, without Landlord's prior consent, locate or install or cause to ensure that the Authorised Users are aware of the prohibitions be located or installed on the use of sidewalks or service area (if any) immediately adjoining the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for Premises any breach by Authorised Users bike racks, newspaper holder stands, vending machines of any of the provisions of this Licencekind, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification mailboxes, telephone booths, “No parking” signs or any and all disclaimers as they appear in other device of a similar nature which would impede or obstruct the Licensed Materials; ii) Systematically make print sidewalk or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or downloadservice area. Tenant shall not, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@'s prior written consent, perform or fail to perform any act, keep anything within the Premises, or use the Premises for any purpose which increases the insurance premium cost or invalidates any insurance policy carried on either the Premises or on other parts of the center. If Landlord does give such written consent to Tenant, then Tenant shall be responsible, at its sole cost and expense for the amount of any increase in the casualty or liability insurance premium cost. Tenant shall not, without ▇▇▇▇▇▇▇▇▇▇'s prior written consent, conduct or permit to be conducted within the Premises any auction or bankruptcy sales nor permit any objectionable or unpleasant odors or loud noises to emanate from the Premises, nor place or permit any radio, television or other antennae, loud speaker or amplifiers, or flashing lights or searchlights on the roof or outside the Premises or where the same can be seen or heard outside the building; nor take any other action which would disturb or endanger other Tenants of the Center (if applicable) or unreasonably interfere with their use of their respective premises or the Common Area.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. (a) The Licensee Throughout the Term, Landlord shall use reasonable efforts to ensure that not further develop the Authorised Users are aware Property, other than consistent with the provisions of this Lease, and, without limiting the prohibitions on the use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee generality thereof, no such further development shall be liable for any breach by Authorised Users of any permitted if (1) the same would cause a violation of the provisions of this LicenceSection 4.8(b) hereof or Section 14.20 hereof, including but not limited or (2) the same would otherwise result in (i) an increase in the amount of any Additional Rent payable by Tenant hereunder, (ii) any other cost or expense being imposed upon Tenant or any Tenant Party, (iii) any reduction in the value of the Leased Premises to Tenant or any Tenant Party, (iv) parking or traffic flow on the provisions set out belowProperty being adversely affected from the perspective of Tenant or any Tenant Party, (v) any reduction in the function or utility of the Common Areas (or any portion thereof) from the perspective of Tenant or any Tenant Party. (b) Authorised Users may not: i) Remove Throughout the Term, Landlord shall not use, or alter permit the author’s name(s) or use of, the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials Property (or any part of them thereof) for any purpose whatsoever Prohibited Uses. The term “Prohibited Uses” shall mean (i) any use that emits an obnoxious odor, noise or incorporate sound that can be heard or smelled outside of the premises; (ii) any part use in violation of any Licensed Materials (whether in amended zoning regulations or unamended form) into any other work governmental restrictions applicable to the Property; (iii) any use that, by its nature, (even if such use is legally permissible) would result in parking or traffic flow on the Property being materially adversely affected from the perspective of Tenant or any Tenant Party; (iv) any operation primarily used as a warehouse or storage facility, assembling or manufacturing, distilling, refining, rendering, processing, smelting, agricultural or mining operations; (v) any mobile home park or sales, trailer court, labor camp, junk yard or stockyard; (vi) make any Commercial Use central laundry, dry cleaning plant or laundromat; provided, however, this prohibition shall not be applicable to on-site services oriented only to pickup and delivery by consumers; (vii) any automobile, truck, trailer or recreational vehicle sales, leasing, display, repair or body shop; (viii) any living quarters, sleeping apartments, hotel or lodging rooms; (xi) veterinary hospitals, animal raising or breeding facilities, animal boarding facilities or pet shops; (x) mortuaries or funeral homes; (xi) any establishment that sells, rents or exhibits pornographic materials; (xii) massage parlors or any form of sexually oriented business (including novelty merchandise sales); (xiii) bars, taverns or brew pubs; (xiv) flea markets, amusement or video arcades, computer game rooms, pool or billiard halls, bingo halls, dance halls, discos or night clubs; (xv) sales of paraphernalia for use with illicit drugs; (xvi) carnivals, amusement parks or circuses; (xvii) pawn shops, auction houses, second hand stores, consignment shops, army/navy surplus stores or gun shops; (xviii) gambling facilities or sports betting parlor; (xix) churches, synagogues or other places of worship; (xx) assembly halls or meeting facilities; (xxi) technical or vocational schools or any other operation primarily engaged in education or training activities; (xxii) medical clinics, abortion clinics, medical laboratories or screening facilities; (xxiii) any agency (public or private) providing health, welfare, social or human services, or (xxiv) tattoo parlors, fortune telling or spiritual readings; (xxv) facilities that collect donated goods and products; (xxvi) bowling alleys, skating rinks, archery or gun ranges, (xxvii) postal facilities, tax collectors, tag agencies, jails or detention centers, courthouses or any other form of agency dealing with civil authority. Notwithstanding the foregoing, the term "Prohibited Uses" shall not include any use which is permitted under a third party tenant lease of space in the Building which is in effect as of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)Commencement Date. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee Tenant and Tenant’s Agents shall use reasonable efforts not commit or suffer to ensure that be committed any waste upon the Authorised Users are aware Premises. Tenant and Tenant’s Agents shall not do or permit anything to be done in or about the Premises or Common Area which will in any way obstruct or interfere with the rights of any authorized users of the prohibitions Common Area or occupants of the Adjacent Parcel (or improvements thereon), or injure them. Tenant shall not conduct or permit any auction or sale open to the public to be held or conducted on or about the Premises or Common Area. Tenant and Tenant’s Agents shall not use or allow the Premises to be used for any unlawful, immoral or, except as expressly permitted by this Lease, hazardous purpose or any purpose not permitted by this Lease, nor shall Tenant or Tenant’s Agents cause, maintain, or permit any nuisance in, on or about the Premises. Tenant and Tenant’s agents shall not do or permit anything to be done in or about the Premises or Common Area nor bring or keep anything in the Premises or Common Area which will in any way increase the rate of any insurance upon any portion of the Project or any of its contents, or cause a cancellation of any insurance policy covering any portion of the Project or any of its contents, nor shall Tenant or Tenant’s Agents keep, use or sell or permit to be kept, used or sold in or about the Premises or Common Area any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance upon any portion of the Project or any of its contents is increased because of Tenant’s particular use of the Licensed Materials set out Premises or Common Area or that of Tenant’s agents, Tenant shall pay, as Additional Rent, the full cost of such increase; provided, however this provision shall in this Licence and the Licensee shall use reasonable endeavours no event be deemed to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect constitute a waiver of their access Landlord’s right to and use declare a default hereunder by reason of the Licensed Materialsact or conduct of Tenant or Tenant’s agents causing such increase or of any other rights or remedies of Landlord in connection therewith. The Licensee Tenant and Tenant’s agents shall not place any loads upon the floor, walls or ceiling of the Premises which would endanger the Building or the structural elements thereof or of the Premises, nor place any harmful liquids in the drainage system of the Building or Common Area. No waste materials or refuse shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited dumped upon or permitted to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of remain upon any part of the Licensed Materials Project except in enclosed trash containers designated for that purpose by Landlord. No materials, supplies, equipment, finished products (or semi-finished products), raw materials, or other articles of any purpose other than that nature shall be stored upon, or be permitted by this Licence; iii) Prepare derivative works or downloadto remain on, mount or distribute any part portion of the Licensed Material on any electronic system or network, including without limitation Project outside the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)Premises. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee Notwithstanding any other provision of this Lease, Tenant shall not use, or suffer or permit the use reasonable efforts or occupancy of, or suffer or permit anything to ensure that be done in or anything to be brought into or kept in or about the Authorised Users are aware premises or the Building or any part thereof (including, without limitation, any materials appliances or equipment used in the construction or other preparation of the prohibitions on the use premises and furniture and carpeting): (i) which would violate any of the Licensed Materials set out covenants, agreements, terms, provisions and conditions of this Lease or otherwise applicable to or binding upon the Premises that are in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use effect as of the Licensed Materials. The Licensee shall date of this Lease and of which Tenant has received notice prior to the execution of this Lease, including, without limitation, those covenants affecting the Franklin Industrial Park ("Park Covenants") and, subject to Article 23(h), any future rules and regulations which may be liable issued pursuant to the Park Covenants, (ii) for any breach by Authorised Users unlawful purposes or in any unlawful manner; or (iii) which, in the reasonable judgment of Landlord shall in any way impair, interfere with or otherwise diminish the quality of any of the provisions of this Licence, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) Building services or the publisher’s copyright notices proper and economic heating, cleaning, ventilating, air conditioning or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part servicing of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works Building; or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyonepremises, or transmit any part with the use or occupancy of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the other areas of the Building, or occasion discomfort, inconvenience or annoyance, or injury or damage to any occupants of the premises or other tenants or occupants of the Building. Tenant shall not install or use any electrical or other equipment of any kind which, in the reasonable judgment of Landlord, might cause any such impairment, interference, discomfort, inconvenience, annoyance or injury. Notwithstanding the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination terms of this Licence Article 5.2, Tenant shall not be deemed to have suffered or permitted an act or omission: (x) which occurs outside of the Premises, unless such act or omission was by Tenant or those for any reasonwhom Tenant is legally responsible, or (y) by Landlord or those for whom Landlord is legally responsible.

Prohibited Uses. a) The Licensee Tenant further covenants and agrees that Tenant shall not use, or suffer or permit any person or persons to use, the Premises or any part thereof for any use reasonable efforts or purpose contrary to ensure that the Authorised Users are aware provisions of the prohibitions Rules and Regulations set forth in Exhibit A, attached hereto, or in violation of the laws of the United States of America, the State of California, the ordinances, regulations or requirements of the local municipal or county governing body or other lawful authorities having jurisdiction over the Project) including, without limitation, any such laws, ordinances, regulations or requirements relating to hazardous materials or substances, as those terms are defined by applicable laws now or hereafter in effect, or any easement, license, operating agreement, declaration, restrictive covenant, or instrument recorded against the Project, including, without limitation, any covenants, conditions and restrictions affecting the Project, any reciprocal easement agreements affecting the Project, any parking licenses, and any agreements with transit agencies affecting the Project (collectively, "Underlying Documents"). A violation of the Rules and Regulations by Tenant shall be deemed a default under this Article 5. Tenant shall not do or permit anything to be done in or about the Premises which will in any way damage the reputation of the Project or obstruct or interfere with the rights of other tenants or occupants of the Building, or injure or annoy them or use or allow the Premises to be used for any improper, unlawful or objectionable purpose, nor shall Tenant cause, maintain or permit any nuisance in, on or about the Premises. Tenant shall comply with, and Tenant's rights and obligations under the Lease and Tenant's use of the Licensed Materials set out in Premises shall be subject and subordinate to, all recorded easements, covenants, conditions, and restrictions now or hereafter affecting the Project so long as any such recorded easements, covenants, conditions, and restrictions first affecting the Project after the date of this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users Lease do not breach the prohibitions set out in this Licence in respect of their access to and materially adversely affect Tenant’s possession, use or enjoyment of the Licensed Materials. The Licensee shall be liable Premises for any breach by Authorised Users of any of the provisions of this Licence, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove Permitted Use or alter the authormaterially adversely affect Tenant’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted parking rights under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)Lease. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. Tenant shall not use, or suffer or permit the use of, or suffer or permit anything to be done in or anything to be brought into or kept in, the Demised Premises or any part thereof (i) which would violate any of the covenants, agreements, terms, provisions and conditions of this Lease, (ii) for any unlawful purposes or in any unlawful manner, or (iii) which, in the reasonable judgment of Landlord shall in any way (a) The Licensee shall use reasonable efforts impair or tend to ensure that impair the Authorised Users are aware appearance or reputation of the prohibitions on Building, (b) impair or interfere with or tend to impair or interfere with any of the Building services or the proper and economic heating, cleaning, air conditioning or other servicing of the Building or with the use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part areas of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyoneBuilding, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior occasion discomfort, inconvenience or annoyance to carrying out or attempting to carry out any of the foregoing usesother tenants or occupants of the Building, whether through the transmission of noise or odors or vibrations or dust or otherwise. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5Without limiting the generality of the foregoing, no food shall be prepared or served for consumption by the general public on or about the Demised Premises; no intoxicating liquors or alcoholic beverages shall be sold or otherwise served for consumption by the general public on or about the Demised Premises; no lottery tickets (even where the sale of such tickets is not illegal) shall continue be sold and no gambling, betting or wagering shall otherwise be permitted on or about the Demised Premises; no loitering shall be permitted on or about the Demised Premises; and no loading or unloading of supplies or other material to apply after termination or from the Demised Premises shall be permitted on the Land except at times (excluding Business Days from 7:00 to 9:30 a.m. and from 4:00 to 6:00 p.m.) and in locations to be designated by Landlord. The Demised Premises shall be maintained in a sanitary condition. Tenant shall suitably store all trash and rubbish in the Demised Premises or other locations designated by Landlord from time to time. Tenant specifically agrees that its indemnification obligations pursuant to Section 13.3 shall extend to any claim arising from the consumption of this Licence for any reasonintoxicating liquors or alcoholic beverages on or about the Demised Premises.

Prohibited Uses. (a) The Licensee Notwithstanding any other provision of this Lease, Tenant shall not use reasonable efforts to ensure that the Authorised Users are aware Premises or the Building, or any part thereof, or suffer or permit the use and/or occupancy of the prohibitions on Premises or the Building or any part thereof by Tenant and/or Tenant’s agents, servants, employees, consultants, contractors, subcontractors, licensees and/or subtenants (collectively with Tenant, the “Tenant Parties”) (i) in a manner which would violate any of the covenants, agreements, terms, provisions and conditions of this Lease or otherwise applicable to or binding upon the Premises; (ii) for any unlawful purposes or in any unlawful manner; (iii) in a manner which, in the reasonable judgment of Landlord (taking into account the use of the Licensed Materials set out in this Licence Building as a combination institutional, office and retail building and the Licensee Permitted Uses) shall use reasonable endeavours to ensure that its Authorised Users do not breach (a) impair the prohibitions set out in this Licence in respect of their access to and use appearance or reputation of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users Building; (b) impair, interfere with or otherwise diminish the quality of any of the provisions of this Licence, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) Building services or the publisher’s copyright notices proper and economic heating, cleaning, ventilating, air conditioning or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part servicing of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works Building or downloadPremises, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email Common Areas; (c) occasion discomfort, inconvenience or annoyance in any material respect (and Tenant shall not install or use any electrical or other equipment of any kind which, in the reasonable judgment of Landlord, will cause any such material impairment, interference, discomfort, inconvenience, annoyance or injury), or cause any injury or damage to any occupants of the Premises or other tenants or occupants of the Building or their property; or (d) cause harmful air emissions or any unusual or other objectionable odors, noises or emissions to emanate from the Premises; (iv) in a manner which is inconsistent with the operation and/or maintenance of the Building as a first-class combination institutional, office and retail facility; (v) for any fermentation processes whatsoever; (vi) in a manner which shall increase such insurance rates on the Building or on property located therein over that applicable when ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇▇ first took occupancy of the Premises hereunder (provided that use of the Premises for the Permitted Uses generally shall not be deemed to result in any such increase); or (vii) for any use listed in Exhibit 6 attached hereto and made a part hereof. d(b) This clause 5With respect to the use and occupancy of the Premises and the Common Areas, Tenant will not: (i) shall continue place or maintain any garbage, trash, rubbish or other refuse (collectively, “Trash”), signage (except as may be permitted by Article 12 below) or other articles in any vestibule or entry of the Premises, on the footwalks or corridors adjacent thereto or elsewhere on the exterior of the Premises, nor obstruct any driveway, corridor, footwalk, parking area, mall or any other Common Areas; (ii) permit undue accumulations of or burn Trash within or without the Premises; (iii) permit the parking of vehicles so as to apply after termination interfere with the use of this Licence for any reasondriveway, corridor, footwalk, parking area, or other Common Areas; (iv) receive or ship articles of any kind outside of those areas reasonably designated by Landlord; (v) conduct or permit to be conducted any auction, going out of business sale, bankruptcy sale (unless directed by court order), or other similar type sale in or connected with the Premises; (vi) use the name of Landlord, Fee Owner, or any of Landlord’s affiliates or subsidiaries in any publicity, promotion, trailer, press release, advertising, printed, or display materials without Landlord’s prior written consent (which may be withheld in Landlord’s sole discretion); (vii) permit or keep any animals other than trained certified service animals in the Building; or (viii) except in connection with Tenant’s Fitout and/or Alterations (hereinafter defined) approved by Landlord, cause or permit any hole to be drilled or made in any part of the Building.

Prohibited Uses. a) The Licensee Tenant fmiher covenants and agrees that Tenant shall not use, or suffer or permit any person or persons to use, the Premises or any part thereof for any use reasonable efforts or purpose contrary to ensure that the Authorised Users are aware provisions of the prohibitions Rules and Regulations set forth in Exhibit D, attached hereto, or in violation of the laws of the United States of America, the State of California, or the ordinances, regulations or requirements of the local municipal or county governing body or other lawful authorities havingjurisdiction over the Project, including, without limitation, any such laws, ordinances, regulations or requirements relating to hazardous materials or substances, as those terms are defined by applicable laws now or hereafter in effect. Tenant shall not do or permit anything to be done in or about the Premises which will in any way damage the reputation of the Project or obstruct or interfere with the rights of other tenants or occupants of the Building, or injure or annoy them or use or allow the Premises to be used for any improper, unlawful or objectionable purpose, nor shall Tenant cause, maintain or permit any nuisance in, on or about the Premises. Tenant shall comply with, and Tenant's rights and obligations under the Lease and Tenant's use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee Premises shall be liable for subject and subordinate to, all recorded easements, covenants, conditions, and restrictions now or hereafter affecting the Project. Tenant shall not cause or permit any breach "Hazardous Substance," as that term is defined below, to be kept, maintained, used, stored, produced, generated or disposed of (into the sewage or waste disposal system or otherwise) on or in the Premises by Authorised Users Tenant or Tenant's agents, employees, contractors, invitees, assignees or sublessees, without first obtaining Landlord's written consent. Tenant shall immediately notify, and shall direct Tenant's agents, employees contractors, invitees, assignees and sublessees to immediately notify, Landlord of any of incident in, on or about the provisions of this LicencePremises, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) Building or the publisher’s copyright notices Project that would require the filing of a notice under any federal, state, local or other quasi-governmental law (whether under common law, statute or otherwise), ordinance, decree, code, ruling, award, rule, regulation or guidance document now or hereafter enacted or promulgated, as amended from time to time, in any way relating to or regulating any Hazardous Substance. As used herein, "Hazardous Substance" means any substance which is toxic, ignitable, reactive, or corrosive and which is regulated by any local government, the State of identification California, or the United States government. "Hazardous Substance" includes any and all disclaimers material or substances which are defined as they appear in the Licensed Materials; ii"hazardous waste," "extremely hazardous waste" or a "hazardous substance" pursuant to state, federal or local governmental law. "Hazardous Substance" also includes asbestos, polychlorobiphenyls (i.e., PCB's) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)petroleum. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee Tenant further covenants and agrees that Tenant shall use reasonable efforts not use, or suffer or permit any person or persons to ensure that use, the Authorised Users are aware of the prohibitions on the use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable Premises or any part thereof for any breach by Authorised Users of any of use or purpose contrary to the provisions of this Licencethe Rules and Regulations set forth in Exhibit D, including but attached hereto, or in violation of the laws of the United States of America, the State of California, or the ordinances, regulations or requirements of the local municipal or county governing body or other lawful authorities having jurisdiction over the Project, including, without limitation, any such laws, ordinances, regulations or requirements relating to hazardous materials or substances, as those terms are defined by applicable laws now or hereafter in effect. Tenant shall not limited do or permit anything to be done in or about the Premises which will in any way unreasonably obstruct or interfere with the rights of other tenants or occupants of the Building, or unreasonably injure or annoy them or use or allow the Premises to be used for any unlawful or reasonably objectionable purpose, nor shall Tenant cause, maintain or permit any nuisance (including, without limitation, foul or noxious odors in connection with the operation of the Cafeteria)(the parties hereby acknowledge and agree that any normal or reasonable food odors shall not be deemed to be foul or noxious) in, on or about the Premises. Notwithstanding the foregoing, (i) if occupants of the building reasonably complain of excessive cooking odors emanating from the Premises, or (ii) if a government entity notifies Tenant or Landlord of a violation of any federal, state or local law as a result of such cooking odors emanating from the Premises, the parties shall notify each other in writing (which writing shall include a copy of the government violation notice), Tenant shall, within fifteen (15) days after Tenant’s receipt of a government notice or Landlord’s written notice, deliver a written proposal to Landlord outlining a solution to the provisions odor problem for Landlord’s reasonable approval (and for the approval of any applicable governmental agency that has appeal rights). Tenant shall implement the Landlord approved solution within sixty (60) days after Tenant’s receipt of Landlord’s written notice of approval. Tenant’s failure to strictly comply with the requirements of this provision shall be a default under the Lease. Further, if Tenant fails to address the issue of odors emanating from the Premises within the time frames set out below. b) Authorised Users forth herein the Landlord may not: i) Remove or alter the authorelect in Landlord’s name(s) or the publisher’s copyright notices or other means of identification or any sole discretion, to develop and all disclaimers as they appear implement its own reasonable odor control plan in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet Premises and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission Tenant shall reimburse Landlord for the Authorised User to do so; vactual and reasonable out of pocket cost of developing and implementing the Landlord plan, which costs shall include a five percent (5%) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether supervision fee. Landlord shall in amended or unamended form) no event enter into any other work vi) make any Commercial Use of the Licensed Material (such easements, covenants, conditions and restrictions that reduce Tenant’s rights or increase Tenant’s obligations in whole or more than a di minimis amount as set forth in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)this Lease. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee Tenant and Tenant's agents shall use reasonable efforts not commit or --------------- suffer to ensure that be committed any waste upon the Authorised Users are aware Premises. Tenant and Tenant's agents shall not do or permit anything to be done in or about the Premises or Common Area which will in any way obstruct or interfere with the rights of any other tenants of the prohibitions Building, other authorized users of the Common Area, or occupants of neighboring property, or injure or annoy them. Tenant and Tenant's agents shall not use or allow the Premises to be used for any unlawful, immoral or hazardous purpose or any purpose not permitted by this Lease, nor shall Tenant or Tenant's agents cause, maintain, or permit any nuisance in, on or about the Premises. Tenant and Tenant's agents shall not do or permit anything to be done in or about the Premises nor bring or keep anything in the Premises which will in any way increase the rate of any insurance upon any portion of the Project or any of its contents, or cause a cancellation of any insurance policy covering any portion of the Project or any of its contents, nor shall Tenant or Tenant's agents keep, use or sell or permit to be kept, used or sold in or about the Premises any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance upon any portion of the Project or any of its contents is increased because of Tenant's particular use of the Licensed Materials set out Premises or that of Tenant's agents, Tenant shall pay, as Additional Rent, the full cost of such increase; provided, however this provision shall in this Licence and the Licensee shall use reasonable endeavours no event be deemed to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect constitute a waiver of their access Landlord's right to and use declare a default hereunder by reason of the Licensed Materialsact or conduct of Tenant causing such increase or of any other rights or remedies of Landlord in connection therewith. The Licensee Tenant and Tenant's agents shall not place any loads upon the floor, walls or ceiling of the Premises which would endanger the Building or the structural elements thereof or of the Premises, nor place any harmful liquids in the drainage system of the Building or Common Area. No waste materials or refuse shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited dumped upon or permitted to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of remain upon any part of the Licensed Materials Project except in enclosed trash containers designated for that purpose by Landlord. No materials, supplies, equipment, finished products (or semifinished products), raw materials, or other articles of any purpose other than that nature shall be stored upon, or be permitted by this Licence; iii) Prepare derivative works or downloadto remain on, mount or distribute any part portion of the Licensed Material on any electronic system or network, including without limitation Project outside the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)Premises. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee Tenant further covenants and agrees that Tenant shall not use, or suffer or permit any person or persons to use, the Premises or any part thereof for any use reasonable efforts or purpose in violation of Applicable Laws. Landlord shall have the right to ensure that the Authorised Users are aware of the prohibitions on impose Rules and Regulations regarding the use of the Licensed Materials set out Project, as reasonably deemed necessary by Landlord with respect to the orderly operation of the Project, and Tenant shall comply with such Rules and Regulations. Nothing contained in this Licence Lease shall be construed to impose upon Landlord any duty or obligation to enforce the rules and regulations or the Licensee terms, covenants or conditions in any other lease as against any other tenant and Landlord shall use reasonable endeavours not be liable to ensure that Tenant for violation of the same by any other tenant, its Authorised Users servants, employees, agents, contractors, visitors, invitees or licensees. Tenant shall not do not breach or permit anything to be done in or about the prohibitions set out Premises which will in this Licence in respect any way (a) damage the reputation of their access to and the Project (provided, however, the use of the Licensed Materials. The Licensee Premises for the Permitted Use (including vivarium use) shall not be liable for any breach by Authorised Users deemed in and of itself to damage the reputation of the Project), (b) impair, interfere with or otherwise diminish the quality of any of the provisions Building services or the proper and economic heating, cleaning, ventilating, air conditioning or other servicing of this Licencethe Building or Premises, including but or the use of any of the Common Areas, (c) obstruct or interfere with the rights of other tenants or occupants of the Building, or injure them, (d) use or allow the Premises to be used for any improper, unlawful or objectionable purpose, (e) cause laboratory odors or noises (that are not limited typical of First Class Life Sciences Projects in which vivariums are operated) or harmful air emissions to emanate from the provisions set out below. bPremises; (f) Authorised Users may not: increase such insurance rates on the Building or on property located therein over that applicable when Tenant first took occupancy of the Premises hereunder, or (g) cause, maintain or permit any legal nuisance in, on or about the Premises. Furthermore, Tenant shall not (i) Remove place or alter the author’s name(s) or the publisher’s copyright notices maintain any garbage, trash, rubbish or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or downloadrefuse (collectively, mount or distribute any part of the Licensed Material on any electronic system or network“Trash”), including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials signage (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). cSection 23 below) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out other articles in any vestibule or entry of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination Premises, on the footwalks or corridors adjacent thereto or elsewhere on the exterior of this Licence for the Premises, nor obstruct any reason.driveway, corridor, footwalk, parking area, mall or any other Common

Prohibited Uses. a) The Licensee Tenant and Tenant's agents shall use reasonable efforts not commit or suffer to ensure that be committed any waste upon the Authorised Users are aware Premises. Tenant and Tenant's agents shall not do or permit anything to be done in or about the Premises or Common Area which will in any way obstruct or interfere with the rights of any authorized users of the prohibitions Common Area, or injure or annoy them. Tenant shall not conduct or permit any auction or sale open to the public to be held or conducted on or about the Premises or Common Area. Tenant and Tenant's agents shall not use or allow the Premises to be used for any unlawful, immoral or hazardous purpose or any purpose not permitted by this Lease, nor shall Tenant or Tenant's agents cause, maintain, or permit any nuisance in, on or about the Premises. Tenant and Tenant's agents shall not do or permit anything to be done in or about the Premises or Common Area nor bring or keep anything in the Premises or Common Area which will in any way increase the rate of any insurance upon the Premises or Common Area or any part thereof or any of its contents, or cause a cancellation of any insurance policy covering the Premises or Common Area or any part thereof or any of its contents, nor shall Tenant or Tenant's agents keep, use or sell or permit to be kept, used or sold in or about the Premises any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance upon the Premises or Common Area or any part thereof or any of its contents is increased because of the acts or omissions of Tenant or Tenant's agents, Tenant shall pay, as Additional Rent, the full cost of such increase to the extent attributable solely to Tenant's or its agents' acts or omissions; provided however this provision shall in no event be deemed to constitute a waiver of Landlord's rights or remedies of Landlord in connection with such increase. Tenant and Tenant's agents shall not place any loads upon the floor, walls or ceiling of the Premises which would endanger the Premises or the structural elements thereof, nor place any harmful liquids in the drainage system of the Premises. No waste materials or refuse shall be dumped upon or permitted to remain upon any part of the Premises or Common Area except in enclosed trash containers. No materials, supplies, equipment, finished products (or semi-finished products), raw materials, or other articles of any nature shall be stored upon, or be permitted to remain on, any portion of the Common Area. Tenant shall not allow any activity which in the reasonable opinion of Landlord is detrimental to the operation of the Common Area or to tenants of Landlord in other buildings located on the use of Common Area or upon real property owned by Landlord adjacent to the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users of any of the provisions of this LicenceCommon Area, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices any picketing, work stoppage, or other means concerted activity. Landlord shall have the right to require Tenant, at Tenant's own expense and within a reasonable period of identification time, to use Tenant's commercially reasonably efforts to terminate or control any and all disclaimers as they appear in such picketing, work stoppage or other concerted activity to the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of extent necessary to eliminate any part interference with the operation of the Licensed Materials for any purpose other than that permitted Common Area or such tenants. Failure by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User Tenant to use its commercially reasonable efforts to do so; v) Alter, edit, abridge so shall be a Default by Tenant. Nothing contained in this paragraph shall be construed as placing Landlord in an employer-employee relationship with any of Tenant's employees or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into with any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise employees who may be permitted under Appendix B (including by way of inter-library lending)involved in such activity. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee Sublessee shall use reasonable efforts to ensure that the Authorised Users are aware of the prohibitions on not use, or suffer or permit the use of of, or suffer or permit anything to be done in the Licensed Materials set out in this Licence and Sublease Premises or the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for Building or any breach by Authorised Users of part thereof (i) which would violate any of the covenants, agreements, terms, provisions and conditions of this Sublease, (ii) for any unlawful purposes or in any unlawful manner, or (iii) which, in the reasonable judgment of Sublessor or Landlord shall in any way (a) impair or tend to impair the appearance or reputation of the Building, (b) impair or interfere with or tend to impair or interfere with any of the Building services or the proper and economic heating, cleaning, air conditioning or other servicing of the Building, or (c) occasion discomfort, inconvenience or annoyance to any of the other tenants or occupants of the Building, whether through the transmission of noise or odors or otherwise. Without limiting the generality of the foregoing, no food (except in connection with customary office vending machines, coffee service facilities and lunch room facilities set forth on the Complete Plans or other plans approved by Sublessor, provided such machines and facilities are used for and by occupants of the Sublease Premises only and their guests and further provided Sublessee pays any resulting increased costs pursuant to Section 13.8 and the other applicable provisions of this Licence, including but not limited Sublease) shall be prepared or served for public or commercial consumption on or about the Sublease Premises; no intoxicating liquors or alcoholic beverages shall be sold or otherwise served to the provisions set out below. bgeneral public on or about the Sublease Premises; no lottery tickets (even where the sale of such tickets is not illegal) Authorised Users may not: ishall be sold and no gambling, betting or wagering shall otherwise be permitted on or about the Sublease Premises; no combustible materials (except as disclosed to and approved by Sublessor) Remove shall be stored or alter warehoused; no loitering shall be permitted on or about the author’s name(s) Sublease Premises; and no loading or the publisher’s copyright notices unloading of supplies or other means material to or from the Sublease Premises shall be permitted on the Lot except during such hours as the Building is customarily open for business. The Sublease Premises shall be maintained by Sublessee in a sanitary condition, kept free from odors and kept free from rodents and laboratory animals of identification or any kind and vermin. Sublessee shall be responsible for the proper handling and disposal of all disclaimers as they appear its trash, rubbish and other wastes, and for compliance with all local, state and federal laws applicable to the storage and disposal of any such wastes. Sublessee shall also provide cleaning services to the Sublease Premises according to cleaning standards generally prevailing in first class buildings in the Licensed Materials; ii) Systematically make print City of Boston and in accordance with any cleaning specifications or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted rules and regulations promulgated from time to time by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet Landlord and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)Sublessor. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee TENANT shall not use reasonable efforts to ensure that the Authorised Users are aware of the prohibitions on the use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable said Premises for any breach by Authorised Users of any of the provisions of this Licence, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose use other than that permitted by this Licence; iii) Prepare derivative works or downloadwhich is specified in the Lease, mount or distribute and shall not permit them to be used, for any part other purpose, without first obtaining the written consent of LANDLORD. TENANT shall promptly and continuously comply with all laws, orders, and regulations of the Licensed Material on any electronic system or networkState, including without limitation County and City, affecting the Internet use, occupation, safety and cleanliness of the Premises and the World Wide Webequipment of TENANT . TENANT may not display or sell items or allow carts, other than by the Licensee’s Secure Network approved in advance by The Company of Biologistsportable signs, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials devices or any other objects to be stored or to remain outside the exterior walls and permanent doorways of the Premises. TENANT further agrees not to install any exterior lighting, amplifiers or similar devices or use in or about the Premises any advertising medium which may be heard or seen outside the Premises, such as flashing lights, searchlights, loudspeakers, phonographs or radio broadcasts. TENANT shall not do or permit anything to be done in or about the Premises nor bring or keep anything therein which will in any way increase the existing rate or affect any fire or other insurance upon the Premises or the Building or any of its contents, nor shall TENANT sell or permit any articles to be kept, used or sold in or about the Premises, which may be prohibited by a standard form policy of fire insurance. If LANDLORD’S insurance premium is increased as a result of TENANT ‘S business operation, TENANT agrees to pay said increase. In the event Premises represent a section of a larger Building, TENANT shall not do or permit anything to be done in or about the Premises which will in any way obstruct or interfere with the rights of other tenants or occupants of the Building of which the Premises may be a part of them or injure or annoy them, or use or allow the Premises to be used for any purpose whatsoever unlawful or incorporate objectionable purpose, nor shall TENANT cause, maintain or permit any part nuisance in, on, or about the Premises. TENANT shall not commit or allow to be committed any waste in or upon Premises. TENANT shall keep the Premises in a clean and wholesome condition, free of any Licensed Materials (whether in amended objectionable noises, odors or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)nuisances. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee Tenant and Tenant’s agents shall use reasonable efforts not commit or suffer to ensure that be committed any waste upon the Authorised Users are aware Premises. Tenant and Tenant’s agents shall not do or permit anything to be done in or about the Premises, Building, Project or Common Area which will in any way obstruct or interfere with the rights of any other tenants of the prohibitions Project, other authorized users of the Common Area, or occupants of neighboring property, or injure or annoy them. Tenant shall not conduct or permit any auction or sale open to the public to be held or conducted on or about the Premises, Building, Project or Common Area. Tenant and Tenant’s agents shall not use or allow the Premises to be used for any unlawful, immoral or hazardous purpose or any purpose not permitted by this Lease, nor shall Tenant or Tenant’s agents cause, maintain, or permit any nuisance in, on or about the Premises, Building, Project or Common Area. Tenant shall not overload existing electrical systems or other mechanical equipment servicing the Building, impair the efficient operation of the sprinkler system or the heating, ventilation or air conditioning equipment within or servicing the Building or damage, overload or corrode the sanitary sewer system. Tenant and Tenant’s agents shall not do or permit anything to be done in or about the Premises nor bring or keep anything in the Premises which will in any way increase the rate of any insurance upon any portion of the Project or any of its contents, or cause a cancellation of any insurance policy covering any portion of the Project or any of its contents, nor shall Tenant or Tenant’s agents keep, use or sell or permit to be kept, used or sold in or about the Premises any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance upon any portion of the Project or any of its contents is increased because of Tenant’s particular use of the Licensed Materials set out Premises or that of Tenant’s agents, Tenant shall pay, as Additional Rent, the full cost of such increase; provided, however this provision shall in this Licence and the Licensee shall use reasonable endeavours no event be deemed to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect constitute a waiver of their access Landlord’s right to and use declare a default hereunder by reason of the Licensed Materialsact or conduct of Tenant or Tenant’s agents causing such increase or of any other rights or remedies of Landlord in connection therewith. The Licensee Tenant and Tenant’s agents shall not place any loads upon the floor, walls or ceiling of the Premises which would endanger the Building or the structural elements thereof or of the Premises, nor place any harmful liquids in the drainage system of the Building or Common Area. No waste materials or refuse shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited dumped upon or permitted to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of remain upon any part of the Licensed Materials Project except in enclosed trash containers designated for that purpose by Landlord. No materials, supplies, equipment, finished products (or semi-finished products), raw materials, or other articles of any purpose other than that nature shall be stored upon, or be permitted by this Licence; iii) Prepare derivative works or downloadto remain on, mount or distribute any part portion of the Licensed Material on any electronic system or network, including without limitation Project outside the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)Premises. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee Tenant further covenants and agrees that Tenant shall not use, or suffer or permit any person or persons to use, the Premises or any part thereof for any use reasonable efforts to ensure that the Authorised Users are aware or purpose in violation of the prohibitions on laws of the United States of America, the State of California, or the ordinances, regulations or requirements of the local municipal or county governing body or other lawful authorities having jurisdiction over the Project) including, without limitation, any such laws, ordinances, regulations or requirements relating to hazardous materials or substances, as those terms are defined by Applicable Laws now or hereafter in effect, or any Underlying Documents. Landlord shall have the right to impose reasonable and customary rules and regulations based upon the nature of the Project as either a single-tenant or a multi-tenant First Class Life Sciences Project (which rules and regulations shall be modified by Landlord in accordance with Tenant’s reasonable requests, from time to time, taking into account whether or not Tenant and its Permitted Transferees are the sole occupants of all occupied space in the Project) regarding the use of the Licensed Materials set out Project, as reasonably deemed necessary by Landlord with respect to the orderly operation of the Project as either a single-tenant or multi-tenant First Class Life Sciences Project, including, but not limited to, reasonable rules and regulations for the safe and sanitary operation of any fitness/wellness center or cafeteria operated by Tenant, and for the reasonable mitigation of noise, odors and other effects of such operations on other occupants of the Project, and provided that such rules and regulations are consistent with rules and regulations then being enforced by landlords of Comparable Buildings, with respect to tenants leasing a similar proportion of First Class Life Sciences Projects as Tenant is then leasing pursuant to this Lease, Tenant shall comply with such rules and regulations. Tenant shall not do or permit anything to be done in this Licence or about the Premises which will in any way damage the reputation of the Project or obstruct or interfere with the rights of other tenants or occupants of the Buildings, or injure or annoy them or use or allow the Premises to be used for any improper, unlawful or objectionable purpose, nor shall Tenant cause, maintain or permit any nuisance in, on or about the Premises. Tenant shall comply with, and Tenant's rights and obligations under the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to Lease and Tenant's use of the Licensed Materials. The Licensee Premises shall be liable for any breach by Authorised Users of any of subject and subordinate to, all recorded easements, covenants, conditions, and restrictions now or hereafter affecting the provisions of this Licence, including but not limited to the provisions set out belowProject. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee Tenant shall not commit or permit any Tenant Related Parties to commit any waste upon the Premises or Common Area. Tenant and Tenant Related Parties shall not do or permit anything to be done in the Premises or do or permit anything to be done by any of them in other parts of the Building, Project or Common Area which will obstruct or interfere with the rights of any other tenants of the Project, other authorized users of the Common Area, or occupants of neighboring property, or injure or unreasonably annoy them. Tenant shall not conduct or permit any auction or sale open to the public to be held or conducted on or about the Premises, Building, Project or Common Area. Neither Tenant nor any Tenant Related Parties shall use reasonable efforts or knowingly allow the Premises to ensure that be used for any hazardous purpose, nor shall Tenant or any Tenant Related Parties cause, maintain, or permit any nuisance in, on or about the Authorised Users are aware Premises, Building, Project or Common Area. Tenant shall not overload existing electrical systems or other mechanical equipment servicing the Building, impair the efficient operation of the prohibitions on sprinkler system or the heating, ventilation or air conditioning equipment within or servicing the Building or Premises or damage (ordinary wear and tear excepted), overload or corrode or misuse the sanitary sewer system. Tenant and Tenant Related Parties shall not do or knowingly permit anything to be done in or about the Premises nor bring or keep anything in the Premises which will in any way increase the rate of any insurance upon any portion of the Project or any of its contents, or cause a cancellation of any insurance policy covering any portion of the Project or any of its contents, nor shall Tenant or any Tenant Related Parties keep, use or sell or permit to be kept, used or sold in or about the Premises any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance upon any portion of the Project or any of its contents is increased because of Tenant’s or any Tenant Related Party’s particular use of the Licensed Materials set out Premises, Tenant shall pay, as Additional Rent, the full cost of such increase; provided, however this provision shall in this Licence and the Licensee shall use reasonable endeavours no event be deemed to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect constitute a waiver of their access Landlord’s right to and use declare a default hereunder by reason of the Licensed Materialsact or conduct of Tenant or any Tenant Related Parties causing such increase or of any other rights or remedies of Landlord in connection therewith. The Licensee Tenant and Tenant Related Parties shall not place any loads upon the floor, walls or ceiling of the Premises which would endanger the Building or the structural elements thereof or of the Premises, nor place any harmful liquids in the drainage system of the Building or Common Area. No waste materials or refuse shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited dumped upon or permitted to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of remain upon any part of the Licensed Materials Project except in enclosed trash containers designated for that purpose by Landlord. No materials, supplies, equipment, finished products (or semi-finished products), raw materials, or other articles of any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part nature shall be stored outside of the Licensed Material on any electronic system Premises, or network, including without limitation be permitted to remain outside of the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of BiologistsPremises, except where expressly permitted under this Licence; iv) Sell for temporary loading and unloading. Tenant shall not tint or resell frost, or permit any Tenant Related Parties or their respective contractors or representatives to tint or frost, the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use windows of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use first floor of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)Building. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee Tenant further covenants and agrees that Tenant shall not use, or suffer or permit any person or persons to use, the Premises or any part thereof for any use reasonable efforts to ensure that the Authorised Users are aware or purpose in violation of the prohibitions on laws of the United States of America, the State of California, or the ordinances, regulations or requirements of the local municipal or county governing body or other lawful authorities having jurisdiction over the Project) including, without limitation, DOCPROPERTY "Document number" 4884-2045-4146. DOCPROPERTY "Document version" 4 DOCPROPERTY "Client" 186772. DOCPROPERTY "Matter" 00003/ SAVEDATE \@ M-d-yy 3-21-23/ DOCPROPERTY "User Init" mem/ DOCPROPERTY "Typist Init" ejs DOCPROPERTY "Footer Notes" HEALTHPEAK[Towers at Sierra Point][Tempest Therapeutics, Inc.] any such laws, ordinances, regulations or requirements relating to hazardous materials or substances, as those terms are defined by Applicable Laws now or hereafter in effect, or any Underlying Documents. Landlord shall have the right to impose reasonable and customary rule and regulations regarding the use of the Licensed Materials set out Project, as reasonably deemed necessary by Landlord with respect to the orderly operation of the Project, and Tenant shall comply with such reasonable rules and regulations, which shall not be enforced in this Licence a manner intended to discriminate against Tenant. In the event of a conflict between the rules and regulations and the Licensee terms of this Lease, the terms of this Lease shall control. Tenant shall not use reasonable endeavours or allow the Premises to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable used for any breach by Authorised Users of any of the provisions of this Licenceimproper, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyoneunlawful, or transmit objectionable purpose or do or permit anything to be done in or about the Premises which will cause, maintain or permit any part of nuisance in, on or about the Licensed Material (other than Metadata) by any means to anyonePremises. Tenant shall comply with, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@'s rights and obligations under the Lease and ▇▇▇▇▇▇▇▇▇▇'s use of the Premises shall be subject and subordinate to, all recorded easements, covenants, conditions, and restrictions now or hereafter affecting the Project.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. Tenant shall comply with all of the following: (a) The Licensee Tenant shall use reasonable efforts not do or permit anything to ensure that be done in or about the Authorised Users are aware Premises nor bring nor keep anything therein which could cause a cancellation of any insurance policy covering the Premises, the Building, any part thereof or any of its contents. (b) Tenant shall not do or permit anything to be done in or about the Premises which would in any way obstruct or interfere with the rights of other tenants or occupants of the prohibitions Building or injure or annoy them. (c) Tenant shall not use or allow the Premises to be used for my unlawful purpose or in any manner that constitutes a public nuisance. (d) Tenant shall not cause, maintain, suffer or permit any nuisance in, on or about the use Premises. (e) Tenant shall not permit noise or odors in the Premises which are objected to by Landlord or by any tenant or occupant of the Licensed Materials set Building, and, upon written notice from Landlord, Tenant shall immediately cease and desist from causing such noise or odor. (f) Tenant shall not commit or allow to be committed any waste in or upon the Premises. (g) Tenant shall not use or permit the Premises or any portion thereof to be used as living quarters, sleeping quarters or for lodging purposes or for any unlawful purposes. (h) Tenant shall not conduct any auctions, liquidation, going out in this Licence of business, fire or bankruptcy sales on or about the Premises. (i) Tenant agrees that all receiving and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect delivery of their access to goods and use merchandise and all removal of the Licensed Materials. The Licensee merchandise, supplies, equipment, trash and garbage shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including made only by way of inter-library lending)the south rear entrance of the Building. c(j) The Licensee must seek and obtain The Company of Biologists’ permission prior Tenant shall not place, or permit to carrying out be placed, any merchandise or attempting to carry out any other obstruction on the sidewalks immediately adjoining the Premises. (k) Tenant shall not go upon the roof of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇Building or permit anyone else to do so without Landlord's prior approval except for maintenance of equipment. d(1) This clause 5) Tenant shall continue to apply after termination of this Licence not obstruct the Common Area and/or store anything in the Common Area or outside the Building except for any reasonspace expressly designated by Landlord for storage.

Prohibited Uses. a) The Licensee Tenant and Tenant’s agents shall use reasonable efforts not commit or suffer to ensure that be committed any waste upon the Authorised Users are aware Premises. Tenant and Tenant’s agents shall not do or permit anything to be done in or about the Premises or Common Area which will in any way obstruct or interfere with the rights of any authorized users of the prohibitions Common Area or occupants of neighboring property, or injure or annoy them. Tenant shall not conduct or permit any auction or sale open to the public to be held or conducted on or about the Premises or Common Area. Tenant and Tenant’s agents shall not use or allow the Premises to be used for any unlawful, immoral or hazardous purpose or any purpose not permitted by this Lease, nor shall Tenant or Tenant’s agents cause, maintain, or permit any nuisance in, on or about the Premises. Tenant and Tenant’s agents shall not do or permit anything to be done in or about the Premises or Common Area nor bring or keep anything in the Premises or Common Area which will in any way increase the rate of any insurance upon the Premises or Common Area or any part thereof or any of its contents, or cause a cancellation of any insurance policy covering the Premises or Common Area or any part thereof or any of its contents, nor shall Tenant or Tenant’s agents keep, use or sell or permit to be kept, used or sold in or about the Premises any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance upon the Premises or Common Area or any part thereof or any of its contents is increased because of Tenant’s particular use of the Licensed Materials set out Premises or that of Tenant’s agents, Tenant shall pay, as Additional Rent, the full cost of such increase; provided however this provision shall in this Licence and the Licensee shall use reasonable endeavours no event be deemed to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect constitute a waiver of their access Landlord’s right to and use declare a default hereunder by reason of the Licensed Materialsact or conduct of Tenant or Tenant’s agents causing such increase or of any other rights or remedies of Landlord in connection therewith. The Licensee Tenant and Tenant’s agents shall not place any loads upon the floor, walls or ceiling of the Premises which would endanger the Premises or the structural elements thereof, nor place any harmful liquids in the drainage system of the Premises. No waste materials or refuse shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited dumped upon or permitted to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of remain upon any part of the Licensed Materials Premises or Common Area except in enclosed trash containers designated for that purpose by Landlord. No materials, supplies, equipment, finished products (or semi-finished products), raw materials, or other articles of any purpose other than that nature shall be stored upon, or be permitted by this Licence; iii) Prepare derivative works or downloadto remain on, mount or distribute any part portion of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)Common Area. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. (a) The Licensee Notwithstanding any other provision of this Lease, Tenant shall not use reasonable efforts to ensure that the Authorised Users are aware Premises or the Building, or any part thereof, or suffer or permit the use or occupancy of the prohibitions on Premises or the Building or any part thereof by any of the Tenant Parties (i) in a manner which would violate any of the covenants, agreements, terms, provisions and conditions of this Lease or otherwise applicable to or binding upon the Premises; (ii) for any unlawful purposes or in any unlawful manner; (iii) which, in the reasonable judgment of Landlord (taking into account the use of the Licensed Materials set out in this Licence Building as a combination laboratory, research and development and office building and the Licensee Permitted Uses) shall use reasonable endeavours to ensure that its Authorised Users do not breach (a) impair the prohibitions set out in this Licence in respect of their access to and use appearance or reputation of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users Building; (b) impair, interfere with or otherwise diminish the quality of any of the provisions Building services or the proper and economic heating, cleaning, ventilating, air conditioning or other servicing of this Licencethe Building or Premises, including but or the use or occupancy of any of the Common Areas; (c) occasion discomfort, inconvenience or annoyance in any material respect (and Tenant shall not limited install or use any electrical or other equipment of any kind which, in the reasonable judgment of Landlord, will cause any such impairment, interference, discomfort, inconvenience, annoyance or injury), or cause any injury or damage to any occupants of the Premises or other tenants or occupants of the Building or their property; or (d) cause air emissions not permitted by Legal Requirements, laboratory odors or noises or any unusual or other objectionable odors, noises or emissions to emanate from the Premises; (iv) in a manner which is inconsistent with the operation and/or maintenance of the Building as a first-class combination office, research, development and laboratory facility; (v) for any fermentation processes whatsoever; or (vi) in a manner which shall increase such insurance premiums on the Building or on property located therein over that applicable when Tenant first took occupancy of the Premises hereunder, unless Tenant pays for such increase. (b) With respect to the provisions set out below. b) Authorised Users may use and occupancy of the Premises and the Common Areas, Tenant will not: : (i) Remove place or alter maintain any signage (except as set forth in Section 12.2 below), trash, refuse or other articles in any vestibule or entry of the authorPremises, on the footwalks or corridors adjacent thereto or elsewhere on the exterior of the Premises, nor obstruct any driveway, corridor, footwalk, parking area, mall or any other Common Areas; (ii) permit undue accumulations of or burn garbage, trash, rubbish or other refuse within or without the Premises; (iii) permit the parking of vehicles so as to interfere with the use of any driveway, corridor, footwalk, parking area, or other Common Areas; (iv) receive or ship articles of any kind outside of those areas reasonably designated by Landlord; (v) conduct or permit to be conducted any auction, going out of business sale, bankruptcy sale (unless directed by court order), or other similar type sale in or connected with the Premises; (vi) use the name of Landlord, or any of Landlord’s name(saffiliates in any publicity, promotion, trailer, press release, advertising, printed, or display materials without Landlord’s prior written consent; or (vii) except in connection with Alterations (hereinafter defined) approved by Landlord or the publisherTenant’s copyright notices Work, cause or other means of identification permit any hole to be drilled or any and all disclaimers as they appear made in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)Building. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee Tenant and Tenant's agents shall use reasonable efforts not commit or --------------- suffer to ensure that be committed any waste upon the Authorised Users are aware Premises. Tenant and Tenant's agents shall not do or permit anything to be done in or about the Premises or Common Area which will in any way obstruct or unreasonably interfere with the rights of any other tenants of the prohibitions Building, other authorized users of the Common Area, or occupants of neighboring property, or injure them. Tenant shall not conduct or permit any auction or sale open to the public to be held or conducted on or about the Premises or Common Area. Tenant and Tenant's agents shall not use or allow the Premises to be used for any unlawful, immoral or hazardous purpose or any purpose not permitted by this Lease, nor shall Tenant or Tenant's agents cause, maintain, or permit any nuisance in, on or about the Premises. Tenant and Tenant's agents shall not do or permit anything to be done in or about the Premises nor bring or keep anything in the Premises which will in any way increase the rate of any insurance upon any portion of the Project or any of its contents, or cause a cancellation of any insurance policy covering any portion of the Project or any of its contents, nor shall Tenant or Tenant's agents keep, use or sell or permit to be kept, used or sold in or about the Premises any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance upon any portion of the Project or any of its contents is increased because of Tenant's particular use of the Licensed Materials set out Premises or that of Tenant's agents, Tenant shall pay, as Additional Rent, the full cost of such increase; provided, however this provision shall in this Licence and the Licensee shall use reasonable endeavours no event be deemed to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect constitute a waiver of their access Landlord's right to and use declare a default hereunder by reason of the Licensed Materialsact or conduct of Tenant or Tenant's agents causing such increase or of any other rights or remedies of Landlord in connection therewith. The Licensee Tenant and Tenant's agents shall not place any loads upon the floor, walls or ceiling of the Premises which would endanger the Building or the structural elements thereof or of the Premises, nor place any harmful liquids in the drainage system of the Building or Common Area. No waste materials or refuse shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited dumped upon or permitted to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of remain upon any part of the Licensed Materials Project except in enclosed trash containers designated for that purpose by Landlord. No materials, supplies, equipment, finished products (or semi-finished products), raw materials, or other articles of any purpose other than that nature shall be stored upon, or be permitted by this Licence; iii) Prepare derivative works or downloadto remain on, mount or distribute any part portion of the Licensed Material on any electronic system or network, including without limitation Project outside the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)Premises. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee Tenant and Tenant’s agents shall use reasonable efforts not commit or suffer to ensure that be committed any waste upon the Authorised Users are aware Premises. Tenant and Tenant’s agents shall not do or permit anything to be done in or about the Premises or Common Area which will in any way unreasonably obstruct or unreasonably interfere with the rights of any other tenants of the prohibitions Building, other authorized users of the Common Area, or occupants of neighboring property, or injure or annoy them. Tenant shall not conduct or permit any auction or sale open to the public to be held or conducted on or about the Premises or Common Area. Tenant and Tenant’s agents shall not use or allow the Premises to be used for any unlawful or hazardous purpose or any purpose not permitted by this Lease, nor shall Tenant or Tenant’s agents cause, maintain, or permit any nuisance in, on or about the Premises. Tenant and Tenant’s agents shall not do or permit anything to be done in or about the Premises nor bring or keep anything in the Premises which will in any way increase the rate of any insurance upon any portion of the Project or any of its contents, or cause a cancellation of any insurance policy covering any portion of the Project or any of its contents, nor shall Tenant or Tenant’s agents keep, use or sell or permit to be kept, used or sold in or about the Premises any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance upon any portion of the Project or any of its contents is increased because of Tenant’s particular use of the Licensed Materials set out Premises or that of Tenant’s agents, Tenant shall pay, as Additional Rent, the full cost of such increase; provided, however this provision shall in this Licence and the Licensee shall use reasonable endeavours no event be deemed to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect constitute a waiver of their access Landlord’s right to and use declare a default hereunder by reason of the Licensed Materialsact or conduct of Tenant or Tenant’s agents causing such increase or of any other rights or remedies of Landlord in connection therewith. The Licensee Tenant and Tenant’s agents shall not place any loads upon the floor, walls or ceiling of the Premises which would endanger the Building or the structural elements thereof or of the Premises, nor place any harmful liquids in the drainage system of the Building or Common Area. No waste materials or refuse shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited dumped upon or permitted to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of remain upon any part of the Licensed Materials Project except in enclosed trash containers designated for that purpose by Landlord. No materials, supplies, equipment, finished products (or semi-finished products), raw materials, or other articles of any purpose other than that nature shall be stored upon, or be permitted by this Licence; iii) Prepare derivative works or downloadto remain on, mount or distribute any part portion of the Licensed Material on any electronic system or network, including without limitation Project outside the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)Premises. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee LESSEE shall not use reasonable efforts to ensure that the Authorised Users are aware of the prohibitions on the use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable said Premises for any breach by Authorised Users of any of the provisions of this Licence, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose use other than that permitted by which is specified in this Licence; iii) Prepare derivative works or downloadLease, mount or distribute and shall not permit them to be used, for any part other purposes, without first obtaining the written consent of LESSOR, which consent shall not be unreasonably withheld. LESSEE shall promptly and continuously comply with all laws, orders, and regulations of the Licensed Material on any electronic system or networkState, including without limitation County, and City affecting the Internet use, occupation, safety, and cleanliness of the said Premises and the World Wide Webequipment of LESSEE. LESSEE may not display or sell items or allow carts, other than by the Licensee’s Secure Network approved in advance by The Company of Biologistsportable signs, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials devices or any other objects to be stored or to remain outside the defined exterior walls and permanent doorways of the Premises. LESSEE further agrees not to install any exterior lighting, amplifiers or similar devices or use in or about the Premises, nor any advertising medium which may be heard or seen outside the Premises, such as flashing lights, searchlights, loudspeakers, phonographs, or radio broadcasts. LESSEE shall not do or permit anything to be done in or about the Premises nor bring in or keep anything therein which will in any way increase the existing rate or affect any fire or other insurance upon the Premises or any building of which the Premises may be a part or any of them its contents, nor shall LESSEE sell or permit any articles to be kept, used or sold in or about the Premises, which may be prohibited by a standard form policy of fire insurance. If LESSOR'S insurance premium is increased as a result of LESSEE'S business operation, LESSEE agrees to pay said increase. In the event the Premises represent a section of a larger building, LESSEE shall not do or permit anything to be done in or about the Premises which will in any way obstruct or interfere with the rights of other tenants or occupants of the building of which the Premises may be a part, or injure or annoy them, or use or allow the Premises to be used for any purpose whatsoever unlawful or incorporate objectionable purpose, nor shall LESSEE cause, maintain or permit any part nuisance in, or on, or about the Premises. LESSEE shall not commit or allow to be committed any waste in or upon the Premises. LESSEE shall keep the Premises in a clean and wholesome condition, free of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyonereasonably objectionable noises, odors, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)nuisances beyond its contemplated uses set forth herein. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee Tenant and Tenant’s agents shall use reasonable efforts not commit or suffer to ensure that be committed any waste upon the Authorised Users are aware Premises. Tenant and Tenant’s agents shall not do or permit anything to be done in or about the Premises or Common Area which will in any way obstruct or interfere with the rights of any authorized users of the prohibitions Common Area or occupants of neighboring property, or injure or unreasonably annoy them. Tenant shall not conduct or permit any auction or sale open to the public to be held or conducted on or about the Premises or Common Area. Tenant and Tenant’s agents shall not use or allow the Premises to be used for any unlawful, immoral or hazardous purpose or any purpose not permitted by this Lease, nor shall Tenant or Tenant’s agents cause, maintain, or permit any nuisance in, on or about the Premises. Tenant and Tenant’s agents shall not do or permit anything to be done in or about the Premises or Common Area nor bring or keep anything in the Premises or Common Area which will in any way increase the rate of any insurance upon the Premises or Common Area or any part thereof or any of its contents, or cause a cancellation of any insurance policy covering the Premises or Common Area or any part thereof or any of its contents, nor shall Tenant or Tenant’s agents keep, use or sell or permit to be kept, used or sold in or about the Premises any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance upon the Premises or Common Area or any part thereof or any of its contents is increased because of the Licensed Materials set out acts or omissions of Tenant or Tenant’s agents, Tenant shall pay, as Additional Rent, the full cost of such increase; provided however this provision shall in this Licence no event be deemed to constitute a waiver of Landlord’s right to declare a default hereunder by reason of such increase or of any other rights or remedies of Landlord in connection with such increase. Tenant and Tenant’s agents shall not place any loads upon the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use floor, walls or ceiling of the Licensed MaterialsPremises which would endanger the Premises or the structural elements thereof, nor place any harmful liquids in the drainage system of the Premises. The Licensee No waste materials or refuse shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited dumped upon or permitted to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of remain upon any part of the Licensed Materials for Premises or Common Area except in enclosed trash containers. No materials, supplies, equipment, finished products (or semifinished products), raw materials, or other articles of any purpose other than that nature shall be stored upon, or be permitted by this Licence; iii) Prepare derivative works or downloadto remain on, mount or distribute any part portion of the Licensed Material on Common Area. Landlord shall have the right to require Tenant, at Tenant’s own expense and within a reasonable period of time, to use Tenant’s commercially reasonable efforts to terminate or control any electronic system picketing, work stoppage or network, including without limitation other concerted activity related to Tenant’s business operations to the Internet and extent necessary to eliminate any interference with the World Wide Web, operation of the Common Area or other than by tenants who use the LicenseeCommon Area. Nothing contained in this paragraph shall be construed as placing Landlord in an employer-employee relationship with any of Tenant’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell employees or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into with any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise employees who may be permitted under Appendix B (including by way of inter-library lending)involved in such activity. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. (a) The Licensee shall use reasonable efforts to ensure Tenant agrees that the Authorised Users are aware neither Tenant nor any subtenant, assignee or occupant of the prohibitions on Demised Premises shall at any time during the term of this lease occupy or use the Demised Premises or permit the same to be used or occupied in any manner except as provided in Section 9.01. The following non-exclusive list of uses shall not be deemed to be "executive, administrative, accounting and general office purposes", and Tenant shall not use, or permit the use of, the Demised Premises or any part thereof, for: (i) the conduct of a public auction of any kind, or of any gaming or gambling activities, or for any political or club activities, whether public or private; (ii) the conduct of a school of any kind or as an employment agency; (iii) the sale, at retail or wholesale, of any products or materials kept in the Demised Premises, by vending machine or otherwise; (iv) manufacturing purposes; (v) the rendition to the public of medical, dental or other diagnostic or therapeutic services; (vi) a restaurant, bar, or the sale of confectionery, tobacco, newspapers, magazines, soda, beverages, sandwiches, ice cream, baked goods or similar items, or the preparation, dispensing or consumption of food and beverages; (vii) the conduct of any business, occupation or activity which, in Landlord's reasonable judgment may (x) impair the reputation of the Buildings, (y) interfere with or disturb the occupancy of other tenants or occupants of the Buildings, or (z) create or fost▇▇ ▇▇ unusual risk to the security of the Buildings or of any of their tenants or occupants; (viii) the conduct of any business not engaged in by Tenant at the date of this lease, if the use of the Licensed Materials set out Demised Premises for such business shall conflict with any negative covenants as to use contained in any other lease of space in the Buildings entered into subsequent to the date of this Licence and lease but prior to the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee Demised Premises for such other business, provided that Landlord shall have notified Tenant of the existence of such negative covenants; or 18 (ix) printing and reproduction of materials for sale or for the purpose of rendering services to others. (b) Tenant shall not suffer or permit the Demised Premises or any part thereof to be liable used in any manner, or anything to be done therein, or suffer or permit anything to be brought into or kept in the Demised Premises, which would in any way (i) violate any laws or requirements of public authorities (subject to the right to contest such laws or requirements as provided in, and subject to the provisions of, Section 14.02), (ii) cause injury to the Buildings or any part thereof, (iii) constitute a public or private nuisance, (iv) impair the appearance of the exterior of the Buildings, (v) impair the use for normal purposes of any breach other area of the Buildings by Authorised Users of (or occasion physical discomfort to, or interfere with services required to be furnished by Landlord to Tenant or to) any of the provisions other tenants and occupants of the Buildings, or (vi) violate any of Tenant's other obligations under this Licence, including but not limited to the provisions set out belowlease. b(c) Authorised Users may not: iTenant shall not cause (or allow any of its contractors, agents or other persons or entities over whom or which it exercises a degree of control to cause) Remove or alter to occur within the author’s name(s) Demised Premises, or the publisher’s copyright notices Buildings, any discharge, spillage, uncontrolled loss, seepage or other means filtration of identification hazardous waste or oil or petroleum liquids or solids, asbestos, pcb, radioactive substances, methane, volatile hydrocarbons, industrial solvents, or any and all disclaimers as they appear other materials or substances which have in the Licensed Materials; ii) Systematically make print past caused or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyoneconstituted, or transmit any part of are in the Licensed Material (other than Metadata) by any means future found to anyonecause or constitute, other than an Authorised Usera health, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)safety or environmental hazard. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee shall use reasonable efforts to ensure that the Authorised Users are aware of the prohibitions on the use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s 's Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work; vi) make Make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) 4 shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee Tenant and Tenant's agents shall not commit or suffer to be committed any waste upon the Premises. Tenant and Tenant's agents shall not do or permit anything to be done in or about the Premises or Parking Area which will in any way obstruct or interfere with the rights of Landlord, or injure or annoy Landlord or its employees. Tenant and Tenant's agents shall not use reasonable efforts or allow the Premises to ensure that be used for any unlawful, immoral or any purpose not permitted by this Lease, nor shall Tenant or Tenant's agents cause, maintain, or permit any nuisance in, on or about the Authorised Users are aware Premises. Tenant and Tenant's agents shall not do or permit anything to be done in or about the Premises or Parking Area nor bring or keep anything in the Premises or Parking Area which will in any way increase the rate of any insurance upon the Premises or Parking Area or any part thereof or any of its contents, or cause a cancellation of any insurance policy covering the Premises or Parking Area or any part thereof or any of its contents, nor shall Tenant or Tenant's agents keep, use or sell or permit to be kept, used or sold in or about the Premises or Parking Area any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance upon the Premises or Parking Area or any part thereof or any of its contents is increased because of the prohibitions on acts or omissions of Tenant or Tenant's agents, Tenant shall pay, as Additional Rent, the use full cost of such increase; provided however this provision shall in no event be deemed to constitute a waiver of Landlord's right to declare a Default hereunder by reason of such increase or of any other rights or remedies of Landlord in connection with such increase. Tenant and Tenant's agents shall not place any loads upon the floor, walls, or ceiling of the Licensed Materials set out Premises which would endanger the Premises or the structural elements thereof, nor place any harmful liquids in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use drainage system of the Licensed MaterialsPremises. The Licensee No waste materials or refuse shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited dumped upon or permitted to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of remain upon any part of the Licensed Materials for Premises or Parking Area except in enclosed trash containers. No materials, supplies, equipment, finished products (or semi-finished products), raw materials, or other articles of any purpose other than that nature shall be stored upon, or be permitted by this Licence; iii) Prepare derivative works or downloadto remain on, mount or distribute any part portion of the Licensed Material Parking Area. Tenant shall not use, store on, dispose or allow the use, storage or disposal, of any Hazardous Materials, as that term is defined in Section 24.2, on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use portion of the Licensed Material Premises. Tenant shall indemnify, and hold Landlord, and its officers, directors, employees and agents harmless from and against any and all claims, losses, damages, liabilities or expenses (including, without limitation, attorneys' fees) arising in whole or in part); or vii) provide access to and/or permit use connection with a breach of the Licensed Content by anyoneobligations set forth herein. Tenant's obligation to defend, hold harmless and indemnify pursuant to this Section shall survive Lease Termination or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)expiration. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. (a) The Licensee Throughout the Term, Landlord shall use reasonable efforts to ensure that not further develop the Authorised Users are aware Property, other than consistent with the provisions of this Lease, and, without limiting the prohibitions on the use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee generality thereof, no such further development shall be liable for any breach by Authorised Users of any permitted if (1) the same would cause a violation of the provisions of this LicenceSection 4.8(b) hereof or Section 14.20 hereof, including but not limited or (2) the same would otherwise result in (i) an increase in the amount of any Additional Rent payable by Tenant hereunder, (ii) any other cost or expense being imposed upon Tenant or any Tenant Party, (iii) any reduction in the value of the Leased Premises to Tenant or any Tenant Party, (iv) parking or traffic flow on the provisions set out belowProperty being adversely affected from the perspective of Tenant or any Tenant Party, (v) any reduction in the function or utility of the Common Areas (or any portion thereof) from the perspective of Tenant or any Tenant Party. (b) Authorised Users may not: i) Remove Throughout the Term, Landlord shall not use, or alter permit the author’s name(s) or use of, the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials Property (or any part of them thereof) for any purpose whatsoever Prohibited Uses. The term “Prohibited Uses” shall mean (i) any use that emits an obnoxious odor, noise or incorporate sound that can be heard or smelled outside of the premises; (ii) any part use in violation of any Licensed Materials (whether in amended zoning regulations or unamended form) into any other work governmental restrictions applicable to the Property; (iii) any use that, by its nature, (even if such use is legally permissible) would result in parking or traffic flow on the Property being materially adversely affected from the perspective of Tenant or any Tenant Party; (iv) any operation primarily used as a warehouse or storage facility, assembling or manufacturing, distilling, refining, rendering, processing, smelting, agricultural or mining operations; (v) any mobile home park or sales, trailer court, labor camp, junk yard or stockyard; (vi) make any Commercial Use central laundry, dry cleaning plant or laundromat; provided, however, this prohibition shall not be applicable to on-site services oriented only to pickup and delivery by consumers; (vii) any automobile, truck, trailer or recreational vehicle sales, leasing, display, repair or body shop; (viii) any living quarters, sleeping apartments, hotel or lodging rooms; (xi) veterinary hospitals, animal raising or breeding facilities, animal boarding facilities or pet shops; (x) mortuaries or funeral homes; (xi) any establishment that sells, rents or exhibits pornographic materials; (xii) massage parlors or any form of sexually oriented business (including novelty merchandise sales); (xiii) bars, taverns or brew pubs; (xiv) flea markets, amusement or video arcades, computer game rooms, pool or billiard halls, bingo halls, dance halls, discos or night clubs; (xv) sales of paraphernalia for use with illicit drugs; (xvi) carnivals, amusement parks or circuses; (xvii) pawn shops, auction houses, second hand stores, consignment shops, army/navy surplus stores or gun shops; (xviii) gambling facilities or sports betting parlor; (xix) churches, synagogues or other places of worship; (xx) assembly halls or meeting facilities; (xxi) technical or vocational schools or any other operation primarily engaged in education or training activities; (xxii) medical clinics, abortion clinics, medical laboratories or screening facilities; (xxiii) any agency (public or private) providing health, welfare, social or human services, or (xxiv) tattoo parlors, fortune telling or spiritual readings; (xxv) facilities that collect donated goods and products; (xxvi) bowling alleys, skating rinks, archery or gun ranges, (xxvii) postal facilities, tax collectors, tag agencies, jails or detention centers, courthouses or any other form of agency dealing with civil authority. Notwithstanding the foregoing, the term “Prohibited Uses” shall not include any use which is permitted under a third party tenant lease of space in the Building which is in effect as of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)Commencement Date. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. aTenant further covenants and agrees that Tenant shall not commit waste, overload the Base Building and Tenant's Building Systems (as that term is defined in Section 7.2.1 below) The Licensee shall or subject the Premises to use reasonable efforts that would damage the Premises or use, or suffer or permit any person or persons to ensure that use, the Authorised Users are aware Premises or any part thereof for any use or purpose contrary to the provisions of the prohibitions Rules and Regulations set forth in Exhibit D, attached hereto (the "Rules and Regulations"), or in violation of any applicable Laws. Tenant's use shall not result in an occupancy density for the Premises which is greater than the density allowed by applicable Laws. No Tenant Party (as that term is defined in Section 10.1 below) shall do or permit anything to be done in or about the Premises or the Project which will in any way damage the reputation of the Project, create extraordinary fire hazards, or result in an increased rate of insurance on the Project or its contents, or obstruct or interfere with the normal and customary use or operation of the Project by Landlord or other tenants and/or occupants (including, without limitation, by means of noise, vibration, odor of other undesirable effect emanating from the Premises or any machine or other installation therein or from any of Tenant's Off-Premises Equipment) or the rights of other tenants or occupants of the Building, or injure or annoy them or use or allow the Premises, Tenant's Building Systems or any of Tenant's Off-Premises Equipment to be used for any improper, unlawful or objectionable purpose, nor shall Tenant cause, maintain or permit any nuisance in, on or about the Premises or the Project. Tenant shall not use any substantial portion of the Premises for a "call center," any other telemarketing use, or any credit processing use. Tenant shall comply with, and Tenant's rights and obligations under this Lease and Tenant's use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee Premises shall be liable for any breach subject and subordinate to, all Underlying Documents now or hereafter affecting the Project, and, upon request from Landlord, Tenant shall promptly recognize such Underlying Documents by Authorised Users executing a commercially reasonable form of any of the provisions of this Licence, including but not limited to the provisions set out belowrecognition. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee Tenant shall use reasonable efforts to ensure that the Authorised Users are aware of the prohibitions not commit or allow any waste and shall carry on the use of the Licensed Materials set out Permitted Use in this Licence strict accordance with all Applicable Laws and the Licensee shall use Landlord’s reasonable endeavours rules and regulations governing the same. Objectionable odors (including those inherent to ensure that cannabis manufacturing and/or its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users of any of the provisions of this Licence, usage and/or storage (including but not limited to as caused by terpenes), which the provisions set out below. bTenant acknowledges are “objectionable”) Authorised Users may not: i) Remove from the Premises shall, at the Tenant’s sole expense, be exhausted, filtered or alter otherwise managed, in such a manner as to: prevent their affecting the author’s name(s) air quality at any adjacent or neighboring properties in a material way (including parts of the publisher’s copyright notices Greater Lands that do not form part of the Premises (the “Excluded Greater Lands”)), or other means short circuiting into any fresh air vents, all in a manner which is compliant with Applicable Laws. If the Landlord reasonably determines that objectionable odors are adversely affecting the air on any adjacent or neighboring properties contrary to Applicable Law (including the Excluded Greater Lands), or short circuiting into any fresh air vents, or forming a legal nuisance to neighboring properties (or a material interference with the Excluded Greater Lands), and the Tenant, upon request by the Landlord, fails to forthwith take whatever steps are necessary to rectify such issue within a reasonable period of identification time, or if the situation cannot be resolved in compliance with Applicable Laws and to the satisfaction of the Landlord, in its reasonable discretion, the Landlord shall have, the right, but not the obligation, to enter the Premises and rectify the situation and the Tenant shall pay to the Landlord, promptly upon demand, any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than reasonable costs which may be incurred by the LicenseeLandlord in completing such rectifying work, together with an administration fee of fifteen percent (15%) of such costs. The Tenant shall not use the Premises in a manner which does or could result in excessive demands being placed on the Building Systems; it being acknowledged and agreed, however, that the Tenant and Landlord have consulted on the Tenant’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyonePremises for the Permitted Use and such use does not in itself and shall not be deemed in itself to violate this paragraph. Notwithstanding the foregoing, or transmit any part of Tenant shall indemnify and hold harmless the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B Landlord (including by way in respect of inter-library lending)all legal fees on a solicitor and his own client basis) related to any claim of nuisance. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee Tenant and Tenant's agents shall use reasonable efforts not commit or suffer to ensure that be committed any waste upon the Authorised Users are aware Premises. Tenant and Tenant's agents shall not do or permit anything to be done in or about the Premises or Common Area which will in any way obstruct or interfere with the rights of any other tenants of the prohibitions Building, other authorized users of the Common Area, or occupants of neighboring property, or injure or annoy them. Tenant shall not conduct or permit any auction or sale open to the public to be held or conducted on or about the Premises or Common Area. Tenant and Tenant's agents shall not use or allow the Premises to be used for any unlawful, immoral or hazardous purpose or any purpose not permitted by this Lease, nor shall Tenant or Tenant's agents cause, maintain, or permit any nuisance in, on or about the Premises. Tenant and Tenant's agents shall not do or permit anything to be done in or about the Premises nor bring or keep anything in the Premises which will in any way increase the rate of any insurance upon any portion of the Project or any of its contents, or cause a cancellation of any insurance policy covering any portion of the Project or any of its contents, nor shall Tenant or Tenant's agents keep, use or sell or permit to be kept, used or sold in or about the Premises any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance upon any portion of the Project or any of its contents is increased because of Tenant's particular use of the Licensed Materials set out Premises or that of Tenant's agents, Tenant shall pay, as Additional Rent, the full cost of such increase; provided, however this provision shall in this Licence and the Licensee shall use reasonable endeavours no event be deemed to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect constitute a waiver of their access Landlord's right to and use declare a default hereunder by reason of the Licensed Materialsact or conduct of Tenant or Tenant's agents causing such increase or of any other rights or remedies of Landlord in connection therewith. The Licensee Tenant and Tenant's agents shall not place any loads upon the floor, walls or ceiling of the Premises which would endanger the Building or the structural elements thereof or of the Premises, nor place any harmful liquids in the drainage system of the Building or Common Area. No waste materials or refuse shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited dumped upon or permitted to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of remain upon any part of the Licensed Materials Project except in enclosed trash containers designated for that purpose by Landlord. No materials, supplies, equipment, finished products (or semi-finished products), raw materials, or other articles of any purpose other than that nature shall be stored upon, or be permitted by this Licence; iii) Prepare derivative works or downloadto remain on, mount or distribute any part portion of the Licensed Material on any electronic system or network, including without limitation Project outside the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)Premises. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. Notwithstanding any other provision of this Lease, Tenant shall not use, or suffer or permit the use or occupancy of, or suffer or permit anything to be done in or anything to be brought into or kept in or about the Premises or the Building or any part thereof (including, without limitation, any materials, appliances or equipment used in the construction or other preparation of the Premises and furniture and carpeting): (a) The Licensee shall use reasonable efforts to ensure that the Authorised Users are aware which would violate any of the prohibitions on covenants, agreements, terms, provisions and conditions of this Lease or the use Rules and Regulations or that are otherwise applicable to or binding upon the Premises; (b) which, in the reasonable judgment of Landlord shall in any way (i) impair the appearance or reputation of the Licensed Materials set out in this Licence and Building; or (ii) impair, interfere with or otherwise diminish the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users quality of any of the provisions of this Licence, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) Building services or the publisher’s copyright notices proper and economic heating, cleaning, ventilating, air conditioning or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part servicing of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works Building or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyonePremises, or transmit any part with the use or occupancy of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing usesother areas of the Building, or occasion discomfort, inconvenience or annoyance, or injury or damage to any occupants of the Premises or other tenants or occupants of the Building; (iii) which is inconsistent with the maintenance of the Building as a comparable first-class life sciences building in Boston in the quality of its maintenance, use, or occupancy; (iv) adversely affect the LEED relating to Building Design and Construction (as defined below) (or similar) certifiability of the Building or any improvements therein or any LEED relating to Building Design and Construction or similar certifications previously obtained with respect to the Building; or (v) which would violate any then current exclusive use or right granted by Landlord to any tenant or occupant of the Building (Landlord agreeing to provide notice of same within ten (10) business days following Tenant’s written request therefor); or (c) which would violate any Excluded Use set forth on Exhibit 11 attached hereto. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇Tenant shall not install or use any electrical or other equipment of any kind which, in the reasonable judgment of Landlord, might cause any such impairment, interference, discomfort, inconvenience, annoyance or injury.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee Tenant and Tenant's agents shall not commit or suffer to be committed any waste upon the Premises. Tenant and Tenant's agents shall not do or permit anything to be done in or about the Premises which will unreasonably obstruct or interfere with the rights of any occupants of neighboring property, or injure or annoy them. Tenant shall not conduct or permit any auction or sale open to the public to be held or conducted on or about the Premises. Tenant and Tenant's agents shall not use reasonable efforts or allow the Premises to ensure that be used for any unlawful purpose or any purpose not permitted by this Lease, nor shall Tenant or Tenant's agents cause, maintain, or permit any nuisance in, on or about the Authorised Users are aware Premises. Tenant and Tenant's agents shall not do or permit anything to be done in or about the Premises nor bring or keep anything in the Premises which will cause a cancellation of any insurance policy covering the Premises or any part thereof or any of its contents, nor shall Tenant or Tenant's agents keep, use or sell or permit to be kept, used or sold in or about the Premises any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance upon the Premises or any part thereof or any of its contents is increased because of the prohibitions on acts or omissions, direct or indirect, of Tenant or Tenant's agents, Tenant shall pay, as Additional Rent, the use full cost of such increase; provided however this provision shall in no event be deemed to constitute a waiver of Landlord's right to any other rights or remedies of Landlord in connection with such increase. Tenant and Tenant's agents shall not place any loads upon the floor, walls or ceiling of the Licensed Materials set out Premises which would endanger the Premises or the structural elements thereof, nor place any harmful liquids in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use drainage system of the Licensed MaterialsPremises. The Licensee No waste materials or refuse shall be liable for dumped upon or permitted to remain upon any breach by Authorised Users of any part of the provisions Premises except in enclosed trash containers. Tenant shall not allow any activity which in the reasonable opinion of this LicenceLandlord is detrimental to the operation of other buildings located upon real property owned by Landlord adjacent to the Premises, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices any picketing, work stoppage, or other means concerted activity. Landlord shall have the right to require Tenant, at Tenant's own expense and within a reasonable period of identification time, to use Tenant's best efforts to terminate or control any and all disclaimers as they appear in such picketing, work stoppage or other concerted activity to the Licensed Materials; ii) Systematically make print extent necessary to eliminate any interference with the operation or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted such tenants. Failure by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User Tenant to use its best efforts to do so; v) Alter, edit, abridge so shall be a Default by Tenant. Nothing contained in this paragraph shall be construed as placing Landlord in an employer-employee relationship with any of Tenant's employees or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into with any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise employees who may be permitted under Appendix B (including by way of inter-library lending)involved in such activity. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. Tenant shall not use, or suffer or permit the use --------------- of, or suffer or permit anything to be done in or anything to be brought into or kept in, the Demised Premises or any part thereof (i) which would violate any of the covenants, agreements, terms, provisions and conditions of this Lease, (ii) for any unlawful purposes or in any unlawful manner, or (iii) which, in the reasonable judgment of Landlord shall in any way (a) The Licensee shall use reasonable efforts impair or tend to ensure that impair the Authorised Users are aware appearance or reputation of the prohibitions on Building, (b) impair or interfere with or tend to impair or interfere with any of the Building services or the proper and economic heating, cleaning, air conditioning or other servicing of the Building or Demised Premises, or with the use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part areas of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyoneBuilding, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior occasion discomfort, inconvenience or annoyance to carrying out or attempting to carry out any of the foregoing usesother tenants or occupants of the Building, whether through the transmission of noise or odors or otherwise. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5Without limiting the generality of the foregoing, no food shall be prepared or served for consumption on or about the Demised Premises; no intoxicating liquors or alcoholic beverages shall be sold on or about the Demised Premises; no lottery tickets (even where the sale of such tickets is not illegal) shall continue be sold and no gambling, betting or wagering shall otherwise be permitted on or about the Demised Premises; no loitering shall be permitted in or about the Demised Premises; and no loading or unloading of supplies or other material to apply after termination or from the Demised Premises shall be permitted on the Land except at times and in locations to be designated by Landlord. The Demised Premises shall be maintained in a sanitary condition, and all kept free of this Licence for any reasonrodents and vermin. All trash and rubbish shall be suitably stored in the Demised Premises or other locations designated by Landlord from time to time.

Prohibited Uses. (a) The Licensee Notwithstanding any other provision of this Lease, Tenant shall not use reasonable efforts to ensure that the Authorised Users are aware Premises or the Building, or any part thereof, or suffer or permit the use or occupancy of the prohibitions on Premises or the Building or any part thereof by any of the Tenant Parties (i) in a manner which would violate any of the covenants, agreements, terms, provisions and conditions of this Lease or any Permitted Encumbrance; (ii) for any unlawful purposes or in any unlawful manner; (iii) which, in the reasonable judgment of Landlord (taking into account the use of the Licensed Materials set out in this Licence Building as a combination office and laboratory building and the Licensee Permitted Uses) shall use reasonable endeavours to ensure that its Authorised Users do not breach (A) impair the prohibitions set out in this Licence in respect of their access to and use appearance or marketability of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users Building; (B) impair, interfere with or otherwise diminish the quality of any of the provisions Building services or the proper and economic heating, cleaning, ventilating, air conditioning or other servicing of this Licencethe Building or Premises, including but not limited or the use or occupancy of any of the Common Areas; (C) occasion discomfort, inconvenience or annoyance in any material respect, or cause any injury or damage to any other occupants of the Property or neighboring properties or their property; or (D) cause harmful air emissions or any unusual or other objectionable odors, noises or emissions to emanate from the Premises; (iv) in a manner which is inconsistent with the operation and/or maintenance of the Building as a first-class combination office and laboratory facility; or (v) for any fermentation processes whatsoever other than biological manufacturing of protein therapeutics. (b) With respect to the provisions set out below. b) Authorised Users may use and occupancy of the Premises and the Common Areas, Tenant will not: : (i) Remove place or alter the author’s name(s) or the publisher’s copyright notices maintain any trash, refuse or other means articles in any vestibule or entry of identification the Premises, on the footwalks or corridors adjacent thereto or elsewhere on the exterior of the Premises, nor, subject to Section 12 below, place or maintain any signage on the exterior of the Premises, nor obstruct any driveway, corridor, footwalk, parking area, mall or any and all disclaimers as they appear in the Licensed Materials; other Common Areas; (ii) Systematically make print permit undue accumulations of or electronic copies burn garbage, trash, rubbish or other refuse within or without the Premises; (iii) permit the parking of multiple extracts or make multiple copies vehicles so as to interfere with the use of any part driveway, corridor, footwalk, parking area, or other Common Areas; (iv) receive or ship articles of any kind outside of those areas reasonably designated by Landlord; (v) conduct or permit to be conducted any auction, going out of business sale, bankruptcy sale (unless directed by court order), or other similar type sale in or connected with the Premises; (vi) use the name of the Licensed Materials for Building, the Property, Landlord, or any purpose of Landlord’s affiliates or subsidiaries or any photograph, film, drawing, or other than that permitted by this Licence; iii) Prepare derivative works depiction or download, mount or distribute any part representation of the Licensed Material on any electronic system or network, including without limitation Building and/or the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials Property or any part of them for thereof, which contains signage or distinctive architectural characteristics that cause the scene photographed, filmed, drawn, depicted, or represented to be identifiable as being the Building and/or the Property, in any purpose whatsoever publicity, promotion, trailer, press release, advertising, printed, or incorporate display materials without Landlord’s prior written consent; or (vii) except in connection with Tenant’s Work and/or Alterations (hereinafter defined) approved by Landlord, cause or permit any part of hole to be drilled or made in any Licensed Materials (whether in amended exterior, load bearing or unamended form) into any other work vi) make any Commercial Use structural wall of the Licensed Material Building. (c) At all times that animals are transported within the Common Areas, they shall be transported in whole an appropriate cage or in part); or vii) provide access other container. At no time shall any animals, animal waste, food or supplies relating to and/or permit use of the Licensed Content by anyoneanimals be brought into, transported through, or transmit any part of delivered to the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇▇ Street entrance of the Building.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee uses prohibited under this Lease shall use reasonable efforts to ensure that the Authorised Users are aware of the prohibitions on the include, without limitation, use of the Licensed Materials set out Premises or a portion thereof for (i) offices of any agency or bureau of the United States or any state or political subdivision thereof, unless Landlord has agreed to permit such uses within other portions of the office component of the Project; (ii) offices or agencies of any foreign governmental or political subdivision thereof, unless Landlord has agreed to permit such uses within other portions of the office component of the Project; (iii) offices of any health care professionals or service organization; (iv) schools or other training facilities which are not ancillary to corporate, executive or professional office use; (v) retail or restaurant uses; and (vi) uses prohibited under the Underlying Documents. Tenant's use shall not result in an occupancy density for the Premises which is greater than the density permitted by Applicable Laws and zoning requirements, and further provided that Landlord shall not be obligated to make any changes to the Base Building or Common Areas to accommodate Tenant's occupancy density. Tenant further covenants and agrees that it shall not use, or suffer or permit any person or persons to use, the Premises or any part thereof for any use or purpose contrary to the rules and regulations attached to this Licence Lease as Exhibit D ("Rules and Regulations"), provided, however, Landlord shall not enforce, change or modify the Rules and Regulations in a discriminatory manner and Landlord agrees that the Rules and Regulations shall not be unreasonably modified or enforced in a manner which will unreasonably interfere with the normal and customary conduct of Tenant's business. In the event of any conflict between the Rules and Regulations and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users of any of the other provisions of this LicenceLease, including but the other provisions of this Lease shall control. Tenant shall not limited do or permit anything to be done in or about the provisions set out below. b) Authorised Users may not: i) Remove Premises which will in any material way obstruct or alter interfere with the author’s name(s) rights of other tenants or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part occupants of the Licensed Materials Project, or allow the Premises to be used for any purpose other than that permitted by this Licence; iii) Prepare derivative works unlawful purpose, nor shall Tenant cause, maintain or downloadpermit any nuisance in, mount on or distribute any part of about the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)Premises. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. 9.1 Not to use the Premises for any business connected with the Motor Trade or for any public meeting exhibition or entertainment or as a hotel club or amusement arcade or permit any musical instrument radio television or other sound emitting equipment to be operated so as to be audible from outside the Premises 9.2 Not to engage in any works or other operations or permit or store on the Property any goods or other articles which may by reason of smell infection or radioactivity affect any other goods or articles (of whatever kind and however sensitive) elsewhere upon the Estate or generate an excessive degree of noise and/or dust which may constitute a breach of the planning consent FIFTH SCHEDULE (a) Title numbered BK260648 in H M Land Registry (b) Title numbered BK291692 in H M Land Registry (relating to the Common Parts) (c) The Licensee shall use reasonable efforts Registered Transfers (d) The Outline Planning Consent Number 622867 issued by Bracknell Forest Borough Council on 7th October 1997. SIXTH SCHEDULE Guarantee provisions 1. That the Tenant will at all times during the Term pay the Rents and all other sums covenanted to ensure be paid by the Tenant at the respective times and in the manner appointed for payment thereof and also will duly perform and observe and keep the several covenants stipulations and conditions on the part of the Tenant to be performed and observed and kept and that the Authorised Users are aware Guarantor will pay and make good to the Landlord all losses costs and expenses sustained by the Landlord through the default of the prohibitions on the use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence Tenant in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users of any of the provisions before-mentioned matters PROVIDED ALWAYS that any neglect or forbearance of this Licence, including but not limited the Landlord in endeavouring to obtain payment of the provisions set out below. b) Authorised Users may not: i) Remove or alter Rents and other sums as and when the author’s name(s) or the publisher’s copyright notices or other means of identification same shall become due or any and all disclaimers as they appear in delay on the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for Landlord to take any purpose other than that permitted by this Licence; iii) Prepare derivative works steps to enforce performance or download, mount observance of the said several covenants stipulations and conditions shall not release or distribute in any way lessen or affect the liability of the Guarantor under the guarantee on the part of the Licensed Material on any electronic system Guarantor hereinbefore contained 2. That if the Tenant being an individual shall become bankrupt or network, including without limitation if the Internet Tenant for the time being is a company and shall enter into liquidation and the World Wide Web, other than Tenant's trustee in bankruptcy or the Liquidator of the Tenant shall disclaim this Lease and if the Landlord shall within three months after such disclaimer by notice require the Licensee’s Secure Network approved Guarantor or the Guarantor's personal representatives or assigns to accept a lease of the Premises for a term commensurate with the residue which if there had been no disclaimer would have remained of the Term at the same Rents and under the like covenants conditions provisions agreements and declarations as are reserved by and contained in advance by The Company this Lease (the said new lease and the rights and liabilities thereunder to take effect from the date of Biologists, except where expressly permitted the said disclaimer) then and in such case the Guarantor or the Guarantor's personal representatives or assigns shall accept such lease accordingly and execute a counterpart thereof and pay the Landlord's solicitors' costs and disbursements of and incidental thereto 3. This guarantee shall enure for the benefit of the successors and assigns of the Landlord under this Licence;Lease without the necessity for any assignment of the benefit thereof iv) Sell or resell 4. This guarantee is also to take effect immediately on the Licensed Materials unless The Company assignment of Biologists has given prior written permission the Lease to the Tenant under clause 5.8 hereof and is to remain in force so long as and to the extent that the Tenant is not released by law from liability for the Authorised User Tenant's covenants in the Lease 5. In the context of these guarantee provisions reference to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of Tenant are to the Licensed Material assignee only (in whole or its capacity as Tenant) with respect to whom his guarantee is given THE COMMON SEAL of T A FISHER & SONS LIMITED was hereunto affixed in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email presence of:- ▇▇▇▇▇▇▇▇ /s/J. Fisher Secretary /s/M. Stewart THE COMMON SEAL of WELLINGTON ▇▇▇▇ ▇▇▇▇@GEMENT LIMITED w▇▇ ▇▇▇▇▇▇▇o affixed in the presence of:- Director /s/J. Fisher Secretary /s/M. Stewart EXECUTED AS A DEED by SAVILLE S▇▇▇.▇▇▇ (▇K) LIMITED by ▇▇▇▇▇▇▇▇ /s/Christopher A. Hanson ▇▇▇▇▇▇ary /s/Lisa Miller EXECUTED AS A DEED ▇▇ ▇▇▇▇▇▇▇ ▇▇▇▇▇▇▇ ▇LC by Directo▇ /▇/▇▇▇▇ ▇. Boyle, III Secretary /▇/▇▇▇▇ Miller ▇▇▇▇▇NE OFFICE SPECIFICAT▇▇▇ UNITS 35 - 38 WELLINGTON BUSINESS PARK ▇▇▇▇▇ ▇▇▇▇ CROWTHORNE BERKSHIRE. Approximate Schedule of Accommodation m2 (ft2) Unit Nett Int. 36 289 (3106) 37 317 (3407) 38* 317 (3407) The Buildings: Generally comprise the construction of a two storey office unit with traditional brick elevations; in-situ concrete ground floor slab; pre-cast concrete first floor and stairs; structural steel frame; pitched roof covered with BSC Colourcoat HP 200 (or equal) plastic coated steel sheeting; double glazed windows and doors; raised particle access floors; air conditioning; mechanical, electrical and sanitary installations; floor, wall and ceiling finishes. *Unit 38 shell construction @ Ground Floor. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee uses prohibited under this Lease shall use reasonable efforts to ensure that the Authorised Users are aware of the prohibitions on the include, without limitation, use of the Licensed Materials set out Premises or a portion thereof for (i) offices of any agency or bureau of the United States or any state or political subdivision thereof; (ii) offices or agencies of any foreign governmental or political subdivision thereof; (iii) offices of any health care professionals or service organization (but excluding any health care professionals engaged in this Licence and the Licensee business of life sciences research); (iv) schools or other training facilities which are not ancillary to corporate, executive or professional office use; (v) retail or restaurant uses; or (vi) communications firms such as radio and/or television stations. Tenant shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect allow occupancy density of their access to and use of the Licensed MaterialsPremises which is greater than one (1) person for each 150 square feet of the Premises. The Licensee Tenant further covenants and agrees that Tenant shall be liable not use, or suffer or permit any person or persons to use, the Premises or any part thereof for any breach by Authorised Users of any of use or purpose contrary to the provisions of this Licencethe Rules and Regulations set forth in Exhibit D, including but not limited to attached hereto, or in violation of the provisions set out below. b) Authorised Users may not: i) Remove or alter laws of the author’s name(s) United States of America, the State of California, or the publisher’s copyright notices ordinances, regulations or requirements of the local municipal or county governing body or other means lawful authorities having jurisdiction over the Project) including, without limitation, any such laws, ordinances, regulations or requirements relating to hazardous materials or substances, as those terms are defined by applicable laws now or hereafter in effect. Tenant shall not do or permit anything to be done in or about the Premises which will in any way materially damage the reputation of identification the Project or obstruct or interfere with the rights of other tenants or occupants of the Building, or injure or annoy them or use or allow the Premises to be used for any improper, unlawful or objectionable purpose, nor shall Tenant cause, maintain or permit any nuisance in, on or about the Premises. Tenant shall comply with all recorded covenants, conditions, and all disclaimers as they appear in restrictions now or hereafter affecting the Licensed Materials; ii) Systematically make print or electronic Project and Landlord shall, upon request from Tenant, provide Tenant with copies of multiple extracts or make multiple all recorded covenants, conditions and restrictions currently affecting the Project and will notify Tenant and provide copies to Tenant of any part of future covenants, conditions, and restrictions affecting the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)Project. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. Tenant further covenants and agrees that Tenant shall not use, or suffer or permit any person or persons to use, the Premises or any part thereof for any use or purpose in violation of Legal Requirements. Tenant will faithfully observe and comply with (i) the Building Rules and Regulations annexed hereto as Exhibit D-1 and (ii) the “Green Lease” provisions annexed hereto as Exhibit D-2 (collectively, the “Rules and Regulations”), and further reasonable Rules and Regulations as Landlord hereafter at any time or from time to time may make and communicate in writing to Tenant, which in the reasonable judgment of Landlord shall be necessary for the reputation, safety, care or appearance of the Building, the Project or the preservation of good order therein, or the operation or maintenance of the Building, the Project or the equipment thereof, provided, however, that in the case of any conflict between the provisions of this Lease and any such future rules and regulations, the provisions of this Lease shall control. Nothing contained in this Lease shall be construed to impose upon Landlord any duty or obligation to enforce the Rules and Regulations or the terms, covenants or conditions in any other lease as against any other tenant and Landlord shall not be liable to Tenant for violation of the same by any other tenant, its servants, employees, agents, contractors, visitors, invitees or licensees. Tenant shall not do or permit anything to be done in or about the Premises which will in any way (a) The Licensee shall use reasonable efforts to ensure that damage the Authorised Users are aware reputation of the prohibitions on Project; (b) impair, interfere with or otherwise diminish the use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users quality of any of the provisions Building services or the proper and economic heating, cleaning, ventilating, air conditioning or other servicing of this Licencethe Building or Premises, including but or the use of any of the Common Areas; (c) obstruct or interfere with the rights of other tenants or occupants of the Building, or injure or annoy them; (d) use or allow the Premises to be used for any improper, unlawful or objectionable purpose; (e) cause harmful air emissions or laboratory odors or objectionable odors, noises or emissions to emanate from the Premises; (f) increase such insurance rates on the Building or on property located therein over that applicable when Tenant first took occupancy of the Premises hereunder; or (g) cause, maintain or permit any nuisance in, on or about the Premises. Furthermore, Tenant shall not limited to the provisions set out below. b) Authorised Users may not: (i) Remove place or alter the author’s name(s) or the publisher’s copyright notices maintain any garbage, trash, rubbish or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or downloadrefuse (collectively, mount or distribute any part of the Licensed Material on any electronic system or network“Trash”), including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials signage (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). cArticle 23 below) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out other articles in any vestibule or entry of the foregoing usesPremises, on the footwalks or corridors adjacent thereto or elsewhere on the exterior of the Premises, nor obstruct any driveway, corridor, footwalk, parking area, mall or any other Common Areas; (ii) permit undue accumulations of or burn Trash within or without the Premises; (iii) permit the parking of vehicles so as to interfere with the use of any driveway, corridor, footwalk, parking area, or other Common Areas; (iv) receive or ship articles of any kind outside of those areas reasonably designated by Landlord; (v) conduct or permit to be conducted any auction, going out of business sale, bankruptcy sale (unless directed by court order), or other similar type sale in or connected with the Premises; or (vi) permit or keep any animals other than trained certified service animals in the Building. Email Tenant shall comply with, and Tenant’s rights and obligations under the Lease and T▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇’s use of the Premises shall be subject and subordinate to, all governmental permits and approvals affecting the Project and all recorded easements, covenants, conditions, and restrictions now or hereafter affecting the Project, including any Underlying Documents.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee shall use reasonable efforts to ensure that the Authorised Users are aware of the prohibitions on the use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited to the provisions set out below.use b) Except where this Licence provides otherwise, Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work, except where expressly permitted under this Licence; vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.. (…) Copyright and Permissions

Prohibited Uses. (a) The Licensee Notwithstanding any other provision of this Lease, Tenant shall not use reasonable efforts to ensure that the Authorised Users are aware Premises or the Building, or any part thereof, or suffer or permit the use or occupancy of the prohibitions on Premises or the use Building or any part thereof by any of the Licensed Materials set out Tenant Parties (hereinafter defined) (i) in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use a manner which would violate any of the Licensed Materials. The Licensee shall be liable covenants, agreements, terms, provisions and conditions of this Lease or otherwise applicable to or binding upon the Premises; (ii) for any breach by Authorised Users unlawful purposes or in any unlawful manner; (iii) in a manner which, in the reasonable judgment of Landlord shall (a) impair the appearance or reputation of the Building; (b) impair, interfere with or otherwise diminish the quality of any of the provisions Building services or the proper and economic heating, cleaning, ventilating, air conditioning or other servicing of this Licencethe Building or Premises; or (c) cause harmful air emissions or any unusual or other objectionable odors, including but not limited noises or emissions to emanate from the Premises; (iv) in a manner which is inconsistent with the operation and/or maintenance of the Building as a first-class office and laboratory building; (v) for any fermentation processes except in the ordinary course of Tenant’s business and then only if adequately vented in Landlord’s reasonable judgment (it being understood and agreed that in no event shall there be fermentation for the purpose of creating alcoholic beverages for human consumption); (vi) to operate a vivarium in excess of 3,500 square feet; or (vii) in a manner which shall increase such insurance rates on the Building or on property located therein over that applicable when Tenant first took occupancy of the Premises hereunder. Notwithstanding any other provision herein to the provisions set out belowcontrary, Tenant shall be responsible for all liabilities, costs and expenses arising from or in connection with the compliance of the Premises with the Americans with Disabilities Act, 42 U.S.C. § 12101, et seq., and any state and local accessibility laws, codes, ordinances and rules (collectively, and together with regulations promulgated pursuant thereto, the “ADA”), and Tenant shall defend, indemnify and hold Landlord and the Landlord Parties harmless from and against any Claims arising from any such failure the Premises to comply with the ADA. Landlord agrees that Landlord’s Base Building Work shall be constructed in conformance with the ADA. In the event Landlord’s Base Building Work is not constructed in conformance with the ADA in effect as of the date Landlord commences the Landlord’s Base Building Work, and provided Tenant provides Landlord written notice thereof within three (3) months after the Commencement Date, and provided Landlord does not dispute Tenant’s determination of non-compliance, Landlord shall, as Tenant’s sole and exclusive remedy, address any such non-compliance of Landlord’s Base Building Work (and expressly not any Tenant Improvements or any modifications or alterations of Landlord’s Base Building Work that are made necessary as a result of Tenant Improvements, which such modifications or alterations are Tenant’s sole responsibility and cost). (b) Authorised Users may With respect to the use and occupancy of the Premises and the Common Areas, Tenant will not: : (i) Remove place or alter the author’s name(smaintain any signage (except as may be permitted by Section 12 below), Trash (hereinafter defined) or other articles in any vestibule or entry of the publisher’s copyright notices Premises, on the footwalks or corridors adjacent thereto or elsewhere on the exterior of the Premises, nor obstruct any driveway, corridor, footwalk, Parking Area, or any Common Areas; (ii) permit undue accumulations of or burn garbage, trash, rubbish or other means refuse (collectively, “Trash”) within or without the Premises; (iii) permit the parking of identification vehicles so as to interfere with the use of any driveway, corridor, footwalk, or parking area; (iv) receive or ship articles of any kind outside of those areas reasonably designated by Landlord; (v) conduct or permit to be conducted any auction, going out of business sale, bankruptcy sale (unless directed by court order), or other similar type sale in or connected with the Premises; (vi) use the name of Landlord, or any and all disclaimers as they appear of Landlord’s affiliates or subsidiaries in any publicity, promotion, trailer, press release, advertising, printed, or display materials without Landlord’s prior written consent (which may be withheld in Landlord’s sole discretion); (vii) except in connection with any vivarium, permit any animals other than service animals in the Licensed Materials; iiBuilding; or (viii) Systematically make print except in connection with Alterations (hereinafter defined) approved by Landlord, cause or electronic copies of multiple extracts permit any hole to be drilled or make multiple copies of made in any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.Building

Prohibited Uses. a) The Licensee Tenant shall use reasonable efforts not cause, suffer or permit the Premises or any part thereof to ensure that be used at any time during the Authorised Users are aware Term for any of the prohibitions on following sales, businesses or activities: (i) any retail or wholesale sales activities; (ii) any auction; (iii) any vending machines or other coin operated machines, entertainment or games machines or any other mechanical or electrical serving or dispensing machines or devices whatsoever or the use sale or supply of food or beverages (other than food or beverages such as are routinely served in office premises without charge to employees such as coffee and soft drinks) unless expressly permitted in writing by Landlord, in its sole discretion; (iv) any sale of tickets for theatre or other entertainment events or lottery tickets; (v) any business which would result in people waiting in Common Facilities to enter the Premises; (vi) any type of business or business practice which would, in the sole opinion of Landlord, tend to lower the character or image of the Licensed Materials set out Project or any portion thereof; (vii) any use which in any way contravenes any restrictive covenants in leases granted by Landlord; Tenant covenants and agrees that it will not carry on in the Premises any business which will in any way place Landlord in breach of any such restrictive covenants and Tenant will indemnify and save Landlord harmless from and against all actions, claims, demands and costs with respect thereto; this Licence and subsection (vii) shall not be interpreted to prevent Tenant from carrying on in the Licensee shall use reasonable endeavours Premises any business to ensure that its Authorised Users do the extent expressly permitted pursuant to section 8.1 hereof; or (viii) any business or activity not breach the prohibitions set out in this Licence in respect of their access to and use compliance with all Laws, The inclusion of the Licensed Materialsforegoing provisions of this section 8.5 shall not be deemed to be a representation or warranty of Landlord that any of the foregoing activities will not be authorized by Landlord to be conducted on any part of the Project. The Licensee Tenant shall be liable for forthwith, upon the request of Landlord, discontinue any business, conduct or practice carried on or maintained in or about the Premises, which, in Landlord’s sole opinion, may damage or reflect unfavourably upon Landlord, the Project, or any other tenants or occupants thereof. If, in the opinion of Landlord, Tenant is in breach by Authorised Users of any of the provisions of this Licencesection 8.5, including but not limited to the provisions set out belowTenant shall immediately discontinue such use upon Landlord’s written request. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. (a) The Licensee Notwithstanding any other provision of this Lease, Tenant shall not use reasonable efforts to ensure that the Authorised Users are aware Premises or the Building, or any part thereof, or suffer or permit the use or occupancy of the prohibitions on Premises or the use Building or any part thereof by any of the Licensed Materials set out Tenant Parties (hereinafter defined) (i) in a manner which would violate any of the covenants, agreements, terms, provisions and conditions of this Licence Lease or otherwise applicable to or binding upon the Premises; (ii) in a manner which, in the reasonable judgment of Landlord (taking into account the Building for office use and the Licensee Permitted Uses) shall use reasonable endeavours to ensure that its Authorised Users do not breach (a) impair the prohibitions set out in this Licence in respect of their access to and use appearance or reputation of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users Building; (b) impair, interfere with or otherwise diminish the quality of any of the provisions Building services or the proper and economic heating, cleaning, ventilating, air conditioning or other servicing of this Licencethe Building or Premises, including but not limited or the use of any of the Common Areas; (c) occasion discomfort, inconvenience or annoyance in any material respect, or cause any injury or damage to any occupants of the Premises or other tenants or occupants of the Building or their property; or (d) cause harmful air emissions or any unusual or other objectionable odors, noises or emissions to emanate from the Premises; (iii) in a manner which shall increase such insurance rates on the Building or on property located therein over that applicable when Tenant first took occupancy of the Premises hereunder; or (vii) in violation of any exclusive use granted to any other tenant in the Building. (b) With respect to the provisions set out below. b) Authorised Users may use and occupancy of the Premises and the Common Areas, Tenant will not: : (i) Remove place or alter the author’s name(smaintain any signage (except as may be permitted by Article 10 below), Trash (hereinafter defined) or other articles in any vestibule or entry of the publisher’s copyright notices Premises, on the footwalks or corridors adjacent thereto or elsewhere on the exterior of the Premises, nor obstruct any driveway, corridor, footwalk, parking area, mall or any other Common Areas; (ii) permit undue accumulations of or burn garbage, trash, rubbish or other means refuse (collectively, “Trash”) within or outside of identification the Premises; (iii) permit the parking of vehicles so as to interfere with the use of any driveway, corridor, footwalk, parking area, or other Common Areas; (iv) receive or ship articles of any kind outside of those areas reasonably designated by Landlord; (v) conduct or permit to be conducted any auction, going out of business sale, bankruptcy sale (unless directed by court order), or other similar type sale in or connected with the Premises; (vi) use the name of Landlord, or any and all disclaimers as they appear of Landlord’s affiliates or subsidiaries in any publicity, promotion, press release, advertising, printed, electronic or display materials without Landlord’s prior written consent (which may be withheld in Landlord’s sole discretion); (vii) permit any animals other than service animals in the Licensed Materials; iiBuilding; or (viii) Systematically make print except in connection with Alterations (hereinafter defined) approved by Landlord, cause or electronic copies of multiple extracts permit any hole to be drilled or make multiple copies of made in any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)Building. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. Tenant shall not use or permit the Leased Premises to be used in any manner other than the Permitted Uses. Notwithstanding anything contained herein to the contrary, Tenant shall not use or permit the Leased Premises to be used in any manner which would (a) The Licensee shall be contrary to any statute, rule, order, ordinance, requirement or regulation applicable or Tenant's use reasonable efforts to ensure that the Authorised Users are aware of the prohibitions on the use of the Licensed Materials set out thereof including, but in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not no way limited to the provisions set out below. Environmental Laws, as such term is hereafter defined; (b) Authorised Users may not: icause injury to the Leased Premises; (c) Remove constitute a public or alter private nuisance or waste or constitute or create any noise, vibration or other sound that is not within industry standards for the author’s name(smachinery or equipment causing such noise, vibration or sound; (d) render the insurance on the Leased Premises void or the publisher’s copyright notices insurance risk more hazardous or other means create any defense to payment; (e) require any additional retrofitting or improvements to Leased Premises to fully comply with any applicable laws, rules or regulations of identification any governmental authority or body, including, but in no way limited to, any requirements of the Occupational Safety and all disclaimers as they appear Health Act and the Americans with Disabilities Act; and (f) be inconsistent with the general tone and tenor of the operations of the neighboring buildings, facilities or neighborhood uses in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part general area of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials Leased Premises (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part"Prohibited Use"); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇▇ agrees that it will promptly, upon discovery of any such Prohibited Use, take all necessary steps to compel the discontinuance of such use. Landlord shall be entitled to and shall have the right and authority, as part of the rules and regulations that may be imposed from time to time, to fully or partially restrict, regulate and/or dictate areas of the Leased Premises in which smoking may or may not take place or be permitted including, without limitations, imposing regulations that would prohibit smoking in any confined area.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee Tenant and Tenant’s agents shall not commit or suffer to be committed any waste upon the Premises. Tenant and Tenant’s agents shall not use reasonable efforts or allow the Premises to ensure that be used for any unlawful or hazardous purpose or any purpose not permitted by this Lease, nor shall Tenant or Tenant’s agents cause, maintain, or permit any nuisance in, on or about the Authorised Users are aware Premises. Tenant and Tenant’s agents shall not do or permit anything to be done in or about the Premises nor bring or keep anything in the Premises which will in any way increase the rate of any insurance upon any portion of the prohibitions on Project or any of its contents, or cause a cancellation of any insurance policy covering any portion of the Project or any of its contents, nor shall Tenant or Tenant’s agents keep, use or sell or permit to be kept, used or sold in or about the Premises any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance upon any portion of the Project or any of its contents is increased because of Tenant’s particular use of the Licensed Materials Premises or that of Tenant’s agents, Tenant shall pay, as Additional Rent, the full cost of such increase. The preceding to the contrary notwithstanding, Landlord acknowledges that so long as Tenant uses the Premises for the permitted uses set out forth in this Licence and Paragraph 1.9 above, such uses shall not cause any increase in the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect rate of their access to and use insurance upon any portion of the Licensed MaterialsProject or cause a cancellation of any insurance policy covering any portion of the Project. The Licensee Tenant and Tenant’s agents shall not place any loads upon the floor, walls or ceiling of the Premises which would endanger the Building or the structural elements thereof or of the Premises, nor place any harmful liquids in the drainage system of the Building or Common Area. No waste materials or refuse shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited dumped upon or permitted to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of remain upon any part of the Licensed Materials Project except in enclosed trash containers designated for any that purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)Landlord. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee Tenant and Tenant's agents shall use reasonable efforts not commit or suffer to ensure that be committed any waste upon the Authorised Users are aware Premises. Tenant and Tenant's agents shall not do or permit anything to be done in or about the Premises or Common Area which will in any way obstruct or interfere with the rights of other tenants of the prohibitions on the use Building, other authorized users of the Licensed Materials set out Common Area, or occupants of neighboring property, or injure or annoy them. Tenant and Tenant's agents shall not use or allow the Premises to be used for any unlawful, immoral or hazardous purpose or any purpose not permitted by this Lease nor shall Tenant or Tenant's agents cause, maintain, or permit any nuisance in, on or about the Premises. Tenant and Tenant's agents shall not do or permit anything to be done in this Licence and or about the Licensee Premises nor bring or keep anything in or about the Premises which will in any way increase the existing rate or affect any insurance upon the Premises, Common Area, Land or Building or any part thereof or any of its contents, or cause a cancellation of any insurance policy covering the Premises, Building, Land or Common Area or any part thereof or any of its con- tents, nor shall Tenant or Tenant's agents keep, use reasonable endeavours or sell or permit to ensure that be kept, used or sold in or about the Premises any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance upon the Premises, Building, Land or Common Area or any part thereof or any of its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use contents is increased because of the Licensed Materialsacts or omissions of Tenant or Tenant's agents, Tenant shall pay, as Additional Rent, the full cost of such increase; provided, however, this provision shall in no event be deemed to constitute a waiver of Landlord's right to declare a default hereunder by reason of such increase or of any other rights or remedies of Landlord in connection with such increase. The Licensee Tenant and Tenant's agents shall not place any loads upon the floor, walls or ceiling of the Premises which would endanger the Building or the structural elements thereof or of the Premises, nor place any harmful liquids in the drainage system of the Building or Common Area. No waste materials or refuse shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited dumped upon or permitted to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of remain upon any part of the Licensed Materials Premises, Land, Common Area or Building except in enclosed trash containers designed for that purpose by Landlord. No materials, supplies, equipment, finished products (or semi-finished products), raw materials, or other articles of any purpose other than that nature shall be stored upon, or be permitted by this Licence; iii) Prepare derivative works or downloadto remain on, mount or distribute any part portion of the Licensed Material on any electronic system Land, Common Area or network, including without limitation Building outside the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)Premises. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. a) The Licensee Tenant and Tenant’s agents shall use reasonable efforts not commit or suffer to ensure that be committed any waste upon the Authorised Users are aware Premises. Tenant and Tenant’s agents shall not do or permit anything to be done in or about the Premises or Common Area which will in any way obstruct or interfere with the rights of any authorized users of the prohibitions Common Area, or occupants of neighboring property, or injure or annoy them. Tenant and Tenant’s agents shall not use or allow the Premises to be used for any unlawful, immoral or hazardous purpose (except the foregoing shall not preclude Tenant from using Hazardous Materials in connection with Tenant’s business that are approved by Landlord pursuant to the terms of Paragraph 6.4 below) or any purpose not permitted by this Lease, nor shall Tenant or Tenant’s agents cause, maintain, or permit any nuisance in, on or about the use Premises. Tenant and Tenant’s agents shall not do or permit anything to be done in or about the Premises nor bring or keep anything in the Premises which will in any way increase the rate of any insurance upon any portion of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that Project or any of its Authorised Users do not breach the prohibitions set out in this Licence in respect contents, or cause a cancellation of their access to and use any insurance policy covering any portion of the Licensed MaterialsProject or any of its contents, nor shall Tenant or Tenant’s agents keep, use or sell or permit to be kept, used or sold in or about the Premises any articles which may be prohibited by a standard form policy of fire insurance. The Licensee In the event the rate of any insurance upon any portion of the Project or any of its contents is increased because of the acts or omissions of Tenant or Tenant’s agents, Tenant shall pay, as Additional Rent, the full cost of such increase. Tenant and Tenant’s agents shall not place any loads upon the floor, walls or ceiling of the Premises which would endanger the Building or the structural elements thereof or of the Premises, nor place any harmful liquids in the drainage system of the Building or Common Area. No waste materials or refuse shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited dumped upon or permitted to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of remain upon any part of the Licensed Materials for Project except in properly designed and constructed trash receptacles or discharge systems and in compliance with all applicable Laws pertaining to the disposal of such waste materials or refuse. No materials, supplies, equipment, finished products (or semifinished products), raw materials, or other articles of any purpose other than that nature shall be stored upon, or be permitted by this Licence; iii) Prepare derivative works or downloadto remain on, mount or distribute any part portion of the Licensed Material on any electronic system or network, including without limitation Project outside the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending)Premises. c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any reason.

Prohibited Uses. Tenant shall not use, or suffer or permit the use of, or suffer or permit anything to be done in or anything to be brought into or kept in, the Demised Premises or any part thereof (i) which would violate any of the covenants, agreements, terms, provisions and conditions of this Lease, (ii) for any unlawful purposes or in any unlawful manner, or (iii) which, in the reasonable judgment of Landlord shall in any way (a) The Licensee shall use reasonable efforts impair or tend to ensure that impair the Authorised Users are aware appearance or reputation of the prohibitions on Building, (b) impair or interfere with or tend to impair or interfere with any of the Building services or the proper and economic heating, cleaning, air conditioning or other servicing of the Building or with the use of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users of any of the provisions of this Licence, including but not limited to the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part areas of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyoneBuilding, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior occasion discomfort, inconvenience or annoyance to carrying out or attempting to carry out any of the foregoing usesother tenants or occupants of the Building through the transmission of noise, odors, vibrations, dust, fumes or other emissions perceptible outside the Demised Premises. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5Without limiting the generality of the foregoing, no food shall be prepared or served for consumption by the general public on or about the Demised Premises; no intoxicating liquors or alcoholic beverages shall be sold or otherwise served for consumption by the general public on or about the Demised Premises; no lottery tickets (even where the sale of such tickets is not illegal) shall continue be sold and no gambling, betting or wagering shall otherwise be permitted on or about the Demised Premises; no loitering shall be permitted on or about the Demised Premises; and no loading or unloading of supplies or other material to apply after termination or from the Demised Premises shall be permitted on the Land except at times and in locations to be designated by Landlord. Tenant shall maintain the Demised Premises in a sanitary condition, free of this Licence for any reasonrodents and vermin, and shall suitably store all trash and rubbish in the Demised Premises or other locations designated by Landlord from time to time.