Common use of Prohibited Uses Clause in Contracts

Prohibited Uses. (a) Tenant will not use, occupy or permit the use or occupancy of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.

Prohibited Uses. (a) Tenant will not use, occupy or permit The Licensee shall use reasonable efforts to ensure that the Authorised Users are aware of the prohibitions on the use or occupancy of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation provisions of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premisesthis Licence, including but not limited to zoning, environmental the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and utility conservation matters (hereinafter “Legal Requirements”), (all disclaimers as they appear in the Licensed Materials; ii) covenantsSystematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, conditionsmount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or restrictions applicable to such Premises and appearing of record in the office transmit any part of the county recorder Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirementsinter-library lending). (bc) Tenant shall not keep The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or permit attempting to be kept any substance in, or conduct or permit to be conducted any operation from, carry out any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrationsforegoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant This clause 5) shall not install or permit continue to remain apply after termination of this Licence for any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any wayreason. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.

Prohibited Uses. (a) Tenant will Throughout the Term, Landlord shall not usefurther develop the Property, occupy or permit other than consistent with the use or occupancy provisions of any this Lease, and, without limiting the generality thereof, no such further development shall be permitted if (1) the same would cause a violation of the Premises for any purpose provisions of Section 4.8(b) hereof or Section 14.20 hereof, or (2) the same would otherwise result in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances an increase in the amount of any governmental authority in any way applicable to Additional Rent payable by Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”)hereunder, (ii) covenantsany other cost or expense being imposed upon Tenant or any Tenant Party, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirementsany reduction in the value of the Leased Premises to Tenant or any Tenant Party, (iv) parking or traffic flow on the Property being adversely affected from the perspective of Tenant or any Tenant Party, (v) any reduction in the function or utility of the Common Areas (or any portion thereof) from the perspective of Tenant or any Tenant Party. (b) Tenant Throughout the Term, Landlord shall not keep use, or permit the use of, the Property (or any part thereof) for any Prohibited Uses. The term “Prohibited Uses” shall mean (i) any use that emits an obnoxious odor, noise or sound that can be heard or smelled outside of the premises; (ii) any use in violation of zoning regulations or any other governmental restrictions applicable to the Property; (iii) any use that, by its nature, (even if such use is legally permissible) would result in parking or traffic flow on the Property being materially adversely affected from the perspective of Tenant or any Tenant Party; (iv) any operation primarily used as a warehouse or storage facility, assembling or manufacturing, distilling, refining, rendering, processing, smelting, agricultural or mining operations; (v) any mobile home park or sales, trailer court, labor camp, junk yard or stockyard; (vi) any central laundry, dry cleaning plant or laundromat; provided, however, this prohibition shall not be kept applicable to on-site services oriented only to pickup and delivery by consumers; (vii) any substance inautomobile, truck, trailer or recreational vehicle sales, leasing, display, repair or body shop; (viii) any living quarters, sleeping apartments, hotel or lodging rooms; (xi) veterinary hospitals, animal raising or breeding facilities, animal boarding facilities or pet shops; (x) mortuaries or funeral homes; (xi) any establishment that sells, rents or exhibits pornographic materials; (xii) massage parlors or any form of sexually oriented business (including novelty merchandise sales); (xiii) bars, taverns or brew pubs; (xiv) flea markets, amusement or video arcades, computer game rooms, pool or billiard halls, bingo halls, dance halls, discos or night clubs; (xv) sales of paraphernalia for use with illicit drugs; (xvi) carnivals, amusement parks or circuses; (xvii) pawn shops, auction houses, second hand stores, consignment shops, army/navy surplus stores or gun shops; (xviii) gambling facilities or sports betting parlor; (xix) churches, synagogues or other places of worship; (xx) assembly halls or meeting facilities; (xxi) technical or vocational schools or any other operation primarily engaged in education or training activities; (xxii) medical clinics, abortion clinics, medical laboratories or screening facilities; (xxiii) any agency (public or private) providing health, welfare, social or human services, or conduct (xxiv) tattoo parlors, fortune telling or permit to be conducted spiritual readings; (xxv) facilities that collect donated goods and products; (xxvi) bowling alleys, skating rinks, archery or gun ranges, (xxvii) postal facilities, tax collectors, tag agencies, jails or detention centers, courthouses or any operation fromother form of agency dealing with civil authority. Notwithstanding the foregoing, the term “Prohibited Uses” shall not include any use which is permitted under a third party tenant lease of space in the Building which is in effect as of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.Commencement Date. ________________________________________________________________________________________________________________________

Prohibited Uses. Tenant shall not use, permit the use of, permit anything to be done in or on or anything to be brought into or onto or kept in or on the Premises, the Building, the Property or any part of thereof (i) which would violate any covenant, agreement, term, provision or condition of this Lease, (ii) for any unlawful purpose or in any unlawful manner, or (iii) which, in the reasonable judgment of Landlord shall in any way (a) impair or tend to impair the appearance or reputation of the Building or the Property, (b) impair or interfere with or tend to impair or interfere with any of the Building or Property services or the proper and economic heating, cleaning, air conditioning or other servicing of the Building or the Property or any portion thereof or with the use of the Building or the Property or any portion thereof, or (c) occasion discomfort, inconvenience or annoyance to any other tenant, licensee or other occupant of the Building or the Property or any neighboring property, whether through the transmission of noise or odors or vibrations or otherwise. Without limiting the generality of the foregoing, Tenant will shall not use, permit any vending machines in the Premises or use or occupy or permit the use or occupancy of any occupation of the Premises or any part of the Premises as or for any purpose a restaurant business or in any manner which is for the sale or may befurnishing free of charge of food, directly liquors, frozen desserts, ice cream, beverages, or indirectlyother edible products, in violation for public stenography, or for the conducting of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates aspect of banking business; no food shall be prepared or ordinances of any governmental authority served for consumption on or about the Premises; no intoxicating liquors or alcoholic beverages shall be sold or otherwise permitted in any way applicable to Tenant or about the Premises, including but the Building or elsewhere on the Property; no lottery tickets (even where the sale of such tickets is not limited illegal) shall be sold and no gambling, betting or wagering shall otherwise be permitted in or about the Premises, the Building or elsewhere on the Property; no loitering shall be permitted in or about the Premises, the Building or elsewhere on the Property; and no loading or unloading of supplies or other material to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such from the Premises and appearing of record shall be permitted in the office of Building or elsewhere on the county recorder of the county Property except at times and in which such Premises are located on or before the date on which such Premises became subject locations to this Lease, or (iii) insurance requirements. (b) be designated by Landlord. Tenant shall not keep bring or permit to be kept brought into or keep in or on the Premises, the Building or elsewhere on the Property any oil or any toxic, hazardous, inflammable, combustible or explosive fluids, materials, chemicals or substances, (including without limitation any hazardous substances within the meaning of Chapter 2 IE of the Massachusetts General Laws and any medical waste or any fluid, material, chemical or substance in, or conduct or permit considered to be conducted any operation from, any of biologically hazardous) (except in the Premises which is not reasonably consistent with the Permitted Use for where’ such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit are related to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any Tenant’s use of the Premises, nor bring provided that the same are stored and handled in a proper fashion consistent with applicable legal standards), or keep anything therein whichcause or permit any odors to emanate from or permeate the Premises. The Premises shall be maintained in a sanitary condition, directly or indirectly, would or might cause a cancellation and kept free of any insurance policy covering such rodents and vermin. Tenant shall suitably store all trash and rubbish in the Premises, nor shall Tenant sell the Building or permit elsewhere on the Property in locations designated by Landlord from time to be kept, used time. The language of this Section prohibiting the preparation or sold in serving of food for consumption on or about any the Premises notwithstanding, but subject to the other terms and conditions of the Lease and subject to the other terms and conditions of this Section entitled “Prohibited Uses.”, (including, without limitation, the prohibition against intoxicating liquors and alcoholic beverages), (i) Tenant’s employees and invitees may prepare, serve and consume food and beverages (a) which are brought into the Premises any articles which may by such persons for their own consumption, (b) are in the nature of snacks, coffee or soda and provided by the Tenant or (c) are typically prepared, served and consumed in typical first class office space in Newton and Boston, Massachusetts, provided however that such preparation, serving and consumption shall be prohibited by done in a standard form policy of fire insurance unless manner typical to first class office space in Newton and Boston, Massachusetts, and (ii), Tenant provides additional insurance coverage extending protection to cover all risks associated may, with those articles. (f) Tenant shallLandlord’s prior written consent, install at Tenant’s sole cost and expense, promptly comply one bottled water dispenser (utilizing water bottles with all Legal Requirements now in force or a capacity of not more than five gallons each and dispensing not more than one bottle at a time without manually removing and replacing the one bottle from which may hereafter be in force water is dispensed), coffee maker, microwave and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the refrigerator for use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant. Landlord consents to the installation by Tenant at Tenant’s improvements or actssole expense, of one bottled water dispenser (as described in the immediately preceding sentence), a coffee maker, a microwave and a refrigerator for use by Tenant.

Prohibited Uses. Tenant shall not use the Premises: (ai) Tenant will not use, occupy or permit the use or occupancy of any In violation of the Premises restrictive covenants described in Section 9.10 of that certain Declaration of Protective Covenants and Owners Association for any purpose Cool Springs East Side dated October 4, 1994, of record in Book 1235, page 725, Register’s Office for ▇▇▇▇▇▇▇▇▇▇ County, Tennessee (the “Protective Covenants”), a copy of which has been provided by Landlord to Tenant, or in any manner which is or may be, directly or indirectly, in violation of the rules and regulations described in Section 12b hereof; (ii) In any (i) judicial decisionsmanner that constitutes a nuisance or trespass, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority will in any way applicable to Tenant violate any law, statute, ordinance or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, governmental rule or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements regulation now in force or which may hereafter be in force and enacted or promulgated, (iii) In any manner that will adversely affect or interfere with any services required to be furnished by Landlord to Tenant, or to any other tenants or occupants of the Building or with the requirements proper and economical rendition of any board such service. (iv) In any manner that will in any way obstruct or interfere with the rights of fire underwriters other tenants of the Building or injure them, or use or allow the Premises to be used for any unlawful purpose, or commit or suffer to be committed any waste in, on or about the Premises; (v) In any manner which increases any insurance premiums, or makes such insurance unavailable to Landlord on the Building; provided that, in the event of an increase in Landlord’s insurance premiums which results from Tenant’s use of the Premises, Landlord may elect to permit the use and charge Tenant for the increase in premiums, and Tenant’s failure to pay Landlord, on demand, the amount of such increase shall be an event of default (in any action or proceeding wherein Landlord and Tenant are parties, a schedule or “make up” of rates applicable to the Building issued by the Tennessee Insurance Bureau, or other similar body now fixing such fire insurance rates, shall be conclusive evidence of the facts therein stated and the several items and charges in the fire insurance rates therein); (vi) In any manner that creates unusual demands for electricity, heating or hereafter constituted relating air conditioning (except as permitted by Section 4(c) below); or (vii) For any purpose except the Permitted Use, unless consented to by Landlord in writing. (viii) That shall cause or affecting permit the use, generation, storage or disposal in or about the Premises or the Building of any substances, materials or wastes subject to regulation under Federal, State or local laws from time to time in effect concerning hazardous, toxic or radioactive materials (excluding the storage and use or occupancy of normal cleaning supplies and office supplies customarily used for the Permitted Use, all of the Premiseswhich shall be permitted without Landlord’s consent so long as such items are stored and used in compliance with applicable environmental laws), excluding such structural changes as do not relate to unless Tenant shall have received Landlord’s prior written consent, which Landlord may withhold or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or actsat any time revoke in its sole discretion.

Prohibited Uses. (a) Tenant will The Premises shall not use, occupy be used for any use which conflicts with any existing declaration of restrictions or permit the use covenants or occupancy of any of other agreement recorded against or binding upon the Premises for or any purpose existing mortgage or in any manner which is or may bedeed of trust In addition, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but shall not limited be used for any use other than the use permitted by Section 9 including,- without limitation, any use- which conflicts with or otherwise violates any exclusive uses granted by Landlord to zoningother tenants, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located as set forth on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Exhibit "D". Tenant shall not keep do or permit anything to be kept any substance in, done in or conduct or permit to be conducted any operation from, any of about the Premises which is not reasonably consistent will obstruct or interfere with the Permitted Use for such Premises and which might emit offensive odors rights of other tenants or conditionsoccupants of the Shopping Center, or make undue noise injure or create undue vibrations. (c) Tenant shall not commit annoy them or permit to remain any waste to any of the Premises. (d) Tenant shall not install use or permit to remain any improvements to any of allow the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed used for any action improper, immoral, unlawful or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premisesobjectionable purpose, nor shall Tenant sell cause, maintain or permit any nuisance in, on or about the Premises. Tenant shall not install, maintain or use an underground storage tank. Tenant shall not do or permit anything to be kept, used done which will invalidate or sold in or about any of increase the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters fire, extended coverage or any other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of insurance policy covering the Premises, excluding the Shopping Center and/or property located therein. Tenant shall promptly pay or reimburse Landlord, as additional rent, the full amount of any additional premium charged Landlord for any insurance policy by reason of Tenant's failure to comply with this Section and/or the Section entitled "Compliance with Law"; provided, mat except in the case of a use by Tenant that is expressly permitted by the terms of this Lease, such structural changes as do reimbursement shall not relate be Landlord's exclusive remedy, nor shall it limit or compromise any other rights granted Landlord by this Lease or by law or equity. Nothing contained in this Section 10 shall be construed or deemed in any way to or affect increase the scope of Tenant's use or occupancy set forth in Section 9 of the Premises, or as are not related to or afforded by Tenant’s improvements or actsthis Lease.

Prohibited Uses. (a) Tenant will further covenants and agrees that Tenant shall not use, occupy or knowingly suffer or permit any person or persons to use, the Premises or any part thereof for any use or occupancy of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of Applicable Laws including, without limitation, any such Applicable Laws relating to Hazardous Materials, or any Underlying Documents. Landlord shall have the right to impose reasonable, nondiscriminatory and customary rule and regulations regarding the use of the Project that do not unreasonably interfere with Tenant’s use of the Premises, as reasonably deemed necessary by Landlord with respect to the orderly operation of the Project (“Rules and Regulations”), and Tenant shall comply with such reasonable rules and regulations; provided that (i) judicial decisionsLandlord shall not enforce, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates change or ordinances of any governmental authority modify such rules and regulations in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”)a discriminatory manner, (ii) such rules and regulations shall do not unreasonably interfere with the normal and customary conduct of Tenant’s business, (iii) any such rules and regulations shall not materially increase Tenant’s obligations hereunder, materially decrease Tenant’s rights hereunder, or materially decrease Landlord’s obligations hereunder, and (iv) Landlord shall provide Tenant with at least thirty (30) days’ prior written notice of any such rules and regulations. Tenant shall not do or permit anything to be done in or about the Premises which will in any way obstruct or interfere with the rights of other tenants or occupants of the Building, or injure or annoy them or use or allow the Premises to be used for any improper, unlawful or objectionable purpose, nor shall Tenant cause, maintain or permit any nuisance in, on or about the Premises. Tenant shall comply with, and ▇▇▇▇▇▇’s rights and obligations under the Lease and ▇▇▇▇▇▇’s use of the Premises shall be subject and subordinate to, all recorded easements, covenants, conditions, and restrictions now or restrictions applicable to such Premises and appearing of record in hereafter affecting the office of Project, so long as the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall same do not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any unreasonably interfere with ▇▇▇▇▇▇’s use of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, parking rights or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at materially increase Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force obligations or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by decrease Tenant’s improvements or actsrights under this Lease.

Prohibited Uses. (a) Tenant will shall not use, occupy use the Premises or permit anything to be done in or about the use Premises nor keep or occupancy of bring anything in the Premises that will in any way conflict with any of the Premises for any purpose requirements of the Board of Fire Underwriters or similar body now or hereafter constituted or in any manner which is way increase the existing rate of or may be, directly affect any policy of fire or indirectly, in violation other insurance upon the Buildings or any of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditionstheir contents, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering (unless Tenant pays such Premisesrate increase). No auctions may be held or otherwise conducted in, on or about the Premises or anywhere else in the Property without Landlord’s prior written consent, which Landlord may withhold in its sole discretion. Tenant shall not do, and shall not permit any other Tenant Party to do, anything in the Property that will in any way obstruct or interfere with the rights of Landlord, other tenants or occupants of the Property, or other persons or businesses in the area, or injure or unreasonably annoy other tenants or use or allow the Premises to be used for any unlawful purpose, as determined by Landlord, in its reasonable discretion, for the benefit, quiet enjoyment and use by Landlord and all other tenants or occupants of the Buildings; nor shall Tenant sell cause, maintain or permit any private or public nuisance in, on or about the Premises or any other part of the Property, including, but not limited to, any offensive odors, noises, fumes or vibrations. Tenant shall not damage or deface or otherwise commit or suffer to be keptcommitted any waste in, used or sold in upon or about the Premises. Tenant shall not place or store, nor permit any other person or entity to place or store, any property, equipment, materials, supplies, personal property or any other items or goods outside of the Premises other than in compliance with all applicable Laws. Tenant shall place no loads upon the floors, walls, or ceilings in excess of the maximum designed load permitted by the applicable Uniform Building Code or that may damage the Premises or outside areas; nor place any articles which may be prohibited by a standard form policy of fire insurance unless harmful liquids in the drainage systems; nor dump or store waste materials, refuse or other such materials, or allow such to remain outside the Premises, except in refuse dumpsters, storage tanks or in any enclosed trash areas provided. Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly shall comply with all Legal Requirements now in force or which may hereafter be in force applicable Laws, Recorded Matters, and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating Rules and Regulations applicable to or affecting the its use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy any other areas of the PremisesProperty Landlord reserves for Tenant’s exclusive use, and/or the Common Area. If Tenant fails to so comply with such Laws, Recorded Matters, Rules and Regulations, or as are the provisions of this Lease, Landlord shall have rights and remedies of Landlord under this Lease including, but not related limited to, the payment by Tenant to or afforded by Landlord of all Enforcement Expenses and Landlord’s costs and expenses, if any, to cure any of such failures of Tenant’s improvements or acts, if Landlord, at its sole option, elects to undertake such cure.

Prohibited Uses. (a) Tenant will shall not useuse the Premises or allow the Premises to be used for any illegal or immoral purpose, occupy or permit so as to create waste, or constitute a private or public nuisance. Tenant shall not place any loads upon the floors, wails, or ceiling that endanger the structure, or overload existing electrical or other mechanical systems. Tenant shall not use any machinery or occupancy of equipment which causes any substantial noise or vibration. No waste materials or refuse shall be dumped upon or permitted to remain upon any part of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any outside of the Premises which is not reasonably consistent with the Permitted Use except in trash containers placed inside exterior enclosures designated by Landlord for such Premises and which might emit offensive odors that purpose or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any inside of the Premises which exceed the structural loads of floors where approved by Landlord, No materials, supplies, equipment, finished products or walls semi-finished products, raw materials or articles of any buildings located nature shall be stored upon or permitted to remain outside the Premises or on such Premisesany portion of the Common Area unless otherwise approved by Landlord in its sole discretion. No loudspeaker or other device, system or adversely affect apparatus which can be heard outside the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant Premises shall not commit or permit to be committed any action or circumstance used in or about any at the Premises without the prior written consent of Landlord. No explosives or firearms shall be brought into the Premises. Landlord shall have the right to enter and conduct an inspection of the Premises, nor bring or keep anything therein whichat any reasonable time and upon reasonable advance notice (of not less than 24 hours, directly or indirectlyexcept in the case of an emergency in which event no prior notice shall be required, would or might cause a cancellation but Landlord shall give Tenant prompt notice following such emergency entry), to determine whether Tenant is complying with the terms of this Section 6.2. In the event such inspection identifies any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold deficiencies in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and compliance with the requirements terms of this Section 6.2, Tenant shall promptly correct such deficiency and shall reimburse Landlord within thirty (30) days after written demand as Additional Rent for any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding costs incurred by Landlord in connection with such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or actsinspection.

Prohibited Uses. (a) Tenant will not useThe uses prohibited under this Lease shall include, occupy or permit the without limitation, use or occupancy of any of the Premises or a portion thereof for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances offices of any agency or bureau of the United States or any state or political subdivision thereof; (ii) offices or agencies of any foreign governmental authority or political subdivision thereof; (iii) offices of any health care professionals or service organization; (iv) schools or other training facilities which are not ancillary to corporate, executive or professional office use; (v) retail or restaurant uses; or (vi) communications firms such as radio and/or television stations. Tenant shall not allow occupancy density of use of the Premises which is greater than eight (8) persons per 1,000 rentable square feet of space located in any way applicable to Tenant or the Premises. Notwithstanding the foregoing, including but not limited subject to zoningthe following terms, environmental and utility conservation matters Tenant shall be permitted to allow occupancy density of use of the Premises which is greater than such foregoing ratio, provided that (hereinafter “Legal Requirements”)i) Tenant shall provide Landlord with reasonable advance notice of such anticipated increased occupancy density, (ii) in no event shall Tenant allow occupancy density of use of the Premises which is greater than the density permitted by Applicable Laws for general office use tenants in the Building and Comparable Buildings, and (iii) Tenant shall be solely responsible (including all costs and expenses relating thereto) for any required modifications, upgrades or other equipment or devices to appropriately support such increased occupancy density in accordance with Section 6.2, below, and any such modifications or other work or installations shall otherwise be subject to the terms of Article 8 of this Lease. Tenant further covenants and agrees that Tenant shall not use, or suffer or permit any person or persons to use, the Premises or any part thereof for any use or purpose contrary to the provisions of the Rules and Regulations set forth in Exhibit D, attached hereto, or in violation of the laws of the United States of America, the State of California, or the ordinances, regulations or requirements of the local municipal or county governing body or other lawful authorities having jurisdiction over the Project) including, without limitation, any such laws, ordinances, regulations or requirements relating to hazardous materials or substances, as those terms are defined by applicable laws now or hereafter in effect; provided, however, Landlord shall not enforce, change or modify the Rules and Regulations in a discriminatory manner and Landlord agrees that the Rules and Regulations shall not be unreasonably modified or enforced in a manner which will unreasonably interfere with the normal and customary conduct of Tenant’s business. Tenant shall not do or permit anything to be done in or about the Premises which will in any way damage the reputation of the Project or obstruct or interfere with the rights of other tenants or occupants of the Building, or injure or annoy them or use or allow the Premises to be used for any improper, unlawful or objectionable purpose, nor shall Tenant cause, maintain or permit any nuisance in, on or about the Premises. As of the date of this Lease, Landlord hereby represents that there are no existing recorded easements, covenants, conditions, or restrictions applicable affecting the Project with which Tenant is required to such Premises and appearing of record in comply. Notwithstanding the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Leaseforegoing, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance incomply with, or conduct or permit to be conducted any operation from, any and Tenant’s rights and obligations under the Lease and Tenant’s use of the Premises which is shall be subject and subordinate to, all recorded easements, covenants, conditions, and restrictions (collectively, the “CC&Rs”) hereafter affecting the Project, provided that Landlord shall not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or enter into any recorded easements, covenants, conditions, or make undue noise restrictions affecting the Project after the date of this Lease which prevents Tenant from using, or create undue vibrations. (c) Tenant shall not commit unreasonably interferes with Tenant’s use of or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of access to, the Premises which exceed for the structural loads of floors or walls of any buildings located on such PremisesPermitted Use, or otherwise materially adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at affects Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or actsrights under this Lease.

Prohibited Uses. (a) Notwithstanding any other provision of this Lease, Tenant will shall not useuse the Premises or the Building, occupy or any part thereof, or suffer or permit the use or occupancy of the Premises or the Building or any part thereof by Tenant, its Portfolio Companies, and/or their agents, servants, employees, consultants, contractors, subcontractors, licensees and/or subtenants (collectively with Tenant, the “Tenant Parties”) (i) in a manner which would violate any of the covenants, agreements, terms, provisions and conditions of this Lease or otherwise applicable to or binding upon the Premises; (ii) for any unlawful purposes or in any unlawful manner; (iii) which, in the reasonable judgment of Landlord (taking into account the use of the Building as a combination office and retail building and the Permitted Uses) shall (a) impair the appearance or reputation of the Building; (b) impair, interfere with or otherwise diminish the quality of any of the Building services or the proper and economic heating, cleaning, ventilating, air conditioning or other servicing of the Building or Premises, or the use or occupancy of any of the Premises for any purpose Common Areas; (c) occasion discomfort, inconvenience or annoyance in any material respect, or cause any injury or damage to any occupants of the Premises or other tenants or occupants of the Building or their property; or (d) cause harmful air emissions or any unusual or other objectionable odors, noises or emissions to emanate from the Premises; (iv) in a manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or inconsistent with the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office operation and/or maintenance of the county recorder Building as a first-class combination office and retail facility; (v) for any fermentation processes whatsoever; or (vi) in a manner which shall increase such insurance rates on the Building or on property located therein over that applicable when Tenant first took occupancy of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirementshereunder. (b) With respect to the use and occupancy of the Premises and the Common Areas, Tenant shall not keep will not: (i) place or maintain any signage (except as permitted by Section 12 below), trash, refuse or other articles in any vestibule or entry of the Premises, on the footwalks or corridors adjacent thereto or elsewhere on the exterior of the Premises, nor obstruct any driveway, corridor, footwalk, parking area, mall or any other Common Areas; (ii) permit undue accumulations of or burn garbage, trash, rubbish or other refuse within or without the Premises; (iii) permit the parking of vehicles so as to be kept interfere with the use of any substance indriveway, corridor, footwalk, parking area, or other Common Areas; (iv) receive or ship articles of any kind outside of those areas reasonably designated by Landlord; (v) conduct or permit to be conducted any operation fromauction, any going out of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditionsbusiness sale, or make undue noise or create undue vibrations. bankruptcy sale (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premisesunless directed by court order), or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now type sale in or hereafter constituted relating to or affecting connected with the Premises; (vi) use or occupancy of all the name of the PremisesBuilding, excluding such structural changes as do not relate to the Property, Landlord, or affect the use any of Landlord’s affiliates or occupancy subsidiaries or any photograph, film, drawing, or other depiction or representation of the PremisesBuilding and/or the Property or any part thereof, which contains signage or distinctive architectural characteristics that cause the scene photographed, filmed, drawn, depicted, or represented to be identifiable as are not related to being the Building and/or the Property, in any publicity, promotion, trailer, press release, advertising, printed, or afforded by display materials without Landlord’s prior written consent; or (vii) except in connection with Tenant’s improvements Work and/or Alterations (hereinafter defined) approved by Landlord, cause or actspermit any hole to be drilled or made in any part of the Building.

Prohibited Uses. (a) In no event shall Tenant will not use, occupy use any part of the Premises for any retail sales activity or permit the use or occupancy of for any of the following noxious uses: (i) a second hand or surplus store; (ii) a mobile home park or trailer court; (iii) a fire, bankruptcy or auction sale; (iv) a laundry or dry cleaning operation; (v) automobile, truck, R.V. sales, leasing, display or repair; (vi) mortuary; (vii) any center for medical procedures, counseling or activities related to abortion, birth control or euthanasia; (viii) any establishment selling or exhibiting pornographic materials; (ix) an auto parts store or gas station; (x) any church, synagogue, mosque, temple or other place of worship; (xi) a “head” shop or any establishment displaying or selling drug paraphernalia; (xii) a massage parlor, topless bar or club or restaurant which provides striptease entertainment; (xiii) a landfill, garbage dump or for the dumping, disposal, incineration or storage of garbage or any business storing or handling hazardous materials except in the course of a Permitted Use; (xiv) any carnival or amusement park; (xv) a temporary placement service; (xvi) a drug or alcohol recovery or treatment facility; (xvii) a school or trade school; or (xviii) an off track betting facility or betting club or any other type of gambling establishment. Tenant shall not do or permit anything to be done in or about the Premises that will in any way cause a nuisance, obstruct or interfere with the rights of neighbors or injure or annoy them. Tenant shall not use the Premises, nor allow the Premises to be used, for any purpose or in any manner which is that would invalidate any policy of insurance now or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant hereafter carried on the Building or the Premises. Landlord may promulgate and modify from time to time rules and regulations for the safety, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, care or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any cleanliness of the Premises which is not reasonably consistent shall be complied with the Permitted Use for such Premises by Tenant and which might emit offensive odors or conditionsits employees, or make undue noise or create undue vibrationsagents, visitors and invitees. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.

Prohibited Uses. (a) Notwithstanding any other provision of this Lease, Tenant will shall not useuse the Premises or the Building, occupy or any part thereof, or suffer or permit the use or occupancy of the Premises or the Building or any part thereof by any of the Premises Tenant Parties (i) in a manner which violates any of the covenants, agreements, terms, provisions and conditions of this Lease; (ii) for any purpose unlawful purposes or in any unlawful manner; (iii) which, in the reasonable good faith judgment of Landlord (taking into account the use of the Building as a combination laboratory, research and development and office building and the Permitted Uses) shall (a) impair the appearance or reputation of the Building; (b) impair, interfere with or otherwise diminish the quality of any of the Building services, or the use of any of the Common Areas; (c) occasion discomfort, inconvenience or annoyance in any material respect, or cause any injury or damage to any other tenants or occupants of the Building or their property; or (d) cause harmful air emissions, laboratory odors or noises or any unusual or other objectionable odors, noises or emissions to emanate from the Premises taking into account the use of the Building as a combination laboratory, research and development and office building and the Permitted Uses); (iv) in a manner which is materially inconsistent with the operation and/or maintenance of the Building as a first-class combination office, research, development and laboratory facility; (v) [intentionally omitted]; or may be(vi) in a manner which shall increase such insurance rates on the Building or on property located therein over that applicable when Tenant first took occupancy of the Premises hereunder unless Tenant pays such increase within thirty (30) days after demand therefor from time to time. From and after the Execution Date, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority Landlord shall include substantially similar provisions in any way applicable to Tenant or other leases at the Premises, including but Building and shall not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to enforce such Premises and appearing of record provisions in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirementsa discriminatory manner. (b) With respect to the use and occupancy of the Premises and the Common Areas, Tenant shall not keep will not: (i) place or maintain any signage (except as set forth in Section 12.2 below), trash, refuse or other articles in any vestibule or entry of the Premises, on the footwalks or corridors adjacent thereto or elsewhere on the exterior of the Premises, nor obstruct any driveway, corridor, footwalk, parking area, mall or any other Common Areas; (ii) permit undue accumulations of or burn garbage, trash, rubbish or other refuse within or without the Premises; (iii) permit the parking of vehicles so as to be kept interfere with the use of any substance indriveway, corridor, footwalk, parking area, or other Common Areas; (iv) receive or ship articles of any kind outside of those areas reasonably designated by Landlord; (v) conduct or permit to be conducted any operation fromauction, any going out of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditionsbusiness sale, or make undue noise or create undue vibrations. bankruptcy sale (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premisesunless directed by court order), or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now type sale in or hereafter constituted relating connected with the Premises; (vi) use the name of Landlord, or any of Landlord’s affiliates in any publicity, promotion, trailer, press release, advertising, printed, or display materials without Landlord’s prior written consent, which shall not be unreasonably withheld, conditioned or delayed; or (vii) except in connection with Alterations (hereinafter defined) approved by Landlord or otherwise not requiring Landlord’s approval, cause or permit any hole to be drilled or affecting the use or occupancy of all made in any part of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or actsBuilding.

Prohibited Uses. Tenant shall not use the Premises or allow the Premises to be used for any illegal purpose, or so as to create waste, or constitute a private or public nuisance. Tenant shall use reasonable efforts to maintain cooperative relations with Landlord and the occupants of neighboring buildings in the vicinity of the Property. Such cooperation shall include, as reasonably requested by Landlord (a) responding to complaints regarding operational issues (i.e., lighting, parking, noise, etc.), (b) designating a representative to handle any issues that may arise, and (c) advising Tenant’s employees regarding issues of concern to Tenant’s neighbors. Tenant will shall not useplace any loads upon the floors, occupy walls, or permit ceiling that endanger the structure, or overload existing electrical or other mechanical systems. Tenant shall not use any machinery or occupancy of equipment which causes any substantial noise or vibration. Tenant shall not engage in any action or inaction that (i) jeopardizes the Building’s LEED or Energy Star ratings, or (ii) compromises Landlord’s sustainability goals for the Building as communicated in writing to Tenant. No waste materials or refuse shall be dumped upon or permitted to remain upon any part of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any outside of the Premises which is not reasonably consistent with the Permitted Use except in trash containers placed inside exterior enclosures designated by Landlord for such Premises and which might emit offensive odors that purpose or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any inside of the Premises which exceed the structural loads of floors where approved by Landlord. No materials, supplies, equipment, finished products or walls semi-finished products, raw materials or articles of any buildings located nature shall be stored upon or permitted to remain outside the Premises or on such Premisesany portion of the Common Area unless otherwise approved by Landlord in its reasonable discretion. No loudspeaker or other device, system or adversely affect apparatus which can be heard outside the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant Premises shall not commit or permit to be committed any action or circumstance used in or about any at the Premises without the prior written consent of Landlord. No explosives or firearms shall be brought into the Premises. Landlord shall have the right to enter and conduct an inspection of the Premises, nor bring or keep anything therein whichat any reasonable time and upon reasonable advance notice, directly or indirectly, would or might cause a cancellation to determine whether Tenant is complying with the terms of this Section 7.2. In the event such inspection identifies any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold deficiencies in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and compliance with the requirements terms of this Section 7.2, Tenant shall promptly correct such deficiency and shall reimburse Landlord within ten (10) days after written demand as Additional Rent for any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding reasonable third-party costs incurred by Landlord in connection with such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or actsinspection.

Prohibited Uses. (a) Tenant will not use, occupy or permit the use or occupancy of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant Tenant's agents shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit suffer to be committed any action waste upon the Premises. Tenant and Tenant's agents shall not do or circumstance permit anything to be done in or about the Premises or Common Area which will in any way obstruct or interfere with the rights of any authorized users of the Common Area, or injure or annoy them. Tenant shall not conduct or permit any auction or sale open to the public to be held or conducted on or about the Premises or Common Area. Tenant and Tenant's agents shall not use or allow the Premises to be used for any unlawful or hazardous purpose or any purpose not permitted by this Lease, nor shall Tenant or Tenant's agents cause, maintain, or permit any nuisance in, on or about the Premises, . Tenant and Tenant's agents shall not do or permit anything to be done in or about the Premises or Common Area nor bring or keep anything therein whichin the Premises or Common Area which will in any way increase the rate of any insurance upon the Premises or Common Area or any part thereof or any of its contents, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premisesthe Premises or Common Area or any part thereof or any of its contents, nor shall Tenant or Tenant's agents keep, use or sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance unless upon the Premises or Common Area or any part thereof or any of its contents is increased because of the acts or omissions of Tenant provides additional insurance coverage extending protection or Tenant's agents, Tenant shall pay, as Additional Rent, the full cost of such increase to cover all risks associated the extent attributable solely to Tenant's or its agents' acts or omissions; provided however this provision shall in no event be deemed to constitute a waiver of Landlord's rights or remedies in connection with those articles. such increase. Tenant and Tenant's agents shall not place any loads upon the floor, walls or ceiling of the Premises which would endanger the Premises or the structural elements thereof, nor place any harmful liquids in the drainage system of the Premises. No waste materials or refuse shall be dumped upon or permitted to remain upon any part of the Premises or Common Area except in enclosed trash containers. No materials, supplies, equipment, finished products (f) or semi-finished products), raw materials, or other articles of any nature shall be stored upon, or be permitted to remain on, any portion of the Common Area. Tenant shallshall not allow any activity which in the reasonable opinion of Landlord is detrimental to the operation of the Common Area or to tenants of Landlord in other buildings located on the Common Area or upon real property owned by Landlord adjacent to the Common Area, including but not limited to any picketing, work stoppage, or other concerted activity. Landlord shall have the right to require Tenant, at Tenant’s sole cost 's own expense and expensewithin a reasonable period of time, promptly comply with all Legal Requirements now in force to use Tenant's commercially reasonable efforts to terminate or which may hereafter be in force and control any such picketing, work stoppage or other concerted activity to the extent necessary to eliminate any interference with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all operation of the Premises, excluding Common Area or such structural changes as tenants. Failure by Tenant to use its commercially reasonable efforts to do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded so shall be a Default by Tenant’s improvements . Nothing contained in this paragraph shall be construed as placing Landlord in an employer-employee relationship with any of Tenant's employees or actswith any other employees who may be involved in such activity.

Prohibited Uses. (a) Tenant will shall not use, occupy or suffer or permit the use of, or occupancy of suffer or permit anything to be done in or anything to be brought into or kept in, the Demised Premises or any part thereof (i) which would violate any of the Premises for any purpose or in any manner which is or may becovenants, directly or indirectlyagreements, in violation terms, provisions and conditions of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”)this Lease, (ii) covenants, conditions, for any unlawful purposes or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Leaseany unlawful manner, or (iii) insurance requirements. which, in the reasonable judgment of Landlord shall in any way (a) impair or tend to impair the appearance or reputation of the Building, (b) Tenant shall not keep impair or permit interfere with or tend to be kept any substance in, impair or conduct or permit to be conducted any operation from, interfere with any of the Premises which is not reasonably consistent Building services or the proper and economic heating, cleaning, air conditioning or other servicing of the Building or with the Permitted Use for such Premises and which might emit offensive odors or conditionsuse of any of the other areas of the Building, or make undue noise or create undue vibrations. (c) Tenant shall not commit occasion discomfort, inconvenience or permit to remain any waste annoyance to any of the Premises. (d) Tenant shall not install other tenants or permit to remain any improvements to any occupants of the Building, whether through the transmission of noise or odors or otherwise. Without limiting the generality of the foregoing, no food shall be prepared or served for consumption by the general public on or about the Demised Premises; no intoxicating liquors or alcoholic beverages shall be sold or otherwise served for consumption by the general public on or about the Demised Premises; no lottery tickets (even where the sale of such tickets is not illegal) shall be sold and no gambling, betting or wagering shall otherwise be permitted on or about the Demised Premises; no machinery shall be operated in the Demised Premises which exceed the structural loads of floors or walls if such operation involves vibratory motion of any buildings located kind perceptible outside the Demised Premises; no loitering shall be permitted on such or about the Demised Premises, ; and no loading or adversely affect unloading of supplies or other material to or from the mechanical, plumbing or electrical systems of any such buildings, or affect Demised Premises shall be permitted on the structural integrity of any such buildings Land except at times and in any way. (e) Tenant shall not commit or permit locations to be committed any action or circumstance designated by Landlord. The Demised Premises shall be maintained in or about any a sanitary condition, and kept free of rodents and vermin. All trash and rubbish shall be suitably stored in the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Demised Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating locations designated by Landlord from time to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or actstime.

Prohibited Uses. (a) Notwithstanding any other provision of this Lease, Tenant will shall not useuse the Premises or the Building, occupy or any part thereof, or suffer or permit the use or occupancy of the Premises or the Building or any part thereof by any of the Tenant Parties (i) in a manner which would violate any of the covenants, agreements, terms, provisions and conditions of this Lease or otherwise applicable to or binding upon the Premises; (ii) for any unlawful purposes or in any unlawful manner; (iii) which, in the reasonable judgment of Landlord (taking into account the use of the Building as a combination retail and residential building and the Permitted Uses) shall (a) impair the appearance or reputation of the Building; (b) impair, interfere with or otherwise diminish the quality of any of the Building services or the proper and economic heating, cleaning, ventilating, air conditioning or other servicing of the Building or Premises, or the use or occupancy of any of the Premises for any purpose Common Areas; (c) occasion discomfort, inconvenience or annoyance in any material respect (and Tenant shall not install or use any electrical or other equipment of any kind, which, in the reasonable judgment of Landlord, will cause any such impairment, interference, discomfort, inconvenience, annoyance or injury), or cause any injury or damage to any occupants of the Premises or other tenants or occupants of the Building or their property; or (d) cause harmful air emissions or any unusual or other objectionable odors, noises or emissions to emanate from the Premises; (iv) in a manner which is or may beinconsistent with the operation of the Building as a combination retail and residential facility of the first class in the quality of its maintenance, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditionsuse, or restrictions occupancy; or (v) in a manner which shall increase such insurance rates on the Building or on property located therein over that applicable to such Premises and appearing of record in the office when Tenant first took occupancy of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirementshereunder. (b) With respect to the use and occupancy of the Premises and the Common Areas, Tenant shall not keep will not: (i) place or maintain any signage, trash, refuse or other articles in any vestibule or entry of the Premises, on the footwalks or corridors adjacent thereto or elsewhere on the exterior of the Premises, nor obstruct any driveway, corridor, footwalk, parking area, mall or any other Common Areas; (ii) permit undue accumulations of or burn garbage, trash, rubbish or other refuse within or without the Premises; (iii) permit the parking of vehicles so as to be kept interfere with the use of any substance indriveway, corridor, footwalk, parking area, or other Common Areas; (iv) receive or ship articles of any kind outside of those areas reasonably designated by Landlord; (v) conduct or permit to be conducted any operation fromauction, going out of business sale, bankruptcy sale (unless directed by court order), or other similar type sale in or connected with the Premises; (vi) use the name of the Building, Landlord, or any of Landlord's affiliates or subsidiaries or any photograph, film, drawing, or other depiction or representation of the Premises Building or any part thereof, which contains signage or distinctive architectural characteristics that cause the scene photographed, filmed, drawn, depicted, or represented to be identifiable as being the Building, in any publicity, promotion, trailer, press release, advertising, printed, or display materials without Landlord's prior written consent; (vii) except in connection with Tenant's Work and/or Alterations (hereinafter defined) approved by Landlord, cause or permit any hole to be drilled or made in any part of the Building; (viii) use or permit the use of any objectionable advertising medium such as, without limitation, loudspeakers, phonographs, public address systems, sound amplifiers, reception of radio or television broadcasts within the Building, which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors in any manner audible or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any visible outside of the Premises. ; (dix) Tenant shall not install distribute handbills or permit other advertising matter in any Common Areas; or (x) use the lobbies, corridors or any other Common Areas adjacent to remain any improvements to any of the Premises which exceed for the structural loads of floors sale or walls display of any buildings located on such Premisesmerchandise or for any other business, occupation or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any wayundertaking. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.

Prohibited Uses. (a) Tenant will shall not use, occupy use or permit the Leased Premises to be used in any manner other than the Permitted Uses. Notwithstanding anything contained herein to the contrary, Tenant shall not use or occupancy of any of permit the Leased Premises for any purpose or to be used in any manner which is or may bewould (a) be contrary to any statute, directly or indirectly, in violation of any (i) judicial decisionsrule, order, injunctionsordinance, writsrequirement or regulation applicable or Tenant's use thereof including, statutesbut in no way limited to the Environmental Laws, rulingsas such term is hereafter defined; (b) cause injury to the Leased Premises; (c) constitute a public or private nuisance or waste or constitute or create any noise, rulesvibration or other sound that is not within industry standards for the machinery or equipment causing such noise, regulationsvibration or sound; (d) render the insurance on the Leased Premises void or the insurance risk more hazardous or create any defense to payment; (e) require any additional retrofitting or improvements to Leased Premises to fully comply with any applicable laws, promulgations, directives, permits, certificates rules or ordinances regulations of any governmental authority or body, including, but in no way limited to, any way applicable to Tenant requirements of the Occupational Safety and Health Act and the Americans with Disabilities Act; and (f) be inconsistent with the general tone and tenor of the operations of the neighboring buildings, facilities or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record neighborhood uses in the office general area of the county recorder of the county in which such Leased Premises are located on or before the date on which such Premises became subject to this Lease("Prohibited Use"). ▇▇▇▇▇▇ agrees that it will promptly, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems upon discovery of any such buildingsProhibited Use, take all necessary steps to compel the discontinuance of such use. Landlord shall be entitled to and shall have the right and authority, as part of the rules and regulations that may be imposed from time to time, to fully or affect partially restrict, regulate and/or dictate areas of the structural integrity of any such buildings Leased Premises in which smoking may or may not take place or be permitted including, without limitations, imposing regulations that would prohibit smoking in any wayconfined area. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.

Prohibited Uses. (a) Tenant will not use, occupy or permit the use or occupancy of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant Tenant’s agents shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit suffer to be committed any action waste upon the Premises. Tenant and Tenant’s agents shall not use or circumstance allow the Premises to be used for any unlawful or hazardous purpose or any purpose not permitted by this Lease, nor shall Tenant or Tenant’s agents cause, maintain, or permit any nuisance in, on or about the Premises. Tenant and Tenant’s agents shall not do or permit anything to be done in or about any of the Premises, Premises nor bring or keep anything therein whichin the Premises which will in any way increase the rate of any insurance upon any portion of the Project or any of its contents, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premisesany portion of the Project or any of its contents, nor shall Tenant or Tenant’s agents keep, use or sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at upon any portion of the Project or any of its contents is increased because of Tenant’s sole particular use of the Premises or that of Tenant’s agents, Tenant shall pay, as Additional Rent, the full cost and expenseof such increase. The preceding to the contrary notwithstanding, promptly comply with all Legal Requirements now Landlord acknowledges that so long as Tenant uses the Premises for the permitted uses set forth in force Paragraph 1.9 above, such uses shall not cause any increase in the rate of insurance upon any portion of the Project or which may hereafter be in force and with the requirements cause a cancellation of any board insurance policy covering any portion of fire underwriters the Project. Tenant and Tenant’s agents shall not place any loads upon the floor, walls or other similar body now ceiling of the Premises which would endanger the Building or hereafter constituted relating to the structural elements thereof or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect nor place any harmful liquids in the use or occupancy drainage system of the Premises, Building or as are not related Common Area. No waste materials or refuse shall be dumped upon or permitted to or afforded remain upon any part of the Project except in enclosed trash containers designated for that purpose by Tenant’s improvements or actsLandlord.

Prohibited Uses. (a) Tenant will not useThe uses prohibited under this Lease shall include, occupy or permit the without limitation, use or occupancy of any of the Premises or a portion thereof for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances offices of any governmental authority in agency or bureau of the United States or any way applicable to Tenant state or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), political subdivision thereof; (ii) covenants, conditions, offices or restrictions applicable to such Premises and appearing agencies of record in the office of the county recorder of the county in which such Premises are located on any foreign governmental or before the date on which such Premises became subject to this Lease, or political subdivision thereof; (iii) insurance requirements. offices of any health care professionals or service organization; (biv) schools or other training facilities which are not ancillary to corporate, executive or professional office use; (v) retail or restaurant uses; or (vi) communications firms such as radio and/or television stations. Tenant shall not, without the prior written consent of Landlord (which consent shall not keep be unreasonably withheld, conditioned or permit to be kept any substance indelayed), or conduct or permit to be conducted any operation from, any allow the average occupancy density of the Premises which is not to be in excess of reasonable occupancy densities of similar spaces, as reasonably consistent with the Permitted Use for such Premises determined by Landlord; it being agreed and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. acknowledged by Tenant that (ci) in no event shall Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any average occupancy density of the Premises which exceed the structural loads of floors to violate any governmental permit or walls of zoning requirements or any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation requirements of any insurance policy covering affecting the Premises or the Building, and (ii) it shall be reasonable for Landlord to withhold its consent to any increase in average occupancy density of the Premises if such Premisesdensity will have a materially, adverse impact on the parking facilities of the Project. Tenant further covenants and agrees that Tenant shall not use, or suffer or permit any person or persons to use, the Premises or any part thereof for any use or purpose contrary to the provisions of the rules and regulations set forth in Exhibit D (“Rules and Regulations”), attached hereto, or in violation of Applicable Laws; provided, however, Landlord shall not enforce, change or modify the Rules and Regulations in a discriminatory manner and Landlord agrees that the Rules and Regulations shall not be unreasonably modified or enforced in a manner which will unreasonably interfere with the normal and customary conduct of Tenant’s business. Tenant shall not do or permit anything to be done in or about the Premises which will in any way damage the reputation of the Project or unreasonably obstruct or interfere with the rights of other tenants or occupants of the Building, or injure or annoy them or use or allow the Premises to be used for any improper, unlawful or objectionable purpose, nor shall Tenant sell cause, maintain or permit to be keptany nuisance in, used or sold in on or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.

Prohibited Uses. (a) Tenant will shall not use, occupy do or permit the use or occupancy of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit anything to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance done in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might which will cause a cancellation of any insurance policy covering such the Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles articles, materials, or substances which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articlesinsurance. (fb) Tenant shall not use the Premises or permit anything to be done in or about the Premises which will in any way conflict with any law, statute, ordinance or governmental rule or regulation or requirement of duly constituted public authorities now in force or which may hereafter be enacted, promulgated or created. Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements laws, statutes, ordinances and governmental rules, regulations or requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such including structural changes as do not that relate to or affect the use. (c) Tenant shall not use the Premises for any sexually-oriented business activities, including, without limitation, as an adult store, strip club, or occupancy similar uses. (d) Tenant shall comply with all requirements of any recorded restrictive covenants or bylaws of any owners association affecting the Premises. (e) Tenant shall not permit smoking on or within the Premises at any time. (f) Tenant shall not operate an incinerator or burn trash or garbage within the Premises, the Building, or as surrounding areas. (g) Tenant shall not use the Premises or conduct any activities therein which include or cause excessive noise or which otherwise interfere with the business activities or uses of other tenants occupying other spaces within the Building in which the Premises are located. (h) Tenant shall not permit any objectionable noises or odors to emanate from the Premises; nor take any other action or engage in any activities which would constitute a nuisance or would disturb or endanger other tenants of in the Building; nor permit any unlawful or immoral practice to be carried on or committed within the Premises. (i) Tenant shall not make any structural alterations, additions or improvements to the Premises without the prior written consent of Landlord, which consent may be withheld in Landlord’s sole and absolute discretion. (j) No pets of any kind are allowed. Because this is a commercial project, with various industrial and commercial activities, dogs and other pets are not related to or afforded by Tenant’s improvements or actsallowed under any circumstances. Tenant shall pay Landlord a $500 fine for each violation of this provision.

Prohibited Uses. (a) Tenant will shall not use, occupy or suffer or permit the use of, or occupancy of suffer or permit anything to be done in or anything to be brought into or kept in, the Demised Premises or any part thereof (i) which would violate any of the Premises for any purpose or in any manner which is or may becovenants, directly or indirectlyagreements, in violation terms, provisions and conditions of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”)this Lease, (ii) covenants, conditions, for any unlawful purposes or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Leaseany unlawful manner, or (iii) insurance requirements. which, in the reasonable judgment of Landlord shall in any way (a) impair or tend to impair the appearance or reputation of the Building, (b) Tenant shall not keep impair or permit interfere with or tend to be kept any substance in, impair or conduct or permit to be conducted any operation from, interfere with any of the Premises which is not reasonably consistent Building services or the proper and economic heating, cleaning, air conditioning or other servicing of the Building or Demised Premises, or with the Permitted Use for such Premises and which might emit offensive odors or conditionsuse of any of the other areas of the Building, or make undue noise or create undue vibrations. (c) Tenant shall not commit occasion discomfort, inconvenience or permit to remain any waste annoyance to any of the Premises. (d) Tenant shall not install other tenants or permit to remain any improvements to any occupants of the Premises which exceed Building, whether through the structural loads transmission of floors noise or walls odors or otherwise. Without limiting the generality of any buildings located the foregoing, no food shall be prepared, excepting occasional catered activities in the normal course of business, for consumption on or about the Demised Premises; no intoxicating liquors or alcoholic beverages shall be sold on or about the Demised Premises; no lottery tickets (even where the sale of such tickets is not illegal) shall be sold and no gambling, betting or wagering shall otherwise be permitted on or about the Demised Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant ; no loitering shall not commit or permit to be committed any action or circumstance permitted in or about any the Demised Premises; and no loading or unloading of supplies or other material to or from the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor Demised Premises shall Tenant sell or permit be permitted on the Land except at times and in locations to be keptdesignated by Landlord. The Demised Premises shall be maintained in a sanitary condition, used or sold and all kept free of rodents and vermin. All trash and rubbish shall be suitably stored in or about any of the Demised Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating locations designated by Landlord from time to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or actstime.

Prohibited Uses. (a) Tenant will not use, occupy or permit The Licensee shall use reasonable efforts to ensure that the Authorised Users are aware of the prohibitions on the use of the Licensed Materials set out in this Licence and the Licensee shall use b) Except where this Licence provides otherwise, Authorised Users may not: i) Remove or occupancy alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and all disclaimers as they appear in the Licensed Materials; ii) Systematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, mount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee’s Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work, except where expressly permitted under this Licence; vi) make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or transmit any part of the Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of inter-library lending). c) The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or attempting to carry out any of the Premises foregoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. d) This clause 5) shall continue to apply after termination of this Licence for any purpose or in any manner which is or may be, directly or indirectly, in violation of any reason. (i…) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental Copyright and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.Permissions

Prohibited Uses. (a) Tenant will further covenants and agrees that Tenant shall not use, occupy or suffer or permit any person or persons to use, the Premises or any part thereof for any use or occupancy purpose contrary to the provisions of the "Rules and Regulations" set forth in EXHIBIT D, attached hereto, or in violation of the laws of the United States of America, the State of Arizona, or the ordinances, regulations or requirements of the local municipal or county governing body or other lawful authorities having jurisdiction over the Project, including, without limitation, any such laws, ordinances, regulations or requirements relating to hazardous materials or substances, as those terms are defined by applicable laws now or hereafter in effect. Landlord shall not modify the Rules and Regulations without Tenant's consent, which shall not be unreasonably * Portions redacted pursuant to a request for confidential treatment filed with the Securities and Exchange Commission. withheld or delayed, and which consent shall be deemed to be granted by Tenant so long as such change shall not require Tenant to pay Additional Rent and shall not unreasonably interfere with Tenant's use of the Premises. Such amendment is not binding on Tenant until the tenth (10th) business day after Tenant receives written notice of the change, and no rule shall apply retroactively. The Rules and Regulations do not take precedence over the specific terms and conditions of the lease. Tenant shall not do or permit anything to be done in or about the Premises which will in any way obstruct or interfere with the rights of other tenants or occupants of the Building, or injure or annoy them or use or allow the Premises to be used for any unlawful purpose, nor shall Tenant cause, maintain or permit any nuisance in, on or about the Premises. Tenant shall comply with, and Tenant's rights and obligations under the Lease and Tenant's use of the Premises for any purpose or in any manner which is or may beshall be subject and subordinate to, directly or indirectlyall recorded easements, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, and restrictions now or hereafter affecting the Project, provided that any such easements, covenants, conditions, and restrictions applicable to such Premises hereafter affecting the Project do not materially and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any unreasonably interfere with Tenant's use of the Premises which is and do not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings result in any wayadditional monetary obligation on the part of Tenant other than minor administrative compliance costs. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.

Prohibited Uses. (a) Notwithstanding anything to the contrary set forth herein, so long as Tenant will not use, occupy or permit is open and operating Original Lease the use or occupancy of any Permitted Use set forth in Section 1.6 of the Premises for any purpose or Abstract of Lease in any manner the Premises, and has not committed an event of default which is or may beremains uncured after issuance of required notice and expiration of applicable cure periods, Landlord shall not, directly or indirectly, in violation lease any portion of the shopping center within two hundred (200) feet of the demising walls of the Premises to other tenants or occupants for the following purposes: a liquor store, pet shop an amusement arcade, a funeral home, a shooting gallery or gun and ammunition store, a massage parlor (excluding any nationally recognized massage tenant by way of example but not limitation, Massage Envy), or an adult book store. Tenant Restrictions No Lease Provision Original Lease Abatement No Rent shall be due commencing on the RCD and continuing for a period of three (i3) judicial decisionsmonths ("Abatement Months"). (Lease, orderExhibit B, injunctionsPg. B-1) Original Lease Access LL reserves the right to, writsat all reasonable times, statutesby itself or its duly authorized agents, rulingsemployees and contractors to go upon Original Lease and inspect the Premises and every part thereof, rulesto enforce or carry out the provisions of the Lease, regulationsat its option to make repairs, promulgationsalterations and additions to the Premises or the bldg of which the Premises are a part, directivesto perform any defaulted obligation of T or for any other proper purposes. LL also reserves the right to install or place upon, permits, certificates or ordinances affix to the roof and exterior walls of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoningequipment, environmental signs, displays, antenna, cables and utility conservation matters (hereinafter “Legal Requirements”)any other object or structure of any kind, (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in provided the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant same shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect materially impair the structural integrity of any such buildings in any way. the bldg or interfere w/ T's occupancy. (eLease, Sec. 7.4(B), Pg. 15) Tenant Assignment/Sublease Consent: T may not and shall not commit assign the Lease, in whole or permit to be committed in part, nor sublet all or any action or circumstance in or about any part of the Premises, nor bring license Original Lease concessions or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premiseslease departments therein, nor pledge or encumber by mortgage or other instruments any interest in the Lease ("Transfer") w/out first obtaining the consent of LL, which consent LL shall Tenant sell not unreasonably withhold condition or permit delay. Profit Sharing: No Lease Provision. Assignment Fee: $2,000.00 Permitted Assignment: T may assign its entire interest under the Lease or sublet the Premises to be kepta wholly owned corporation, used affiliate, subsidiary or sold in or about any parent of the Premises T or to any articles which may be prohibited successor to T by a standard form policy purchase, merger, consolidation or reorganization ("Corporate Transfer") w/out the consent of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. LL. Recapture Rights: No Lease Provision. (f) Tenant shallLease, at Tenant’s sole cost and expenseSec. 10.1, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the PremisesPg. 21; Rider, excluding such structural changes as do not relate to or affect the use or occupancy of the PremisesSec. R-14, or as are not related to or afforded by Tenant’s improvements or acts.Pg. Rider-4)

Prohibited Uses. (a) Tenant will not use, occupy or permit the use or occupancy of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant Tenant’s agents shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit suffer to be committed any action waste upon the Premises. Tenant and Tenant’s agents shall not do or circumstance permit anything to be done in or about the Premises or Common Area which will in any way unreasonably obstruct or unreasonably interfere with the rights of any other tenants of the Building, other authorized users of the Common Area, or occupants of neighboring property, or injure or annoy them. Tenant shall not conduct or permit any auction or sale open to the public to be held or conducted on or about the Premises or Common Area. Tenant and Tenant’s agents shall not use or allow the Premises to be used for any unlawful or hazardous purpose or any purpose not permitted by this Lease, nor shall Tenant or Tenant’s agents cause, maintain, or permit any nuisance in, on or about the Premises, . Tenant and Tenant’s agents shall not do or permit anything to be done in or about the Premises nor bring or keep anything therein whichin the Premises which will in any way increase the rate of any insurance upon any portion of the Project or any of its contents, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premisesany portion of the Project or any of its contents, nor shall Tenant or Tenant’s agents keep, use or sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at upon any portion of the Project or any of its contents is increased because of Tenant’s sole particular use of the Premises or that of Tenant’s agents, Tenant shall pay, as Additional Rent, the full cost and expenseof such increase; provided, promptly comply with all Legal Requirements now however this provision shall in force no event be deemed to constitute a waiver of Landlord’s right to declare a default hereunder by reason of the act or which may hereafter be in force and with the requirements conduct of Tenant or Tenant’s agents causing such increase or of any board other rights or remedies of fire underwriters Landlord in connection therewith. Tenant and Tenant’s agents shall not place any loads upon the floor, walls or other similar body now ceiling of the Premises which would endanger the Building or hereafter constituted relating to the structural elements thereof or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect nor place any harmful liquids in the use or occupancy drainage system of the PremisesBuilding or Common Area. No waste materials or refuse shall be dumped upon or permitted to remain upon any part of the Project except in enclosed trash containers designated for that purpose by Landlord. No materials, supplies, equipment, finished products (or semi-finished products), raw materials, or as are not related other articles of any nature shall be stored upon, or be permitted to or afforded by Tenant’s improvements or actsremain on, any portion of the Project outside the Premises.

Prohibited Uses. (a) Notwithstanding any other provision of this Lease, Tenant will shall not useuse the Premises or the Building, occupy or any part thereof, or suffer or permit the use or occupancy of the Premises or the Building or any part thereof by any of the Tenant Parties (i) in a manner which would violate any of the covenants, agreements, terms, provisions and conditions of this Lease or otherwise applicable to or binding upon the Premises; (ii) for any unlawful purposes or in any unlawful manner; (iii) which, in the reasonable judgment of Landlord (taking into account the use of the Building as a combination laboratory, research and development and office building and the Permitted Uses) shall (a) impair the appearance or reputation of the Building; (b) impair, interfere with or otherwise diminish the quality of any of the Building services or the proper and economic heating, cleaning, ventilating, air conditioning or other servicing of the Building or Premises, or the use or occupancy of any of the Premises for any purpose Common Areas; (c) occasion discomfort, inconvenience or annoyance in any material respect (and Tenant shall not install or use any electrical or other equipment of any kind which, in the reasonable judgment of Landlord, will cause any such impairment, interference, discomfort, inconvenience, annoyance or injury), or cause any injury or damage to any occupants of the Premises or other tenants or occupants of the Building or their property; or (d) cause air emissions not permitted by Legal Requirements, laboratory odors or noises or any unusual or other objectionable odors, noises or emissions to emanate from the Premises; (iv) in a manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or inconsistent with the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office operation and/or maintenance of the county recorder Building as a first-class combination office, research, development and laboratory facility; (v) for any fermentation processes whatsoever; or (vi) in a manner which shall increase such insurance premiums on the Building or on property located therein over that applicable when Tenant first took occupancy of the county in which Premises hereunder, unless Tenant pays for such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirementsincrease. (b) With respect to the use and occupancy of the Premises and the Common Areas, Tenant shall not keep will not: (i) place or maintain any signage (except as set forth in Section 12.2 below), trash, refuse or other articles in any vestibule or entry of the Premises, on the footwalks or corridors adjacent thereto or elsewhere on the exterior of the Premises, nor obstruct any driveway, corridor, footwalk, parking area, mall or any other Common Areas; (ii) permit undue accumulations of or burn garbage, trash, rubbish or other refuse within or without the Premises; (iii) permit the parking of vehicles so as to be kept interfere with the use of any substance indriveway, corridor, footwalk, parking area, or other Common Areas; (iv) receive or ship articles of any kind outside of those areas reasonably designated by Landlord; (v) conduct or permit to be conducted any operation fromauction, any going out of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditionsbusiness sale, or make undue noise or create undue vibrations. bankruptcy sale (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premisesunless directed by court order), or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now type sale in or hereafter constituted relating connected with the Premises; (vi) use the name of Landlord, or any of Landlord’s affiliates in any publicity, promotion, trailer, press release, advertising, printed, or display materials without Landlord’s prior written consent; or (vii) except in connection with Alterations (hereinafter defined) approved by Landlord or the Tenant’s Work, cause or permit any hole to be drilled or affecting the use or occupancy of all made in any part of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or actsBuilding.

Prohibited Uses. (a) Tenant will not use, occupy or permit the use or occupancy of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant Tenant’s agents shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit suffer to be committed any action waste upon the Premises. Tenant and Tenant’s agents shall not do or circumstance permit anything to be done in or about the Premises or Common Area which will in any way obstruct or interfere with the rights of any authorized users of the Common Area or occupants of neighboring property, or injure or unreasonably annoy them. Tenant shall not conduct or permit any auction or sale open to the public to be held or conducted on or about the Premises or Common Area. Tenant and Tenant’s agents shall not use or allow the Premises to be used for any unlawful, immoral or hazardous purpose or any purpose not permitted by this Lease, nor shall Tenant or Tenant’s agents cause, maintain, or permit any nuisance in, on or about the Premises, . Tenant and Tenant’s agents shall not do or permit anything to be done in or about the Premises or Common Area nor bring or keep anything therein whichin the Premises or Common Area which will in any way increase the rate of any insurance upon the Premises or Common Area or any part thereof or any of its contents, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premisesthe Premises or Common Area or any part thereof or any of its contents, nor shall Tenant or Tenant’s agents keep, use or sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance unless upon the Premises or Common Area or any part thereof or any of its contents is increased because of the acts or omissions of Tenant provides additional insurance coverage extending protection or Tenant’s agents, Tenant shall pay, as Additional Rent, the full cost of such increase; provided however this provision shall in no event be deemed to cover all risks associated constitute a waiver of Landlord’s right to declare a default hereunder by reason of such increase or of any other rights or remedies of Landlord in connection with those articles. such increase. Tenant and Tenant’s agents shall not place any loads upon the floor, walls or ceiling of the Premises which would endanger the Premises or the structural elements thereof, nor place any harmful liquids in the drainage system of the Premises. No waste materials or refuse shall be dumped upon or permitted to remain upon any part of the Premises or Common Area except in enclosed trash containers. No materials, supplies, equipment, finished products (f) Tenant shallor semifinished products), raw materials, or other articles of any nature shall be stored upon, or be permitted to remain on, any portion of the Common Area. Landlord shall have the right to require Tenant, at Tenant’s sole cost own expense and expensewithin a reasonable period of time, promptly comply with all Legal Requirements now in force to use Tenant’s commercially reasonable efforts to terminate or which may hereafter be in force and control any picketing, work stoppage or other concerted activity related to Tenant’s business operations to the extent necessary to eliminate any interference with the requirements operation of any board of fire underwriters the Common Area or other similar body now or hereafter constituted relating to or affecting tenants who use the use or occupancy Common Area. Nothing contained in this paragraph shall be construed as placing Landlord in an employer-employee relationship with any of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements employees or actswith any other employees who may be involved in such activity.

Prohibited Uses. (a) Tenant will shall not use, occupy or suffer or permit the use of, or occupancy of suffer or permit anything to be done in or anything to be brought into or kept in, the Demised Premises or any part thereof (i) which would violate any of the Premises for any purpose or in any manner which is or may becovenants, directly or indirectlyagreements, in violation terms, provisions and conditions of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”)this Lease, (ii) covenants, conditions, for any unlawful purposes or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Leaseany unlawful manner, or (iii) insurance requirements. which, in the reasonable judgment of Landlord shall in any way (a) impair or tend to impair the appearance or reputation of the Building, (b) Tenant shall not keep impair or permit interfere with or tend to be kept any substance in, impair or conduct or permit to be conducted any operation from, interfere with any of the Premises which is not reasonably consistent Building services or the proper and economic heating, cleaning, air conditioning or other servicing of the Building or with the Permitted Use for such Premises and which might emit offensive odors or conditionsuse of any of the other areas of the Building, or make undue noise or create undue vibrations. (c) Tenant shall not commit occasion discomfort, inconvenience or permit to remain any waste annoyance to any of the Premises. (d) Tenant shall not install other tenants or permit to remain any improvements to any occupants of the Building, whether through the transmission of noise or odors or otherwise. Without limiting the generality of the foregoing, no food shall be prepared or served for consumption by the general public on or about the Demised Premises; no intoxicating liquors or alcoholic beverages shall be sold or otherwise permitted on or about the Demised Premises; no lottery tickets (even where the sale of such tickets is not illegal) shall be sold and no gambling, betting or wagering shall otherwise be permitted on or about the Demised Premises; no machinery shall be operated in the Demised Premises which exceed the structural loads of floors or walls if such operation involves vibratory motion of any buildings located kind; no loitering shall be permitted on such or about the Demised Premises, ; and no loading or adversely affect unloading of supplies or other material to or from the mechanical, plumbing or electrical systems of any such buildings, or affect Demised Premises shall be permitted on the structural integrity of any such buildings Land except at times and in any way. (e) Tenant shall not commit or permit locations to be committed any action or circumstance designated by Landlord. The Demised Premises shall be maintained in or about any a sanitary condition, and kept free of rodents and vermin. All trash and rubbish shall be suitably stored in the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Demised Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating locations designated by Landlord from time to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or actstime.

Prohibited Uses. (a) Tenant will not use, occupy or permit the use or occupancy of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant Tenant’s agents shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit suffer to be committed any action waste upon the Premises. Tenant and Tenant’s agents shall not do or circumstance permit anything to be done in or about any of the Premises, Building, Project or Common Area which will in any way obstruct or interfere with the rights of any other tenants of the Building or Project, other authorized users of the Common Area, or occupants of neighboring property, or injure them. Tenant shall not conduct or permit any auction or sale open to the public to be held or conducted on or about the Premises, Building, Project or Common Area. Tenant and Tenant’s agents shall not use or allow the Premises to be used for any unlawful, or hazardous purpose or any purpose not permitted by this Lease, nor shall Tenant or Tenant’s agents cause, maintain, or permit any nuisance in, on or about the Premises, Building, Project or Common Area. Tenant shall not overload existing electrical systems or other mechanical equipment servicing the Building, impair the efficient operation of the sprinkler system or the heating, ventilation or air conditioning equipment within or servicing the Building or damage, overload or corrode the sanitary sewer system. Tenant and Tenant’s agents shall not do or permit anything to be done in or about the Premises nor bring or keep anything therein whichin the Premises which will in any way increase the rate of any insurance upon any portion of the Project or any of its contents, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premisesany portion of the Project or any of its contents, nor shall Tenant or Tenant’s agents keep, use or sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at upon any portion of the Project or any of its contents is increased because of Tenant’s sole particular use (as distinct from normal office use or normal ancillary use) of the Premises or that of Tenant’s agents, Tenant shall pay, as Additional Rent, the full cost and expenseof such increase; provided, promptly comply with all Legal Requirements now however this provision shall in force no event be deemed to constitute a waiver of Landlord’s right to declare a default hereunder by reason of the act or which may hereafter be in force and with the requirements conduct of Tenant or Tenant’s agents causing such increase or of any board other rights or remedies of fire underwriters Landlord in connection therewith. Tenant and Tenant’s agents shall not place any loads upon the floor, walls or other similar body now ceiling of the Premises which would endanger the Building or hereafter constituted relating to the structural elements thereof or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect nor place any harmful liquids in the use or occupancy drainage system of the PremisesBuilding or Common Area. No waste materials or refuse shall be dumped upon or permitted to remain upon any part of the Project except in enclosed trash containers designated for that purpose by Landlord. No materials, supplies, equipment, finished products (or semi-finished products), raw materials, or as are not related other articles of any nature shall be stored upon, or be permitted to or afforded by Tenant’s improvements or actsremain on, any portion of the Project outside the Premises.

Prohibited Uses. (a) Tenant will fmiher covenants and agrees that Tenant shall not use, occupy or suffer or permit any person or persons to use, the Premises or any part thereof for any use or occupancy purpose contrary to the provisions of the Rules and Regulations set forth in Exhibit D, attached hereto, or in violation of the laws of the United States of America, the State of California, or the ordinances, regulations or requirements of the local municipal or county governing body or other lawful authorities havingjurisdiction over the Project, including, without limitation, any such laws, ordinances, regulations or requirements relating to hazardous materials or substances, as those terms are defined by applicable laws now or hereafter in effect. Tenant shall not do or permit anything to be done in or about the Premises which will in any way damage the reputation of the Project or obstruct or interfere with the rights of other tenants or occupants of the Building, or injure or annoy them or use or allow the Premises to be used for any improper, unlawful or objectionable purpose, nor shall Tenant cause, maintain or permit any nuisance in, on or about the Premises. Tenant shall comply with, and Tenant's rights and obligations under the Lease and Tenant's use of the Premises for any purpose or in any manner which is or may beshall be subject and subordinate to, directly or indirectlyall recorded easements, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, and restrictions now or restrictions applicable to such Premises and appearing of record in hereafter affecting the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Project. Tenant shall not keep cause or permit to be kept any substance in"Hazardous Substance," as that term is defined below, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used maintained, used, stored, produced, generated or sold disposed of (into the sewage or waste disposal system or otherwise) on or in the Premises by Tenant or Tenant's agents, employees, contractors, invitees, assignees or sublessees, without first obtaining Landlord's written consent. Tenant shall immediately notify, and shall direct Tenant's agents, employees contractors, invitees, assignees and sublessees to immediately notify, Landlord of any incident in, on or about the Premises, the Building or the Project that would require the filing of a notice under any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. federal, state, local or quasi-governmental law (f) Tenant shallwhether under common law, at Tenant’s sole cost and expensestatute or otherwise), promptly comply with all Legal Requirements now in force ordinance, decree, code, ruling, award, rule, regulation or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body guidance document now or hereafter constituted enacted or promulgated, as amended from time to time, in any way relating to or affecting the use or occupancy of all of the Premisesregulating any Hazardous Substance. As used herein, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises"Hazardous Substance" means any substance which is toxic, ignitable, reactive, or corrosive and which is regulated by any local government, the State of California, or the United States government. "Hazardous Substance" includes any and all material or substances which are defined as are not related "hazardous waste," "extremely hazardous waste" or a "hazardous substance" pursuant to state, federal or afforded by Tenant’s improvements or actslocal governmental law. "Hazardous Substance" also includes asbestos, polychlorobiphenyls (i.e., PCB's) and petroleum.

Prohibited Uses. (a) Tenant will not use, occupy or permit the use or occupancy of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant Tenant’s Agents shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit suffer to be committed any action waste upon the Premises. Tenant and Tenant’s Agents shall not do or circumstance permit anything to be done in or about the Premises or Common Area which will in any way obstruct or interfere with the rights of any authorized users of the Common Area or occupants of the Adjacent Parcel (or improvements thereon), or injure them. Tenant shall not conduct or permit any auction or sale open to the public to be held or conducted on or about the Premises or Common Area. Tenant and Tenant’s Agents shall not use or allow the Premises to be used for any unlawful, immoral or, except as expressly permitted by this Lease, hazardous purpose or any purpose not permitted by this Lease, nor shall Tenant or Tenant’s Agents cause, maintain, or permit any nuisance in, on or about the Premises, . Tenant and Tenant’s agents shall not do or permit anything to be done in or about the Premises or Common Area nor bring or keep anything therein whichin the Premises or Common Area which will in any way increase the rate of any insurance upon any portion of the Project or any of its contents, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premisesany portion of the Project or any of its contents, nor shall Tenant or Tenant’s Agents keep, use or sell or permit to be kept, used or sold in or about any of the Premises or Common Area any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at upon any portion of the Project or any of its contents is increased because of Tenant’s sole particular use of the Premises or Common Area or that of Tenant’s agents, Tenant shall pay, as Additional Rent, the full cost and expenseof such increase; provided, promptly comply with all Legal Requirements now however this provision shall in force no event be deemed to constitute a waiver of Landlord’s right to declare a default hereunder by reason of the act or which may hereafter be in force and with the requirements conduct of Tenant or Tenant’s agents causing such increase or of any board other rights or remedies of fire underwriters Landlord in connection therewith. Tenant and Tenant’s agents shall not place any loads upon the floor, walls or other similar body now ceiling of the Premises which would endanger the Building or hereafter constituted relating to the structural elements thereof or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect nor place any harmful liquids in the use or occupancy drainage system of the PremisesBuilding or Common Area. No waste materials or refuse shall be dumped upon or permitted to remain upon any part of the Project except in enclosed trash containers designated for that purpose by Landlord. No materials, supplies, equipment, finished products (or semi-finished products), raw materials, or as are not related other articles of any nature shall be stored upon, or be permitted to or afforded by Tenant’s improvements or actsremain on, any portion of the Project outside the Premises.

Prohibited Uses. (a) Notwithstanding any other provision of this Lease, Tenant will shall not useuse the Premises or the Building, occupy or any part thereof, or suffer or permit the use or occupancy of the Premises or the Building or any part thereof by any of the Tenant Parties (i) in a manner which would violate any of the covenants, agreements, terms, provisions and conditions of this Lease or any Permitted Encumbrance; (ii) for any unlawful purposes or in any unlawful manner; (iii) which, in the reasonable judgment of Landlord (taking into account the use of the Building as a combination office and laboratory building and the Permitted Uses) shall (A) impair the appearance or marketability of the Building; (B) impair, interfere with or otherwise diminish the quality of any of the Building services or the proper and economic heating, cleaning, ventilating, air conditioning or other servicing of the Building or Premises, or the use or occupancy of any of the Premises for any purpose Common Areas; (C) occasion discomfort, inconvenience or annoyance in any material respect, or cause any injury or damage to any other occupants of the Property or neighboring properties or their property; or (D) cause harmful air emissions or any unusual or other objectionable odors, noises or emissions to emanate from the Premises; (iv) in a manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or inconsistent with the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office operation and/or maintenance of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, Building as a first-class combination office and laboratory facility; or (iiiv) insurance requirementsfor any fermentation processes whatsoever other than biological manufacturing of protein therapeutics. (b) With respect to the use and occupancy of the Premises and the Common Areas, Tenant shall not keep will not: (i) place or maintain any trash, refuse or other articles in any vestibule or entry of the Premises, on the footwalks or corridors adjacent thereto or elsewhere on the exterior of the Premises, nor, subject to Section 12 below, place or maintain any signage on the exterior of the Premises, nor obstruct any driveway, corridor, footwalk, parking area, mall or any other Common Areas; (ii) permit undue accumulations of or burn garbage, trash, rubbish or other refuse within or without the Premises; (iii) permit the parking of vehicles so as to be kept interfere with the use of any substance indriveway, corridor, footwalk, parking area, or other Common Areas; (iv) receive or ship articles of any kind outside of those areas reasonably designated by Landlord; (v) conduct or permit to be conducted any operation fromauction, going out of business sale, bankruptcy sale (unless directed by court order), or other similar type sale in or connected with the Premises; (vi) use the name of the Building, the Property, Landlord, or any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors Landlord’s affiliates or conditionssubsidiaries or any photograph, film, drawing, or make undue noise other depiction or create undue vibrationsrepresentation of the Building and/or the Property or any part thereof, which contains signage or distinctive architectural characteristics that cause the scene photographed, filmed, drawn, depicted, or represented to be identifiable as being the Building and/or the Property, in any publicity, promotion, trailer, press release, advertising, printed, or display materials without Landlord’s prior written consent; or (vii) except in connection with Tenant’s Work and/or Alterations (hereinafter defined) approved by Landlord, cause or permit any hole to be drilled or made in any exterior, load bearing or structural wall of the Building. (c) Tenant At all times that animals are transported within the Common Areas, they shall not commit be transported in an appropriate cage or permit other container. At no time shall any animals, animal waste, food or supplies relating to remain any waste the animals be brought into, transported through, or delivered to any the ▇▇▇▇▇ Street entrance of the PremisesBuilding. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.

Prohibited Uses. (a) No overnight lodging shall be permitted on the Premises. Tenant will not useshall not, occupy without Landlord’s prior written consent, keep anything within the Premises or permit the use or occupancy of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with other than the Permitted Use for such Premises and which might emit offensive odors Use) that increases the insurance premium cost or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of invalidates any insurance policy covering such Premises, nor shall Tenant sell carried on the Premises or permit to be other parts of the Project. All property kept, used stored or sold in or about any of maintained within the Premises any articles which may by Tenant shall be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost risk. Tenant shall not conduct within the Premises any fire, auction, bankruptcy, “going out of business”, “lost our lease”, or similar sales or operate within the Premises a “wholesale” or “factory outlet” store, a cooperative store, a “second-hand” store, a “surplus” store or a store commonly referred to as a “discount house”. Tenant shall not advertise that it sells its products or services at “discount”, “cut-price”, or “cut-rate” prices. Tenant shall not (a) permit any objectionable or unpleasant odors to emanate from the Premises; (b) place or permit any radio, television, loudspeaker or amplifier on the roof or outside the Premises or where the same can be seen or heard from outside the Premises; (c) except as otherwise set forth herein, place any antenna, awning or other projection on the exterior of the Premises; (d) take any other action that would constitute a legal nuisance or would materially disturb or endanger other tenants of the Project or unreasonably interfere with their use of their respective premises; (e) operate any nightclub, bar or other business serving alcoholic beverages, adult bookstore, massage parlor, head shop, or store selling marijuana or drug paraphernalia, any adult entertainment or sexually oriented business; (f) violate any governmental law, ordinance, rule or regulation, or (g) operate any business that would violate the exclusives set forth on Exhibit H. Tenant shall take good care of the Premises and keep the same free from material physical waste at all times. Tenant shall keep the Premises neat, clean and free from dirt or rubbish at all times, and shall store all trash and garbage within the Premises, and provide for the regular pick-up of such trash and garbage at Tenant’s expense. Receiving and delivery of goods and merchandise and removal of garbage and trash shall be made only in the manner and areas prescribed by Landlord. Tenant shall not operate an incinerator or burn trash or garbage within the Project. Tenant shall maintain all display windows in a neat, promptly attractive condition, and shall keep all display windows, exterior electric signs and exterior lighting under any canopy in front of the Premises lighted from dusk until 11:00 p.m. every day, including Sundays and holidays. Tenant shall procure at its sole expense all permits and licenses required for the transaction of business in the Premises and otherwise comply with all Legal Requirements now in force or which may hereafter be in force applicable laws, ordinances, and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or actsgovernmental regulations.

Prohibited Uses. (a) Tenant will further covenants and agrees that it shall not use, occupy or suffer or permit any person or persons to use, the Premises or any part thereof for any use or occupancy purpose contrary to the provisions of any of the Premises for any purpose Exhibit D, attached hereto, or in any manner which is or may be, directly or indirectly, in violation of any the laws of the United States of America, the State of California, or the ordinances, regulations or requirements of the local municipal or county governing body or other lawful authorities having jurisdiction over the Building; provided however that Landlord agrees that the Rules and Regulations shall not be (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates modified or ordinances of any governmental authority enforced in any way applicable by Landlord so as to interfere with the Permitted Use, or (ii) discriminatorily modified or enforced against Tenant. Landlord agrees that nothing in the Rules and Regulations of the Building shall be used to prohibit or unreasonably interfere with the conduct of any business from the Premises which Tenant is permitted to conduct. In the event any other tenant or occupant of the Building fails to comply with the Rules and Regulations, and 804296.08/LAH4321-047/10-7-08/nng/law -▇▇- ▇▇▇▇▇ ▇▇▇▇ ▇▇▇▇▇[▇▇▇▇▇ ▇▇▇▇ Lease] such non-compliance unreasonably and materially interferes with Tenant's use of the Premises, including but not limited Landlord shall use reasonable efforts to zoning, environmental cause such other tenants and/or occupants to comply with the Rules and utility conservation matters (hereinafter “Legal Requirements”), (ii) Regulations. Tenant shall comply with all recorded covenants, conditions, and restrictions, and the provisions of all ground or restrictions applicable underlying leases, now or hereafter affecting the Real Property which have been provided by Landlord to such Tenant in writing, and shall not at any time use or occupy or allow any person to use or occupy the Premises and appearing of record or the Building or do or permit anything to be done or kept in the office Premises or the Building in any manner which: (i) violates any certificate of occupancy in force for the county recorder of Premises or the county in which such Building; (ii) causes or is likely to cause damage to the Real Property, the Building, the Premises are located on or before the date on which such Premises became subject to this Leaseany equipment, facilities or other systems therein; (iii) insurance requirements. (b) Tenant shall not keep other than conducting normal banking operations from its Premises, results in repeated demonstrations, bomb threats or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any other events which require evacuation of the Premises which is not reasonably consistent Building or otherwise disrupt the use, occupancy or quiet enjoyment of the Building by other tenants and occupants; or (iv) materially interferes with the Permitted Use for such Premises and which might emit offensive odors transmission or conditionsreception of microwave, television, radio or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any other communications signals by antennae located on the roof of the Premises. (d) Tenant shall not install Building or permit to remain any improvements to any of elsewhere in the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shallBuilding. Tenant, at Tenant’s sole cost and 's expense, promptly shall comply with all Legal Requirements laws, rules, orders, ordinances, directions, regulations, and requirements of federal, state, county and municipal authorities, now in force or which may hereafter be in force and with the requirements of force, which shall impose any board of fire underwriters duty or other similar body now or hereafter constituted requirement relating to the use, occupation or affecting the use or occupancy of all alteration of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.

Prohibited Uses. 9.1 Not to use the Premises for any business connected with the Motor Trade or for any public meeting exhibition or entertainment or as a hotel club or amusement arcade or permit any musical instrument radio television or other sound emitting equipment to be operated so as to be audible from outside the Premises 9.2 Not to engage in any works or other operations or permit or store on the Property any goods or other articles which may by reason of smell infection or radioactivity affect any other goods or articles (of whatever kind and however sensitive) elsewhere upon the Estate or generate an excessive degree of noise and/or dust which may constitute a breach of the planning consent FIFTH SCHEDULE (a) Title numbered BK260648 in H M Land Registry (b) Title numbered BK291692 in H M Land Registry (relating to the Common Parts) (c) The Registered Transfers (d) The Outline Planning Consent Number 622867 issued by Bracknell Forest Borough Council on 7th October 1997. SIXTH SCHEDULE Guarantee provisions 1. That the Tenant will not use, occupy or permit at all times during the use or occupancy Term pay the Rents and all other sums covenanted to be paid by the Tenant at the respective times and in the manner appointed for payment thereof and also will duly perform and observe and keep the several covenants stipulations and conditions on the part of the Tenant to be performed and observed and kept and that the Guarantor will pay and make good to the Landlord all losses costs and expenses sustained by the Landlord through the default of the Tenant in respect of any of the Premises for before-mentioned matters PROVIDED ALWAYS that any purpose neglect or forbearance of the Landlord in endeavouring to obtain payment of the Rents and other sums as and when the same shall become due or any delay on the part of the Landlord to take any steps to enforce performance or observance of the said several covenants stipulations and conditions shall not release or in any manner which way lessen or affect the liability of the Guarantor under the guarantee on the part of the Guarantor hereinbefore contained 2. That if the Tenant being an individual shall become bankrupt or if the Tenant for the time being is or may be, directly or indirectly, a company and shall enter into liquidation and the Tenant's trustee in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant bankruptcy or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office Liquidator of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep disclaim this Lease and if the Landlord shall within three months after such disclaimer by notice require the Guarantor or permit the Guarantor's personal representatives or assigns to be kept any substance in, or conduct or permit to be conducted any operation from, any accept a lease of the Premises for a term commensurate with the residue which if there had been no disclaimer would have remained of the Term at the same Rents and under the like covenants conditions provisions agreements and declarations as are reserved by and contained in this Lease (the said new lease and the rights and liabilities thereunder to take effect from the date of the said disclaimer) then and in such case the Guarantor or the Guarantor's personal representatives or assigns shall accept such lease accordingly and execute a counterpart thereof and pay the Landlord's solicitors' costs and disbursements of and incidental thereto 3. This guarantee shall enure for the benefit of the successors and assigns of the Landlord under this Lease without the necessity for any assignment of the benefit thereof 4. This guarantee is also to take effect immediately on the assignment of the Lease to the Tenant under clause 5.8 hereof and is to remain in force so long as and to the extent that the Tenant is not reasonably consistent released by law from liability for the Tenant's covenants in the Lease 5. In the context of these guarantee provisions reference to the Tenant are to the assignee only (in its capacity as Tenant) with respect to whom his guarantee is given THE COMMON SEAL of T A FISHER & SONS LIMITED was hereunto affixed in the Permitted Use for such Premises presence of:- ▇▇▇▇▇▇▇▇ /s/J. Fisher Secretary /s/M. Stewart THE COMMON SEAL of WELLINGTON ▇▇▇▇ ▇▇▇▇GEMENT LIMITED w▇▇ ▇▇▇▇▇▇▇o affixed in the presence of:- Director /s/J. Fisher Secretary /s/M. Stewart EXECUTED AS A DEED by SAVILLE S▇▇▇▇▇▇ (▇K) LIMITED by ▇▇▇▇▇▇▇▇ /s/Christopher A. Hanson ▇▇▇▇▇▇ary /s/Lisa Miller EXECUTED AS A DEED ▇▇ ▇▇▇▇▇▇▇ ▇▇▇▇▇▇▇ ▇LC by Directo▇ /▇/▇▇▇▇ ▇. Boyle, III Secretary /▇/▇▇▇▇ Miller ▇▇▇▇▇NE OFFICE SPECIFICAT▇▇▇ UNITS 35 - 38 WELLINGTON BUSINESS PARK ▇▇▇▇▇ ▇▇▇▇ CROWTHORNE BERKSHIRE. Approximate Schedule of Accommodation m2 (ft2) Unit Nett Int. 36 289 (3106) 37 317 (3407) 38* 317 (3407) The Buildings: Generally comprise the construction of a two storey office unit with traditional brick elevations; in-situ concrete ground floor slab; pre-cast concrete first floor and which might emit offensive odors stairs; structural steel frame; pitched roof covered with BSC Colourcoat HP 200 (or conditions, or make undue noise or create undue vibrations. (cequal) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the plastic coated steel sheeting; double glazed windows and doors; raised particle access floors; air conditioning; mechanical, plumbing or electrical systems of any such buildingsand sanitary installations; floor, or affect the structural integrity of any such buildings in any waywall and ceiling finishes. *Unit 38 shell construction @ Ground Floor. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.

Prohibited Uses. (a) Tenant will not useThe uses prohibited under this Lease shall include, occupy or permit the without limitation, use or occupancy of any of the Premises or a portion thereof for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances offices of any governmental authority in agency or bureau of the United States or any way applicable to Tenant state or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), political subdivision thereof; (ii) covenants, conditions, offices or restrictions applicable to such Premises and appearing agencies of record in the office of the county recorder of the county in which such Premises are located on any foreign governmental or before the date on which such Premises became subject to this Lease, or political subdivision thereof; (iii) insurance requirements. offices of any health care professionals or service organization (bbut excluding any health care professionals engaged in the business of life sciences research); (iv) schools or other training facilities which are not ancillary to corporate, executive or professional office use; (v) retail or restaurant uses; or (vi) communications firms such as radio and/or television stations. Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any allow occupancy density of use of the Premises which is not reasonably consistent with greater than one (1) person for each 150 square feet of the Permitted Use for such Premises Premises. Tenant further covenants and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) agrees that Tenant shall not commit use, or suffer or permit any person or persons to remain use, the Premises or any waste part thereof for any use or purpose contrary to any the provisions of the Premises. (dRules and Regulations set forth in Exhibit D, attached hereto, or in violation of the laws of the United States of America, the State of California, or the ordinances, regulations or requirements of the local municipal or county governing body or other lawful authorities having jurisdiction over the Project) including, without limitation, any such laws, ordinances, regulations or requirements relating to hazardous materials or substances, as those terms are defined by applicable laws now or hereafter in effect. Tenant shall not install do or permit anything to remain any improvements to any of be done in or about the Premises which exceed will in any way materially damage the structural loads reputation of floors the Project or walls obstruct or interfere with the rights of any buildings located on such Premisesother tenants or occupants of the Building, or adversely affect injure or annoy them or use or allow the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit Premises to be committed used for any action improper, unlawful or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premisesobjectionable purpose, nor shall Tenant sell cause, maintain or permit to be keptany nuisance in, used or sold in on or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Premises. Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly shall comply with all Legal Requirements now in force or which may hereafter be in force recorded covenants, conditions, and with the requirements of any board of fire underwriters or other similar body restrictions now or hereafter constituted relating to or affecting the use or occupancy Project and Landlord shall, upon request from Tenant, provide Tenant with copies of all recorded covenants, conditions and restrictions currently affecting the Project and will notify Tenant and provide copies to Tenant of any future covenants, conditions, and restrictions affecting the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or actsProject.

Prohibited Uses. Lessee agrees at all times to comply with the following: (a) Tenant will not Lessee shall at no time use, occupy or permit the use of, the Leased Premises in a manner that is contrary to applicable federal, state, or occupancy of any of the Premises for any purpose or in any manner which is or may belocal laws, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulingsordinances, rules, or regulations, promulgationswhich shall include, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not be limited to zoningto, environmental applicable Federal Aviation Administration (“FAA”) rules and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions regulations and applicable to such Premises and appearing of record in regulations for the office use of the county recorder of the county in which such Premises are located on Airport as may from time to time be promulgated by MDC or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements.City; (b) Tenant Lessee shall not keep permit any permanent, unshielded light or permit illumination source to be kept cause glare as viewed from any substance instreet, adjacent properties or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations.operating aircraft; (c) Tenant Lessee shall not commit cause or permit the burial or storage above ground on the Leased Premises of any hazardous waste or materials, as defined by federal or state law, except in accordance with applicable federal, state, or local laws, ordinances, regulations and rules, as may be adopted or amended from time to remain any waste to any of the Premises.time; (d) Tenant Lessee shall not install cause or permit to remain any improvements to any of use or activity on the Leased Premises which exceed that may create a hazardous condition for aircraft operating at the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way.Airport; (e) Tenant Lessee shall not commit or permit allow the Leased Premises to be committed any action used for parking of motor vehicles, motorcycles, or circumstance motor driven equipment by anyone other than customers, employees, or contractors of Lessee except as may be authorized by the Director of Airports, with all such parking being limited to areas designated by the Department of Airports for such parking. Lessee shall not be in or about default for the improper parking of vehicles over which neither Lessee nor any of the Premisesits sublessees, nor bring customers, employees, or keep anything therein which, directly or indirectly, would or might cause a cancellation of contractors have any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles.control; and (f) Tenant shallLessee shall not operate, at Tenant’s sole cost and expensenor permit the operation of, promptly comply a car rental business from the Leased Premises, unless the Lessee or the operator of said car rental business has executed a car rental concession or permit agreement with all Legal Requirements now MDC or City; and (g) Lessee shall not allow airline passenger operations to be conducted on the Leased Premises. The Leased Premises shall not be used for any use that is disreputable or creates extraordinary fire hazards or results in force an increased rate of insurance on the Leased Premises or which may hereafter be in force and with its contents or the requirements storage of any board hazardous materials or substances. If, because of fire underwriters an act on the party of Lessee, the rate of insurance on the Leased Premises, its facilities or its contents increases, Lessee shall pay to Landlord the amount of such increase on demand, and acceptance of such payment shall not constitute a waiver of any of Landlord’s other similar body now rights. Lessee shall conduct its business and control each other Lessee party or hereafter constituted relating agent, so as not to create any nuisance or affecting the use interfere with other Lessees or occupancy of all Landlord in its management of the Leased Premises, excluding such structural changes as do not relate its facilities or contents. Subject to or affect Landlord’s reasonable security measures and the use or occupancy of Rules and Regulations described in Article 17.06, Lessee and its agents and employees will have access to the PremisesLeased Premises 24 hours per day, or as are not related to or afforded by Tenant’s improvements or acts7 days per week.

Prohibited Uses. (a) Tenant will further covenants and agrees that Tenant shall not use, occupy or suffer or permit any person or persons to use, the Premises or any part thereof for any use or purpose in violation of the laws of the United States of America, the State of California, or the ordinances, regulations or requirements of the local municipal or county governing body or other lawful authorities having jurisdiction over the Project) including, without limitation, DOCPROPERTY "Document number" 4884-2045-4146. DOCPROPERTY "Document version" 4 DOCPROPERTY "Client" 186772. DOCPROPERTY "Matter" 00003/ SAVEDATE \@ M-d-yy 3-21-23/ DOCPROPERTY "User Init" mem/ DOCPROPERTY "Typist Init" ejs DOCPROPERTY "Footer Notes" HEALTHPEAK[Towers at Sierra Point][Tempest Therapeutics, Inc.] any such laws, ordinances, regulations or requirements relating to hazardous materials or substances, as those terms are defined by Applicable Laws now or hereafter in effect, or any Underlying Documents. Landlord shall have the right to impose reasonable and customary rule and regulations regarding the use of the Project, as reasonably deemed necessary by Landlord with respect to the orderly operation of the Project, and Tenant shall comply with such reasonable rules and regulations, which shall not be enforced in a manner intended to discriminate against Tenant. In the event of a conflict between the rules and regulations and the terms of this Lease, the terms of this Lease shall control. Tenant shall not use or occupancy of allow the Premises to be used for any improper, unlawful, or objectionable purpose or do or permit anything to be done in or about the Premises which will cause, maintain or permit any nuisance in, on or about the Premises. Tenant shall comply with, and ▇▇▇▇▇▇'s rights and obligations under the Lease and ▇▇▇▇▇▇'s use of the Premises for any purpose or in any manner which is or may beshall be subject and subordinate to, directly or indirectlyall recorded easements, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or and restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or actsProject.

Prohibited Uses. Tenant shall comply with all of the following: (a) Tenant will shall not use, occupy do or permit anything to be done in or about the use or occupancy Premises nor bring nor keep anything therein which could cause a cancellation of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or insurance policy covering the Premises, including but not limited to zoningthe Building, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, any part thereof or restrictions applicable to such Premises and appearing any of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirementsits contents. (b) Tenant shall not keep do or permit anything to be kept any substance in, done in or conduct or permit to be conducted any operation from, any of about the Premises which is not reasonably consistent would in any way obstruct or interfere with the Permitted Use for such Premises and which might emit offensive odors rights of other tenants or conditions, occupants of the Building or make undue noise injure or create undue vibrationsannoy them. (c) Tenant shall not commit use or permit allow the Premises to remain be used for my unlawful purpose or in any waste to any of the Premisesmanner that constitutes a public nuisance. (d) Tenant shall not install cause, maintain, suffer or permit to remain any improvements to any of nuisance in, on or about the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit permit noise or permit odors in the Premises which are objected to be committed by Landlord or by any action tenant or circumstance in or about any occupant of the PremisesBuilding, nor bring and, upon written notice from Landlord, Tenant shall immediately cease and desist from causing such noise or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articlesodor. (f) Tenant shallshall not commit or allow to be committed any waste in or upon the Premises. (g) Tenant shall not use or permit the Premises or any portion thereof to be used as living quarters, at Tenant’s sole cost sleeping quarters or for lodging purposes or for any unlawful purposes. (h) Tenant shall not conduct any auctions, liquidation, going out of business, fire or bankruptcy sales on or about the Premises. (i) Tenant agrees that all receiving and expensedelivery of goods and merchandise and all removal of merchandise, promptly comply with all Legal Requirements now in force supplies, equipment, trash and garbage shall be made only by way of the south rear entrance of the Building. (j) Tenant shall not place, or which may hereafter permit to be in force and with the requirements of placed, any board of fire underwriters merchandise or other similar body now or hereafter constituted relating to or affecting obstruction on the use or occupancy of all sidewalks immediately adjoining the Premises. (k) Tenant shall not go upon the roof of the Premises, excluding such structural changes as Building or permit anyone else to do so without Landlord's prior approval except for maintenance of equipment. (1) Tenant shall not relate to obstruct the Common Area and/or store anything in the Common Area or affect outside the use or occupancy of the Premises, or as are not related to or afforded Building except for space expressly designated by Tenant’s improvements or actsLandlord for storage.

Prohibited Uses. (a) Notwithstanding any other provision of this Lease, Tenant will shall not useuse the Premises or the Building, occupy or any part thereof, or suffer or permit the use or occupancy of the Premises or the Building or any part thereof by any of the Premises Tenant Parties (hereinafter defined) (i) in a manner which would violate any of the covenants, agreements, terms, provisions and conditions of this Lease or otherwise applicable to or binding upon the Premises; (ii) in a manner which, in the reasonable judgment of Landlord (taking into account the Building for office use and the Permitted Uses) shall (a) impair the appearance or reputation of the Building; (b) impair, interfere with or otherwise diminish the quality of any purpose of the Building services or the proper and economic heating, cleaning, ventilating, air conditioning or other servicing of the Building or Premises, or the use of any of the Common Areas; (c) occasion discomfort, inconvenience or annoyance in any material respect, or cause any injury or damage to any occupants of the Premises or other tenants or occupants of the Building or their property; or (d) cause harmful air emissions or any unusual or other objectionable odors, noises or emissions to emanate from the Premises; (iii) in a manner which is shall increase such insurance rates on the Building or may be, directly on property located therein over that applicable when Tenant first took occupancy of the Premises hereunder; or indirectly, (vii) in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of exclusive use granted to any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record other tenant in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirementsBuilding. (b) With respect to the use and occupancy of the Premises and the Common Areas, Tenant shall not keep will not: (i) place or maintain any signage (except as may be permitted by Article 10 below), Trash (hereinafter defined) or other articles in any vestibule or entry of the Premises, on the footwalks or corridors adjacent thereto or elsewhere on the exterior of the Premises, nor obstruct any driveway, corridor, footwalk, parking area, mall or any other Common Areas; (ii) permit undue accumulations of or burn garbage, trash, rubbish or other refuse (collectively, “Trash”) within or outside of the Premises; (iii) permit the parking of vehicles so as to be kept interfere with the use of any substance indriveway, corridor, footwalk, parking area, or other Common Areas; (iv) receive or ship articles of any kind outside of those areas reasonably designated by Landlord; (v) conduct or permit to be conducted any operation fromauction, going out of business sale, bankruptcy sale (unless directed by court order), or other similar type sale in or connected with the Premises; (vi) use the name of Landlord, or any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors Landlord’s affiliates or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings subsidiaries in any way. publicity, promotion, press release, advertising, printed, electronic or display materials without Landlord’s prior written consent (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenantwithheld in Landlord’s sole cost and expensediscretion); (vii) permit any animals other than service animals in the Building; or (viii) except in connection with Alterations (hereinafter defined) approved by Landlord, promptly comply with all Legal Requirements now cause or permit any hole to be drilled or made in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all part of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or actsBuilding.

Prohibited Uses. (a) Tenant will not use, occupy or permit the use or occupancy of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant Tenant's agents shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit suffer to be committed any action waste upon the Premises. Tenant and Tenant's agents shall not do or circumstance permit anything to be done in or about the Premises or Common Area which will in any way obstruct or interfere with the rights of any authorized users of the Common Area or occupants of neighboring property, or injure or annoy them. Tenant shall not conduct or permit any auction or sale open to the public to be held or conducted on or about the Premises or Common Area. Tenant and Tenant's agents shall not use or allow the Premises to be used for any unlawful, immoral or hazardous purpose or any purpose not permitted by this Lease, nor shall Tenant or Tenant's agents cause, maintain, or permit any nuisance in, on or about the Premises, . Tenant and Tenant's agents shall not do or permit anything to be done in or about the Premises or Common Area nor bring or keep anything therein whichin the Premises or Common Area which will in any way increase the rate of any insurance upon the Premises or Common Area or any part thereof or any of its contents, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premisesthe Premises or Common Area or any part thereof or any of its contents, nor shall Tenant or Tenant's agents keep, use or sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with insurance. In the requirements event the rate of any board insurance upon the Premises or Common Area or any part thereof or any of fire underwriters its contents is increased because of Tenant's particular use of the Premises or that of Tenant's agents, Tenant shall pay, as Additional Rent, the full cost of such increase; provided however this provision shall in no event be deemed to constitute a waiver of Landlord's right to declare a default hereunder by reason of the act or conduct of Tenant or Tenant's agents causing such increase or of any other similar body now rights or hereafter constituted relating to remedies of Landlord in connection therewith. Tenant and Tenant's agents shall not place any loads upon the floor, walls or affecting ceiling of the use Premises which would endanger the Premises or occupancy of all the structural elements thereof, nor place any harmful liquids in the drainage system of the Premises, excluding such structural changes as do not relate . No waste materials or refuse shall be dumped upon or permitted to or affect the use or occupancy remain upon any part of the PremisesPremises or Common Area except in enclosed trash containers designated for that purpose by Landlord. No materials, supplies, equipment, finished products (or as are not related to or afforded by Tenant’s improvements or acts.semi-finished products), raw

Prohibited Uses. (a) Tenant will agrees that neither Tenant nor any subtenant, assignee or occupant of the Demised Premises shall at any time during the term of this lease occupy or use the Demised Premises or permit the same to be used or occupied in any manner except as provided in Section 9.01. The following non-exclusive list of uses shall not be deemed to be "executive, administrative, accounting and general office purposes", and Tenant shall not use, occupy or permit the use of, the Demised Premises or any part thereof, for: (i) the conduct of a public auction of any kind, or of any gaming or gambling activities, or for any political or club activities, whether public or private; (ii) the conduct of a school of any kind or as an employment agency; (iii) the sale, at retail or wholesale, of any products or materials kept in the Demised Premises, by vending machine or otherwise; (iv) manufacturing purposes; (v) the rendition to the public of medical, dental or other diagnostic or therapeutic services; (vi) a restaurant, bar, or the sale of confectionery, tobacco, newspapers, magazines, soda, beverages, sandwiches, ice cream, baked goods or similar items, or the preparation, dispensing or consumption of food and beverages; (vii) the conduct of any business, occupation or activity which, in Landlord's reasonable judgment may (x) impair the reputation of the Buildings, (y) interfere with or disturb the occupancy of other tenants or occupants of the Buildings, or (z) create or fost▇▇ ▇▇ unusual risk to the security of the Buildings or of any of their tenants or occupants; (viii) the conduct of any business not engaged in by Tenant at the date of this lease, if the use of the Demised Premises for such business shall conflict with any purpose or negative covenants as to use contained in any manner which is or may be, directly or indirectly, in violation other lease of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record space in the office Buildings entered into subsequent to the date of this lease but prior to the use of the county recorder Demised Premises for such other business, provided that Landlord shall have notified Tenant of the county in which existence of such Premises are located on negative covenants; or before 18 (ix) printing and reproduction of materials for sale or for the date on which such Premises became subject purpose of rendering services to this Lease, or (iii) insurance requirementsothers. (b) Tenant shall not keep suffer or permit the Demised Premises or any part thereof to be used in any manner, or anything to be done therein, or suffer or permit anything to be brought into or kept in the Demised Premises, which would in any substance way (i) violate any laws or requirements of public authorities (subject to the right to contest such laws or requirements as provided in, and subject to the provisions of, Section 14.02), (ii) cause injury to the Buildings or conduct any part thereof, (iii) constitute a public or permit private nuisance, (iv) impair the appearance of the exterior of the Buildings, (v) impair the use for normal purposes of any other area of the Buildings by (or occasion physical discomfort to, or interfere with services required to be conducted any operation from, furnished by Landlord to Tenant or to) any of the Premises which is not reasonably consistent with other tenants and occupants of the Permitted Use for such Premises and which might emit offensive odors or conditionsBuildings, or make undue noise or create undue vibrations(vi) violate any of Tenant's other obligations under this lease. (c) Tenant shall not commit cause (or permit to remain any waste to allow any of its contractors, agents or other persons or entities over whom or which it exercises a degree of control to cause) to occur within the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Demised Premises, or adversely affect the mechanicalBuildings, plumbing any discharge, spillage, uncontrolled loss, seepage or electrical systems filtration of any such buildingshazardous waste or oil or petroleum liquids or solids, asbestos, pcb, radioactive substances, methane, volatile hydrocarbons, industrial solvents, or affect any other materials or substances which have in the structural integrity of any such buildings in any way. (e) Tenant shall not commit past caused or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premisesconstituted, or as are not related in the future found to cause or afforded by Tenant’s improvements constitute, a health, safety or actsenvironmental hazard.

Prohibited Uses. (a) Tenant will not use, occupy or permit The Licensee shall use reasonable efforts to ensure that the Authorised Users are aware of the prohibitions on the use or occupancy of the Licensed Materials set out in this Licence and the Licensee shall use reasonable endeavours to ensure that its Authorised Users do not breach the prohibitions set out in this Licence in respect of their access to and use of the Licensed Materials. The Licensee shall be liable for any breach by Authorised Users of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation provisions of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premisesthis Licence, including but not limited to zoning, environmental the provisions set out below. b) Authorised Users may not: i) Remove or alter the author’s name(s) or the publisher’s copyright notices or other means of identification or any and utility conservation matters (hereinafter “Legal Requirements”), (all disclaimers as they appear in the Licensed Materials; ii) covenantsSystematically make print or electronic copies of multiple extracts or make multiple copies of any part of the Licensed Materials for any purpose other than that permitted by this Licence; iii) Prepare derivative works or download, conditionsmount or distribute any part of the Licensed Material on any electronic system or network, including without limitation the Internet and the World Wide Web, other than by the Licensee's Secure Network approved in advance by The Company of Biologists, except where expressly permitted under this Licence; iv) Sell or resell the Licensed Materials unless The Company of Biologists has given prior written permission for the Authorised User to do so; v) Alter, edit, abridge or otherwise modify the Licensed Materials or any part of them for any purpose whatsoever or incorporate any part of any Licensed Materials (whether in amended or unamended form) into any other work; vi) Make any Commercial Use of the Licensed Material (in whole or in part); or vii) provide access to and/or permit use of the Licensed Content by anyone, or restrictions applicable to such Premises and appearing of record in the office transmit any part of the county recorder Licensed Material (other than Metadata) by any means to anyone, other than an Authorised User, except as otherwise may be permitted under Appendix B (including by way of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirementsinter-library lending). (bc) Tenant shall not keep The Licensee must seek and obtain The Company of Biologists’ permission prior to carrying out or permit attempting to be kept any substance in, or conduct or permit to be conducted any operation from, carry out any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrationsforegoing uses. Email ▇▇▇▇▇▇▇▇▇▇▇@▇▇▇▇▇▇▇▇▇▇.▇▇▇. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant This clause 4 shall not install or permit continue to remain apply after termination of this Licence for any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any wayreason. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.

Prohibited Uses. (a) Tenant will not use, occupy or permit the use or occupancy of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant Tenant's agents shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit suffer to be committed any action waste upon the Premises. Tenant and Tenant's agents shall not do or circumstance permit anything to be done in or about the Premises or Parking Area which will in any way obstruct or interfere with the rights of Landlord, or injure or annoy Landlord or its employees. Tenant and Tenant's agents shall not use or allow the Premises to be used for any unlawful, immoral or any purpose not permitted by this Lease, nor shall Tenant or Tenant's agents cause, maintain, or permit any nuisance in, on or about the Premises, . Tenant and Tenant's agents shall not do or permit anything to be done in or about the Premises or Parking Area nor bring or keep anything therein whichin the Premises or Parking Area which will in any way increase the rate of any insurance upon the Premises or Parking Area or any part thereof or any of its contents, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premisesthe Premises or Parking Area or any part thereof or any of its contents, nor shall Tenant or Tenant's agents keep, use or sell or permit to be kept, used or sold in or about any of the Premises or Parking Area any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with insurance. In the requirements event the rate of any board insurance upon the Premises or Parking Area or any part thereof or any of fire underwriters its contents is increased because of the acts or omissions of Tenant or Tenant's agents, Tenant shall pay, as Additional Rent, the full cost of such increase; provided however this provision shall in no event be deemed to constitute a waiver of Landlord's right to declare a Default hereunder by reason of such increase or of any other similar body now rights or hereafter constituted relating to remedies of Landlord in connection with such increase. Tenant and Tenant's agents shall not place any loads upon the floor, walls, or affecting ceiling of the use Premises which would endanger the Premises or occupancy of all the structural elements thereof, nor place any harmful liquids in the drainage system of the Premises. No waste materials or refuse shall be dumped upon or permitted to remain upon any part of the Premises or Parking Area except in enclosed trash containers. No materials, excluding such structural changes supplies, equipment, finished products (or semi-finished products), raw materials, or other articles of any nature shall be stored upon, or be permitted to remain on, any portion of the Parking Area. Tenant shall not use, store on, dispose or allow the use, storage or disposal, of any Hazardous Materials, as do not relate to or affect the use or occupancy that term is defined in Section 24.2, on any portion of the Premises. Tenant shall indemnify, and hold Landlord, and its officers, directors, employees and agents harmless from and against any and all claims, losses, damages, liabilities or as are not related expenses (including, without limitation, attorneys' fees) arising in connection with a breach of the obligations set forth herein. Tenant's obligation to defend, hold harmless and indemnify pursuant to this Section shall survive Lease Termination or afforded by Tenant’s improvements or actsexpiration.

Prohibited Uses. (a) Tenant will Throughout the Term, Landlord shall not usefurther develop the Property, occupy or permit other than consistent with the use or occupancy provisions of any this Lease, and, without limiting the generality thereof, no such further development shall be permitted if (1) the same would cause a violation of the Premises for any purpose provisions of Section 4.8(b) hereof or Section 14.20 hereof, or (2) the same would otherwise result in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances an increase in the amount of any governmental authority in any way applicable to Additional Rent payable by Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”)hereunder, (ii) covenantsany other cost or expense being imposed upon Tenant or any Tenant Party, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirementsany reduction in the value of the Leased Premises to Tenant or any Tenant Party, (iv) parking or traffic flow on the Property being adversely affected from the perspective of Tenant or any Tenant Party, (v) any reduction in the function or utility of the Common Areas (or any portion thereof) from the perspective of Tenant or any Tenant Party. (b) Tenant Throughout the Term, Landlord shall not keep use, or permit the use of, the Property (or any part thereof) for any Prohibited Uses. The term “Prohibited Uses” shall mean (i) any use that emits an obnoxious odor, noise or sound that can be heard or smelled outside of the premises; (ii) any use in violation of zoning regulations or any other governmental restrictions applicable to the Property; (iii) any use that, by its nature, (even if such use is legally permissible) would result in parking or traffic flow on the Property being materially adversely affected from the perspective of Tenant or any Tenant Party; (iv) any operation primarily used as a warehouse or storage facility, assembling or manufacturing, distilling, refining, rendering, processing, smelting, agricultural or mining operations; (v) any mobile home park or sales, trailer court, labor camp, junk yard or stockyard; (vi) any central laundry, dry cleaning plant or laundromat; provided, however, this prohibition shall not be kept applicable to on-site services oriented only to pickup and delivery by consumers; (vii) any substance inautomobile, truck, trailer or recreational vehicle sales, leasing, display, repair or body shop; (viii) any living quarters, sleeping apartments, hotel or lodging rooms; (xi) veterinary hospitals, animal raising or breeding facilities, animal boarding facilities or pet shops; (x) mortuaries or funeral homes; (xi) any establishment that sells, rents or exhibits pornographic materials; (xii) massage parlors or any form of sexually oriented business (including novelty merchandise sales); (xiii) bars, taverns or brew pubs; (xiv) flea markets, amusement or video arcades, computer game rooms, pool or billiard halls, bingo halls, dance halls, discos or night clubs; (xv) sales of paraphernalia for use with illicit drugs; (xvi) carnivals, amusement parks or circuses; (xvii) pawn shops, auction houses, second hand stores, consignment shops, army/navy surplus stores or gun shops; (xviii) gambling facilities or sports betting parlor; (xix) churches, synagogues or other places of worship; (xx) assembly halls or meeting facilities; (xxi) technical or vocational schools or any other operation primarily engaged in education or training activities; (xxii) medical clinics, abortion clinics, medical laboratories or screening facilities; (xxiii) any agency (public or private) providing health, welfare, social or human services, or conduct (xxiv) tattoo parlors, fortune telling or permit to be conducted spiritual readings; (xxv) facilities that collect donated goods and products; (xxvi) bowling alleys, skating rinks, archery or gun ranges, (xxvii) postal facilities, tax collectors, tag agencies, jails or detention centers, courthouses or any operation fromother form of agency dealing with civil authority. Notwithstanding the foregoing, the term “Prohibited Uses” shall not include any use which is permitted under a third party tenant lease of space in the Building which is in effect as of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrationsCommencement Date. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.

Prohibited Uses. (a) Tenant will shall not usecause, occupy suffer or permit the Premises or any part thereof to be used at any time during the Term for any of the following sales, businesses or activities: (i) any retail or wholesale sales activities; (ii) any auction; (iii) any vending machines or other coin operated machines, entertainment or games machines or any other mechanical or electrical serving or dispensing machines or devices whatsoever or the sale or supply of food or beverages (other than food or beverages such as are routinely served in office premises without charge to employees such as coffee and soft drinks) unless expressly permitted in writing by Landlord, in its sole discretion; (iv) any sale of tickets for theatre or other entertainment events or lottery tickets; (v) any business which would result in people waiting in Common Facilities to enter the Premises; (vi) any type of business or business practice which would, in the sole opinion of Landlord, tend to lower the character or image of the Project or any portion thereof; (vii) any use which in any way contravenes any restrictive covenants in leases granted by Landlord; Tenant covenants and agrees that it will not carry on in the Premises any business which will in any way place Landlord in breach of any such restrictive covenants and Tenant will indemnify and save Landlord harmless from and against all actions, claims, demands and costs with respect thereto; this subsection (vii) shall not be interpreted to prevent Tenant from carrying on in the Premises any business to the extent expressly permitted pursuant to section 8.1 hereof; or (viii) any business or occupancy activity not in compliance with all Laws, The inclusion of the foregoing provisions of this section 8.5 shall not be deemed to be a representation or warranty of Landlord that any of the foregoing activities will not be authorized by Landlord to be conducted on any part of the Project. Tenant shall forthwith, upon the request of Landlord, discontinue any business, conduct or practice carried on or maintained in or about the Premises, which, in Landlord’s sole opinion, may damage or reflect unfavourably upon Landlord, the Project, or any other tenants or occupants thereof. If, in the opinion of Landlord, Tenant is in breach of any of the Premises for any purpose or in any manner which is or may beprovisions of this section 8.5, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for immediately discontinue such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrationsuse upon Landlord’s written request. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.

Prohibited Uses. (a) Tenant will shall not use, occupy or suffer or permit the use --------------- of. or occupancy suffer or permit anything to be done in or anything to be brought into or kept in, the Demised Premises or any part thereof (i) which would violate any of the covenants, agreements, terms, provisions and conditions of this Lease, (ii) for any unlawful purposes or in any unlawful manner. or (iii) which, in the reasonable judgment of Landlord shall in any way (a) impair or tend to impair the appearance or reputation of the Building, (b) impair or interfere with or tend to impair or interfere with any of the Building services or the proper and economic heating, cleaning, air conditioning or other servicing of the Building or Demised Premises, or with the use of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office other areas of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this LeaseBuilding, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit occasion discomfort, inconvenience or permit to remain any waste annoyance to any of the Premises. (d) Tenant shall not install other tenants or permit to remain any improvements to any occupants of the Premises which exceed Building, whether through the structural loads transmission of floors noise or walls odors or otherwise. Without limiting the generality of any buildings located the foregoing, no food shall be prepared or served for consumption on or about the Demised Premises; no intoxicating liquors or alcoholic beverages shall be sold on or about the Demised Premises; no lottery tickets (even where the sale of such tickets is not illegal) shall be sold and no gambling, betting or wagering shall otherwise be permitted oil or about the Demised Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant ; no loitering shall not commit or permit to be committed any action or circumstance permitted in or about any the Demised Premises; and no loading or unloading of supplies or other material to or from the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor Demised Premises shall Tenant sell or permit be permitted on the Land except at times and in locations to be keptdesignated by Landlord. The Demised Premises shall be maintained in a sanitary condition, used or sold and all kept free of rodents and vermin. All trash and rubbish shall be suitably stored in or about any of the Demised Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating locations designated by Landlord from time to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or actstime.

Prohibited Uses. (a) Tenant will further covenants and agrees that Tenant shall not use, occupy or suffer or permit any person or persons to use, the Premises or any part thereof for any use or occupancy purpose contrary to the provisions of the Rules and Regulations set forth in Exhibit E, attached hereto and incorporated herein by this reference, as the same may be amended from time to time (the “Rules and Regulations”), or in violation of any Underlying Documents or Applicable Laws, including, without limitation, any such laws, ordinances, regulations or requirements relating to hazardous materials or substances, as those terms are defined by Applicable Laws now or hereafter in effect. Tenant shall not do or permit anything to be done in or about the Premises which will damage the reputation of the Project or obstruct or interfere with the rights of other tenants or occupants of the Project, or injure or annoy them or use or allow the Premises to be used for any improper, unlawful or objectionable purpose, nor shall Tenant cause, maintain or permit any nuisance in, on or about the Premises. Tenant shall not suffer or allow any offensive or obnoxious vibration, noise, odor or other undesirable effect to emanate from the Premises, or any machine or other installation therein, or otherwise suffer or allow the same to constitute a disturbance to other tenants or occupants of the Building (acknowledging that Tenant may be using the Premises in a manner that is different from other tenants or occupants of the Building and that Tenant’s use of the Premises for any purpose the Permitted Use will not be deemed to constitute a disturbance to such other tenants or occupants so long as Tenant is using the Premises in any a manner which is reasonably similar to other similarly situated life science or may be, directly biotech companies involved in light manufacturing in similarly situated buildings or indirectlydevelopments, in violation accordance with the terms of any (i) judicial decisionsthis Lease, ordertakes appropriate measures in its design of the Premises to ensure that its operations will not unreasonably disturb other tenants or occupants, injunctionsand otherwise uses commercially reasonable efforts not to disturb such other tenants or occupants of the Building). Tenant shall comply with, writsand T▇▇▇▇▇’s rights and obligations under this Lease and T▇▇▇▇▇’s use of the Premises shall be subject and subordinate to, statutesall recorded easements, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, and restrictions now or restrictions applicable to such Premises hereafter affecting the Project. Additionally, Tenant shall cooperate fully with Landlord at all times and appearing abide by all regulations and requirements that Landlord may reasonably prescribe for the proper functioning and protection of record the HVAC, electrical, mechanical and plumbing systems. Notwithstanding the foregoing, in the office event of any conflict between any Rules and Regulations and the county recorder express terms of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or the terms of this Lease shall control. Landlord shall provide reasonable advance written notice of any changes to the Rules and Regulations, and Landlord shall not institute any changes to the Rules and Regulations that (iiia) insurance requirements. unreasonably and materially prohibit Tenant from using the Premises for the Permitted Use, (b) Tenant shall directly by its terms requires payment of an additional material sum of money, and (c) are not keep or permit uniformly applicable to be kept any substance in, or conduct or permit to be conducted any operation from, any of the tenants in the Building using the Premises which is not reasonably in a manner consistent with the Permitted Use for (provided that such Premises and which might emit offensive odors changes may affect Tenant or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any other tenants in different ways based on their use of the Premisespremises or rights granted to Tenant or such other tenant(s), and further provided that Landlord shall have the right to waive a rule or regulation for the benefit of a particular tenant or tenants). (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.

Prohibited Uses. (a) Tenant will Throughout the Term, Landlord shall not usefurther develop the Property, occupy or permit other than consistent with the use or occupancy provisions of any this Lease, and, without limiting the generality thereof, no such further development shall be permitted if (1) the same would cause a violation of the Premises for any purpose provisions of Section 4.8(b) hereof or Section 14.20 hereof, or (2) the same would otherwise result in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances an increase in the amount of any governmental authority in any way applicable to Additional Rent payable by Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”)hereunder, (ii) covenantsany other cost or expense being imposed upon Tenant or any Tenant Party, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirementsany reduction in the value of the Leased Premises to Tenant or any Tenant Party, (iv) parking or traffic flow on the Property being adversely affected from the perspective of Tenant or any Tenant Party, (v) any reduction in the function or utility of the Common Areas (or any portion thereof) from the perspective of Tenant or any Tenant Party. (b) Tenant Throughout the Term, Landlord shall not keep use, or permit the use of, the Property (or any part thereof) for any Prohibited Uses. The term “Prohibited Uses” shall mean (i) any use that emits an obnoxious odor, noise or sound that can be heard or smelled outside of the premises; (ii) any use in violation of zoning regulations or any other governmental restrictions applicable to the Property; (iii) any use that, by its nature, (even if such use is legally permissible) would result in parking or traffic flow on the Property being materially adversely affected from the perspective of Tenant or any Tenant Party; (iv) any operation primarily used as a warehouse or storage facility, assembling or manufacturing, distilling, refining, rendering, processing, smelting, agricultural or mining operations; (v) any mobile home park or sales, trailer court, labor camp, junk yard or stockyard; (vi) any central laundry, dry cleaning plant or laundromat; provided, however, this prohibition shall not be kept applicable to on-site services oriented only to pickup and delivery by consumers; (vii) any substance inautomobile, truck, trailer or recreational vehicle sales, leasing, display, repair or body shop; (viii) any living quarters, sleeping apartments, hotel or lodging rooms; (xi) veterinary hospitals, animal raising or breeding facilities, animal boarding facilities or pet shops; (x) mortuaries or funeral homes; (xi) any establishment that sells, rents or exhibits pornographic materials; (xii) massage parlors or any form of sexually oriented business (including novelty merchandise sales); (xiii) bars, taverns or brew pubs; (xiv) flea markets, amusement or video arcades, computer game rooms, pool or billiard halls, bingo halls, dance halls, discos or night clubs; (xv) sales of paraphernalia for use with illicit drugs; (xvi) carnivals, amusement parks or circuses; (xvii) pawn shops, auction houses, second hand stores, consignment shops, army/navy surplus stores or gun shops; (xviii) gambling facilities or sports betting parlor; (xix) churches, synagogues or other places of worship; (xx) assembly halls or meeting facilities; (xxi) technical or vocational schools or any other operation primarily engaged in education or training activities; (xxii) medical clinics, abortion clinics, medical laboratories or screening facilities; (xxiii) any agency (public or private) providing health, welfare, social or human services, or conduct (xxiv) tattoo parlors, fortune telling or permit to be conducted spiritual readings; (xxv) facilities that collect donated goods and products; (xxvi) bowling alleys, skating rinks, archery or gun ranges, (xxvii) postal facilities, tax collectors, tag agencies, jails or detention centers, courthouses or any operation fromother form of agency dealing with civil authority. Notwithstanding the foregoing, the term "Prohibited Uses" shall not include any use which is permitted under a third party tenant lease of space in the Building which is in effect as of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrationsCommencement Date. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.

Prohibited Uses. Tenant shall keep the Premises free from waste and nuisance at all times. Tenant shall keep the Premises clean throughout, (aincluding, but without limitation, floors, light fixtures and all glass). Tenant shall not, without Landlord's prior consent, locate or install or cause to be located or installed on the sidewalks or service area (if any) Tenant will not useimmediately adjoining the Premises any bike racks, occupy or permit the use or occupancy newspaper holder stands, vending machines of any kind, mailboxes, telephone booths, “No parking” signs or any other device of a similar nature which would impede or obstruct the sidewalk or service area. Tenant shall not, without ▇▇▇▇▇▇▇▇'s prior written consent, perform or fail to perform any act, keep anything within the Premises, or use the Premises for any purpose which increases the insurance premium cost or in invalidates any manner which is insurance policy carried on either the Premises or may beon other parts of the center. If Landlord does give such written consent to Tenant, directly or indirectlythen Tenant shall be responsible, in violation at its sole cost and expense for the amount of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record increase in the office of the county recorder of the county in which such Premises are located on casualty or before the date on which such Premises became subject to this Lease, or (iii) liability insurance requirements. (b) premium cost. Tenant shall not keep or permit to be kept any substance innot, or without ▇▇▇▇▇▇▇▇'s prior written consent, conduct or permit to be conducted any operation from, any of within the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive any auction or bankruptcy sales nor permit any objectionable or unpleasant odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit loud noises to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of emanate from the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell place or permit to any radio, television or other antennae, loud speaker or amplifiers, or flashing lights or searchlights on the roof or outside the Premises or where the same can be kept, used seen or sold in heard outside the building; nor take any other action which would disturb or about any endanger other Tenants of the Premises any articles which may be prohibited by a standard form policy Center (if applicable) or unreasonably interfere with their use of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articlestheir respective premises or the Common Area. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.

Prohibited Uses. (a) Notwithstanding any other provision of this Lease, Tenant will shall not useuse the Premises or the Building, occupy or any part thereof, or suffer or permit the use or occupancy of the Premises or the Building or any part thereof by any of the Tenant Parties (i) in a manner which would violate any of the covenants, agreements, terms, provisions and conditions of this Lease or otherwise applicable to or binding upon the Premises; (ii) for any unlawful purposes or in any unlawful manner; (iii) which, in the reasonable judgment of Landlord (taking into account the use of the Building as a combination laboratory, research and development and office building and the Permitted Uses) shall (a) impair the appearance or reputation of the Building; (b) impair, interfere with or otherwise diminish the quality of any of the Building services or the proper and economic heating, cleaning, ventilating, air conditioning or other servicing of the Building or Premises, or the use or occupancy of any of the Premises for any purpose Common Areas; (c) occasion discomfort, inconvenience or annoyance in any material respect (and Tenant shall not install or use any electrical or other equipment of any kind (including, without limitation, Tenant’s Rooftop Equipment) which, in the reasonable judgment of Landlord, will cause any such impairment, interference, discomfort, inconvenience, annoyance or injury), or cause any injury or damage to any occupants of the Premises or other tenants or occupants of the Building or their property; or (d) cause harmful air emissions, laboratory odors or noises or any unusual or other objectionable odors, noises or emissions to emanate from the Premises; (iv) in a manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or inconsistent with the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office operation and/or maintenance of the county recorder Building as a first-class combination office, research, development and laboratory facility; or (v) in a manner which shall increase such insurance rates on the Building or on property located therein over that applicable when Tenant first took occupancy of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirementshereunder. (b) Tenant shall not keep or permit With respect to be kept any substance in, or conduct or permit to be conducted any operation from, any the use and occupancy of the Premises which is not reasonably consistent with and the Permitted Use for such Premises and which might emit offensive odors Common Areas, Tenant will not: (i) place or conditionsmaintain any signage (except as set forth in Section 12.2 below), trash, refuse or make undue noise other articles in any vestibule or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any entry of the Premises. (d) Tenant shall not install , on the footwalks or permit to remain any improvements to any of corridors adjacent thereto or elsewhere on the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any exterior of the Premises, nor bring obstruct any driveway, corridor, footwalk, parking area, mall or keep anything therein whichany other Common Areas; (ii) permit undue accumulations of or burn garbage, directly or indirectlytrash, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters rubbish or other similar body now refuse within or hereafter constituted relating to or affecting the use or occupancy of all of without the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.;

Prohibited Uses. (a) Tenant will shall not use, occupy or suffer or permit the use of, or occupancy of suffer or permit anything to be done in or anything to be brought into or kept in, the Demised Premises or any part thereof (i) which would violate any of the Premises for any purpose or in any manner which is or may becovenants, directly or indirectlyagreements, in violation terms, provisions and conditions of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”)this Lease, (ii) covenants, conditions, for any unlawful purposes or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Leaseany unlawful manner, or (iii) insurance requirements. which, in the reasonable judgment of Landlord shall in any way (a) impair or tend to impair the appearance or reputation of the Building, (b) Tenant shall not keep impair or permit interfere with or tend to be kept any substance in, impair or conduct or permit to be conducted any operation from, interfere with any of the Premises which is not reasonably consistent Building services or the proper and economic heating, cleaning, air conditioning or other servicing of the Building or with the Permitted Use for such Premises and which might emit offensive odors or conditionsuse of any of the other areas of the Building, or make undue noise or create undue vibrations. (c) Tenant shall not commit occasion discomfort, inconvenience or permit to remain any waste annoyance to any of the other tenants or occupants of the Building, whether through the transmission of noise or odors or vibrations or dust or otherwise. Without limiting the generality of the foregoing, no food shall be prepared or served for consumption by the general public on or about the Demised Premises; no intoxicating liquors or alcoholic beverages shall be sold or otherwise served for consumption by the general public on or about the Demised Premises; no lottery tickets (even where the sale of such tickets is not illegal) shall be sold and no gambling, betting or wagering shall otherwise be permitted on or about the Demised Premises; no loitering shall be permitted on or about the Demised Premises; and no loading or unloading of supplies or other material to or from the Demised Premises shall be permitted on the Land except at times (excluding Business Days from 7:00 to 9:30 a.m. and from 4:00 to 6:00 p.m.) and in locations to be designated by Landlord. The Demised Premises shall be maintained in a sanitary condition. Tenant shall suitably store all trash and rubbish in the Demised Premises or other locations designated by Landlord from time to time. Tenant specifically agrees that its indemnification obligations pursuant to Section 13.3 shall extend to any claim arising from the consumption of intoxicating liquors or alcoholic beverages on or about the Demised Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.

Prohibited Uses. (a) Tenant will further covenants and agrees that Tenant shall not use, occupy or suffer or permit any person or persons to use, the Premises or any part thereof for any use or occupancy purpose contrary to the provisions of the Rules and Regulations set forth in Exhibit A, attached hereto, or in violation of the laws of the United States of America, the State of California, the ordinances, regulations or requirements of the local municipal or county governing body or other lawful authorities having jurisdiction over the Project) including, without limitation, any such laws, ordinances, regulations or requirements relating to hazardous materials or substances, as those terms are defined by applicable laws now or hereafter in effect, or any easement, license, operating agreement, declaration, restrictive covenant, or instrument recorded against the Project, including, without limitation, any covenants, conditions and restrictions affecting the Project, any reciprocal easement agreements affecting the Project, any parking licenses, and any agreements with transit agencies affecting the Project (collectively, "Underlying Documents"). A violation of the Rules and Regulations by Tenant shall be deemed a default under this Article 5. Tenant shall not do or permit anything to be done in or about the Premises which will in any way damage the reputation of the Project or obstruct or interfere with the rights of other tenants or occupants of the Building, or injure or annoy them or use or allow the Premises to be used for any improper, unlawful or objectionable purpose, nor shall Tenant cause, maintain or permit any nuisance in, on or about the Premises. Tenant shall comply with, and Tenant's rights and obligations under the Lease and Tenant's use of the Premises shall be subject and subordinate to, all recorded easements, covenants, conditions, and restrictions now or hereafter affecting the Project so long as any such recorded easements, covenants, conditions, and restrictions first affecting the Project after the date of this Lease do not materially adversely affect Tenant’s possession, use or enjoyment of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or materially adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or actsparking rights under this Lease.

Prohibited Uses. (a) Tenant will shall not usecause, occupy suffer or permit the Premises or any part thereof to be used at any time during the Term for any of the following sales, businesses or activities: (i) any retail or wholesale sales activities; (ii) any auction; (iii) any vending machines or other coin operated machines, entertainment or games machines or any other mechanical or electrical serving or dispensing machines or devices whatsoever or the sale or supply of food or beverages to the general public (which for clarity excludes the sale or supply of food or beverages such as are routinely served in office premises) unless expressly permitted in writing by Landlord, acting reasonably. Notwithstanding the foregoing, Tenant shall be permitted to have up to two (2) food and beverage vending machines for use by Tenant’s employees; (iv) any sale of tickets for theatre or occupancy other entertainment events or lottery tickets; (v) any use which would result in people waiting in Common Facilities to enter the Premises or any other type of business or business practice which would, in the sole opinion of Landlord, acting reasonably, tend to lower the character or image of the Project or any portion thereof; (vi) a call centre; (vii) a use which will be incompatible with the uses of other tenants of the Project, in the sole discretion of Landlord, acting reasonably (provided that the foregoing shall not prohibit the Tenant from carrying out the permitted use expressly set out under subsection 1(i) of this Lease), or will be more burdensome on the Project, in terms of parking requirements or any other factor, than the permitted use of the Premises by Tenant; (viii) any use which will result in a breach of any of the Premises for any purpose other provisions of this Lease; (ix) a school or in any manner which is or may be, directly or indirectly, in violation training centre of any kind; or (ix) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates any use which will: (I) result in an actual or ordinances threatened cancellation of any governmental authority policy of insurance of Landlord or others on or related to the Project or any part or contents thereof; or (II) be prohibited by any policy of insurance of Landlord or any others in any way applicable force from time to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record time in the office respect of the county recorder Project or any part or contents thereof. The inclusion of the county in which such Premises are located foregoing provisions of this Section 8.5 shall not be deemed to be a covenant, representation or warranty of Landlord that any of the foregoing activities will not be authorized by Landlord to be conducted on or before any part of the date on which such Premises became subject to this Lease, or (iii) insurance requirementsProject. (b) Notwithstanding anything contained in the foregoing to the contrary, so long as the Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any in actual physical occupancy of substantially the whole of the Premises for the active and diligent conduct of business therefrom is Primerica Life Insurance Company of Canada and/or a Permitted Transferee, the use of portions of the Premises for handling telephone inquiries and communications between, among and regarding employees, clients, agents or prospective clients or agents and/or for the internal training of employees, clients, agents or prospective clients or agents, shall not constitute a breach of the provisions of subsections 8.5(a)(vi) and 8.5(a)(ix) above provided that: (i) the live load for the floor of the Premises upon which is such activities are being conducted does not reasonably consistent exceed 100 lbs. (75 live, ▇▇ ▇▇▇▇) ▇▇▇ ▇▇▇▇▇▇ ▇▇▇▇; (▇▇) in Landlord’s determination, acting reasonably, such activities do not overburden the Common Facilities (including the Parking Facilities ) or base Building systems serving the Premises; and (iii) Tenant shall be responsible for any Excess Costs which result from such activities in accordance with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrationsapplicable provisions of this Lease. (c) Tenant shall not commit or permit to remain any waste to any For greater certainty, Landlord acknowledges that Tenant’s use of portions of the PremisesPremises for handling telephone inquiries and communications between, among and regarding employees, clients, agents or prospective clients or agents and/or for the internal training of employees, clients, agents or prospective clients or agents as conducted within the Premises as at the date hereof, i.e. for minor call centre and training purposes, is in accordance with the provisions of this Section 8.5 and does not breach the provisions hereof. (d) Tenant shall not install or permit Landlord hereby acknowledges to remain any improvements to any the best of its information, knowledge and belief, without due inquiry, that the use of the Premises which exceed by Primerica Life Insurance Company of Canada for general business corporate, administrative, sales/marketing, training and support offices will not violate the structural loads provisions of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any waysubsection 8.5(a)(x) above. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.

Prohibited Uses. (a) Tenant will not use, occupy or permit the use or occupancy of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit any Tenant Related Parties to remain commit any waste upon the Premises or Common Area (or any area where Tenant places its Generators or Bloom Boxes to the extent permitted under this Lease). Tenant and Tenant Related Parties shall not do or permit anything to be done in the Premises or do or permit anything to be done by any of them in other parts of the Premises. (d) Building, Project or Common Area which will unreasonably obstruct or interfere with the rights of any other tenants of the Building or Project, other authorized users of the Common Area, or occupants of neighboring property, or injure or unreasonably annoy them. Tenant shall not install conduct or permit any auction or sale open to remain any improvements the public to any of be held or conducted on or about the Premises, Building, Project or Common Area. Tenant and all Tenant Related Parties shall not use or allow the Premises which exceed to be used for any unlawful or hazardous purpose, nor shall Tenant or any Tenant Related Parties cause, maintain, or permit any nuisance in, on or about the structural loads of floors or walls of any buildings located on such Premises, Building, Project or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Common Area. Tenant shall not commit overload existing electrical systems or other mechanical equipment servicing the Building, impair the efficient operation of the sprinkler system or the heating, ventilation or air conditioning equipment within or servicing the Building or Premises or damage, overload or corrode the sanitary sewer system. Tenant and Tenant Related Parties shall not do or permit anything to be committed any action or circumstance done in or about any of the Premises, Premises nor bring or keep anything therein whichin the Premises which will in any way increase the rate of any insurance upon any portion of the Project or any of its contents, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premisesany portion of the Project or any of its contents, nor shall Tenant or any Tenant Related Parties keep, use or sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at upon any portion of the Project or any of its contents is increased because of Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force particular use of the Premises or which may hereafter be in force and with the requirements that of any board Tenant Related Parties, Tenant shall pay, as Additional Rent, the full cost of fire underwriters such increase; provided, however this provision shall in no event be deemed to constitute a waiver of Landlord’s right to declare a default hereunder by reason of the act or conduct of Tenant or any Tenant Related Parties causing such increase or of any other similar body now rights or hereafter constituted relating to remedies of Landlord in connection therewith. Tenant and Tenant Related Parties shall not place any loads upon the floor, walls or affecting ceiling of the use Premises which would endanger the Building or occupancy of all the structural elements thereof or of the Premises, excluding such structural changes as do not relate to or affect nor place any harmful liquids in the use or occupancy drainage system of the PremisesBuilding or Common Area. No waste materials or refuse shall be dumped upon or permitted to remain upon any part of the Project except in enclosed trash containers designated for that purpose by Landlord. Except as expressly permitted by this Lease with respect to Bloom Boxes and Generators (and then subject to the provisions of Paragraphs 48 and 49 below), no materials, supplies, equipment, finished products (or semi-finished products), raw materials, or as are not related other articles of any nature shall be stored upon, or be permitted to or afforded by Tenant’s improvements or actsremain on, any portion of the Project outside the Premises.

Prohibited Uses. Tenant further covenants and agrees that Tenant shall not commit waste, overload the Base Building and Tenant's Building Systems (aas that term is defined in Section 7.2.1 below) Tenant will not or subject the Premises to use that would damage the Premises or use, occupy or suffer or permit any person or persons to use, the Premises or any part thereof for any use or occupancy purpose contrary to the provisions of the Rules and Regulations set forth in Exhibit D, attached hereto (the "Rules and Regulations"), or in violation of any applicable Laws. Tenant's use shall not result in an occupancy density for the Premises which is greater than the density allowed by applicable Laws. No Tenant Party (as that term is defined in Section 10.1 below) shall do or permit anything to be done in or about the Premises or the Project which will in any way damage the reputation of the Project, create extraordinary fire hazards, or result in an increased rate of insurance on the Project or its contents, or obstruct or interfere with the normal and customary use or operation of the Project by Landlord or other tenants and/or occupants (including, without limitation, by means of noise, vibration, odor of other undesirable effect emanating from the Premises or any machine or other installation therein or from any of Tenant's Off-Premises Equipment) or the rights of other tenants or occupants of the Building, or injure or annoy them or use or allow the Premises, Tenant's Building Systems or any of Tenant's Off-Premises Equipment to be used for any improper, unlawful or objectionable purpose, nor shall Tenant cause, maintain or permit any nuisance in, on or about the Premises or the Project. Tenant shall not use any substantial portion of the Premises for a "call center," any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditionsother telemarketing use, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) any credit processing use. Tenant shall not keep or permit to be kept any substance incomply with, or conduct or permit to be conducted any operation from, any and Tenant's rights and obligations under this Lease and Tenant's use of the Premises which is not reasonably consistent with the Permitted Use for such Premises shall be subject and which might emit offensive odors or conditionssubordinate to, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body Underlying Documents now or hereafter constituted relating to or affecting the use or occupancy Project, and, upon request from Landlord, Tenant shall promptly recognize such Underlying Documents by executing a commercially reasonable form of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or actsrecognition.

Prohibited Uses. The Tenant shall not commit or allow any waste and shall carry on the Permitted Use in strict accordance with all Applicable Laws and the Landlord’s reasonable rules and regulations governing the same. Objectionable odors (a) Tenant will not use, occupy or permit the use or occupancy of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any including those inherent to cannabis manufacturing and/or its usage and/or storage (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoningas caused by terpenes), environmental and utility conservation matters which the Tenant acknowledges are “objectionable”) from the Premises shall, at the Tenant’s sole expense, be exhausted, filtered or otherwise managed, in such a manner as to: prevent their affecting the air quality at any adjacent or neighboring properties in a material way (hereinafter including parts of the Greater Lands that do not form part of the Premises (the “Legal RequirementsExcluded Greater Lands”), (ii) covenants, conditions), or restrictions applicable short circuiting into any fresh air vents, all in a manner which is compliant with Applicable Laws. If the Landlord reasonably determines that objectionable odors are adversely affecting the air on any adjacent or neighboring properties contrary to Applicable Law (including the Excluded Greater Lands), or short circuiting into any fresh air vents, or forming a legal nuisance to neighboring properties (or a material interference with the Excluded Greater Lands), and the Tenant, upon request by the Landlord, fails to forthwith take whatever steps are necessary to rectify such issue within a reasonable period of time, or if the situation cannot be resolved in compliance with Applicable Laws and to the satisfaction of the Landlord, in its reasonable discretion, the Landlord shall have, the right, but not the obligation, to enter the Premises and appearing rectify the situation and the Tenant shall pay to the Landlord, promptly upon demand, any and all reasonable costs which may be incurred by the Landlord in completing such rectifying work, together with an administration fee of record in the office fifteen percent (15%) of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) costs. The Tenant shall not keep use the Premises in a manner which does or permit to be kept any substance incould result in excessive demands being placed on the Building Systems; it being acknowledged and agreed, or conduct or permit to be conducted any operation fromhowever, any that the Tenant and Landlord have consulted on the Tenant’s use of the Premises which is not reasonably consistent with for the Permitted Use for and such Premises use does not in itself and which might emit offensive odors or conditionsshall not be deemed in itself to violate this paragraph. Notwithstanding the foregoing, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste indemnify and hold harmless the Landlord (including in respect of all legal fees on a solicitor and his own client basis) related to any claim of the Premisesnuisance. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.

Prohibited Uses. (a) Tenant will not use, occupy or permit the use or occupancy of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant Tenant's agents shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit suffer to be committed any action waste upon the Premises. Tenant and Tenant's agents shall not do or circumstance permit anything to be done in or about the Premises or Common Area which will in any way obstruct or interfere with the rights of other tenants of the Building, other authorized users of the Common Area, or occupants of neighboring property, or injure or annoy them. Tenant and Tenant's agents shall not use or allow the Premises to be used for any unlawful, immoral or hazardous purpose or any purpose not permitted by this Lease nor shall Tenant or Tenant's agents cause, maintain, or permit any nuisance in, on or about the Premises, . Tenant and Tenant's agents shall not do or permit anything to be done in or about the Premises nor bring or keep anything therein whichin or about the Premises which will in any way increase the existing rate or affect any insurance upon the Premises, directly Common Area, Land or indirectlyBuilding or any part thereof or any of its contents, would or might cause a cancellation of any insurance policy covering such the Premises, Building, Land or Common Area or any part thereof or any of its con- tents, nor shall Tenant or Tenant's agents keep, use or sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with insurance. In the requirements event the rate of any board insurance upon the Premises, Building, Land or Common Area or any part thereof or any of fire underwriters its contents is increased because of the acts or omissions of Tenant or Tenant's agents, Tenant shall pay, as Additional Rent, the full cost of such increase; provided, however, this provision shall in no event be deemed to constitute a waiver of Landlord's right to declare a default hereunder by reason of such increase or of any other similar body now rights or hereafter constituted relating to remedies of Landlord in connection with such increase. Tenant and Tenant's agents shall not place any loads upon the floor, walls or affecting ceiling of the use Premises which would endanger the Building or occupancy of all the structural elements thereof or of the Premises, excluding such structural changes as do not relate nor place any harmful liquids in the drainage system of the Building or Common Area. No waste materials or refuse shall be dumped upon or permitted to or affect the use or occupancy remain upon any part of the Premises, Land, Common Area or as are not related Building except in enclosed trash containers designed for that purpose by Landlord. No materials, supplies, equipment, finished products (or semi-finished products), raw materials, or other articles of any nature shall be stored upon, or be permitted to remain on, any portion of the Land, Common Area or afforded by Tenant’s improvements or actsBuilding outside the Premises.

Prohibited Uses. (a) Tenant will Sublessee shall not use, occupy or suffer or permit the use of, or occupancy of suffer or permit anything to be done in the Sublease Premises or the Building (i) which would violate any of the Premises covenants, agreements, terms, provisions and conditions of this Sublease, (ii) for any purpose unlawful purposes or in any manner which is unlawful manner, or may be, directly or indirectly(iii) which, in violation the reasonable judgment of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates Sublessor or ordinances of any governmental authority Landlord shall in any way applicable material respect (a) impair or tend to Tenant impair the appearance or reputation of the Building in such a manner so as to detract from the quality of conditions at the Building as compared with other comparable buildings in the Boston University Medical Campus, (b) impair or interfere with any of the Building services or the proper and economic heating, cleaning, air conditioning or other servicing of the Building, or (c) occasion discomfort, inconvenience or annoyance to any of the other tenants or occupants of the Building, whether through the transmission of noise or noxious or offensive odors or otherwise. Without limiting the generality of the foregoing, no food (except in connection with customary office vending machines, coffee service facilities and lunch room facilities set forth on the Complete Plans or other plans approved by Sublessor, provided such machines and facilities are used for and by occupants of the Sublease Premises only and their guests and further provided Sublessee pays any resulting increased costs pursuant to Section 13.8 and the other applicable provisions of this Sublease) shall be prepared or served for public or commercial consumption on or about the Sublease Premises; no intoxicating liquors or alcoholic beverages shall be sold or otherwise served to the general public on or about the Sublease Premises; no lottery tickets (even where the sale of such tickets is not illegal) shall be sold and no gambling, betting or wagering shall otherwise be permitted on or about the Sublease Premises; no loitering shall be permitted on or about the Sublease Premises; and no loading or unloading of supplies or other material to or from the Sublease Premises shall be permitted on the Lot except during such hours as the Building is customarily open for business. The Sublease Premises shall be maintained by Sublessee in a sanitary condition, kept free from noxious or offensive odors (including but not limited to zoningrodent or other laboratory animal odors) and kept free from vermin and, environmental and utility conservation matters except as provided herein below, rodents. Notwithstanding anything contained herein to the contrary, Sublessee may maintain not more than a maximum number of five thousand (hereinafter “Legal Requirements”), (ii5,000) covenants, conditions, or restrictions applicable to such Premises and appearing of record rodents in the office Sublease Premises at any one time during the Term provided (i) Sublessee delivers to Sublessor within thirty (30) days after the Term Commencement Date a complete report of the county recorder number of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.rodents

Prohibited Uses. Tenant shall not use the Premises: (ai) Tenant will not use, occupy or permit the use or occupancy of any In violation of the Premises restrictive covenants described in Section 9.10 of that certain Declaration of Protective Covenants and Owners Association for any purpose Cool Springs East Side dated October 4, 1994, of record in Book 1235, page 725, Register's Office for Williamson County, Tennessee (the "Protective Covenants"), a copy of which has been provided by Landlord to Tenant, or in any manner which is or may be, directly or indirectly, in violation of the rules and regulations described in Section 12b hereof; (ii) In any (i) judicial decisionsmanner that constitutes a nuisance or trespass, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority will in any way applicable to Tenant violate any law, statute, ordinance or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, governmental rule or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements regulation now in force or which may hereafter be in force and enacted or promulgated, (iii) In any manner that will adversely affect or interfere with any services required to be furnished by Landlord to Tenant, or to any other tenants or occupants of the Building or with the requirements proper and economical rendition of any board such service. (iv) In any manner that will in any way obstruct or interfere with the rights of fire underwriters other tenants of the Building or injure them, or use or allow the Premises to be used for any unlawful purpose, or commit or suffer to be committed any waste in, on or about the Premises; (v) In any manner which increases any insurance premiums, or makes such insurance unavailable to Landlord on the Building; provided that, in the event of an increase in Landlord's insurance premiums which results from Tenant's use of the Premises, Landlord may elect to permit the use and charge Tenant for the increase in premiums, and Tenant's failure to pay Landlord, on demand, the amount of such increase shall be an event of default (in any action or proceeding wherein Landlord and Tenant are parties, a schedule or "make up" of rates applicable to the Building issued by the Tennessee Insurance Bureau, or other similar body now fixing such fire insurance rates, shall be conclusive evidence of the facts therein stated and the several items and charges in the fire insurance rates therein); (vi) In any manner that creates unusual demands for electricity, heating or hereafter constituted relating air conditioning (except as permitted by Section 4(c) below); or (vii) For any purpose except the Permitted Use, unless consented to by Landlord in writing. (viii) That shall cause or affecting permit the use, generation, storage or disposal in or about the Premises or the Building of any substances, materials or wastes subject to regulation under Federal, State or local laws from time to time in effect concerning hazardous, toxic or radioactive materials (excluding the storage and use or occupancy of normal cleaning supplies and office supplies customarily used for the Permitted Use, all of the Premiseswhich shall be permitted without Landlord's consent so long as such items are stored and used in compliance with applicable environmental laws), excluding such structural changes as do not relate to unless Tenant shall have received Landlord's prior written consent, which Landlord may withhold or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or actsat any time revoke in its sole discretion.

Prohibited Uses. (a) Tenant will not use, occupy or permit the use or occupancy of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant Tenant's agents shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit --------------- suffer to be committed any action waste upon the Premises. Tenant and Tenant's agents shall not do or circumstance permit anything to be done in or about the Premises or Common Area which will in any way obstruct or interfere with the rights of any other tenants of the Building, other authorized users of the Common Area, or occupants of neighboring property, or injure or annoy them. Tenant and Tenant's agents shall not use or allow the Premises to be used for any unlawful, immoral or hazardous purpose or any purpose not permitted by this Lease, nor shall Tenant or Tenant's agents cause, maintain, or permit any nuisance in, on or about the Premises, . Tenant and Tenant's agents shall not do or permit anything to be done in or about the Premises nor bring or keep anything therein whichin the Premises which will in any way increase the rate of any insurance upon any portion of the Project or any of its contents, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premisesany portion of the Project or any of its contents, nor shall Tenant or Tenant's agents keep, use or sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with insurance. In the requirements event the rate of any board insurance upon any portion of fire underwriters the Project or any of its contents is increased because of Tenant's particular use of the Premises or that of Tenant's agents, Tenant shall pay, as Additional Rent, the full cost of such increase; provided, however this provision shall in no event be deemed to constitute a waiver of Landlord's right to declare a default hereunder by reason of the act or conduct of Tenant causing such increase or of any other similar body now rights or hereafter constituted relating to remedies of Landlord in connection therewith. Tenant and Tenant's agents shall not place any loads upon the floor, walls or affecting ceiling of the use Premises which would endanger the Building or occupancy of all the structural elements thereof or of the Premises, excluding such structural changes as do not relate to or affect nor place any harmful liquids in the use or occupancy drainage system of the PremisesBuilding or Common Area. No waste materials or refuse shall be dumped upon or permitted to remain upon any part of the Project except in enclosed trash containers designated for that purpose by Landlord. No materials, supplies, equipment, finished products (or semifinished products), raw materials, or as are not related other articles of any nature shall be stored upon, or be permitted to or afforded by Tenant’s improvements or actsremain on, any portion of the Project outside the Premises.

Prohibited Uses. Tenant further covenants and agrees that Tenant shall not use, or suffer or permit any person or persons to use, the Premises or any part thereof for any use or purpose in violation of Applicable Laws. Landlord shall have the right to impose Rules and Regulations regarding the use of the Project, as reasonably deemed necessary by Landlord with respect to the orderly operation of the Project, and Tenant shall comply with such Rules and Regulations. Nothing contained in this Lease shall be construed to impose upon Landlord any duty or obligation to enforce the rules and regulations or the terms, covenants or conditions in any other lease as against any other tenant and Landlord shall not be liable to Tenant for violation of the same by any other tenant, its servants, employees, agents, contractors, visitors, invitees or licensees. Tenant shall not do or permit anything to be done in or about the Premises which will in any way (a) Tenant will not usedamage the reputation of the Project (provided, occupy or permit however, the use of the Premises for the Permitted Use (including vivarium use) shall not be deemed in and of itself to damage the reputation of the Project), (b) impair, interfere with or occupancy otherwise diminish the quality of any of the Building services or the proper and economic heating, cleaning, ventilating, air conditioning or other servicing of the Building or Premises, or the use of any of the Common Areas, (c) obstruct or interfere with the rights of other tenants or occupants of the Building, or injure them, (d) use or allow the Premises to be used for any purpose improper, unlawful or objectionable purpose, (e) cause laboratory odors or noises (that are not typical of First Class Life Sciences Projects in which vivariums are operated) or harmful air emissions to emanate from the Premises; (f) increase such insurance rates on the Building or on property located therein over that applicable when Tenant first took occupancy of the Premises hereunder, or (g) cause, maintain or permit any manner which is legal nuisance in, on or may beabout the Premises. Furthermore, directly or indirectly, in violation of any Tenant shall not (i) judicial decisionsplace or maintain any garbage, ordertrash, injunctionsrubbish or other refuse (collectively, writs“Trash”), statutes, rulings, rules, regulations, promulgations, directives, permits, certificates signage (except as may be permitted by Section 23 below) or ordinances of any governmental authority other articles in any way applicable to Tenant vestibule or entry of the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, on the footwalks or restrictions applicable to such Premises and appearing of record in corridors adjacent thereto or elsewhere on the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any exterior of the Premises, nor bring obstruct any driveway, corridor, footwalk, parking area, mall or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.Common

Prohibited Uses. (a) Tenant will not use, occupy or permit the use or occupancy of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant Tenant's agents shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit suffer to be committed any action waste upon the Premises. Tenant and Tenant's agents shall not do or circumstance permit anything to be done in or about the Premises or Common Area which will in any way obstruct or interfere with the rights of any authorized users of the Common Area, or injure or annoy them. Tenant shall not conduct or permit any auction or sale open to the public to be held or conducted on or about the Premises or Common Area. Tenant and Tenant's agents shall not use or allow the Premises to be used for any unlawful, immoral or hazardous purpose or any purpose not permitted by this Lease, nor shall Tenant or Tenant's agents cause, maintain, or permit any nuisance in, on or about the Premises, . Tenant and Tenant's agents shall not do or permit anything to be done in or about the Premises or Common Area nor bring or keep anything therein whichin the Premises or Common Area which will in any way increase the rate of any insurance upon the Premises or Common Area or any part thereof or any of its contents, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premisesthe Premises or Common Area or any part thereof or any of its contents, nor shall Tenant or Tenant's agents keep, use or sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance unless upon the Premises or Common Area or any part thereof or any of its contents is increased because of the acts or omissions of Tenant provides additional insurance coverage extending protection or Tenant's agents, Tenant shall pay, as Additional Rent, the full cost of such increase to cover all risks associated the extent attributable solely to Tenant's or its agents' acts or omissions; provided however this provision shall in no event be deemed to constitute a waiver of Landlord's rights or remedies of Landlord in connection with those articles. such increase. Tenant and Tenant's agents shall not place any loads upon the floor, walls or ceiling of the Premises which would endanger the Premises or the structural elements thereof, nor place any harmful liquids in the drainage system of the Premises. No waste materials or refuse shall be dumped upon or permitted to remain upon any part of the Premises or Common Area except in enclosed trash containers. No materials, supplies, equipment, finished products (f) or semi-finished products), raw materials, or other articles of any nature shall be stored upon, or be permitted to remain on, any portion of the Common Area. Tenant shallshall not allow any activity which in the reasonable opinion of Landlord is detrimental to the operation of the Common Area or to tenants of Landlord in other buildings located on the Common Area or upon real property owned by Landlord adjacent to the Common Area, including but not limited to any picketing, work stoppage, or other concerted activity. Landlord shall have the right to require Tenant, at Tenant’s sole cost 's own expense and expensewithin a reasonable period of time, promptly comply with all Legal Requirements now in force to use Tenant's commercially reasonably efforts to terminate or which may hereafter be in force and control any such picketing, work stoppage or other concerted activity to the extent necessary to eliminate any interference with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all operation of the Premises, excluding Common Area or such structural changes as tenants. Failure by Tenant to use its commercially reasonable efforts to do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded so shall be a Default by Tenant’s improvements . Nothing contained in this paragraph shall be construed as placing Landlord in an employer-employee relationship with any of Tenant's employees or actswith any other employees who may be involved in such activity.

Prohibited Uses. Tenant shall not use, permit the use of, permit anything to be done in or on or anything to be brought into or onto or kept in or on the Premises, the Building, the Property or any part of thereof (i) which would violate any covenant, agreement, term, provision or condition of this Lease, (ii) for any unlawful purpose or in any unlawful manner, or (iii) which, in the reasonable judgment of Landlord shall in any way (a) impair or tend to impair the appearance or reputation of the Building or the Property, (b) impair or interfere with or tend to impair or interfere with any of the Building or Property services or the proper and economic heating, cleaning, air conditioning or other servicing of the Building or the Property or any portion thereof or with the use of the Building or the Property or any portion thereof, or (c) occasion discomfort, inconvenience or annoyance to any other tenant, licensee or other occupant of the Building or the Property or any neighboring property, whether through the transmission of noise or odors or vibrations or otherwise. Without limiting the generality of the foregoing, Tenant will shall not use, permit any vending machines in the Premises or use or occupy or permit the use or occupancy of any occupation of the Premises or any part of the Premises as or for any purpose a restaurant business or in any manner which is for the sale or may befurnishing free of charge of food, directly liquors, frozen deserts, ice cream, beverages, or indirectlyother edible products, in violation for public stenography, or for the conducting of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates aspect of banking business; no food shall be prepared or ordinances of any governmental authority served for consumption on or about the Premises; no intoxicating liquors or alcoholic beverages shall be sold or otherwise permitted in any way applicable to Tenant or about the Premises, including but the Building or elsewhere on the Property; no lottery tickets (even where the sale of such tickets is not limited illegal) shall be sold and no gambling, betting or wagering shall otherwise be permitted in or about the Premises, the Building or elsewhere on the Property; no loitering shall be permitted in or about the Premises, the Building or elsewhere on the Property; and no loading or unloading of supplies or other material to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such from the Premises and appearing of record shall be permitted in the office of Building or elsewhere on the county recorder of the county Property except at times and in which such Premises are located on or before the date on which such Premises became subject locations to this Lease, or (iii) insurance requirements. (b) be designated by Landlord. Tenant shall not keep bring or permit to be kept brought into or keep in or on the Premises, the Building or elsewhere on the Property any oil or any toxic, hazardous, inflammable, combustible or explosive fluids, materials, chemicals or substances, (including without limitation any hazardous substances within the meaning of Chapter 21E of the Massachusetts General Laws and any medical waste or any fluid, material, chemical or substance in, or conduct or permit considered to be conducted any operation from, any of biologically hazardous) (except in the Premises which is not reasonably consistent with the Permitted Use for where such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit are related to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any Tenant's use of the Premises, nor bring provided that the same are stored and handled in a proper fashion consistent with applicable legal standards), or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit any odors to emanate from or permeate the Premises. The Premises shall be keptmaintained in a sanitary condition, used or sold and kept free of rodents and vermin. Tenant shall suitably store all trash and rubbish in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate the Building or elsewhere on the Property in locations designated by Landlord from time to time. The language of this Section prohibiting the preparation or affect serving of food for consumption on or about the use or occupancy Premises notwithstanding, but subject to the other terms and conditions of the PremisesLease and subject to the other terms and conditions of this Section entitled “Prohibited Uses.”, or as are Tenant may, with Landlord's prior written consent, install at Tenant's sole expense, one bottled water dispenser (utilizing water bottles with a capacity of not related to or afforded more than five gallons each and dispensing not more than one bottle at a time without manually removing and replacing the one bottle from which water is dispensed), coffee maker, microwave and refrigerator for use by Tenant’s improvements or acts.

Prohibited Uses. Tenant further covenants and agrees that Tenant shall not use, or suffer or permit any person or persons to use, the Premises or any part thereof for any use or purpose contrary to the provisions of the Rules and Regulations set forth in Exhibit D, attached hereto (provided that Tenant shall only be required to abide by and observe any changes to the Rules and Regulations made after the date of this Lease to the extent such changes (a) are applied in a non-discriminatory manner; (ii) do not create an unreasonable interference with or unreasonably prevent Tenant will from using the Premises for the Permitted Use, and (b) do not usematerially diminish the rights or materially increase the obligations of Tenant under this Lease), occupy or in violation of the laws of the United States of America, the State of California, or the ordinances, regulations or requirements of the local municipal or county governing body or other lawful authorities having jurisdiction over the Project, including, without limitation, any such laws, ordinances, regulations or requirements relating to hazardous materials or substances, as those terms are defined by Applicable Laws now or hereafter in effect. Tenant shall not do or permit anything to be done in or about the Premises which will in any way materially obstruct or interfere with the rights of other tenants or occupants of the Building, or injure or unreasonably annoy them or use or occupancy of allow the Premises to be used for any unlawful purpose, nor shall Tenant cause, maintain or permit any nuisance in, on or about the Premises. Tenant shall comply with, and Tenant’s rights and obligations under the Lease and Tenant’s use of the Premises for any purpose or in any manner which is or may beshall be subject and subordinate to, directly or indirectlyall easements, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or and restrictions applicable to such Premises and appearing of record in affecting the office of the county recorder of the county in Project which such Premises are located on or before first recorded after the date on which such Premises became subject to of this Lease; provided, or (iii) insurance requirements. (b) Tenant however, any such instrument shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is (and could not reasonably consistent with the Permitted Use for such Premises by its terms) materially and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, increase any obligations or as are not related to decrease any rights of Tenant hereunder, nor shall any such instrument increase the rights or afforded by Tenant’s improvements or acts.decrease the obligations of Landlord

Prohibited Uses. The uses prohibited under this Lease shall include, without limitation, use of the Premises or a portion thereof for (i) offices of any agency or bureau of the United States or any state or political subdivision thereof; (ii) offices or agencies of any foreign governmental or political subdivision thereof; (iii) offices of any health care professionals or service organization open to the general public; (iv) schools or other training facilities which are not ancillary to corporate, executive or professional office use; (v) retail or restaurant uses (other than the Cafeteria (defined below)); or (vi) communications firms such as radio and/or television stations. Tenant further covenants and agrees that it shall not use, or suffer or permit Tenant Party to use, the Premises or any part thereof for any use or purpose contrary to the rules and regulations reasonably promulgated by Landlord from time to time ("Rules and Regulations"), the current set of which (as of the date of this Lease) is attached to this Lease as Exhibit D; or in violation of the laws of the United States of America, the State of California, or the ordinances, regulations or requirements of the local municipal or county governing body or other lawful authorities having jurisdiction over the Project, including, without limitation, any such laws, ordinances, regulations or requirements relating to Hazardous Materials now or hereafter in effect; provided, however, (a) Landlord shall not enforce, change or modify the Rules and Regulations in a discriminatory manner, (b) any modifications to the Rules and Regulations shall be subject to Landlord's Obligations to Minimize Tenant Interference, (c) any modifications to the Rules and Regulations shall not becoming binding on Tenant until the tenth (10th) business day after Tenant receives a written copy thereof, and (d) no modifications to the Rules and Regulations will apply retroactively. Landlord agrees that the Rules and Regulations shall not use, occupy be unreasonably modified or enforced in a manner which will unreasonably interfere with the normal and customary conduct of Tenant's business. Tenant shall not do or permit the use anything to be done in or occupancy of any of about the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority will in any way applicable to Tenant damage the reputation of the Project or obstruct or interfere with the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditionsrights of other tenants or occupants of the Building, or restrictions applicable to such injure or unreasonably annoy them or use or allow the Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept used for any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premisesunlawful purpose, nor shall Tenant sell cause, maintain or permit to be keptany nuisance in, used or sold in on or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.

Prohibited Uses. (a) Tenant will not use, occupy or permit the use or occupancy of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant Tenant's agents shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit suffer to be committed any action waste upon the Premises. Tenant and Tenant's agents shall not do or circumstance permit anything to be done in or about the Premises which will unreasonably obstruct or interfere with the rights of any occupants of neighboring property, or injure or annoy them. Tenant shall not conduct or permit any auction or sale open to the public to be held or conducted on or about the Premises. Tenant and Tenant's agents shall not use or allow the Premises to be used for any unlawful purpose or any purpose not permitted by this Lease, nor shall Tenant or Tenant's agents cause, maintain, or permit any nuisance in, on or about the Premises. Tenant and Tenant's agents shall not do or permit anything to be done in or about the Premises nor bring or keep anything therein which, directly or indirectly, would or might in the Premises which will cause a cancellation of any insurance policy covering such Premisesthe Premises or any part thereof or any of its contents, nor shall Tenant or Tenant's agents keep, use or sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance unless upon the Premises or any part thereof or any of its contents is increased because of the acts or omissions of Tenant provides additional insurance coverage extending protection or Tenant's agents, Tenant shall pay, as Additional Rent, the full cost of such increase; provided however this provision shall in no event be deemed to cover all risks associated constitute a waiver of Landlord's right to any other rights or remedies of Landlord in connection with those articles. such increase. Tenant and Tenant's agents shall not place any loads upon the floor, walls or ceiling of the Premises which would endanger the Premises or the structural elements thereof, nor place any harmful liquids in the drainage system of the Premises. No waste materials or refuse shall be dumped upon or permitted to remain upon any part of the Premises except in enclosed trash containers. No materials, supplies, equipment, finished products (f) or semi-finished products), raw materials, or other articles of any nature shall be stored upon, or be permitted to remain on, any portion of the Premises. Tenant shallshall not allow any activity which in the reasonable opinion of Landlord is detrimental to the operation of other buildings located upon real property owned by Landlord adjacent to the Premises, including but not limited to any picketing, work stoppage, or other concerted activity. Landlord shall have the right to require Tenant, at Tenant’s sole cost 's own expense and expensewithin a reasonable period of time, promptly comply with all Legal Requirements now in force to use Tenant's best efforts to terminate or which may hereafter be in force and control any such picketing, work stoppage or other concerted activity to the extent necessary to eliminate any interference with the requirements of any board of fire underwriters operation or other similar body now or hereafter constituted relating such tenants. Failure by Tenant to or affecting the use or occupancy of all of the Premises, excluding such structural changes as its best efforts to do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded so shall be a Default by Tenant’s improvements . Nothing contained in this paragraph shall be construed as placing Landlord in an employer-employee relationship with any of Tenant's employees or actswith any other employees who may be involved in such activity.

Prohibited Uses. (a) Tenant will It is agreed that the Premises shall not use, occupy or permit the use or occupancy of be used for any of the Premises following uses, and LESSOR'S consent to such uses will not be provided a bar, night club, lounge, dance hall, discotheque, teenager gathering place, massage parlor, adult book store, or similar business catering to pornographic interests, establishments engaged in the business of selling, distributing, displaying, or offering for sale, ▇▇▇▇▇ clips, water pipes, bongs, coke spoons, hypodermic syringes or other paraphernalia commonly used in the use of or ingestion of illicit drugs (including, without limitations, a so-called “head shop”), bowling alley, kiosk business, firearms shooting range, bingo hall, theatre, funeral parlor, flea market, amusement or video arcade, pool or billiard hall, pawn shop, gun shop, tattoo parlor, car wash, automobile repair shop, or any purpose or business servicing motor vehicles in any manner respect, including, without limitation, any quick lube oil change service, tire center or gasoline or service station or facility, any carnival, amusement park or circus, hotel/motel, area for commuter parking, any use which is involves the sale or may bedisplay of merchandise generally offensive to the public, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority use which will in any way applicable to Tenant increase the existing rate of or affect any fire or extended coverage insurance policy upon the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditionsbuilding of which the Premises are a part, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor the building of which the Premises are a part. The foregoing list shall Tenant sell not be interpreted as a limitation or permit restriction of LESSOR'S discretion in its decision on consent to be kept, used or sold in or about any uses of the Premises by LESSEE. Notwithstanding the foregoing or anything else to the contrary contained in this lease, LESSEE is prohibited from using the Premises or any articles which may portion thereof for the sale or distribution of alcoholic beverages without the prior written consent of LESSOR. Adequate liquor liability insurance with LESSOR as an additional insured shall be prohibited by a standard form policy of prerequisite, although not the only precondition, to LESSOR'S consent. LESSEE shall not conduct sidewalk sales, tent sales, auction sales, warehouse sales or fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, sales at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or actsin the Common Facilities.

Prohibited Uses. (a) Tenant will not use, occupy or permit the use or occupancy of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant Tenant’s agents shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit suffer to be committed any action waste upon the Premises. Tenant and Tenant’s agents shall not do or circumstance permit anything to be done in or about the Premises or Common Area which will in any way obstruct or interfere with the rights of any authorized users of the Common Area, or occupants of neighboring property, or injure or annoy them. Tenant and Tenant’s agents shall not use or allow the Premises to be used for any unlawful, immoral or hazardous purpose (except the foregoing shall not preclude Tenant from using Hazardous Materials in connection with Tenant’s business that are approved by Landlord pursuant to the terms of Paragraph 6.4 below) or any purpose not permitted by this Lease, nor shall Tenant or Tenant’s agents cause, maintain, or permit any nuisance in, on or about the Premises, . Tenant and Tenant’s agents shall not do or permit anything to be done in or about the Premises nor bring or keep anything therein whichin the Premises which will in any way increase the rate of any insurance upon any portion of the Project or any of its contents, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premisesany portion of the Project or any of its contents, nor shall Tenant or Tenant’s agents keep, use or sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance unless upon any portion of the Project or any of its contents is increased because of the acts or omissions of Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at or Tenant’s sole agents, Tenant shall pay, as Additional Rent, the full cost of such increase. Tenant and expenseTenant’s agents shall not place any loads upon the floor, promptly comply with all Legal Requirements now in force walls or ceiling of the Premises which may hereafter be in force and with would endanger the requirements of any board of fire underwriters Building or other similar body now the structural elements thereof or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect nor place any harmful liquids in the use or occupancy drainage system of the PremisesBuilding or Common Area. No waste materials or refuse shall be dumped upon or permitted to remain upon any part of the Project except in properly designed and constructed trash receptacles or discharge systems and in compliance with all applicable Laws pertaining to the disposal of such waste materials or refuse. No materials, supplies, equipment, finished products (or semifinished products), raw materials, or as are not related other articles of any nature shall be stored upon, or be permitted to or afforded by Tenant’s improvements or actsremain on, any portion of the Project outside the Premises.

Prohibited Uses. Tenant shall not use the Premises or allow the Premises to be used for any purpose that (a) Tenant will not useis illegal, occupy or permit the use or occupancy of any of the Premises for any purpose or (b) in any manner which causes, creates or results in a waste or a private or public nuisance, (c) is of a nature to involve substantial hazard, such as the manufacture or use of explosives, chemicals or products that may be, directly explode or indirectly, in violation that otherwise may harm the health or welfare of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant persons or the Premisesphysical environment (provided that the research, including but development and manufacture of pharmaceutical and biotechnology products shall not limited be deemed to zoningbe inherently hazardous and is specifically permitted hereunder, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Leasethe provisions of Article 12), or (iiid) insurance requirements. (b) involves the release of any Hazardous Materials, except for Hazardous Materials that Tenant has the right to use on the Premises pursuant to Section 12.3. Tenant shall not keep or permit to be kept place any substance inloads upon the floors, walls, or conduct or permit to be conducted any operation from, any of ceiling which endanger the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditionsstructure, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain place any waste to any of Hazardous Material in the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy drainage system of the Premises, or as are overload existing electrical or other mechanical systems. Tenant shall not related use any machinery or equipment which causes any substantial noise or vibration. No waste materials or refuse shall be dumped upon or permitted to remain upon any part of the Premises or afforded outside of the Premises except in trash containers placed inside exterior enclosures designated by Tenant’s improvements Landlord for that purpose or actsinside of the Premises where approved by Landlord. No materials, supplies, equipment, finished products or semi-finished products, raw materials or articles of any nature shall be stored outside or permitted to remain outside the Premises or on any portion of the Exterior Area unless otherwise approved by Landlord in its sole discretion. No loudspeaker or other device, system or apparatus that can be heard by the occupants of any neighboring property shall be used in or at the Premises without the prior written consent of Landlord, which consent shall not be unreasonably withheld. No explosives or firearms shall be brought into the Premises.

Prohibited Uses. (a) Tenant will shall not use, occupy use or permit the Premises to be used in any manner other than the Permitted Uses. Notwithstanding anything contained herein to the contrary, Tenant shall not use or occupancy of any of permit the Premises for any purpose or to be used in any manner which is or may be, directly or indirectly, in violation of any would (i) judicial decisionsbe contrary to any statute, rule, order, injunctionsordinance, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates requirement or ordinances of any governmental authority in any way regulation applicable to Tenant the Premises or the PremisesTenant's use thereof including, including but not in no way limited to zoning, environmental and utility conservation matters the Environmental Laws (hereinafter “Legal Requirements”as such term is hereafter defined), ; (ii) covenantsviolate any certificate of occupancy or building permit affecting the Premises or any part thereof; (iii) cause material injury to the Premises or any part thereof; (iv) constitute a public or private nuisance or waste; (v) render the insurance on the Premises void or the insurance risk more hazardous or create any defense to payment; (vi) cause or is likely to cause material damage to the Premises or any equipment or the systems in the Premises; or (vii) violate any covenant, conditions, condition or restrictions applicable to such Premises and appearing restriction of record in the office of the county recorder of the county in which any material respect (any such Premises are located on or before the date on which such Premises became subject use is herein referred to this Leaseas a "Prohibited Use"). Tenant agrees that it will promptly, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems upon discovery of any such buildingsProhibited Use, take all necessary steps to compel the discontinuance of such use. Landlord represents and warrants to Tenant that the Premises have not been used for any Prohibited Use prior to the Term hereof by Landlord or, to Landlord's knowledge, without inquiry, any other party. Landlord hereby indemnifies and holds harmless Tenant for any Prohibited Use that occurred on the Premises prior to, or affect that occurs thereon after, the structural integrity Term hereof. The foregoing indemnity shall survive the expiration or termination of any such buildings in any waythis Lease. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.

Prohibited Uses. (a) Tenant will shall not use, occupy do or permit the use or occupancy of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit anything to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance done in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might which will cause a cancellation of any insurance inatrarice policy covering such the Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those these articles. (fb) Tenant shall not use the Premises or permit anything to be done in or about the Premises which will in any way conflict with any law, statute, ordinance or governmental rule or regulation or requirement of duly constituted public authorities now in force or which may hereafter be enacted, promulgated or created. Tenant shall, at Tenant’s 's sole cost and expense, promptly comply with all Legal Requirements laws, statutes, ordinances and governmental rules, regulations or requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the die Premises, excluding such including structural changes as do not that relate to or affect the use use (c) Tenant shall comply with all requirements of any recorded restrictive covenants or occupancy bylaws of any association affecting the Premises. Tenant acknowledges receipt of a copy of the Declaration of Covenants, Conditions and Restrictions and a copy of the Bylaws of the Condominium Owners' Association affecting the Premises, or as are . (d) Tenant shall not related to or afforded by Tenant’s improvements or actspermit smoking on the Premises at any time.

Prohibited Uses. Notwithstanding any other provision of this Lease, Tenant shall not use, or suffer or permit the use or occupancy of, or suffer or permit anything to be done in or anything to be brought into or kept in or about the Premises or the Building or any part thereof (including, without limitation, any materials, appliances or equipment used in the construction or other preparation of the Premises and furniture and carpeting): (a) Tenant will not usewhich would violate any of the covenants, occupy agreements, terms, provisions and conditions of this Lease or permit the Rules and Regulations or that are otherwise applicable to or binding upon the Premises; (b) which, in the reasonable judgment of Landlord shall in any way (i) impair the appearance or reputation of the Building; or (ii) impair, interfere with or otherwise diminish the quality of any of the Building services or the proper and economic heating, cleaning, ventilating, air conditioning or other servicing of the Building or Premises, or with the use or occupancy of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation other areas of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditionsBuilding, or restrictions applicable occasion discomfort, inconvenience or annoyance, or injury or damage to such Premises and appearing of record in the office any occupants of the county recorder Premises or other tenants or occupants of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or Building; (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance inwhich is inconsistent with the maintenance of the Building as a comparable first-class life sciences building in Boston in the quality of its maintenance, use, or conduct occupancy; (iv) adversely affect the LEED relating to Building Design and Construction (as defined below) (or permit to be conducted any operation from, any similar) certifiability of the Premises Building or any improvements therein or any LEED relating to Building Design and Construction or similar certifications previously obtained with respect to the Building; or (v) which is not reasonably consistent with would violate any then current exclusive use or right granted by Landlord to any tenant or occupant of the Permitted Use for such Premises and which might emit offensive odors Building (Landlord agreeing to provide notice of same within ten (10) business days following Tenant’s written request therefor); or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain which would violate any waste to any of the Premises. (d) Excluded Use set forth on Exhibit 11 attached hereto. Tenant shall not install or permit to remain use any improvements to any of the Premises which exceed the structural loads of floors electrical or walls other equipment of any buildings located on such Premiseskind which, or adversely affect in the mechanicalreasonable judgment of Landlord, plumbing or electrical systems of might cause any such buildingsimpairment, interference, discomfort, inconvenience, annoyance or affect the structural integrity of any such buildings in any wayinjury. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.

Prohibited Uses. (a) Tenant will not use, occupy or permit the use or occupancy of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant Tenant's agents shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit suffer to be committed any action waste upon the Premises. Tenant and Tenant's agents shall not do or circumstance permit anything to be done in or about the Premises which will unreasonably obstruct or interfere with the rights of any occupants of neighboring property, or injure or annoy them. Tenant shall not conduct or permit any auction or sale open to the public to be held or conducted on or about the Premises. Tenant and Tenant's agents shall not use or allow the Premises to be used for any unlawful purpose or any purpose not permitted by this Lease, nor shall Tenant or Tenant's agents cause, maintain, or permit any nuisance in, on or about the Premises. Tenant and Tenant's agents shall not do or permit anything to be done in or about the Premises nor bring or keep anything therein which, directly or indirectly, would or might in the Premises which will cause a cancellation of any insurance policy covering such Premisesthe Premises or any part thereof or any of its contents, nor shall Tenant or Tenant's agents keep, use or sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance unless upon the Premises or any part thereof or any of its contents is increased because of the acts or omissions, direct or indirect, of Tenant provides additional insurance coverage extending protection or Tenant's agents, Tenant shall pay, as Additional Rent, the full cost of such increase; provided however this provision shall in no event be deemed to cover all risks associated constitute a waiver of Landlord's right to any other rights or remedies of Landlord in connection with those articles. (f) such increase. Tenant shalland Tenant's agents shall not place any loads upon the floor, walls or ceiling of the Premises which would endanger the Premises or the structural elements thereof, nor place any harmful liquids in the drainage system of the Premises. No waste materials or refuse shall be dumped upon or permitted to remain upon any part of the Premises except in enclosed trash containers. Tenant shall not allow any activity which in the reasonable opinion of Landlord is detrimental to the operation of other buildings located upon real property owned by Landlord adjacent to the Premises, including but not limited to any picketing, work stoppage, or other concerted activity. Landlord shall have the right to require Tenant, at Tenant’s sole cost 's own expense and expensewithin a reasonable period of time, promptly comply with all Legal Requirements now in force to use Tenant's best efforts to terminate or which may hereafter be in force and control any such picketing, work stoppage or other concerted activity to the extent necessary to eliminate any interference with the requirements of any board of fire underwriters operation or other similar body now or hereafter constituted relating such tenants. Failure by Tenant to or affecting the use or occupancy of all of the Premises, excluding such structural changes as its best efforts to do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded so shall be a Default by Tenant’s improvements . Nothing contained in this paragraph shall be construed as placing Landlord in an employer-employee relationship with any of Tenant's employees or actswith any other employees who may be involved in such activity.

Prohibited Uses. (a) Tenant will shall not use, occupy or suffer or permit the use --------------- of, or occupancy of suffer or permit anything to be done in or anything to be brought into or kept in, the Demised Premises or any part thereof (i) which would violate any of the Premises for any purpose or in any manner which is or may becovenants, directly or indirectlyagreements, in violation terms, provisions and conditions of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”)this Lease, (ii) covenants, conditions, for any unlawful purposes or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Leaseany unlawful manner, or (iii) insurance requirements. which, in the reasonable judgment of Landlord shall in any way (a) impair or tend to impair the appearance or reputation of the Building, (b) Tenant shall not keep impair or permit interfere with or tend to be kept any substance in, impair or conduct or permit to be conducted any operation from, interfere with any of the Premises which is not reasonably consistent Building services or the proper and economic heating, cleaning, air conditioning or other servicing of the Building or Demised Premises, or with the Permitted Use for such Premises and which might emit offensive odors or conditionsuse of any of the other areas of the Building, or make undue noise or create undue vibrations. (c) Tenant shall not commit occasion discomfort, inconvenience or permit to remain any waste annoyance to any of the Premises. (d) Tenant shall not install other tenants or permit to remain any improvements to any occupants of the Premises which exceed Building, whether through the structural loads transmission of floors noise or walls odors or otherwise. Without limiting the generality of any buildings located the foregoing, no food shall be prepared or served for consumption on or about the Demised Premises; no intoxicating liquors or alcoholic beverages shall be sold on or about the Demised Premises; no lottery tickets (even where the sale of such tickets is not illegal) shall be sold and no gambling, betting or wagering shall otherwise be permitted on or about the Demised Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant ; no loitering shall not commit or permit to be committed any action or circumstance permitted in or about any the Demised Premises; and no loading or unloading of supplies or other material to or from the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor Demised Premises shall Tenant sell or permit be permitted on the Land except at times and in locations to be keptdesignated by Landlord. The Demised Premises shall be maintained in a sanitary condition, used or sold and all kept free of rodents and vermin. All trash and rubbish shall be suitably stored in or about any of the Demised Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating locations designated by Landlord from time to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or actstime.

Prohibited Uses. (a) Notwithstanding any other provision of this Lease, Tenant will shall not useuse the Premises or the Building, occupy or any part thereof, or suffer or permit the use and/or occupancy of the Premises or occupancy the Building or any part thereof by Tenant and/or Tenant’s agents, servants, employees, consultants, contractors, subcontractors, licensees and/or subtenants (collectively with Tenant, the “Tenant Parties”) (i) in a manner which would violate any of the covenants, agreements, terms, provisions and conditions of this Lease or otherwise applicable to or binding upon the Premises; (ii) for any unlawful purposes or in any unlawful manner; (iii) in a manner which, in the reasonable judgment of Landlord (taking into account the use of the Building as a combination institutional, office and retail building and the Permitted Uses) shall (a) impair the appearance or reputation of the Building; (b) impair, interfere with or otherwise diminish the quality of any of the Premises for Building services or the proper and economic heating, cleaning, ventilating, air conditioning or other servicing of the Building or Premises, or the use of any purpose of the Common Areas; (c) occasion discomfort, inconvenience or annoyance in any material respect (and Tenant shall not install or use any electrical or other equipment of any kind which, in the reasonable judgment of Landlord, will cause any such material impairment, interference, discomfort, inconvenience, annoyance or injury), or cause any injury or damage to any occupants of the Premises or other tenants or occupants of the Building or their property; or (d) cause harmful air emissions or any unusual or other objectionable odors, noises or emissions to emanate from the Premises; (iv) in a manner which is inconsistent with the operation and/or maintenance of the Building as a first-class combination institutional, office and retail facility; (v) for any fermentation processes whatsoever; (vi) in a manner which shall increase such insurance rates on the Building or may be, directly or indirectly, in violation on property located therein over that applicable when ▇▇▇▇▇▇ first took occupancy of any the Premises hereunder (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances provided that use of any governmental authority the Premises for the Permitted Uses generally shall not be deemed to result in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”such increase), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, ; or (iiivii) insurance requirementsfor any use listed in Exhibit 6 attached hereto and made a part hereof. (b) With respect to the use and occupancy of the Premises and the Common Areas, Tenant shall not keep will not: (i) place or maintain any garbage, trash, rubbish or other refuse (collectively, “Trash”), signage (except as may be permitted by Article 12 below) or other articles in any vestibule or entry of the Premises, on the footwalks or corridors adjacent thereto or elsewhere on the exterior of the Premises, nor obstruct any driveway, corridor, footwalk, parking area, mall or any other Common Areas; (ii) permit undue accumulations of or burn Trash within or without the Premises; (iii) permit the parking of vehicles so as to be kept interfere with the use of any substance indriveway, corridor, footwalk, parking area, or other Common Areas; (iv) receive or ship articles of any kind outside of those areas reasonably designated by Landlord; (v) conduct or permit to be conducted any operation fromauction, going out of business sale, bankruptcy sale (unless directed by court order), or other similar type sale in or connected with the Premises; (vi) use the name of Landlord, Fee Owner, or any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors Landlord’s affiliates or conditionssubsidiaries in any publicity, promotion, trailer, press release, advertising, printed, or make undue noise or create undue vibrations. display materials without Landlord’s prior written consent (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated withheld in Landlord’s sole discretion); (vii) permit or keep any animals other than trained certified service animals in the Building; or (viii) except in connection with those articles. (f) Tenant shall, at Tenant’s sole cost and expenseFitout and/or Alterations (hereinafter defined) approved by Landlord, promptly comply with all Legal Requirements now cause or permit any hole to be drilled or made in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all part of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or actsBuilding.

Prohibited Uses. (a) Tenant will shall not use, occupy or permit the use of, permit anything to be done in or occupancy on or anything to be brought into or onto or kept in or on the Premises, the Building, the Property or any part of thereof (i) which would violate any covenant, agreement, term, provision or condition of the Premises this Lease, (ii) for any unlawful purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Leaseunlawful manner, or (iii) insurance requirements. which, in the reasonable judgment of Landlord shall in any way (a) impair or tend to impair the appearance or reputation of the Building or the Property, (b) impair or interfere with or tend to impair or interfere with any of the Building or Property services or the proper and economic heating, cleaning, air conditioning or other servicing of the Building or the Property or any portion thereof or with the use of the Building or the Property or any portion thereof, or (c) occasion unreasonable discomfort, inconvenience or annoyance to any tenant, licensee or other occupant of any neighboring property, whether through the transmission of noise or odors or vibrations or otherwise. Notwithstanding anything above in this paragraph to the contrary, if and to the extent this paragraph provides for Landlord to exercise “reasonable judgment”, provided and to the extent Tenant’s use of the Premises is for the Permitted Use of the Premises only and otherwise in all respects in compliance with all applicable terms and conditions of this Lease, (A) Landlord agrees not to find that the permitted Use of the Premises in and of itself (x) impairs or tends to impair the appearance or reputation of the Building or the Property, (y) impairs or interferes with or tends to impair or interfere with any of the Building or Property services or the proper and economic heating, cleaning, air conditioning or other servicing of the Building or the Property or any portion thereof or with the use of the Building or the Property or any portion thereof; provided however that such limitation on Landlord’s “reasonable judgment” shall not apply with respect to Tenant’s acts or omissions outside the Premises, including, without limitation, Tenant’s acts or omissions in the Parking Areas, on the roof of the Building or elsewhere on the Property other than inside the Building and not visible from outside the Building; and (B), with respect to (c) above in this grammatical paragraph, in the event of a bona fide complaint from any tenant, licensee or other occupant of any neighboring property (a “Complaining Neighbor”), without diminishing Landlord’s ability to otherwise exercise “reasonable judgement” in requiring Tenant not to “occasion unreasonable discomfort, inconvenience or annoyance to any tenant, licensee or other occupant of any neighboring property, whether through the transmission of noise or odors or vibrations or otherwise”, Landlord agrees that Landlord shall not seize upon a de minimis and or unreasonable complaint of a Complaining Neighbor to disproportionately further a Landlord agenda to seek termination of the Term sooner than the Term Expiration Date. No outside storage of any sort shall be permitted at any time without the consent of Landlord obtained in advance in each instance. In the event Landlord grants Landlord’s consent with respect to outside storage (which Landlord, in Landlord’s discretion, may or may not grant or may condition), among other conditions, Landlord may condition Landlord’s consent upon Tenant, at Tenant’s expense, providing reasonable screening acceptable to Landlord. Tenant shall not keep bring or permit to be kept brought into or keep in or on the Premises, the Building or elsewhere on the Property any “Hazardous Materials”, which shall be defined as oil or any toxic, hazardous, inflammable, combustible or explosive fluids, materials, chemicals or substances, (including without limitation any hazardous substances within the meaning of Chapter 21E of the Massachusetts General Laws and any medical waste or any fluid, material, chemical or substance in, or conduct or permit considered to be conducted any operation from, any biologically hazardous) (except in the Premises where such are related to Tenant’s use of the Premises which is not reasonably consistent with for the Permitted permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed and then only provided the structural loads of floors or walls of any buildings located on such Premisessame are stored and handled in a proper fashion consistent with applicable legal standards and industry best practices), or adversely affect cause or permit any odors to emanate from the mechanicalPremises or any other portion of the Property. The Property shall be maintained in a sanitary condition, plumbing or electrical systems and kept free of any such buildings, or affect the structural integrity of any such buildings in any way. (e) rodents and vermin. Tenant shall not commit suitably store all trash and rubbish in the Building or permit elsewhere on the Property in locations designated by Landlord from time to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articlestime. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.

Prohibited Uses. (a) Tenant will not use, occupy or permit the use or occupancy of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant Tenant’s agents shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit suffer to be committed any action waste upon the Premises. Tenant and Tenant’s agents shall not do or circumstance permit anything to be done in or about the Premises or Common Area which will in any way obstruct or interfere with the rights of any authorized users of the Common Area or occupants of neighboring property, or injure or annoy them. Tenant shall not conduct or permit any auction or sale open to the public to be held or conducted on or about the Premises or Common Area. Tenant and Tenant’s agents shall not use or allow the Premises to be used for any unlawful, immoral or hazardous purpose or any purpose not permitted by this Lease, nor shall Tenant or Tenant’s agents cause, maintain, or permit any nuisance in, on or about the Premises, . Tenant and Tenant’s agents shall not do or permit anything to be done in or about the Premises or Common Area nor bring or keep anything therein whichin the Premises or Common Area which will in any way increase the rate of any insurance upon the Premises or Common Area or any part thereof or any of its contents, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premisesthe Premises or Common Area or any part thereof or any of its contents, nor shall Tenant or Tenant’s agents keep, use or sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at upon the Premises or Common Area or any part thereof or any of its contents is increased because of Tenant’s sole particular use of the Premises or that of Tenant’s agents, Tenant shall pay, as Additional Rent, the full cost and expense, promptly comply with all Legal Requirements now of such increase; provided however this provision shall in force no event be deemed to constitute a waiver of Landlord’s right to declare a default hereunder by reason of the act or which may hereafter be in force and with the requirements conduct of Tenant or Tenant’s agents causing such increase or of any board other rights or remedies of fire underwriters Landlord in connection therewith. Tenant and Tenant’s agents shall not place any loads upon the floor, walls or other similar body now ceiling of the Premises which would endanger the Premises or hereafter constituted relating to or affecting the use or occupancy of all structural elements thereof, nor place any harmful liquids in the drainage system of the Premises, excluding such structural changes as do not relate . No waste materials or refuse shall be dumped upon or permitted to or affect the use or occupancy remain upon any part of the PremisesPremises or Common Area except in enclosed trash containers designated for that purpose by Landlord. No materials, supplies, equipment, finished products (or semi-finished products), raw materials, or as are not related other articles of any nature shall be stored upon, or be permitted to or afforded by Tenant’s improvements or actsremain on, any portion of the Common Area.

Prohibited Uses. (a) Tenant will TENANT shall not use said Premises for any use other than that which is specified in the Lease, and shall not permit them to be used, for any other purpose, without first obtaining the written consent of LANDLORD. TENANT shall promptly and continuously comply with all laws, orders, and regulations of the State, County and City, affecting the use, occupy or permit the use or occupancy of any occupation, safety and cleanliness of the Premises for and the equipment of TENANT . TENANT may not display or sell items or allow carts, portable signs, devices or any purpose other objects to be stored or to remain outside the exterior walls and permanent doorways of the Premises. TENANT further agrees not to install any exterior lighting, amplifiers or similar devices or use in or about the Premises any manner advertising medium which is may be heard or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or seen outside the Premises, including but not limited to zoningsuch as flashing lights, environmental and utility conservation matters (hereinafter “Legal Requirements”)searchlights, (ii) covenantsloudspeakers, conditions, phonographs or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant radio broadcasts. TENANT shall not keep do or permit anything to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance done in or about any of the Premises, Premises nor bring or keep anything therein which, directly which will in any way increase the existing rate or indirectly, would affect any fire or might cause a cancellation other insurance upon the Premises or the Building or any of any insurance policy covering such Premisesits contents, nor shall Tenant TENANT sell or permit any articles to be kept, used or sold in or about any of the Premises any articles Premises, which may be prohibited by a standard form policy of fire insurance. If LANDLORD’S insurance unless Tenant provides additional insurance coverage extending protection premium is increased as a result of TENANT ’S business operation, TENANT agrees to cover all risks associated with those articles. (f) Tenant shallpay said increase. In the event Premises represent a section of a larger Building, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now TENANT shall not do or permit anything to be done in force or about the Premises which may hereafter be will in force and any way obstruct or interfere with the requirements rights of other tenants or occupants of the Building of which the Premises may be a part or injure or annoy them, or use or allow the Premises to be used for any unlawful or objectionable purpose, nor shall TENANT cause, maintain or permit any nuisance in, on, or about the Premises. TENANT shall not commit or allow to be committed any waste in or upon Premises. TENANT shall keep the Premises in a clean and wholesome condition, free of any board of fire underwriters objectionable noises, odors or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or actsnuisances.

Prohibited Uses. (a) Tenant will shall not use, occupy or suffer or permit the use of, or occupancy of suffer or permit anything to be done in or anything to be brought into or kept in, the Demised Premises or any part thereof (i) which would violate any of the Premises for any purpose or in any manner which is or may becovenants, directly or indirectlyagreements, in violation terms, provisions and conditions of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”)this Lease, (ii) covenants, conditions, for any unlawful purposes or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Leaseany unlawful manner, or (iii) insurance requirements. which, in the reasonable judgment of Landlord shall in any way (a) impair or tend to impair the appearance or reputation of the Building, (b) Tenant shall not keep impair or permit interfere with or tend to be kept any substance in, impair or conduct or permit to be conducted any operation from, interfere with any of the Premises which is not reasonably consistent Building services or the proper and economic heating, cleaning, air conditioning or other servicing of the Building or with the Permitted Use for such Premises and which might emit offensive odors or conditionsuse of any of the other areas of the Building, or make undue noise or create undue vibrations. (c) Tenant shall not commit occasion discomfort, inconvenience or permit to remain any waste annoyance to any of the other tenants or occupants of the Building, whether through the transmission of noise or odors or vibrations or dust or otherwise. Without limiting the generality of the foregoing, no food shall be prepared or served for consumption by the general public on or about the Demised Premises; no intoxicating liquors or alcoholic beverages shall be sold or otherwise served for consumption by the general public on or about the Demised Premises; no lottery tickets (even where the sale of such tickets is not illegal) shall be sold and no gambling, betting or wagering shall otherwise be permitted on or about the Demised Premises; no loitering shall be permitted on or about the Demised Premises; and no loading or unloading of supplies or other material to or from the Demised Premises shall be permitted on the Land except at times (excluding Business Days from 7:00 to 9:30 a.m. and from 4:00 to 6:00 p.m.) and in locations to be reasonably designated by Landlord, except for the freight elevator described in Section 7.4, which Tenant may use at any time. The Demised Premises shall be maintained in a sanitary condition. Tenant shall suitably store all trash and rubbish in the Demised Premises or other locations designated by Landlord from time to time. All laboratory waste, Hazardous Materials and medical waste must be disposed of in compliance with Section 5.3. Tenant specifically agrees that its indemnification obligations pursuant to Section 13.2 shall extend to any claim arising from the consumption of intoxicating liquors or alcoholic beverages on or about the Demised Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.

Prohibited Uses. (a) Tenant will shall not use, occupy use or permit the use of the Demised Premises or occupancy any part thereof which would violate any of the provisions of this Lease, or for any purpose which is in violation of Applicable Laws, or in any unlawful manner, or in violation of the Certificate of Occupancy for the Demised Premises or the Building, and Tenant shall not suffer or permit the Demised Premises or any part thereof to be used in any manner, or anything to be done therein or anything to be brought into or kept therein which, in the reasonable judgement of Landlord, shall in any way impair the character, reputation or appearance of the Building as a first rate office building, impair or interfere with any of the Building services or the proper and economic heating, cleaning, air-conditioning or other servicing of the Building or the Demised Premises, or impair or interfere with the use of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation other areas of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditionsBuilding by, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on occasion unreasonable discomfort, inconvenience or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation fromannoyance to, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors other tenants or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any occupants of the Premises. (d) Building. Tenant shall not install any electrical or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls other equipment of any buildings located on such Premiseskind which, or adversely affect in the mechanicalreasonable judgement of Landlord, plumbing or electrical systems of might cause any such buildingsimpairment, interference, discomfort, inconvenience or affect annoyance to Landlord or any other tenant in the structural integrity of any such buildings in any way. (e) Building, Tenant shall not commit make void or permit to be committed voidable any action fire or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any liability insurance policy covering such Premises, then in force with respect to the Building nor shall Tenant sell make unobtainable from reputable insurance companies authorized to do business in New York State any fire or casualty insurance with extended coverage or liability, elevator, boiler or other insurance at standard rates. Tenant shall not suffer or permit the Demised Premises to be keptused in a manner which would constitute a public or private nuisance or unreasonably impair, used in the sole reasonable opinion of Landlord, the appearance, character or sold in or about any reputation of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articlesBuilding. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.

Prohibited Uses. (a) Tenant will shall not use, occupy do or permit the use or occupancy of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit anything to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance done in or about any of the Premises, Premises nor bring or keep anything therein whichwhich will in any way increase the existing rate or affect any fire or other insurance on the Building or any of its contents, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premisesthe Building or any part thereof or any of its contents, nor shall Tenant sell or permit to be kept, used or sold sold, in or about any of the Premises Premises, any articles or substances, inflammable or otherwise, which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articlesthe insurance. (fb) Tenant shallshall not do or permit anything to be done in or about the Premises which will in any way obstruct space or interfere with the rights of other tenants or occupants of the Building or injury or annoy them or use or allow the Premises to be used for any unlawful or objectionable purpose, nor shall Tenant cause, maintain or permit any nuisance in or about the Premises. Tenant shall not commit or suffer to be committed any waste in or upon the Premises. (c) Tenant shall not use the Premises or permit anything to be done in or about the Premises which will in any way conflict with any law, statute, ordinance or governmental rule or regulation or requirement of duly constituted public authorities now in force or which may hereafter be enacted or promulgated. Tenant shall at Tenant’s its sole cost and expense, expense promptly comply with all Legal Requirements laws, statutes, ordinances and governmental rules, regulations or requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premisescondition, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, excluding structural changes not relating to or as are affecting the condition, use or occupancy of the Premises not related to or afforded by Tenant’s 's improvements or acts. The judgment of any court of competent jurisdiction or the admission of Tenant in any action against Tenant, whether Landlord be a party thereto or not, that Tenant has violated any law, statute, ordinance or governmental rule, regulation or requirement shall be conclusive of the fact as between Landlord and Tenant.

Prohibited Uses. In addition to the use restrictions set forth elsewhere in this Lease, Tenant will not: (a) Tenant will permit in or from the Premises any objectionable odor or noise or any nuisance, except for such odor and/or noise that is reasonable and customary for the operation of a brewery; (b) commit waste; (c) permit the Premises to be used for an auction, fire, bankruptcy or going out of business sale; (d) cease active conduct of Tenant’s business in the Premises for more than thirty (30) days without the prior written consent of Landlord, not useto be unreasonably withheld; (e) use any portion of the Premises as residential rental property; (f) engage in any trade or business consisting of the operation of, occupy or otherwise permit the use or occupancy of any portion of the Premises for, any private or commercial golf course, country club, massage parlor, hot tub facility, suntan facility, racetrack or other facility used for gambling, or any store the principal business of which is the retail carry-out sale of alcoholic beverages for consumption off premises, excluding the sale of bulk beverages brewed or otherwise produced on the Premises; (g) permit the development or holding of intangibles for sale or license; or (h) use, store, manufacture, dispose of or discharge any hazardous materials in, at or from the Premises. As used in this section, “hazardous materials” means any substances or materials the use, transportation, storage, manufacture or disposal of which is governed by laws treating the quality of the environment, and will include asbestos and petroleum products. Use of hazardous materials in accordance with law in amounts appropriate to and necessary for the use of the Premises permitted by this Lease will be permitted. Accordingly, Tenant agrees to indemnify Landlord and hold it harmless for any purpose or in any manner which is or may becosts and/or liabilities including without limitation reasonable attorneys’ fees, directly or indirectly, in violation arising from Tenant’s release of any hazardous materials or failure to comply with applicable environmental laws. Tenant first shall obtain the written consent of Landlord prior to (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances expanding the area of any governmental authority in any way applicable to Tenant or the Premises associated with the sale of alcoholic beverages for off-premises consumption beyond 5% of the total square footage of the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such expanding Tenant’s sales of alcoholic beverages for off-premises consumption beyond 10% of total sales from the Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Leaseduring any calendar year, or (iii) insurance requirements. (b) selling lottery tickets on the Premises. Consent is subject to Landlord’s sole and absolute discretion. Tenant shall not keep or permit to be kept (i) carry on any substance in, or conduct or permit to be conducted activity that could cause any operation from, any part of the Premises or the Building to be “tax-exempt use property” (as that term is used in Section 168(h) of the Internal Revenue Code) or “residential rental property” (as defined in Section 168 of the Internal Revenue Code) or (ii) use the Premises or the Building to engage in the operation of any private or commercial golf course, country club, massage parlor, hot tub facility, suntan facility, racetrack, off-track betting facility or other facility used for gambling; or any store the principal business of which is not reasonably consistent with the Permitted Use retail carry-out sale of alcoholic beverages for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premisesconsumption off premises, excluding such structural changes as do not relate to the sale of bulk beverages brewed or affect the use or occupancy of otherwise produced on the Premises, or as fireworks; farming (within the meaning of Section 2032A(e)(5)(A) or (B) of the Code and the related Treasury Regulations), or any one or more of the following activities: shooting gallery, adult bookstore or facility selling or displaying obscene or pornographic books, literature or videotapes or movies (materials shall be considered “adult”, “obscene” and “pornographic” for such purposes if the same are not related generally available for sale, rental or display to human persons under 18 years old because they explicitly deal with or afforded depict human sexuality or are otherwise intended to appeal to prurient interests); any establishment that provides striptease or topless entertainment; bingo or similar games of chance (excluding such games conducted by Tenant’s improvements a charitable organization as part of a fundraising activity); video game or actsamusement arcade, except as an incidental part of another primary business; pawn shops or establishments, a primary business or service of which is cashing checks; any marijuana dispensary, so-called “head shop” or store that sells bongs, coke spoons, r▇▇▇▇ clips or other drug paraphernalia; a flea market; any political campaign or party office; or any illegal use (collectively, (i) and (ii) in this paragraph, and all other prohibited uses set forth in the preceding paragraph of this Section 22, are referred to as the “Use Restrictions”). Any violation of the Use Restrictions shall constitute an event of default of this Lease and shall permit Landlord to immediately terminate this Lease to the extent permitted by applicable law, including any minimum notice requirements thereof.

Prohibited Uses. (a) Tenant will shall not usecause, occupy suffer or permit the Premises or any part thereof to be used at any time during the Term for any of the following businesses or activities: any type of business or business practice which would, in the reasonable opinion of Landlord, tend to lower the character or image of the Project or any portion thereof; any use which in any way contravenes any restrictive covenants in leases granted by Landlord after the date hereof; Tenant covenants and agrees that it will not carry on in the Premises any business which will in any way place Landlord in breach of any such restrictive covenants and Tenant will indemnify and save Landlord harmless from and against all actions, claims, demands and costs with respect thereto; this subsection (ii) shall not be interpreted to prevent Tenant from carrying on in the Premises any business to the extent expressly permitted pursuant to section 8.1 hereof; or occupancy any business or activity not in compliance with all Laws. The inclusion of the foregoing provisions of this section 8.10 shall not be deemed to be a representation or warranty of Landlord that any of the foregoing activities will not be authorized by Landlord to be conducted on any part of the Project. If, in the opinion of Landlord, Tenant is in breach of any of the Premises for any purpose or provisions of this section 8.10, Tenant shall immediately discontinue such use upon Landlord's written request. Any restrictive covenants granted by the Landlord shall not restrict the Tenant from carrying on its business as contemplated herein and shall not result in any manner which is or may be, directly or indirectly, increase in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable charges to the Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject pursuant to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.

Prohibited Uses. (a) Tenant will not useThe uses prohibited under this Lease shall include, occupy or permit the without limitation, use or occupancy of any of the Premises or a portion thereof for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisionsretail or restaurant uses, orderexcept for approved kitchens, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates cafeterias and pantries (not serving the general public); or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditionsradio and/or television stations, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) other similar media outlets. Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of allow occupancy density for the Premises which is greater than permitted by Applicable Laws. Tenant further covenants and agrees that it shall not reasonably use, or suffer or permit any person or persons to use, the Premises or any part thereof in violation of Applicable Laws or for any use or purpose contrary to the provisions of the Rules and Regulations (the rules and regulations, attached hereto as Exhibit D, are, the “Existing Rules and Regulations,” and together with such additional rules and regulations as Landlord may promulgate in accordance with the terms of this Lease, and as the Existing Rules and Regulations and additional rules may be amended or supplemented in accordance with the terms of this Lease, the “Rules and Regulations”). Landlord shall have the right to amend, supplement, and add new commercially reasonable rules and regulations to the Rules and Regulations at any time during the Lease Term, and such amendments, supplements, and new rules and regulations shall be deemed Rules and Regulations hereunder; provided, however, that notwithstanding anything to the contrary in this Lease, the Rules and Regulations shall be enforceable against Tenant only to the extent that (a) they are reasonable and consistent with the Permitted Use for such Premises Class A Standard; (b) they are consistent with Landlord’s Obligations to Minimize Tenant Interference and which might emit offensive odors do not otherwise materially increase Tenant’s obligations or conditions, or make undue noise or create undue vibrations. materially decrease Tenant’s rights under this Lease; (c) Tenant shall not commit or permit to remain any waste to any has been provided notice in writing of the Premises. such Rules and Regulations; and (d) the Rules and Regulations are applied and enforced in a reasonable, equitable and non-arbitrary manner. Tenant shall not install do or permit anything to remain any improvements to any of be done in or about the Premises which exceed will unreasonably interfere with the structural loads rights of floors other tenants or walls occupants of any buildings located on such Premisesthe Building, or adversely affect injure them or use or allow the mechanical, plumbing Premises or electrical systems any of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit Tenant’s Off-Premises Equipment to be committed used for any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premisesunlawful purpose, nor shall Tenant sell cause, maintain or permit to be keptany nuisance in, used or sold in on or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.

Prohibited Uses. (a) Notwithstanding any other provision of this Lease, Tenant will shall not useuse the Premises or the Building, occupy or any part thereof, or suffer or permit the use or occupancy of the Premises or the Building or any part thereof by any of the Premises Tenant Parties (hereinafter defined) (i) in a manner which would violate any of the covenants, agreements, terms, provisions and conditions of this Lease or otherwise applicable to or binding upon the Premises; (ii) for any purpose unlawful purposes or in any unlawful manner; (iii) in a manner which, in the reasonable judgment of Landlord shall (a) impair the appearance or reputation of the Building; (b) impair, interfere with or otherwise diminish the quality of any of the Building services or the proper and economic heating, cleaning, ventilating, air conditioning or other servicing of the Building or Premises; or (c) cause harmful air emissions or any unusual or other objectionable odors, noises or emissions to emanate from the Premises; (iv) in a manner which is inconsistent with the operation and/or maintenance of the Building as a first-class office and laboratory building; (v) for any fermentation processes except in the ordinary course of Tenant’s business and then only if adequately vented in Landlord’s reasonable judgment (it being understood and agreed that in no event shall there be fermentation for the purpose of creating alcoholic beverages for human consumption); (vi) to operate a vivarium in excess of 3,500 square feet; or may be(vii) in a manner which shall increase such insurance rates on the Building or on property located therein over that applicable when Tenant first took occupancy of the Premises hereunder. Notwithstanding any other provision herein to the contrary, directly Tenant shall be responsible for all liabilities, costs and expenses arising from or indirectlyin connection with the compliance of the Premises with the Americans with Disabilities Act, in violation of 42 U.S.C. § 12101, et seq., and any state and local accessibility laws, codes, ordinances and rules (i) judicial decisionscollectively, orderand together with regulations promulgated pursuant thereto, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal RequirementsADA”), (ii) covenantsand Tenant shall defend, conditions, or restrictions applicable indemnify and hold Landlord and the Landlord Parties harmless from and against any Claims arising from any such failure the Premises to such Premises and appearing of record comply with the ADA. Landlord agrees that Landlord’s Base Building Work shall be constructed in conformance with the office ADA. In the event Landlord’s Base Building Work is not constructed in conformance with the ADA in effect as of the county recorder date Landlord commences the Landlord’s Base Building Work, and provided Tenant provides Landlord written notice thereof within three (3) months after the Commencement Date, and provided Landlord does not dispute Tenant’s determination of the county in non-compliance, Landlord shall, as Tenant’s sole and exclusive remedy, address any such non-compliance of Landlord’s Base Building Work (and expressly not any Tenant Improvements or any modifications or alterations of Landlord’s Base Building Work that are made necessary as a result of Tenant Improvements, which such Premises modifications or alterations are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirementsTenant’s sole responsibility and cost). (b) With respect to the use and occupancy of the Premises and the Common Areas, Tenant shall not keep will not: (i) place or permit to maintain any signage (except as may be kept permitted by Section 12 below), Trash (hereinafter defined) or other articles in any substance investibule or entry of the Premises, on the footwalks or corridors adjacent thereto or elsewhere on the exterior of the Premises, nor obstruct any driveway, corridor, footwalk, Parking Area, or any Common Areas; (ii) permit undue accumulations of or burn garbage, trash, rubbish or other refuse (collectively, “Trash”) within or without the Premises; (iii) permit the parking of vehicles so as to interfere with the use of any driveway, corridor, footwalk, or parking area; (iv) receive or ship articles of any kind outside of those areas reasonably designated by Landlord; (v) conduct or permit to be conducted any operation fromauction, going out of business sale, bankruptcy sale (unless directed by court order), or other similar type sale in or connected with the Premises; (vi) use the name of Landlord, or any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors Landlord’s affiliates or conditionssubsidiaries in any publicity, promotion, trailer, press release, advertising, printed, or make undue noise or create undue vibrations. display materials without Landlord’s prior written consent (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenantwithheld in Landlord’s sole cost and expensediscretion); (vii) except in connection with any vivarium, promptly comply permit any animals other than service animals in the Building; or (viii) except in connection with all Legal Requirements now Alterations (hereinafter defined) approved by Landlord, cause or permit any hole to be drilled or made in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all part of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.Building

Prohibited Uses. (a) Tenant will further covenants and agrees that Tenant shall not use, occupy or suffer or permit any person or persons to use, the Premises or any part thereof for any use or occupancy of any purpose contrary to the provisions of the Premises for any purpose Rules and Regulations set forth in Exhibit D, attached hereto, or in any manner which is or may be, directly or indirectly, in violation of the laws of the United States of America, the State of California, or the ordinances, regulations or requirements of the local municipal or county governing body or other lawful authorities having jurisdiction over the Project, including, without limitation, any (i) judicial decisionssuch laws, orderordinances, injunctionsregulations or requirements relating to hazardous materials or substances, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates as those terms are defined by applicable laws now or ordinances of any governmental authority hereafter in effect. Tenant shall not do or permit anything to be done in or about the Premises which will in any way applicable to Tenant unreasonably obstruct or interfere with the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditionsrights of other tenants or occupants of the Building, or restrictions applicable to such unreasonably injure or annoy them or use or allow the Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept used for any substance in, unlawful or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premisesobjectionable purpose, nor shall Tenant sell cause, maintain or permit any nuisance (including, without limitation, foul or noxious odors in connection with the operation of the Cafeteria)(the parties hereby acknowledge and agree that any normal or reasonable food odors shall not be deemed to be keptfoul or noxious) in, used or sold in on or about any the Premises. Notwithstanding the foregoing, (i) if occupants of the Premises building reasonably complain of excessive cooking odors emanating from the Premises, or (ii) if a government entity notifies Tenant or Landlord of a violation of any articles federal, state or local law as a result of such cooking odors emanating from the Premises, the parties shall notify each other in writing (which may be prohibited by writing shall include a standard form policy copy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) the government violation notice), Tenant shall, at within fifteen (15) days after Tenant’s sole cost receipt of a government notice or Landlord’s written notice, deliver a written proposal to Landlord outlining a solution to the odor problem for Landlord’s reasonable approval (and expense, promptly for the approval of any applicable governmental agency that has appeal rights). Tenant shall implement the Landlord approved solution within sixty (60) days after Tenant’s receipt of Landlord’s written notice of approval. Tenant’s failure to strictly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of this provision shall be a default under the Lease. Further, if Tenant fails to address the issue of odors emanating from the Premises within the time frames set forth herein the Landlord may elect in Landlord’s sole discretion, to develop and implement its own reasonable odor control plan in the Premises and Tenant shall reimburse Landlord for the actual and reasonable out of pocket cost of developing and implementing the Landlord plan, which costs shall include a five percent (5%) supervision fee. Landlord shall in no event enter into any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premisessuch easements, excluding such structural changes as do not relate to or affect the use or occupancy of the Premisescovenants, or as are not related to or afforded by conditions and restrictions that reduce Tenant’s improvements rights or actsincrease Tenant’s obligations in more than a di minimis amount as set forth in this Lease.

Prohibited Uses. The uses prohibited under this Lease shall include, without limitation, use of the Premises or a portion thereof for (ai) offices of any agency or bureau of the United States or any state or political subdivision thereof; (ii) offices or agencies of any foreign governmental or political subdivision thereof; (iii) offices of any health care professionals or service organization; (iv) schools or other training facilities which are not ancillary to corporate, executive or professional office use; (v) retail use or the operation of any restaurant offering services to the public; (vi) a data or call center; or (vii) communications firms such as radio and/or television stations. Tenant will further covenants and agrees that Tenant shall not use, occupy or suffer or permit any person or persons to use, the Premises or any part thereof for any use or occupancy of any purpose contrary to the provisions of the Premises for any purpose Rules and Regulations set forth in Exhibit D, attached hereto, or in any manner which is or may be, directly or indirectly, in violation of the laws of the United States of America, the State of California, or the ordinances, regulations or requirements of the local municipal or county governing body or other lawful authorities having jurisdiction over the Project) including, without limitation, any (i) judicial decisionssuch laws, orderordinances, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates regulations or ordinances of any governmental authority requirements relating to Hazardous Substances. Tenant shall not do or permit anything to be done in or about the Premises which will in any way applicable damage the reputation of the Project or obstruct or interfere with the rights of other tenants or occupants of the Building, or injure or annoy them or use or allow the Premises to be used for any unlawful purpose, nor shall Tenant cause, maintain or permit any nuisance in, on or about the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) . Tenant shall comply with all recorded covenants, conditions, and restrictions now or restrictions applicable to such Premises and appearing of record hereafter affecting the Project. Except for small quantities customarily used in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Leasebusiness offices, or (iii) insurance requirements. (b) Tenant shall not keep cause or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit Hazardous Substance to be kept, used maintained, used, stored, produced, generated or sold disposed of (into the sewage or waste disposal system or otherwise) on or in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at or Tenant’s sole cost agents, employees, contractors, invitees, assignees or sublessees, without first obtaining Landlord’s written consent. Tenant shall immediately notify, and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by shall direct Tenant’s improvements or acts.agents,

Prohibited Uses. (a) Notwithstanding any other provision of this Lease, Tenant will shall not use, occupy or suffer or permit the use or occupancy of, or suffer or permit anything to be done in or anything to be brought into or kept in or about the premises or the Building or any part thereof (including, without limitation, any materials appliances or equipment used in the construction or other preparation of the premises and furniture and carpeting): (i) which would violate any of the covenants, agreements, terms, provisions and conditions of this Lease or otherwise applicable to or binding upon the Premises that are in effect as of the date of this Lease and of which Tenant has received notice prior to the execution of this Lease, including, without limitation, those covenants affecting the Franklin Industrial Park ("Park Covenants") and, subject to Article 23(h), any future rules and regulations which may be issued pursuant to the Park Covenants, (ii) for any unlawful purposes or in any unlawful manner; or (iii) which, in the reasonable judgment of Landlord shall in any way impair, interfere with or otherwise diminish the quality of any of the Building services or the proper and economic heating, cleaning, ventilating, air conditioning or other servicing of the Building; or premises, or with the use or occupancy of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation other areas of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditionsBuilding, or restrictions applicable occasion discomfort, inconvenience or annoyance, or injury or damage to such Premises and appearing of record in the office any occupants of the county recorder premises or other tenants or occupants of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Building. Tenant shall not install or permit to remain use any improvements to any of the Premises which exceed the structural loads of floors electrical or walls other equipment of any buildings located on such Premiseskind which, or adversely affect in the mechanicalreasonable judgment of Landlord, plumbing or electrical systems of might cause any such buildingsimpairment, interference, discomfort, inconvenience, annoyance or affect injury. Notwithstanding the structural integrity foregoing terms of any such buildings in any way. (e) this Article 5.2, Tenant shall not commit be deemed to have suffered or permit to be committed any action permitted an act or circumstance in or about any omission: (x) which occurs outside of the Premises, nor bring unless such act or keep anything therein which, directly omission was by Tenant or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall those for whom Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premisesis legally responsible, or as are not related to (y) by Landlord or afforded by Tenant’s improvements or actsthose for whom Landlord is legally responsible.

Prohibited Uses. (a) Tenant will not use, occupy or permit the use or occupancy of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant Tenant's agents shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit suffer to be committed any action waste upon the Premises. Tenant and Tenant's agents shall not do or circumstance permit anything to be done in or about the Premises or Common Area which will in any way obstruct or interfere with the rights of any other tenants of the Building, other authorized users of the Common Area, or occupants of neighboring property, or injure or annoy them. Tenant shall not conduct or permit any auction or sale open to the public to be held or conducted on or about the Premises or Common Area. Tenant and Tenant's agents shall not use or allow the Premises to be used for any unlawful, immoral or hazardous purpose or any purpose not permitted by this Lease, nor shall Tenant or Tenant's agents cause, maintain, or permit any nuisance in, on or about the Premises, . Tenant and Tenant's agents shall not do or permit anything to be done in or about the Premises nor bring or keep anything therein whichin the Premises which will in any way increase the rate of any insurance upon any portion of the Project or any of its contents, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premisesany portion of the Project or any of its contents, nor shall Tenant or Tenant's agents keep, use or sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with insurance. In the requirements event the rate of any board insurance upon any portion of fire underwriters the Project or any of its contents is increased because of Tenant's particular use of the Premises or that of Tenant's agents, Tenant shall pay, as Additional Rent, the full cost of such increase; provided, however this provision shall in no event be deemed to constitute a waiver of Landlord's right to declare a default hereunder by reason of the act or conduct of Tenant or Tenant's agents causing such increase or of any other similar body now rights or hereafter constituted relating to remedies of Landlord in connection therewith. Tenant and Tenant's agents shall not place any loads upon the floor, walls or affecting ceiling of the use Premises which would endanger the Building or occupancy of all the structural elements thereof or of the Premises, excluding such structural changes as do not relate to or affect nor place any harmful liquids in the use or occupancy drainage system of the PremisesBuilding or Common Area. No waste materials or refuse shall be dumped upon or permitted to remain upon any part of the Project except in enclosed trash containers designated for that purpose by Landlord. No materials, supplies, equipment, finished products (or semi-finished products), raw materials, or as are not related other articles of any nature shall be stored upon, or be permitted to or afforded by Tenant’s improvements or actsremain on, any portion of the Project outside the Premises.

Prohibited Uses. Tenant further covenants and agrees that Tenant shall not use, or suffer or permit any person or persons to use, the Premises or any part thereof for any use or purpose in violation of Legal Requirements. Tenant will faithfully observe and comply with (i) the Building Rules and Regulations annexed hereto as Exhibit D-1 and (ii) the “Green Lease” provisions annexed hereto as Exhibit D-2 (collectively, the “Rules and Regulations”), and further reasonable Rules and Regulations as Landlord hereafter at any time or from time to time may make and communicate in writing to Tenant, which in the reasonable judgment of Landlord shall be necessary for the reputation, safety, care or appearance of the Building, the Project or the preservation of good order therein, or the operation or maintenance of the Building, the Project or the equipment thereof, provided, however, that in the case of any conflict between the provisions of this Lease and any such future rules and regulations, the provisions of this Lease shall control. Nothing contained in this Lease shall be construed to impose upon Landlord any duty or obligation to enforce the Rules and Regulations or the terms, covenants or conditions in any other lease as against any other tenant and Landlord shall not be liable to Tenant for violation of the same by any other tenant, its servants, employees, agents, contractors, visitors, invitees or licensees. Tenant shall not do or permit anything to be done in or about the Premises which will in any way (a) Tenant will not usedamage the reputation of the Project; (b) impair, occupy interfere with or permit otherwise diminish the use or occupancy quality of any of the Building services or the proper and economic heating, cleaning, ventilating, air conditioning or other servicing of the Building or Premises, or the use of any of the Common Areas; (c) obstruct or interfere with the rights of other tenants or occupants of the Building, or injure or annoy them; (d) use or allow the Premises to be used for any purpose improper, unlawful or in objectionable purpose; (e) cause harmful air emissions or laboratory odors or objectionable odors, noises or emissions to emanate from the Premises; (f) increase such insurance rates on the Building or on property located therein over that applicable when Tenant first took occupancy of the Premises hereunder; or (g) cause, maintain or permit any manner which is nuisance in, on or may beabout the Premises. Furthermore, directly or indirectly, in violation of any Tenant shall not (i) judicial decisionsplace or maintain any garbage, ordertrash, injunctionsrubbish or other refuse (collectively, writs“Trash”), statutes, rulings, rules, regulations, promulgations, directives, permits, certificates signage (except as may be permitted by Article 23 below) or ordinances of any governmental authority other articles in any way applicable to Tenant vestibule or entry of the Premises, including but not limited to zoningon the footwalks or corridors adjacent thereto or elsewhere on the exterior of the Premises, environmental and utility conservation matters (hereinafter “Legal Requirements”)nor obstruct any driveway, corridor, footwalk, parking area, mall or any other Common Areas; (ii) covenants, conditions, permit undue accumulations of or restrictions applicable to such Premises and appearing of record in burn Trash within or without the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or Premises; (iii) insurance requirements. (b) Tenant shall not keep or permit the parking of vehicles so as to be kept interfere with the use of any substance indriveway, corridor, footwalk, parking area, or other Common Areas; (iv) receive or ship articles of any kind outside of those areas reasonably designated by Landlord; (v) conduct or permit to be conducted any operation fromauction, going out of business sale, bankruptcy sale (unless directed by court order), or other similar type sale in or connected with the Premises; or (vi) permit or keep any animals other than trained certified service animals in the Building. Tenant shall comply with, and Tenant’s rights and obligations under the Lease and T▇▇▇▇▇’s use of the Premises which is not reasonably consistent with shall be subject and subordinate to, all governmental permits and approvals affecting the Permitted Use for such Premises Project and which might emit offensive odors or all recorded easements, covenants, conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body restrictions now or hereafter constituted relating to or affecting the use or occupancy of all of the PremisesProject, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or actsincluding any Underlying Documents.

Prohibited Uses. (a) Tenant will shall not use, occupy or suffer or permit the use of, or occupancy of suffer or permit anything to be done in or anything to be brought into or kept in, the Demised Premises or any part thereof (i) which would violate any of the Premises for any purpose or in any manner which is or may becovenants, directly or indirectlyagreements, in violation terms, provisions and conditions of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”)this Lease, (ii) covenants, conditions, for any unlawful purposes or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Leaseany unlawful manner, or (iii) insurance requirements. which, in the reasonable judgment of Landlord shall in any way (a) impair or tend to impair the appearance or reputation of the Building, (b) Tenant shall not keep impair or permit interfere with or tend to be kept any substance in, impair or conduct or permit to be conducted any operation from, interfere with any of the Premises which is not reasonably consistent Building services or the proper and economic heating, cleaning, air conditioning or other servicing of the Building or with the Permitted Use for such Premises and which might emit offensive odors or conditionsuse of any of the other areas of the Building, or make undue noise or create undue vibrations. (c) Tenant shall not commit occasion discomfort, inconvenience or permit to remain any waste annoyance to any of the other tenants or occupants of the Building through the transmission of noise, odors, vibrations, dust, fumes or other emissions perceptible outside the Demised Premises. . Without limiting the generality of the foregoing, no food shall be prepared or served for consumption by the general public on or about the Demised Premises; no intoxicating liquors or alcoholic beverages shall be sold or otherwise served for consumption by the general public on or about the Demised Premises; no lottery tickets (deven where the sale of such tickets is not illegal) shall be sold and no gambling, betting or wagering shall otherwise be permitted on or about the Demised Premises; no loitering shall be permitted on or about the Demised Premises; and no loading or unloading of supplies or other material to or from the Demised Premises shall be permitted on the Land except at times and in locations to be designated by Landlord. Tenant shall not install or permit to remain any improvements to any maintain the Demised Premises in a sanitary condition, free of rodents and vermin, and shall suitably store all trash and rubbish in the Demised Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating locations designated by Landlord from time to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or actstime.

Prohibited Uses. (a) Tenant will Sublessee shall not use, occupy or suffer or permit the use of, or occupancy of suffer or permit anything to be done in the Sublease Premises or the Building or any part thereof (i) which would violate any of the Premises for any purpose or in any manner which is or may becovenants, directly or indirectlyagreements, in violation terms, provisions and conditions of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”)this Sublease, (ii) covenants, conditions, for any unlawful purposes or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Leaseany unlawful manner, or (iii) insurance requirements. which, in the reasonable judgment of Sublessor or Landlord shall in any way (a) impair or tend to impair the appearance or reputation of the Building, (b) Tenant shall not keep impair or permit interfere with or tend to be kept any substance in, impair or conduct or permit to be conducted any operation from, interfere with any of the Premises which is not reasonably consistent with Building services or the Permitted Use for such Premises proper and which might emit offensive odors economic heating, cleaning, air conditioning or conditionsother servicing of the Building, or make undue noise or create undue vibrations. (c) Tenant shall not commit occasion discomfort, inconvenience or permit to remain any waste annoyance to any of the Premises. (d) Tenant shall not install other tenants or permit to remain any improvements to any occupants of the Building, whether through the transmission of noise or odors or otherwise. Without limiting the generality of the foregoing, no food (except in connection with customary office vending machines, coffee service facilities and lunch room facilities set forth on the Complete Plans or other plans approved by Sublessor, provided such machines and facilities are used for and by occupants of the Sublease Premises which exceed only and their guests and further provided Sublessee pays any resulting increased costs pursuant to Section 13.8 and the structural loads other applicable provisions of floors this Sublease) shall be prepared or walls served for public or commercial consumption on or about the Sublease Premises; no intoxicating liquors or alcoholic beverages shall be sold or otherwise served to the general public on or about the Sublease Premises; no lottery tickets (even where the sale of such tickets is not illegal) shall be sold and no gambling, betting or wagering shall otherwise be permitted on or about the Sublease Premises; no combustible materials (except as disclosed to and approved by Sublessor) shall be stored or warehoused; no loitering shall be permitted on or about the Sublease Premises; and no loading or unloading of supplies or other material to or from the Sublease Premises shall be permitted on the Lot except during such hours as the Building is customarily open for business. The Sublease Premises shall be maintained by Sublessee in a sanitary condition, kept free from odors and kept free from rodents and laboratory animals of any buildings located on such Premiseskind and vermin. Sublessee shall be responsible for the proper handling and disposal of all its trash, or adversely affect rubbish and other wastes, and for compliance with all local, state and federal laws applicable to the mechanical, plumbing or electrical systems storage and disposal of any such buildings, or affect wastes. Sublessee shall also provide cleaning services to the structural integrity of any such Sublease Premises according to cleaning standards generally prevailing in first class buildings in the City of Boston and in accordance with any waycleaning specifications or rules and regulations promulgated from time to time by Landlord and Sublessor. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or acts.

Prohibited Uses. (a) Tenant will TENANT shall not use said Premises for any use other than that which is specified in the Lease, and shall not permit them to be used, for any other purpose, without first obtaining the written consent of LANDLORD. TENANT shall promptly and continuously comply with all laws, orders, and regulations of the State, County and City, affecting the use, occupy or permit the use or occupancy of any occupation, safety and cleanliness of the Premises for and the equipment of TENANT . TENANT may not display or sell items or allow carts, portable signs, devices or any purpose other objects to be stored or to remain outside the exterior walls and permanent doorways of the Premises. TENANT further agrees not to install any exterior lighting, amplifiers or similar devices or use in or about the Premises any manner advertising medium which is may be heard or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or seen outside the Premises, including but not limited to zoningsuch as flashing lights, environmental and utility conservation matters (hereinafter “Legal Requirements”)searchlights, (ii) covenantsloudspeakers, conditions, phonographs or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant radio broadcasts. TENANT shall not keep do or permit anything to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance done in or about any of the Premises, Premises nor bring or keep anything therein which, directly which will in any way increase the existing rate or indirectly, would affect any fire or might cause a cancellation other insurance upon the Premises or the Building or any of any insurance policy covering such Premisesits contents, nor shall Tenant TENANT sell or permit any articles to be kept, used or sold in or about any of the Premises any articles Premises, which may be prohibited by a standard form policy of fire insurance. If LANDLORD’S insurance unless Tenant provides additional insurance coverage extending protection premium is increased as a result of TENANT ‘S business operation, TENANT agrees to cover all risks associated with those articles. (f) Tenant shallpay said increase. In the event Premises represent a section of a larger Building, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now TENANT shall not do or permit anything to be done in force or about the Premises which may hereafter be will in force and any way obstruct or interfere with the requirements rights of other tenants or occupants of the Building of which the Premises may be a part or injure or annoy them, or use or allow the Premises to be used for any unlawful or objectionable purpose, nor shall TENANT cause, maintain or permit any nuisance in, on, or about the Premises. TENANT shall not commit or allow to be committed any waste in or upon Premises. TENANT shall keep the Premises in a clean and wholesome condition, free of any board of fire underwriters objectionable noises, odors or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or actsnuisances.

Prohibited Uses. (a) Tenant will not use, occupy or permit the use or occupancy of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant Tenant’s agents shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit suffer to be committed any action waste upon the Premises. Tenant and Tenant’s agents shall not do or circumstance permit anything to be done in or about any of the Premises, Building, Project or Common Area which will in any way obstruct or interfere with the rights of any other tenants of the Project, other authorized users of the Common Area, or occupants of neighboring property, or injure or annoy them. Tenant shall not conduct or permit any auction or sale open to the public to be held or conducted on or about the Premises, Building, Project or Common Area. Tenant and Tenant’s agents shall not use or allow the Premises to be used for any unlawful, immoral or hazardous purpose or any purpose not permitted by this Lease, nor shall Tenant or Tenant’s agents cause, maintain, or permit any nuisance in, on or about the Premises, Building, Project or Common Area. Tenant shall not overload existing electrical systems or other mechanical equipment servicing the Building, impair the efficient operation of the sprinkler system or the heating, ventilation or air conditioning equipment within or servicing the Building or damage, overload or corrode the sanitary sewer system. Tenant and Tenant’s agents shall not do or permit anything to be done in or about the Premises nor bring or keep anything therein whichin the Premises which will in any way increase the rate of any insurance upon any portion of the Project or any of its contents, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premisesany portion of the Project or any of its contents, nor shall Tenant or Tenant’s agents keep, use or sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at upon any portion of the Project or any of its contents is increased because of Tenant’s sole particular use of the Premises or that of Tenant’s agents, Tenant shall pay, as Additional Rent, the full cost and expenseof such increase; provided, promptly comply with all Legal Requirements now however this provision shall in force no event be deemed to constitute a waiver of Landlord’s right to declare a default hereunder by reason of the act or which may hereafter be in force and with the requirements conduct of Tenant or Tenant’s agents causing such increase or of any board other rights or remedies of fire underwriters Landlord in connection therewith. Tenant and Tenant’s agents shall not place any loads upon the floor, walls or other similar body now ceiling of the Premises which would endanger the Building or hereafter constituted relating to the structural elements thereof or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect nor place any harmful liquids in the use or occupancy drainage system of the PremisesBuilding or Common Area. No waste materials or refuse shall be dumped upon or permitted to remain upon any part of the Project except in enclosed trash containers designated for that purpose by Landlord. No materials, supplies, equipment, finished products (or semi-finished products), raw materials, or as are not related other articles of any nature shall be stored upon, or be permitted to or afforded by Tenant’s improvements or actsremain on, any portion of the Project outside the Premises.

Prohibited Uses. (a) Tenant will further covenants and agrees that Tenant shall not use, occupy or suffer or permit any person or persons to use, the Premises or any part thereof for any use or purpose in violation of the laws of the United States of America, the State of California, or the ordinances, regulations or requirements of the local municipal or county governing body or other lawful authorities having jurisdiction over the Project) including, without limitation, any such laws, ordinances, regulations or requirements relating to hazardous materials or substances, as those terms are defined by Applicable Laws now or hereafter in effect, or any Underlying Documents. Landlord shall have the right to impose reasonable and customary rules and regulations based upon the nature of the Project as either a single-tenant or a multi-tenant First Class Life Sciences Project (which rules and regulations shall be modified by Landlord in accordance with Tenant’s reasonable requests, from time to time, taking into account whether or not Tenant and its Permitted Transferees are the sole occupants of all occupied space in the Project) regarding the use of the Project, as reasonably deemed necessary by Landlord with respect to the orderly operation of the Project as either a single-tenant or occupancy multi-tenant First Class Life Sciences Project, including, but not limited to, reasonable rules and regulations for the safe and sanitary operation of any fitness/wellness center or cafeteria operated by Tenant, and for the reasonable mitigation of noise, odors and other effects of such operations on other occupants of the Project, and provided that such rules and regulations are consistent with rules and regulations then being enforced by landlords of Comparable Buildings, with respect to tenants leasing a similar proportion of First Class Life Sciences Projects as Tenant is then leasing pursuant to this Lease, Tenant shall comply with such rules and regulations. Tenant shall not do or permit anything to be done in or about the Premises which will in any way damage the reputation of the Project or obstruct or interfere with the rights of other tenants or occupants of the Buildings, or injure or annoy them or use or allow the Premises to be used for any improper, unlawful or objectionable purpose, nor shall Tenant cause, maintain or permit any nuisance in, on or about the Premises. Tenant shall comply with, and Tenant's rights and obligations under the Lease and Tenant's use of the Premises for any purpose or in any manner which is or may beshall be subject and subordinate to, directly or indirectlyall recorded easements, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or and restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance in or about any of the Premises, nor bring or keep anything therein which, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premises, nor shall Tenant sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premises, or as are not related to or afforded by Tenant’s improvements or actsProject.

Prohibited Uses. (a) Tenant will not use, occupy or permit the use or occupancy of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit any Tenant Related Parties to remain commit any waste upon the Premises or Common Area. Tenant and Tenant Related Parties shall not do or permit anything to be done in the Premises or do or permit anything to be done by any of them in other parts of the Premises. (d) Building, Project or Common Area which will obstruct or interfere with the rights of any other tenants of the Project, other authorized users of the Common Area, or occupants of neighboring property, or injure or unreasonably annoy them. Tenant shall not install conduct or permit any auction or sale open to remain the public to be held or conducted on or about the Premises, Building, Project or Common Area. Neither Tenant nor any improvements to any of Tenant Related Parties shall use or knowingly allow the Premises which exceed to be used for any hazardous purpose, nor shall Tenant or any Tenant Related Parties cause, maintain, or permit any nuisance in, on or about the structural loads of floors or walls of any buildings located on such Premises, Building, Project or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Common Area. Tenant shall not commit overload existing electrical systems or other mechanical equipment servicing the Building, impair the efficient operation of the sprinkler system or the heating, ventilation or air conditioning equipment within or servicing the Building or Premises or damage (ordinary wear and tear excepted), overload or corrode or misuse the sanitary sewer system. Tenant and Tenant Related Parties shall not do or knowingly permit anything to be committed any action or circumstance done in or about any of the Premises, Premises nor bring or keep anything therein whichin the Premises which will in any way increase the rate of any insurance upon any portion of the Project or any of its contents, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premisesany portion of the Project or any of its contents, nor shall Tenant or any Tenant Related Parties keep, use or sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance. In the event the rate of any insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at upon any portion of the Project or any of its contents is increased because of Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with the requirements of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the Tenant Related Party’s particular use or occupancy of all of the Premises, excluding Tenant shall pay, as Additional Rent, the full cost of such increase; provided, however this provision shall in no event be deemed to constitute a waiver of Landlord’s right to declare a default hereunder by reason of the act or conduct of Tenant or any Tenant Related Parties causing such increase or of any other rights or remedies of Landlord in connection therewith. Tenant and Tenant Related Parties shall not place any loads upon the floor, walls or ceiling of the Premises which would endanger the Building or the structural changes as do not relate elements thereof or of the Premises, nor place any harmful liquids in the drainage system of the Building or Common Area. No waste materials or refuse shall be dumped upon or permitted to remain upon any part of the Project except in enclosed trash containers designated for that purpose by Landlord. No materials, supplies, equipment, finished products (or affect the use semi-finished products), raw materials, or occupancy other articles of any nature shall be stored outside of the Premises, or as are be permitted to remain outside of the Premises, except for temporary loading and unloading. Tenant shall not related tint or frost, or permit any Tenant Related Parties or their respective contractors or representatives to tint or afforded by Tenant’s improvements or actsfrost, the windows of the first floor of the Building.

Prohibited Uses. (a) Tenant will not use, occupy or permit the use or occupancy of any of the Premises for any purpose or in any manner which is or may be, directly or indirectly, in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant shall not keep or permit to be kept any substance in, or conduct or permit to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors or conditions, or make undue noise or create undue vibrations. (c) Tenant Tenant's agents shall not commit or permit to remain any waste to any of the Premises. (d) Tenant shall not install or permit to remain any improvements to any of the Premises which exceed the structural loads of floors or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit --------------- suffer to be committed any action waste upon the Premises. Tenant and Tenant's agents shall not do or circumstance permit anything to be done in or about the Premises or Common Area which will in any way obstruct or unreasonably interfere with the rights of any other tenants of the Building, other authorized users of the Common Area, or occupants of neighboring property, or injure them. Tenant shall not conduct or permit any auction or sale open to the public to be held or conducted on or about the Premises or Common Area. Tenant and Tenant's agents shall not use or allow the Premises to be used for any unlawful, immoral or hazardous purpose or any purpose not permitted by this Lease, nor shall Tenant or Tenant's agents cause, maintain, or permit any nuisance in, on or about the Premises, . Tenant and Tenant's agents shall not do or permit anything to be done in or about the Premises nor bring or keep anything therein whichin the Premises which will in any way increase the rate of any insurance upon any portion of the Project or any of its contents, directly or indirectly, would or might cause a cancellation of any insurance policy covering such Premisesany portion of the Project or any of its contents, nor shall Tenant or Tenant's agents keep, use or sell or permit to be kept, used or sold in or about any of the Premises any articles which may be prohibited by a standard form policy of fire insurance unless Tenant provides additional insurance coverage extending protection to cover all risks associated with those articles. (f) Tenant shall, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now in force or which may hereafter be in force and with insurance. In the requirements event the rate of any board insurance upon any portion of fire underwriters the Project or any of its contents is increased because of Tenant's particular use of the Premises or that of Tenant's agents, Tenant shall pay, as Additional Rent, the full cost of such increase; provided, however this provision shall in no event be deemed to constitute a waiver of Landlord's right to declare a default hereunder by reason of the act or conduct of Tenant or Tenant's agents causing such increase or of any other similar body now rights or hereafter constituted relating to remedies of Landlord in connection therewith. Tenant and Tenant's agents shall not place any loads upon the floor, walls or affecting ceiling of the use Premises which would endanger the Building or occupancy of all the structural elements thereof or of the Premises, excluding such structural changes as do not relate to or affect nor place any harmful liquids in the use or occupancy drainage system of the PremisesBuilding or Common Area. No waste materials or refuse shall be dumped upon or permitted to remain upon any part of the Project except in enclosed trash containers designated for that purpose by Landlord. No materials, supplies, equipment, finished products (or semi-finished products), raw materials, or as are not related other articles of any nature shall be stored upon, or be permitted to or afforded by Tenant’s improvements or actsremain on, any portion of the Project outside the Premises.

Prohibited Uses. (a) Tenant will LESSEE shall not use, occupy or permit the use or occupancy of any of the said Premises for any purpose or in any manner use other than that which is or may be, directly or indirectly, specified in violation of any (i) judicial decisions, order, injunctions, writs, statutes, rulings, rules, regulations, promulgations, directives, permits, certificates or ordinances of any governmental authority in any way applicable to Tenant or the Premises, including but not limited to zoning, environmental and utility conservation matters (hereinafter “Legal Requirements”), (ii) covenants, conditions, or restrictions applicable to such Premises and appearing of record in the office of the county recorder of the county in which such Premises are located on or before the date on which such Premises became subject to this Lease, or (iii) insurance requirements. (b) Tenant and shall not keep or permit them to be kept used, for any substance inother purposes, without first obtaining the written consent of LESSOR, which consent shall not be unreasonably withheld. LESSEE shall promptly and continuously comply with all laws, orders, and regulations of the State, County, and City affecting the use, occupation, safety, and cleanliness of the said Premises and the equipment of LESSEE. LESSEE may not display or conduct sell items or permit allow carts, portable signs, devices or any other objects to be conducted any operation from, any of the Premises which is not reasonably consistent with the Permitted Use for such Premises and which might emit offensive odors stored or conditions, or make undue noise or create undue vibrations. (c) Tenant shall not commit or permit to remain any waste to any outside the defined exterior walls and permanent doorways of the Premises. (d) Tenant shall . LESSEE further agrees not to install any exterior lighting, amplifiers or permit to remain any improvements to any of the Premises which exceed the structural loads of floors similar devices or walls of any buildings located on such Premises, or adversely affect the mechanical, plumbing or electrical systems of any such buildings, or affect the structural integrity of any such buildings in any way. (e) Tenant shall not commit or permit to be committed any action or circumstance use in or about any of the Premises, nor any advertising medium which may be heard or seen outside the Premises, such as flashing lights, searchlights, loudspeakers, phonographs, or radio broadcasts. LESSEE shall not do or permit anything to be done in or about the Premises nor bring in or keep anything therein which, directly which will in any way increase the existing rate or indirectly, would affect any fire or might cause other insurance upon the Premises or any building of which the Premises may be a cancellation part or any of any insurance policy covering such Premisesits contents, nor shall Tenant LESSEE sell or permit any articles to be kept, used or sold in or about any of the Premises any articles Premises, which may be prohibited by a standard form policy of fire insurance. If LESSOR'S insurance unless Tenant provides additional insurance coverage extending protection premium is increased as a result of LESSEE'S business operation, LESSEE agrees to cover all risks associated with those articles. (f) Tenant shallpay said increase. In the event the Premises represent a section of a larger building, at Tenant’s sole cost and expense, promptly comply with all Legal Requirements now LESSEE shall not do or permit anything to be done in force or about the Premises which may hereafter be will in force and any way obstruct or interfere with the requirements rights of other tenants or occupants of the building of which the Premises may be a part, or injure or annoy them, or use or allow the Premises to be used for any unlawful or objectionable purpose, nor shall LESSEE cause, maintain or permit any nuisance in, or on, or about the Premises. LESSEE shall not commit or allow to be committed any waste in or upon the Premises. LESSEE shall keep the Premises in a clean and wholesome condition, free of any board of fire underwriters or other similar body now or hereafter constituted relating to or affecting the use or occupancy of all of the Premisesreasonably objectionable noises, excluding such structural changes as do not relate to or affect the use or occupancy of the Premisesodors, or as are not related to or afforded by Tenant’s improvements or actsnuisances beyond its contemplated uses set forth herein.