LifeTec Group Clause Samples

LifeTec Group. LifeTec Group (LTG) has played a substantial role in our Innovation and Sustainability work package, particularly task T4.5 Pre-commercial Activities. The main tasks of LTG in this project are the development and application of cardiovascular in silico models and tools and to combine them with the models of other participants, to create workflows, pipelines and interfaces. LTG is involved in business development for the ▇▇▇ by working on the Innovation Plan, which established mechanisms to actively promote in silico methods to, for example, the cardiovascular devices and pharmaceutical industry. The Innovation Plan is a live document which is maintained throughout the lifetime of our Centre. To date, LTG has developed a tool to provide clinical decision support as a Software as a Service. More specifically, discussions with clinicians have identified a challenge in the decision-making process to treat difficult coronary stenosis either by bypass surgery or by placing a stent. The simulation tool can predict the outcome of both interventions as well as present the accuracy of said prediction, which would be very helpful in the decision-making process and would reduce the cost of treating complications. The idea is that relatively (computationally) cheap 1D models with input from patient specific data will provide quick results of both interventional strategies, and that running many cases in parallel allows for a population of results that not only provides a result but also an assessment of the expected accuracy of the result. In the development of the tool, sensitivity analyses are performed in SURFsara facilities, and containers are in development that will facilitate the running of simulations without having to support local software installations in the SURFsara computing centres. Currently, the tool is being used as a local software in clinical practise on clinical data to obtain feedback on the accuracy of the predicted outcome. The 1D models can also be used as a tool to provide inlet or outlet boundary conditions for more complex 3D cardiovascular models, such as to incorporate such 3D local simulations into a larger vascular computational environment. Coupling between 0D and 1D simulations and 3D CFD simulations have been achieved with ANSYS software, as well as FlowVision: CFD software developed in the collaboration of Capvidia (Belgium) and TESIS (Russia). The verification of 0D/1D model results with 3D CFD simulations will be performed on SURFs...