Common use of Evaluation Activities Clause in Contracts

Evaluation Activities. To assess the viability of SCH 58500 Ad-p53 (Reference: U.S. IND #6754), MULTIVIR shall perform the following: Expression of SCH 58500 Ad-53: • Use Technology to express SCH 5800 Ad-53 for use in the Assays specified below • Procedural Ref for determination of viral particle concentration: ▇.▇. ▇▇▇▇▇▇▇ et al, HUMAN GENE THERAPY 8:453-465 (March 1, 1997) Assays: • Adenoviral vector titer (IU/ml) • Adenoviral vector particle number (vp) concentration • p53 protein expression: dose-response. Includes adenovirus stability testing • Inhibition of cell proliferation: dose-response