Common use of DOW Clause in Contracts

DOW. HDCI shall inform Dow Pharmaceutical Sciences ("Dow") that HDCI grants its permission for Interneuron to continue the stability studies and protocols that are being conducted at Dow. HDCI shall pay any remaining amounts due to Dow to the extent incurred prior to the Effective Date (including without limitation, the fee of approximately $[* ] for the stability study pull authorized on April 19, 2000) and Interneuron shall be responsible for the payment of any fees for any stability study pulls performed after the Effective Date of this Agreement. HDCI shall use its best efforts to obtain the data generated by Dow and shall provide such data to Interneuron when it is received. ---------------------- * Confidential treatment requested.

DOW. HDCI shall inform Dow Pharmaceutical Sciences ("Dow") that HDCI grants --- its permission for Interneuron to continue the stability studies and protocols that are being conducted at Dow. HDCI shall pay any remaining amounts due to Dow to the extent incurred prior to the Effective Date (including without limitation, the fee of approximately $[* *] for the stability study pull authorized on April 19, 2000) and Interneuron shall be responsible for the payment of any fees for any stability study pulls performed after the Effective Date of this Agreement. HDCI shall use its best efforts to obtain the data generated by Dow and shall provide such data to Interneuron when it is received. ---------------------- ----------------------------------- * Confidential treatment requested.. APPENDIX 4.2 ------------ FORM OF PRESS RELEASE APPENDIX 5.2(A) --------------- Phase 2 Study Guidelines ------------------------