Common use of 3Duties Clause in Contracts

3Duties. Executive will continue to render such business and professional services in the performance of Executive’s duties (consistent with Executive’s position as Chief Medical Officer to the Company, and for the benefit of the Company’s parent, Bicycle Therapeutics plc (“BTL”)). Executive shall report to BTL’s Chief Executive Officer. For the avoidance of doubt and for ease of understanding the intent of the arrangement, all of Executive’s services described herein shall be provided directly to the Company, which will, in turn, continue to provide such services to BTL pursuant to an arm’s length intra- company agreement. To the extent that Executive engages in any services contemplated herein on BTL’s behalf that involve the execution and negotiation of legal documents, such services will be performed in the United Kingdom. Executive shall continue to be expected to perform Executive’s duties under this Agreement remotely from Executive’s home in , but ​ ​ including regular travel to the Company’s office in Cambridge, Massachusetts, or such other location as assigned, reimbursed subject to the Company’s corporate travel policy. In addition, Executive shall make such business trips to such places as may be reasonably necessary or advisable for the efficient operations of the Company.

3Duties. Executive will continue to render such business and professional services in the performance of Executive’s duties (consistent with Executive’s position as Chief Medical Financial Officer to the Company, and for the benefit of the Company’s parent, Bicycle Therapeutics plc (“BTL”)). Executive shall report to BTL’s Chief Executive Officer. For the avoidance of doubt and for ease of understanding the intent of the arrangement, all of Executive’s services described herein shall be provided directly to the Company, which will, in turn, continue to provide such services to BTL pursuant to an arm’s length intra- intra-company agreement. To the extent that Executive engages in any services contemplated herein on BTL’s behalf that involve the execution and negotiation of legal documents, such services will be performed in the United Kingdom. Executive shall continue to be expected to perform Executive’s duties under this Agreement remotely from Executive’s home in New York City, New York, but ​ ​ including regular travel to the Company’s office in Cambridge, Massachusetts, or such other location as assigned, reimbursed subject to the Company’s corporate travel policy. In addition, Executive shall make such business trips to such places as may be reasonably necessary or advisable for the efficient operations of the Company.