Single Units Analysis Clausole campione
Single Units Analysis. In the CHR condition we found 57 out of 98 (58%) neurons (31/60 - 52% - in Mk1 and 26/38 - 68% - in Mk2) with a significant modulation of their discharge during at least one behaviour, whereas the remaining fraction did not appear to be responsive for any of the scored behaviours (Figure 12A). In the NER condition the number of neurons modulated for at least one behaviour dropped down to 34 out of 98 (35%), in particular 17/60 (28%) in Mk1 and 17/38 (45%) in Mk2 (Figure 12B). this neuron tends to generally maintain the same functional properties, showing modulation both for active and passive mouth movements in spite of a more noisy baseline and less clearly tuned responses. Lastly, Figure 16 shows an example of a neuron from Mk2 which is modulated by all the grasping action performed with the controlateral hand (toward food or no food items) in the CHR condition; it also shows a modulation for grasping actions in the NER condition but, in this case, it is modulated by grasping actions performed to climb up or down the wooden structure regardless of the hand used and it shows no modulation for grasping actions towards fruit pieces. It is clear, based on the example neurons, that the correspondence in terms of response properties between the neural responses in CHR and NER can be very broad or absent at all. In Figure 17 we graphically reported the number of neurons showing an increase in their firing rate for each behaviour tested in the two conditions. For every grasping behaviour considered in the analysis, the number of neurons modulated in the CHR condition was markedly higher than the number of neurons modulated in the NER condition. Notably in the CHR condition the number of neurons modulated by grasping actions performed with the controlateral hand was higher than those modulated by grasping actions with the ipsilateral hand (this is particularly true for Mk2) but this difference disappears in the NER condition. A high number of neurons was also modulated by mouth behaviours (either passive or active) in the CHR conditions whereas in the NER condition this number dropped down for active mouth behaviours but slightly increased for passive behaviours, in particular when monkey was receiving fruit juice through a syringe. Passive delivery of “Solid reward” was not tested for Mk1 in the NER condition, making impossible to compare the coding of this behaviour between the two contexts. Interestingly, most of the neurons modulated by mouth behaviour have b...
