Unproven definition

Unproven means that there is not substantial evidence that a treatment is effective for the condition. This may reflect the absence of any data or the absence of studies of acceptable quality. It includes: Treatment that is considered “standard of care” but which has never been subject to rigorous scientific testing or submitted to FDA for approval. Treatment for which there are no, or insufficient, clinical or pre-clinical data to support safety or efficacy. A product that is not approved for, nor does the labeling for the product contain, the specific indication or patient population under study. “Unsatisfactory” means that the available product or therapy is effective, but there are drawbacks to its use, such as: Safety issues (e.g., high incidence of adverse effects). Efficacy issues, including: The time for the treatment to be effective is too long. The treatment has limitations related to the setting in which it is needed (e.g., should be administered in the field but needs refrigeration; is not portable).
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Unproven means that there is no substantial evidence that a treatment is effective for the condition of interest. This may reflect the absence of any data or the absence of studies of acceptable quality. The term “unproven therapy” includes:
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Examples of Unproven in a sentence

  • Procedures that are considered to be Experimental or Investigational or Unproven Services.

  • The fact that an Experimental or Investigational or Unproven Service, treatment, device or pharmacological regimen is the only available treatment for a particular condition will not result in Benefits if the procedure is considered to be Experimental or Investigational or Unproven in the treatment of that particular condition.

  • Unproven treatments are treatments, procedures or supplies that lack significant medical documentation to support their effectiveness.

  • The fact that an Experimental, or Investigational or Unproven Service, treatment, device or pharmacological regimen is the only available treatment for a particular condition will not result in benefits if the procedure is considered to be Experimental or Investigational or Unproven Service in the treatment of that particular condition.

  • Experimental or Investigational Services and Unproven Services and all services related to Experimental or Investigational and Unproven Services are excluded.

  • Procedures that are considered to be Experimental, Investigational or Unproven.

  • Experimental or Investigational Services or Unproven Services and medications; medications used for experimental indications and/or dosage regimens determined by the Company to be experimental, investigational or unproven.

  • Experimental or Investigational and Unproven Services and all services related to Experimental or Investigational and Unproven Services are excluded.

  • Experimental or Investigational Services or Unproven Services and medications; medications used for experimental indications for certain diseases and/or dosage regimens determined by the Company to be experimental, investigational or unproven.

  • The fact that an Experimental, or Investigational or Unproven Service, treatment, device or pharmacological regimen is the only available treatment for a particular condition will not result in benefits if the procedure is considered to be Experimental or Investigational or Unproven in the treatment of that particular condition.

Related to Unproven

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  • Program area means a general group of disciplines in which one or more degree programs,

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  • offensive weapon means an article made or adapted for use for the purpose of causing injury to or incapacitating a person or which any person having it with him or her intends to use for that purpose;

  • mining area means all those pieces of land containing two hundred and forty‑six (246) square miles or thereabouts situate in what is known to the parties as the “Xxx Xxxxx‑Siberia Nickel Laterite Area” the subject of the mineral claims applications for mineral claims and Temporary Reserves listed in the First Schedule hereto which are generally delineated and respectively coloured green and orange and red in the plan marked “X” signed by or on behalf of the parties for the purpose of identification;

  • drilling means the act of boring a hole to reach a proposed bottom hole location through which oil or gas may be produced if encountered in paying quantities, and includes redrilling, sidetracking, deepening, or other means necessary to reach the proposed bottom hole location, testing, logging, plugging, and other operations necessary and incidental to the actual boring of the hole;

  • mining areas means the areas delineated and coloured red on the Plan marked “A” initialled by or on behalf of the parties hereto for the purposes of identification;

  • Reservoir means a porous and permeable underground formation containing a natural accumulation of producible oil or gas that is confined by impermeable rock or water barriers and is individual and separate from other reservoirs.

  • Mine means to carry on an operation with a view to, or for the purpose of—

  • Terminal means a device authorized by a Party Lottery to function in an on-line, interactive mode with the lottery's computer gaming system for the purpose of issuing lottery tickets and entering, receiving, and processing lottery transactions, including purchases, validating tickets, and transmitting reports.

  • ore means any rock soil or alluvium bearing diamonds mined from mining leases granted pursuant to this Agreement;

  • Substances means chemical elements and their compounds in the natural state or obtained by any production process, including any additive necessary to preserve the stability of the products and any impurity deriving from the process used, but excluding any solvent which may be separated without affecting the stability of the substance or changing its composition;

  • Landing area means that part of a movement area intended for the landing or take-off of aircraft;

  • Infiltration means water other than wastewater that enters a sewer system (including sewer system and foundation drains) from the ground through such means as defective pipes, pipe joints, connections, or manholes. Infiltration does not include, and is distinguished from, inflow.

  • Abused means subjected to child abuse.

  • Salvaging means the lawful and controlled removal of reusable materials from solid waste.

  • Depth , in respect of a building, means the measured distance between the front line of the building and the back line of the rear main wall which separates the main building from the open space;

  • Alcohol means the intoxicating agent in beverage alcohol, ethyl alcohol, or other low molecular weight alcohols including methyl and isopropyl alcohol.

  • Mineral Products means the commercial end products derived from operating the Property as a mine:

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  • Production Area means that part of the animal feeding operation that includes the animal confinement area, the manure storage area, the raw materials storage area, and the waste containment areas. The animal confinement area includes, but is not limited to, open lots, housed lots, feedlots, confinement houses, stall barns, free stall barns, milkrooms, milking centers, egg washing or egg processing areas, areas used for the storage and disposal/treatment of mortalities, cowyards, barnyards, medication pens, walkers, animal walkways, and stables. The manure storage area includes, but is not limited to, lagoons, runoff ponds, storage sheds, stockpiles, under-house or pit storages, liquid impoundments, static piles, and composting piles. The raw materials storage area includes, but is not limited to, feed silos, and silage bunkers. The waste containment area includes, but is not limited to, settling basins and areas within berms and diversions which separate uncontaminated stormwater.

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