Examples of TKI in a sentence
AZD9291, an irreversible EGFR TKI, overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer.
We are grateful for financial support from the Dutch Ministry of Economic Affairs, via the Top Sector Alliance for Knowledge and Innovation (TKI) program IBChampion.
S4† for the UV-vis spectra.AcknowledgementsThis project is co-financed by TKI-Energie from Toeslag voor Topconsortia voor Kennis en Innovatie (TKI) from the Ministry of Economic Affairs and Climate Policy, the Netherlands.
Refinery Company shall receive, at no cost to either Owner, all return utility streams consisting primarily of low pressure steam (but excluding sulfur from the Offsite Sulfur Recovery Unit) and steam condensate under the TKI Phase II Agreement.
Fertilizer Company shall not amend or terminate the TKI Phase II Agreement without the prior written consent of Refinery Company, which consent shall not be unreasonably withheld or delayed.
The TKI General Plant and Labor Costs shall be shared equally by the Parties; provided, however, that in those instances where a particular cost can be reasonably determined to be associated with a particular Party, such Party shall bear such cost.
Refinery Company shall provide to TKI the utilities described in Section 2.6 of the TKI Phase II Agreement.
This objective was assessed by comparing the efficacy, PFS to RECIST v1.1 by investigator assessment, of single-agent TAGRISSO compared with SoC EGFR TKI therapy in the tissue-positive, Guardant360 CDx-positive patients enrolled in FLAURA.The possible influence of tissue-negative Guardant360 CDx-positive patients in the effectiveness of the Guardant360 CDx was assessed through a sensitivity analysis.
In each timeframe, there was no meaningful difference in mean time to best response between TKI cohorts.
Depending on the regions where they are located (Figure 1), mutations can actually interrupt critical contact points between the TKI and BCR-ABL1 protein, or they can induce a conformational change, resulting in a protein to which TKI is unable to bind.