Significant Improvements definition

Significant Improvements means any improvements which either (a) comprise such significantly new scope that new clinical trial(s) (i.e., more than a single equivalency trial) would be required, or (b) whose incorporation in the license rights granted herein would require the payment of new fees or royalties to third parties. Significant Improvements does not include minor improvements, such as formulation, affinity, vector function, or shelf half-life, for which no new clinical trial (other than a single Product equivalency trial) is required.
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Examples of Significant Improvements in a sentence

  • Actual Q2 2013 throughput used as an approximation for gathering capacity Significant Improvements to Regency & PVR Business Profile 2013E Gross Margin Regency1 PVR Pro Forma NGL Services NGL Services 12% Coal 8% 2 7% Coal 24% Nat.

  • The Redesigned Workhorse C-Series Up Close Working Alongside UPS, We Have Made Significant Improvements to the C1000 Gen 1 (E-Series) C1000 Total Vehicle 11,000 lbs <7,000 lbs Weight MPGe 32 40 % Maintenance Costs Reduced >50% >60% Floor Height 32” 14-24” Distance <100 miles >100 miles Range Charging Time >6 hours from empty <6 hours from empty Battery Pack 80-120 kWh 71 kWh Capacity Work Ahead.

  • Longer term capital needs are likely to be covered with operating cash flow and traditional project financing as the Company and the green hydrogen industry grow exponentially into the second half of the decade.Plug Publishes 2022 ESG Report with Significant Improvements in Key DisclosuresFor its 2022 ESG Report, Plug developed a GHG Inventory in line with GHG Protocol and set a baseline for 2022 scope 1 and 2 emissions.

  • Pastore For news media (202) 546-6451 FOR IMMEDIATE RELEASECRIIMI MAE REPORTS FOURTH QUARTER NET INCOME AND YEAR 2003 RESULTSResults Include Significant Improvements in Net Interest MarginRockville, MD, March 9, 2004 - - CRIIMI MAE Inc.

  • Hudson Global Reports 2014 First Quarter Results Significant Improvements in Gross Margin and Adjusted EBITDADemonstrates Traction of Ongoing TransformationAccelerating Strategic Actions to Focus on Core Business and Improve EfficiencyNEW YORK, NY - May 1, 2014 - Hudson Global, Inc.

  • Borrower Parties may make alterations and/or improvements to the Properties which are not Significant Improvements without the prior consent of Agent.

  • This system uses a Burr Brown OPA627 operational amplifier with a feedback resister of 10 Mohm.

Related to Significant Improvements

  • Project Improvements means site improvements and facilities that are:

  • Tenant Improvements Defined in Exhibit B, if any.

  • Tenant Improvement Work means the construction of the Tenant Improvements, together with any related work (including demolition) that is necessary to construct the Tenant Improvements.

  • Minimum Improvements means devoting the Development Property to its intended Use and construction of approximately a square foot parking facility for use as parking for the Developer as identified and set forth in Exhibit C and constructed in accordance with the Construction Plans submitted to and approved by the Authority. After completion of the Minimum Improvements, the term shall mean the Development Property as improved by the Minimum Improvements.

  • Joint Improvements means Improvements the inventors of which are jointly (a) employees of, or others obligated to assign inventions to, ImmunoGen or any Affiliate of ImmunoGen, and (b) employees of, or others obligated to assign inventions to, Lilly or any Affiliate of Lilly.

  • Needs Improvement the Educator’s performance on a standard or overall is below the requirements of a standard or overall, but is not considered to be unsatisfactory at this time. Improvement is necessary and expected.  Unsatisfactory: the Educator’s performance on a standard or overall has not significantly improved following a rating of needs improvement, or the Educator’s performance is consistently below the requirements of a standard or overall and is considered inadequate, or both.

  • Site Improvements means any construction work on, or improvement to, streets, roads, parking facilities, sidewalks, drainage structures and utilities.

  • Private Improvements means the improvements to be constructed on the Property that are not Public Improvements.

  • Leasehold Improvements means all leasehold improvements situated in or on the Leased Real Property and owned by Seller.

  • Infrastructure Improvements means a street, road, sidewalk, parking facility, pedestrian mall, alley, bridge, sewer, sewage treatment plant, property designed to reduce, eliminate, or prevent the spread of identified soil or groundwater contamination, drainage system, waterway, waterline, water storage facility, rail line, utility line or pipeline, transit-oriented development, transit-oriented property, or other similar or related structure or improvement, together with necessary easements for the structure or improvement, owned or used by a public agency or functionally connected to similar or supporting property owned or used by a public agency, or designed and dedicated to use by, for the benefit of, or for the protection of the health, welfare, or safety of the public generally, whether or not used by a single business entity, provided that any road, street, or bridge shall be continuously open to public access and that other property shall be located in public easements or rights-of-way and sized to accommodate reasonably foreseeable development of eligible property in adjoining areas. Infrastructure improvements also include 1 or more of the following whether publicly or privately owned or operated or located on public or private property:

  • Substantial improvement means any combination of repairs, reconstruction, rehabilitation, addition, or other improvement of a structure, taking place during any one-year period for which the cost equals or exceeds 50 percent of the market value of the structure before the “start of construction” of the improvement. This term includes structures which have incurred “substantial damage”, regardless of the actual repair work performed. The term does not, however, include either:

  • Improvements shall have the meaning set forth in the granting clause of the Mortgage.

  • Project Work has the meaning ascribed thereto in Section 2.03.

  • Building Work has the meaning given to it in section 6 of the Building and Construction Industry (Improving Productivity) Act 2016 (Cth);

  • Demolition works means any physical activity to tear down or break up a structure (or part thereof) or surface, or the like, and includes the loading of demolition waste and the unloading of plant or machinery.

  • Capital Improvements mean the purchase, renovation, rehabilitation, or construction of permanent land, buildings, structures, equipment and furnishings used directly for or in the Project, and any goods or services for the Project that are purchased and capitalized under GAAP, including any organizational costs and research and development costs incurred in Illinois. Capitalized lease costs for land, buildings, structures or equipment shall be included in “Capital Improvements” only if the lease term, including any extensions or options to extend, equals or exceeds the term of this Agreement, and provided that such lease costs are valued at their present value using the corporate interest rate prevailing at the time the Company filed its Application with the Department.

  • Construction Works means all works and things necessary to complete the Project in accordance with this Agreement;

  • demolition work means a method to dismantle, wreck, break, pull down or knock down of a structure or part thereof by way of manual labour, machinery, or the use of explosives;

  • Project means the goods or Services described in the Signature Document or a Work Order of this Contract.

  • Public Improvements means only the following improvements: housing facilities; garbage disposal plants; rubbish disposal plants; incinerators; transportation systems, including plants, works, instrumentalities, and properties used or useful in connection with those systems; sewage disposal systems, including sanitary sewers, combined sanitary and storm sewers, plants, works, instrumentalities, and properties used or useful in connection with the collection, treatment, or disposal of sewage or industrial wastes; storm water systems, including storm sewers, plants, works, instrumentalities, and properties used or useful in connection with the collection, treatment, or disposal of storm water; water supply systems, including plants, works, instrumentalities, and properties used or useful in connection with obtaining a water supply, the treatment of water, or the distribution of water; utility systems for supplying light, heat, or power, including plants, works, instrumentalities, and properties used or useful in connection with those systems; approved cable television systems, approved cable communication systems, or telephone systems, including plants, works,

  • Licensee Improvements means any improvement, enhancement, modification, derivative work or upgrade to any of Licensor Patent Rights made, conceived, reduced to practice, affixed or otherwise developed by or on behalf of Licensee during the term of this Agreement and solely as exercised under the License.

  • Tenant’s Work means all improvements, alterations, fixture, equipment, and signage installation, and furniture placement necessary or appropriate for the conduct of the Permitted Use, including all work described as Tenant’s Work on Exhibit D, attached (the “Work Letter”).