SGLT‑2 Class definition
SGLT‑2 Class. ‑ means the class of compounds that has as a primary mechanism of action (i.e., having an IC50 less than 100 nanomolar), the inhibition of SGLT‑2. For clarity, in the case of prodrugs used for the delivery of compounds in the SGLT‑2 Class, the foregoing definition pertains to the bioactive agent that would be released from the prodrug upon administration to patients. Also for clarity, the foregoing definition shall exclude any delivery vehicle, such as O‑glucosides, that is utilized solely for drug delivery purposes in respect of a biologically active agent.