PINP definition

PINP means Phillip Island Nature Parks
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Examples of PINP in a sentence

  • The following markers of bone formation will be measured: · Serum N-terminal propeptide of type I procollagen (PINP); · Serum bone-specific alkaline phosphatase (BSAP); · Serum osteocalcin.

  • Bone formation (PINP, osteocalcin, BSAP) and resorption (CTX) markers will also be assessed.

  • Other efficacy endpoints will include change in wrist BMD in BA058-treated patients, and changes in serum PINP, bone-specific alkaline phosphatase, osteocalcin, and CTX across treatment.

  • Additional secondary endpoints will include change in standing height and changes in serum bone markers across treatment, such as PINP, osteocalcin, and bone-specific alkaline phosphatase.

  • The bone formation markers N-terminal propeptide of type 1 procollagen (PINP), C-terminal propeptide of type 1 procollagen (PICP), bone specific alkaline phosphatase (BSAP) and serum osteocalcin) will be assessed by analysis of blood samples.

  • Increases in the principal markers of bone formation: N-terminal propeptide of type I procollagen (PINP), osteocalcin, and bone-specific alkaline phosphatase (BSAP) are accepted predictors of BMD change (21,22).

  • Changes in serum markers of bone metabolism (PINP, bone-specific alkaline phosphatase, osteocalcin, and CTX) will be analyzed using repeated measures Analysis of Variance (ANOVA) with factors for treatment (treatment groups), time (study period) and their interaction.

  • Clinical and radiographic assessments for fractures will be performed at Month 6 and Month 24, and bone marker assessments of anabolism (PINP, bone-specific alkaline phosphatase and osteocalcin) and resorption (CTX) will be performed at Day 1 and Months 6, 12, 18 and 24.

  • Clinical and radiographic assessments for fractures will be performed at Month 6 and Month 24, and bone marker assessments of anabolism (PINP, bone-specific alkaline phosphatase and osteocalcin) and resorption (CTX) will be performed at Day 1 and Month 6.

  • PINP, CTX, sclerostin and Dkk1 were analysed by the commercial bone marker laboratory at the University of Sheffield.