Metabolome definition
Metabolome means enzymes, receptors, transporters that are direct exponents of cellular, or biochemical reactions (including redox reactions), in each case, that [**], e.g., amino acids, nucleotides, lipids, carbohydrate monomers and dimers. For the avoidance of doubt, “Metabolome” will exclude, for example, proteins that have activity in signal transduction, epigenetic, protein translation, cellular or sub-cellular structures, gene expression, protein degradation via the ubiquitination pathway as their role in cellular function.
Examples of Metabolome in a sentence
Metabolome profile across pregnancy The intervention also led to a healthier metabolic profile across pregnancy from baseline to 34+0 to 36+6 weeks gestation, for the control arm all very low-density lipoprotein (VLDL) particles increased by 1.5–3 SD and intermediate density lipoprotein and specific (large, medium and small) LDL particles increased by 1–2 SD, between the two timepoints.
Metabolome signatures promise to identify amino acid or fatty acid profiles associated with colorectal cancer or high risk (111) have been preliminarily developed in EDRN supported research.