Matrix effect definition

Matrix effect means any change in the method detection limit or practical quantitation limit for a given analyte as a result of the presence of other constituents - either of natural origin or introduced by humans as a result of a release or spill - that are present in the sample of water or soil-pore gas being analyzed.
Matrix effect means an influence of one or more components from the sample matrix on the measurement of the analyte concentration or mass. Matrix effects may be observed as increased or decreased detec- tor responses, compared with those produced by simple solvent solu- tions of the analyte.
Matrix effect means the difference in analytical response between a standard dissolved in the solvent and a matrix- matched standard either without a correction using an internal standard or with correction using an internal standard;

Examples of Matrix effect in a sentence

  • Matrix effect is a prevalent issue encountered in mass spectrometry measurements.

  • Matrix effect was the ratio of ISTD peak areas acquired from brain lysate samples with IS solutions spiked-after extraction and academic IS standard samples.

  • Matrix effect on these tests is also assessed by spiking/linearity checking.


More Definitions of Matrix effect

Matrix effect means any increase in the Method Detection Limit or Peak Quantitation Limit for a given constituent as a result of the presence of other constituents, either of natural origin or introduced through a release, that are present in the sample of water or soil-pore gas being

Related to Matrix effect

  • Stochastic effect means a health effect that occurs randomly and for which the probability of the effect occurring, rather than its severity, is assumed to be a linear function of dose without threshold. Hereditary effects and cancer incidence are examples of stochastic effects. For purposes of these regulations, "probabilistic effect" is an equivalent term.

  • Nonstochastic effect means a health effect, the severity of which varies with the dose and for which a threshold is believed to exist. Radiation-induced cataract formation is an example of a nonstochastic effect. For purposes of these regulations, "deterministic effect" is an equivalent term.

  • Plan Effective Date means the occurrence of the effective date of the Plan according to its terms.

  • Required Effective Date means the relevant Initial Required Effective Date or Increased Required Effective Date (as those terms are defined below).

  • PAL effective date generally means the date of issuance of the PAL permit. However, the PAL effective date for an increased PAL is the date any emissions unit that is part of the PAL major modification becomes operational and begins to emit the PAL pollutant.