LOH definition
Examples of LOH in a sentence
For those elements that cannot be ordered electronically at present per the LOH, the listed SOMEC rate in this category reflects the charge that would be billed to a CLEC once electronic ordering capabilities come on-line for that element.
Please refer to BellSouth's Local Ordering Handbook (LOH) to determine if a product can be ordered electronically.
We have shown that the MassEXTEND (LOH) assay is a reliable and cost-effective method for typing SNPs and detecting LOH of SNP loci using formalin-fixed paraffin- embedded (FFPE) tissue.
Recently, MALDI TOF genotyping of PTPRJ is also published including limited LOH analysis, al- though no validation for LOH was done, and the spectra were not automatically analyzed.6 For FFPE material, the MassEXTEND (LOH) assay is significantly less labor in- tensive than direct sequencing analysis (the main alter- native for detecting LOH at specific SNP loci in tumors).
When selected markers need to be tested in FFPE, the MassEXTEND (LOH) assay may ap- pear to be an excellent option.
Landlord acknowledges that, in accordance with Section 12 of the Partnership Agreement, URH shall be responsible for monitoring, managing and implementing the design, development, construction, furnishing and equipping of the Project on behalf of Tenant, subject to the rights of consent and participation of LOH set forth in such Section 12 of the Partnership Agreement.
Furthermore, in our setting, the MassEXTEND LOH assay is ninefold less expensive, and the throughput is 10 times higher than conventional sequencing.
LOH Analysis of the c.827A>C SNP in PTPRJ with a MassEXTEND LOH Assay and Its Validation In a control experiment (see Materials and Methods), among 48 independent measurements, the c.827A allele was observed with a frequency of 0.766 ± 0.02 and 0.234 ± 0.02 for the c.827C allele (0.02 is the SD).
However, sequence analysis and conventional LOH analysis of the 22 adeno- mas (including MassEXTEND LOH of the adenoma with malignant transformation; Table 2) did not identify LOH of flanking microsatellite markers nor of the c.827 PTPRJ alleles (data of the 21 additional adenomas not shown).
In those tumors (E and F) with ambiguous MassEXTEND LOH, limited allelic im- balances with conventional markers was seen in en- riched tumor cell populations.