Lipid Nanoparticle definition

Lipid Nanoparticle means any delivery technology for mRNA or other nucleic acids using solid particles at room temperature, of 50-1,000 nm size, consisting of solid lipids or a mixture of a solid lipid and a liquid lipid.
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Lipid Nanoparticle has the meaning set forth in the License Agreement.
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Examples of Lipid Nanoparticle in a sentence

  • These lipids would form a nanoparticle, called a Lipid Nanoparticle or LNP.

  • Lipid Nanoparticle Technology for Clinical Translation of siRNA Therapeutics.

  • Lipid Nanoparticle Delivery of siRNA to Osteocytes Leads to Effective Silencing of SOST and Inhibition of Sclerostin In Vivo.

  • Phase 1 Assessment of the Safety and Immunogenicity of an mRNA- Lipid Nanoparticle Vaccine Candidate Against SARS-CoV-2 in Human Volunteers.

  • Whitehead, Lipid Nanoparticle Formulations for Enhanced Co-delivery of siRNA and mRNA.

  • Xxx x No MacMillan, Sobanski, and Xxxx LLC PCT/US2013/042458 May 23, 2013 [2012-284] [2013-246] Lipid Nanoparticle Compositions and Methods of Making and Methods of Using the Same X.

  • In the decade before COVID-19 emerged, Acuitas worked to solve that delivery- system problem: it painstakingly engineered a microscopic sphere of fats called a Lipid Nanoparticle, or “LNP,” that can envelop and protect the mRNA.

  • Chaudhury, Recent Advances in Lipid Nanoparticle Formulations with Solid Matrix for Oral Drug Delivery.

  • If this [Contract] is terminated by the [Bank] pursuant to [Section 25.1], except for [Section 25.1 (viii)], the [Contractor] shall be liable to and indemnify the [Bank] for all losses suffered by the [Bank] as the consequence of termination of the [Contract] in accordance with the terms and conditions set out in [Section 28] below.

  • Lipid Nanoparticle 553 Technology for Clinical Translation of siRNA Therapeutics.

Related to Lipid Nanoparticle

  • Biomarker means a parameter or characteristic in a patient or Patient Sample, the measurement of which is useful (a) for purposes of selecting appropriate therapies or patient populations or monitoring disease susceptibility, severity or state, or monitoring therapies for such patient and/or (b) for predicting the outcome of a particular treatment of such patient.

  • Corrosion inhibitor means a substance capable of reducing the corrosivity of water toward metal plumbing materials, especially lead and copper, by forming a protective film on the interior surface of those materials.

  • Reagent means any product other than fuel that is stored on-board the vehicle and is provided to the exhaust after-treatment system upon request of the emission control system.

  • Cannabinoid means any of the chemical compounds that are the active constituents of marijuana.

  • Cannabinoid edible means food or potable liquid into which a cannabinoid concentrate, cannabinoid extract or dried marijuana leaves or flowers have been incorporated.

  • Opioid antidote means any drug, regardless of dosage amount or method of administration, which has been approved by the United States Food and Drug Administration (FDA) for the treatment of an opioid overdose. “Opioid antidote” includes, but is not limited to, naloxone hydrochloride, in any dosage amount, which is administered through nasal spray or any other FDA-approved means or methods.

  • Antibody means a molecule or a gene encoding such a molecule comprising or containing one or more immunoglobulin variable domains or parts of such domains or any existing or future fragments, variants, modifications or derivatives thereof.

  • Fluoroscopic imaging assembly means a subsystem in which X-ray photons produce a visual image. It includes the image receptor(s) such as the image intensifier and spot-film device, electrical interlocks, if any, and structural material providing linkage between the image receptor and diagnostic source assembly.

  • Prosthesis means an artificial substitute for a missing body part.

  • Opioid antagonist means a drug that binds to opioid

  • Pyrolysis means the thermal degradation of a substance in the absence of any oxidising agent, which does not form part of the substance itself, to produce char and gas and/or liquid; and

  • Vaccine means a specially prepared antigen which, upon administration to a person, will result in immunity and, specifically for the purposes of this rule, shall mean influenza and pneumococcal vaccines.

  • Bioassay means the determination of kinds, quantities or concentrations and, in some cases, the locations of radioactive material in the human body, whether by direct measurement, in vivo counting, or by analysis and evaluation of materials excreted or removed from the human body. For purposes of these rules, “radiobioassay” is an equivalent term.

  • Aerosol coating product means a pressurized coating product containing pigments or resins that dispenses product ingredients by means of a propellant, and is packaged in a disposable can for hand-held application, or for use in specialized equipment for ground traffic/marking applications.

  • Diagnostic mammography means a method of screening that

  • Prosthetic device means a replacement, corrective, or supportive device, other than contact lenses and dental prosthesis, dispensed pursuant to a prescription, including repair or replacement parts for that device, worn on or in the body to do 1 or more of the following:

  • Tetrahydrocannabinol means the natural or synthetic equivalents of the substances contained in the plant, or in the resinous extractives of, Cannabis sativa, or any synthetic substances, compounds, salts, or derivatives of the plant or chemicals and their isomers with similar chemical structure and pharmacological activity.

  • Total tetrahydrocannabinol means the sum of the percentage by weight of tetrahydrocannabinolic acid multiplied by eight hundred seventy-seven thousandths plus the percentage of weight of tetrahydrocannabinol.

  • Cannabinoid extract means a substance obtained by separating cannabinoids from marijuana by:

  • HIV means human immunodeficiency virus.

  • Orthotic device means a custom-fitted or custom-fabricated medical device that is applied to a part of the human body to correct a deformity, improve function, or relieve symptoms of a disease.

  • Marihuana-infused product means a topical formulation, tincture, beverage, edible substance, or similar product containing marihuana and other ingredients and that is intended for human consumption.

  • Nicotine product means a product that contains nicotine and is not any of the following:

  • Biodegradable means degradable through a process by which fungi or bacteria secrete enzymes to convert a complex molecular structure to simple gasses and organic compounds.

  • Assay means a laboratory analysis of Crude Petroleum to include the following: A.P.I. Gravity, Reid vapor pressure, composition, pour point, water and sediment content, sulfur content, viscosity, distillation, hydrogen sulfide, flash/boiling point and other characteristics as may be required by Carrier.

  • Biological Samples means any physical samples obtained from Study Participants in accordance with the Protocol for the purposes of the Study.