Lead Structures definition

Lead Structures means Compounds identified in the Target Screening Phase of the Metabolic Program that meet pre-defined criteria set forth in the Research Plan, and the expansion series developed within a Strategic Project.
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Examples of Lead Structures in a sentence

  • License referenced in Section 4.2 below with respect to any or all Validated Lead Structures for the given Target (the "OVLS DECLARATION").

  • The initial stage of this process shall be the development of assays and the screening of compounds to determine which compounds should be selected as Lead Structures.

  • Identified Lead Structures will be further investigated, including performing Analoging Programs on such Lead Structures, and performing needed pharmacology, drug optimization, further chemistry investigation, and toxicology and pharmacokinetic investigations, as appropriate.

  • With respect to each Target and on a Target by Target basis, the VLS Evaluation Term shall commence on the date Phytera delivers to Chiron all Validated Lead Structures and all related information for the Target pursuant to section 4.1 and shall conclude ninety (90) days after such date, unless otherwise mutually agreed.

  • CuraGen shall provide additional GeneCalling expression profiling, characterize the pharmacogenomic properties of the Lead Structures in appropriate cellular, non-mammalian or animal disease models, and provide additional pharmacogenomic validation for the Qualified Target in appropriate human cellular models at each Metabolic Program Strategic Project Team's discretion.

  • Bayer shall use commercially reasonable efforts to advance the Lead Structures chosen in the Exploratory Research Phase meeting the minimum criteria set forth in the Strategic Project Manual (as modified by the Research Plan) into Development Candidates.

  • The Lead Structures Engineer shall have previous experience in leading the design of extradosed or cable stayed bridges.

  • Scope of Services 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 ▇▇ ▇▇▇▇ ▇▇▇▇▇▇▇ Engineer ▇▇▇▇▇▇▇▇▇▇ ▇▇▇▇▇▇, PE Lead Structures Engineer ▇▇▇▇▇▇ ▇▇▇▇▇▇▇▇, PE Lead Environmental Planner ▇▇▇▇▇ ▇▇▇▇▇▇▇▇▇▇ QA/QC Engineer ▇▇▇▇ ▇▇▇▇▇▇▇▇, PE The Project Manager shall be a registered civil engineer in the State of California.

  • Bayer shall use commercially reasonable efforts to find Hits, advance the Hits to Lead Structures and advance the Lead Structures to the Strategic Project Phase using the guidelines set forth in the Strategic Project Manual.