Lead Nomination definition

Lead Nomination means the preclinical development activities performed for each Collaboration Target at the beginning of Part 1 and for Collaboration Targets selected in Part 2 after Target Validation with the goal to identify Collaboration Compounds which satisfy the Lead Series Identified Criteria.
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Examples of Lead Nomination in a sentence

  • From Lead Nomination onwards and throughout Lead Optimization, the structures of Other Compounds and Collaboration Compounds in the Lead Optimization phase shall be shared with the Roche project team members (including Collaboration Compounds meeting Lead Series Identified Criteria, CLS Criteria and CCS Criteria).

  • Roche and Blueprint hereby agree as follows: The 5th paragraph of Section 4.1.5 of the Agreement shall be deleted in its entirety and replaced by the following: Two chemistry experts at Roche (“Insulated Chemistry Experts”) shall be designated in writing by Roche to review structures of Other Compounds and Collaboration Compounds at the start of the collaboration and throughout the Lead Nomination phase.

  • From Lead Nomination onwards and throughout Lead Optimization, the structures of Other Compounds and Collaboration Compounds in the Lead ​ ​ Optimization phase shall be shared with the Roche project team members (including Collaboration Compounds meeting Lead Series Identified Criteria, CLS Criteria and CCS Criteria).

  • Roche and Blueprint hereby agree as follows: ​ The 5th paragraph of Section 4.1.5 of the Agreement shall be deleted in its entirety and replaced by the following: Two chemistry experts at Roche (“Insulated Chemistry Experts”) shall be designated in writing by Roche to review structures of Other Compounds and Collaboration Compounds at the start of the collaboration and throughout the Lead Nomination phase.

  • At Lead Nomination and/or during Lead Optimization, as per Section 8.4, the JRC will also recommend whether Roche’s chemistry resources should be included in Lead Optimization to address issues including BPM resource constraints or to assist with problem-solving.

  • Once accepted, the Lead Nomination Form will be valid until the earlier of (a) expiration of 12 months, or (b) expiration of this Agreement.

  • Lead Nomination Forms must be submitted at least one week prior to the execution date of a signed contract between the lead and Silver Lining to be eligible for consideration.

  • Submission of a lead ("Lead") by a Partner will be made through submission of a completed form ("Lead Nomination Form"), instructions for which are attached hereto as Attachment A, so that Silver Lining may contact the prospective customer and proceed with discussions.

  • Lead Nomination Forms submitted for prospective customers whom Silver Lining has been working with or is in discussions with prior to receipt of the Lead will normally be rejected.

  • Roche and Blueprint hereby agree as follows: The 5th paragraph of Section 4.1.5 of the Agreement shall be deleted in its entirety and replaced by the following: Two chemistry experts at Roche (“Insulated Chemistry Experts”) and two metabolism experts (“Insulated Pharmaceutical Sciences Experts”) shall be designated in writing by Roche to review structures of Other Compounds and Collaboration Compounds at the start of the collaboration and throughout the Lead Nomination phase.