Lead Molecule definition
Examples of Lead Molecule in a sentence
If Licensee exercises the Back-up Option prior to the delivery by K▇▇▇▇▇ to Licensee of the Phase I Data Package for the Lead Molecule and then subsequently elects to exercise the Lead Option, Licensee shall pay to Kineta the difference between the Option Exercise Payment for the Lead Option and the Back-up Option or [***].
In the event the parties agree to proceed with the ---------------------------- Development of one or more Candidate Compounds pursuant to Section 5.2 (i) or Section 5.2 (ii) above, the party responsible for Progression of the chosen Candidate Compounds from a Lead Molecule will be reimbursed 50% of its total, fairly allocated costs incurred during such Progression by the other party, including but not limited to costs incurred related to support provided by the other party during such Progression.
Other representatives of each Party involved with the Collaboration Molecule, Lead Molecule or Licensed Product may attend meetings as non-voting participants, subject to the confidentiality provisions set forth in ARTICLE 10.
For clarity, JBI shall not have a license from Scholar Rock to Commercialize any Collaboration Molecule, Lead Molecule or Licensed Product unless and until JBI has exercised its License Option in accordance with Section 2.2 for Collaboration Molecules with such Pharmacological Profile.
Regardless of the Progression ---------------------------------- Strategy agreed upon pursuant to Section 5.1 above, at any time a party determines that a Lead Molecule has developed into a Candidate Compound, such party shall promptly notify the P.12 other party and within 90 days of such notice the parties shall attempt to agree upon the Development Strategy to be employed with respect to such Candidate Compound.
On a Pharmacological Profile-by-Pharmacological Profile basis, Scholar Rock will notify the Program Committee upon designating that a Collaboration Molecule should be a Lead Molecule for such Pharmacological Profile based upon satisfaction of the Lead Criteria.
For the avoidance of doubt, it is understood and agreed that use by and on behalf of Licensee of the Lead Molecule to conduct research on any and all molecules, including without limitation use of the Lead Molecule as a research tool, is permitted during such period.
In the event that, following Deconvolution, a Lead Extract is determined not to contain a Lead Molecule or if, after reasonable effort a Lead Molecule cannot be deconvoluted, or in the event a Lead Extract has not entered into Deconvolution within [ ]* of designation by the Committee as a Lead Extract, any encumbrances placed upon Phytera's use of such Lead Extract outside this Agreement shall lapse and Phytera shall be free to use the Lead Extract in other research programs.
The following restrictions shall apply on a Pharmacological Profile-by-Pharmacological Profile basis with respect to any academic, scientific, medical or other publication or presentation or other disclosure by Scholar Rock or JBI that contains or refers to or otherwise relates to any Collaboration Molecule, Lead Molecule or Licensed Product prior to exercise of the License Option for such Pharmacological Profile.
Except as otherwise set forth in a corresponding Research Plan, EXS shall deliver a Development Candidate Data Package for the Lead Molecule for an Approved Collaboration Target first and shall deliver a Development Candidate Data Package with respect to [***] Back-Up Molecules [***] for such Approved Collaboration Target by no later than [***] months following the delivery of the Development Candidate Data Package for the Lead Molecule.