LD50 definition

LD50 means the median lethal dose of a chemical, which is the amount of a test material per body weight that, when administered, results in fifty percent (50%) mortality to the organisms during a specified time period.

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LD50 means a dose of a substance that produces death in 50 per cent of a population of experimental animals. It is usually expressed as milligrams per kilogram (mg/kg) of body weight.

LD50 means the median lethal dose which is the sta- tistical estimate of the dosage of a substance necessary to kill 50% of an infinite population of test animals as determined from expo- sure to the substance, by any route other than inhalation, of a sig- nificant number from that population.

Examples of LD50 in a sentence

Barrier will provide information (i.e. LD50, toxicity, solubility, lot size, fill volume, product min dose/70Kg patient) and establish cleaning limits with DSM assistance.
In addition, the dose range we have selected with this chimeric protein hIL13 PE38QQR will define the LD10 and LD50 doses in nude mice.
Provision is made for the classification of a particular compound to be adjusted if, for any reason, the acute hazard to man differs from that indicated by LD50 assessments alone.
Only if this is not available should the formula be used, as shown in Part I on page 3 to extrapolate the LD50 of the formulation from that of the technical product.
Where the dermal LD 1 value of a compound is such that it would place it in a more restrictive class than the oral LD50 value would indicate, the compound will always be classified in the more restrictive class.

More Definitions of LD50

LD50 means the median lethal dose of a chemical, which is the amount of a test material per body weight which, that,

LD50 means a dose of a toxic substance which is lethal to 50% of the exposed organisms in a given time period.

LD50 means the amount of a material, given all at once, which causes the death of 50% (one half) of a group of test animals.

LD50 means that dose of a substance administered to test organisms that is lethal to 50 percent of a population of exposed organisms in a given time period. "LD50-oral rat" or "oral rat" means that dose of a substance, administered orally, that is lethal to 50 percent of a population of exposed rats in a given time period.

LD50 means the single dose of a substance that, when administered by a defined route in an animal assay, is expected to cause the death of at least 50% of a defined population of animals.

LD50 means, with respect to a pesticide, the LD50 approved in the registration of the pesticide under the Pest Control Products Act (Canada);

LD50 means the single dose of a mixture or substance that, when administered by a particular exposure route in an animal study, is expected to cause the death of 50.0% of a given animal population.