JAK definition

JAK means human Jak Tyrosine Kinase.
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JAK means JAK Pacific Video Warranty and Repair Services, Inc., a California corporation, with its principal place of business located at 1220 Xxxxxxxx Xxxxxx, Xxxxx 000, Xxxxxxxxxx, Xxxxx 00000, xxd its successors and assigns.
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JAK means JAK Opportunities LLC, with offices located at 00 Xxxxx Xxxxxx, 0000 Xxx Xxxx, Xxx Xxxx 00000.
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Examples of JAK in a sentence

  • Use of Opzelura in combination with therapeutic biologics, other JAK inhibitors, or potent immunosuppressants, such as azathioprine or cyclosporine, is not recommended.In October 2021, Incyte announced the validation of the European Marketing Authorization Application (MAA) for ruxolitinib cream as a potential treatment for adolescents and adults (age >12 years) with non-segmental vitiligo with facial involvement.

  • Use of Opzelura in combination with therapeutic biologics, other JAK inhibitors, or potent immunosuppressants, such as azathioprine or cyclosporine, is not recommended.In Europe, Opzelura (ruxolitinib) cream 15mg/g is approved for the treatment of non-segmental vitiligo with facial involvement in adults and adolescents from 12 years of age.

  • Inhibiting these JAK enzymes interferes with the JAK/STAT signaling pathway and, in turn, modulates the activity of a wide range of pro-inflammatory cytokines.

  • The name under which the Corporation was originally incorporated was JAK InterCo, Inc.

  • Xxxxx Title: Sole Director of its Manager JAK LLC By: /s/ Xxxxxxxx X.

  • Except as specifically provided in that letter agreement dated November 13, 2009, Incyte shall remain responsible for the supply of preclinical and clinical material of JAK Licensed Product for use in the conduct of study 352, until such time as the JAK JDC determines that Novartis should assume responsibility for study 352.

  • Novartis and Incyte shall each appoint a person from among its representatives on the JAK JDC to serve as the co-chairperson of the JAK JDC.

  • At such JSC meeting, such Party shall present the data supporting its contention that such compound would reasonably be expected not to compete with existing Licensed Products and therefore formally request that such compound be designated either a c-MET Excluded Compound or a JAK Excluded Compound.

  • Xxxxxx xxXxxxxxx President & CEO EXHIBIT A Licensed Patents The Medical College of Georgia and its Research Institute (“MCGRI”) hold certain title and rights in a joint invention on the alpha 7 nicotinic receptor agonists and the JAK pathway with Targacept, Inc., specifically: Case #016-02: “Methods and Compositions for Treatment of Central Nervous System Disorders” Inventors: Drs.

  • JAK inhibitors function by inhibiting the activity of one or more of the Janus kinase family of enzymes (JAK1, JAK2, JAK3, TYK2) that play a key role in cytokine signaling.

Related to JAK

  • MR means the mechanical rights granted in clauses 2.1.1 and 2.1.2.

  • PAT means a document or product accessibility template, including any Information Technology Industry Council Voluntary Product Accessibility Template or VPAT®, that specifies how information and software products, such as websites, applications, software and associated content, conform to WCAG 2.0 Level AA.

  • SADC means the Southern African Development Community;

  • coronavirus means severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2);

  • Bruce Waterfall resign his xxxxxxon xxxx the Fund, or sell his interest therein, he shall immediately notify the Board and the Commission, and cause his successor to file appropriate Nevada gaming applications with the Board and the Commission.

  • STU means the Board or the Government company notified by the respective State Government under Sub-section (1) of Section 39 of the Act;

  • McDaniel means McDaniel & Associates Consultants Ltd.

  • EMMA means the Electronic Municipal Market Access system as described in 1934 Act Release No. 59062 and maintained by the MSRB for purposes of the Rule.

  • PETE means polyethylene terephthalate, labeled by the SPI code #1.

  • Diocese means the Church of England diocese in which the Academies are situated;

  • Sproule means Sproule Associates Limited;

  • DARO means "days after the effective date for award of the contractual action".

  • HBV means hepatitis B virus.