Internal standard definition

Internal standard means an analyte added to calibra- tion standards, blanks, quality control and analytical samples as a reference for evaluating and controlling the precision and bias of an analytical test. Responses of internal standards are used to adjust the quantities of analytes reported in tests that employ the standards.
Internal standard means a known concentration of standard added to a sample or quality control sample as a refer- ence for evaluating and controlling the precision and bias of the analytical method.
Internal standard means a known amount of standard added to a test portion of a sample as a reference for evaluating and controlling the precision and bias of the applied analytical method. (NELAC)

Examples of Internal standard in a sentence

  • Internal standard operating procedures (SOPs) may be referenced provided they are available for audit review.

  • Internal standard (ISTD) solutions for 13C4 isotopically labeled phthalate metabolites were purchased from Cambridge Isotopes Laboratories (Cambridge, MA, USA).

  • Internal standard analytes were used for quantification of sample analytes detected.


More Definitions of Internal standard

Internal standard means a standard specification prepared for local use by a local administration, a Government department, a statutory corporation or any other person or association below thenational level level;
Internal standard means a known concentration of an analyte added to calibration standards, blanks, laboratory control samples, matrix spikes, matrix spike duplicates, replicate samples, and environmental samples as a reference for evaluating a nd controlling the precision and bias of a method.
Internal standard means a standard specification prepared for local use by a local administration, a Government department, a statutory corporation or any other person or association below the
Internal standard means a chemical substance that is similar, but not identical to, the analyte or analytes of interest that are added to a sample at a known concentration. An internal standard is used for quantitation of 1,4-dioxane and to account for matrix effects or variability in instrument response by normalizing the response of 1,4-dioxane, or both, thereby decreasing measurement bias to the extent that their behavior mimics that of 1,4-dioxane.

Related to Internal standard

  • national standard means a standard adopted by a national standardisation organisation and made available to the general public;

  • international standard means a standard adopted by an international standardisation organisation and made available to the general public;

  • National Standards means the document entitled “National Standards for the Volatile Organic Compound Content of Canadian Commercial/Industrial Surface Coating Products Automotive Refinishing, October 1998, PN 1288" and published by the Canadian Council of Ministers of the Environment;

  • Technical standard means a document that specifies design, predicted performance and operation and maintenance specifications for a material, device or method.

  • Technical Standards means the technical standards set out in paragraph 2.4 of the Order Form;