Induration definition
Examples of Induration in a sentence
The TST is considered positive if: • Induration of ≥ 10 mm for all healthy refugees • Induration of ≥ 5 mm in refugees with HIV, known close contact with someone with infectious TB, chest X-ray consistent with prior TB, organ transplant recipient, or immunosuppressed The two FDA-approved IGRAs are the QuantiFERON®-TB Gold In-Tube test (QFT-GIT) and T-SPOT®.TB test (T-Spot)(33).
ESAT-6 versus tuberculin as skin test 195 Redness in response to rdESAT-6 (mm) 70 60 50 40 30 10 In vitro IFN-gamma response to ESAT-6 (IU/mL) Induration in response to rdESAT-6 (mm) 25 20 15 10 5 In vitro IFN-gamma response to ESAT-6 (IU/mL) Figure 4 Relation between in vitro responses to ESAT-6 and in vivo skin test responses to rdESAT-6.
DOUBTFUL REACTION -- Induration measuring 5 to 9 mm indicated a doubtful reaction.
NEGATIVE REACTION -- Induration of less than 5 mm is considered negative.
Induration sizes of > 15 mm are more likely to be the result of MTBI than prior BCG vaccination, especially if the subject was immunized in infancy and the vaccination occurred more than 10 prior to IGRA testing (86, 189).