DM1 definition
Examples of DM1 in a sentence
IMMUNOGEN shall own all data, results and all other information arising from IMMUNOGEN’s activities relating to the manufacture and supply of MAY Compounds (including ansamitocin P-3 and DM1) to GENENTECH, and all of the foregoing information, documentation and materials shall be considered Confidential Information and Technology solely owned by IMMUNOGEN.
ADCs incorporating ZymeLink have demonstrated a greater therapeutic window (range of doses that are both efficacious and tolerable) in preclinical testing than those incorporating the commonly used ADC payloads DM1 or MMAE.
Both Parties will conduct business in a manner that reflects favorably at all times on the products containing DM1, goodwill, and reputation of the other Party.
During the Term of Employment, the Executive shall be entitled an allotment of 25 days of paid time off per calendar year, prorated for partial years, or such greater amount provided for pursuant to the Company’s paid time off policy, as in effect from time to time, in each case, subject to the terms and conditions of such policy.
For clarity, if Sarepta makes the payment contemplated in the foregoing clause (a)(i)(B)(2), then, upon ▇▇▇▇▇▇▇▇▇’s receipt of such payment, Sarepta will have no further obligations under Section 8.3.1(a) (DM1 Program Development Milestones).
The Licensed C1 Compounds, Licensed C1 Products, Licensed C2 Compounds, and Licensed C2 Products include all compounds and products owned or in-licensed by Arrowhead or any of its Affiliates as of such respective date that are Directed To ATXN1, ATXN2, ATXN3, DM1, DUX4, MMP7, or HTT.
The following ▇▇▇▇▇ chart illustrates the key deliverables and the delivery milestones (e.g. DM1) for the GDE FF programme at GHNT, broken down into its component work streams and individual projects.
With respect to the DM1 Program, Sarepta will make one-time, non-refundable [***], and non-creditable milestone payments to Arrowhead of: (i) $100,000,000 upon the achievement of the DM1 First Development Milestone Event (the “DM1 First Development Milestone Payment”), and (ii) $200,000,000 upon the achievement of the DM1 Second Development Milestone Event (the “DM1 Second Development Milestone Payment”) in accordance with Section 8.3.1(b) (DM1 Program Development Milestones).
Commented [DM1]: I think this section was renumbered 66.0301 in the Wisconsin Statutes.
Vertex desires to obtain from Company, and Company desires to grant to Vertex, an exclusive license to certain AAV Capsids Controlled by Company for use in DMD and DM1 (each as defined below), and exclusive licenses to certain other AAV Capsids Controlled by Company for use in Cystic Fibrosis and [***], which licenses with respect to Cystic Fibrosis and [***] may not be practiced by Vertex until the exercise of the relevant Option and the payment of the relevant Option fee (as set forth below).