CRISPR/Cas System definition
CRISPR/Cas System means a clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) protein system that comprises (a) [***] and (b) [***].
CRISPR/Cas System means one or more of the following components: (a) a guide RNA element, wherein said guide RNA element can be a guide RNA or a polynucleotide(s) encoding such guide RNA, that is complementary to a Target gene or safe harbor locus, and which is designed to be used with a naturally occurring or engineered clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) protein, (b) a naturally occurring or engineered CRISPR-associated nuclease element, wherein said nuclease element can be a nuclease protein (such as Cas protein) or a polynucleotide(s) encoding such protein, and which can be active or deactivated, and which can be complexed to an activation or repressor domain and (c) an HDR donor template, wherein said HDR donor template can be a single or double stranded polynucleotide(s), which is designed to be used with a nuclease and guide.
CRISPR/Cas System. (including all individual components thereof) means a system comprising a CRISPR (clustered regularly interspaced short palindromic repeats) guide RNA and a vector encoding a Cas (CRISPR-associated) nuclease. Non-limiting examples of CRISPR, Cas, and the CRISPR/Cas system can be found in [***] as well as references cited in Schedule 1.26.
Examples of CRISPR/Cas System in a sentence
Vertex and CRISPR desire to enter into a license agreement to enable Vertex to research, develop, manufacture and commercialize certain products for the treatment of diabetes using gene editing [***], including the CRISPR/Cas System (as defined below).
More Definitions of CRISPR/Cas System
CRISPR/Cas System means a clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR- associated (Cas) protein system that comprises (a) [***] and (b) [***].