CRBN definition
Examples of CRBN in a sentence
For the avoidance of doubt, the commercialisation by ICR and CRT of a Duplicate Compound that is directed against a target other than CRBN binding and has only residual or minimal binding to CRBN such that such residual or minimal binding is not necessarily required for its main therapeutic activity and/or has not been pursued in development shall be permitted.
CRT and ICR recognise the need to protect the confidentiality of the chemical structures of the Compound Library and pre-clinical candidates, and the Programme Know How that is the data associating that Unencumbered CRT/ICR Background Hit Compounds (where identified by chemical structure) bind CRBN.
The Parties acknowledge that CRBN cannot issue any settlement payments pursuant to Section 3.1 and 3.2 above until after CRBN receives the requisite W-9 forms from EHA’s counsel.
The Notice alleged that CRBN had violated Proposition 65 by failing to sufficiently warn consumers in California of the health hazards associated with exposures to lead contained in Covered Products.
Commencing on the Effective Date, CRBN agrees any Covered Product sold or distributed for sale in California, shall contain a Proposition 65 warning.
On or around September 24, 2024, EHA served CRBN, the California Attorney General, and certain other public enforcement agencies with a 60-Day Notice of Violation of Proposition 65 (“Notice”).
Pursuant to Health and Safety Code § 25249.7(b)(2), and in settlement of all claims alleged in the Notice or referred to in this Settlement Agreement, CRBN agrees to pay two thousand dollars ($2,000.00) in civil penalties.
Under these legal principles, CRBN agrees to pay eighteen thousand dollars ($18,000.00) to EHA and its counsel for all fees and costs incurred in investigating, bringing this matter to the attention of CRBN, and negotiating a settlement.
Nothing in this Settlement Agreement shall be construed as an admission by CRBN of any fact, finding, conclusion, issue of law or violation of law, nor shall compliance with this Settlement Agreement constitute or be construed as an admission by CRBN of any fact, finding, conclusion, issue of law or violation of law, such being specifically denied by CRBN.
CRBN denies the material, factual, and legal allegations in the Notice and maintains that all of the products it sold and/or distributed for sale in California, including Covered Products, have been, and are, in compliance with all laws.