Conjugate Technology definition

Conjugate Technology means chemistry designed to enhance targeting or uptake of antisense drugs to specific tissues and cells. Conjugate Technology includes N-acetylgalactosamine (GalNAc) ligand conjugates capable of binding to the asialoglycoprotein receptor (ASGP-R) and enhancing the targeting or uptake of antisense drugs to the liver.
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Conjugate Technology means a group of atoms covalently bound to an Oligonucleotide designed to enhance one or more properties of the Oligonucleotide, such as targeting of antisense drugs to specific tissues and cells. Conjugate Technology includes N-acetylgalactosamine (GalNAc) ligand conjugates capable of binding to the asialoglycoprotein receptor (ASGP-R) and enhancing the targeting of antisense drugs.
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Conjugate Technology has the meaning ascribed to such definition in the […***…]11.
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Examples of Conjugate Technology in a sentence

  • To the extent Novartis intends to make any claims in a Product label or regulatory filing that are class generic to Oligonucleotides, Akcea’s or its Affiliate’s generation 2.0 or 2.5 chemistry platform(s), Conjugate Technology, or any other Akcea technology included in a Product, Novartis will provide such claims and regulatory filings to Akcea in advance and will [***] any proposals and comments made by Akcea (or its Affiliates).

  • To the extent Bayer intends to make any claims in a Product label or regulatory filing that are class generic to ASOs, Isis’ generation 2.0 or 2.5 chemistry platform(s), Conjugate Technology, or any other Isis technology included in a Product, Bayer will provide such claims and regulatory filings to Isis in advance and will consider in good faith any proposals and comments made by Isis.

  • In addition, to the extent Akcea intends to make any claims in a label or regulatory filing for a Product that are class generic to antisense oligonucleotides, Ionis’ generation 2.0 or 2.5 chemistry platform(s), or Conjugate Technology the Regulatory Sub-Committee will adopt Ionis’ language for such class generic claim in such label or regulatory filing.

  • For clarity, Pfizer Product-Specific Patent Rights do not include any Patent Rights claiming formulation technology or delivery devices (other than Conjugate Technology).

  • Pursuant to the […***…]179, the Conjugate Technology and the Conjugate Patent Rights (defined below) are owned jointly by the Parties, with […***…]180 provided, for clarity, that Zymeworks’ exercise of such right is subject to Sections 2.1 and 2.2. For clarity, this Agreement does not supersede the […***…]181 and, except as expressly set forth herein or otherwise agreed in writing by the Parties, the terms and conditions of the […***…]182 remain in full force and effect.

  • About Fleximer Antibody-Drug Conjugate Technology Mersana’s next-generation Fleximer® antibody-drug conjugate (ADC) technology is based on the Company’s proprietary biodegradable polymer system, known as Fleximer, and a wide variety of linkers that allow for the attachment of an extensive range of anti-tumor payloads to Fleximer.

  • To the extent PTC intends to make any claims in a Product label or regulatory filing for a Product in the PTC Territory that are class generic to antisense oligonucleotides, Ionis’ generation 2.0 or 2.5 chemistry platform(s), or Conjugate Technology, PTC will provide Akcea with such proposed claims for Akcea’s review and will [**] for such class generic claims in such label or regulatory filing.

  • For clarity, Pfizer Core Technology Know-How does not include any Know-How covering formulation technology or delivery devices (other than Conjugate Technology).

  • To the extent PTC intends to make any claims in a Product label or regulatory filing for a Product in the PTC Territory that are class generic to antisense oligonucleotides, Ionis’ generation 2.0 or 2.5 chemistry platform(s), or Conjugate Technology, PTC will provide Akcea with such proposed claims for Akcea’s review and will [***] for such class generic claims in such label or regulatory filing.

  • For clarity, Pfizer Product-Specific Know-How does not include any Know-How covering formulation technology or delivery devices (other than Conjugate Technology).