CMP-001 definition

CMP-001 means the Checkmate proprietary TLR9 Agonist (Toll-Like Receptor 9 Agonist) known as CMP-001.
View Source

Examples of CMP-001 in a sentence

  • CMP-001 will be switched to every 2 week IT dosing to match avelumab dosing starting with Cycle 2.

  • Each study arm will begin with a 6-12 patient safety lead-in, followed by an expansion of patients up to 20 at a tolerable dose of CMP-001.

  • Checkmate and BMS desire to collaborate on clinical trials of a combination therapy using Checkmate’s proprietary TLR9 Agonist (Toll-Like Receptor 9 Agonist) known as CMP-001 and BMS’ PD-1 antagonist known as Nivolumab.

  • As shown in the schematic below: Arm F1 will include a safety lead-in cohort of 6 to 12 patients treated with 2 weekly doses of SC CMP-001 on Cycle 1 Day -14 and Day -7, followed by 3rd week intratumoral (IT) injections of CMP-001 on Cycle 1 Day 1, with avelumab administered on Day 2 of Cycle 1.